Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | carboxylesterase | 0.0046 | 0.0859 | 0.0859 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0046 | 0.0859 | 0.0859 |
Echinococcus granulosus | geminin | 0.017 | 0.581 | 0.581 |
Onchocerca volvulus | 0.0046 | 0.0859 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0859 | 0.0859 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0046 | 0.0859 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0046 | 0.0859 | 0.0859 |
Echinococcus multilocularis | acetylcholinesterase | 0.0274 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0859 | 0.0859 |
Loa Loa (eye worm) | carboxylesterase | 0.0274 | 1 | 1 |
Onchocerca volvulus | 0.0046 | 0.0859 | 0.5 | |
Echinococcus multilocularis | neuroligin | 0.0046 | 0.0859 | 0.0859 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0046 | 0.0859 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0859 | 0.0859 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0046 | 0.0859 | 0.0859 |
Onchocerca volvulus | 0.0046 | 0.0859 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.0859 | 0.0859 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0046 | 0.0859 | 0.0859 |
Echinococcus multilocularis | geminin | 0.017 | 0.581 | 0.581 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0859 | 0.0859 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0859 | 0.0859 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.581 | 0.581 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0046 | 0.0859 | 0.0859 |
Brugia malayi | Carboxylesterase family protein | 0.0274 | 1 | 1 |
Echinococcus granulosus | neuroligin | 0.0046 | 0.0859 | 0.0859 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0046 | 0.0859 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0274 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0859 | 0.0859 |
Loa Loa (eye worm) | carboxylesterase | 0.0046 | 0.0859 | 0.0859 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0046 | 0.0859 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0859 | 0.0859 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.0859 | 0.0859 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0859 | 0.0859 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0046 | 0.0859 | 0.5 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0859 | 0.0859 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0859 | 0.0859 |
Schistosoma mansoni | acetylcholinesterase | 0.0046 | 0.0859 | 0.0859 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0274 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0859 | 0.0859 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.0859 | 0.0859 |
Schistosoma mansoni | gliotactin | 0.0046 | 0.0859 | 0.0859 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0274 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0046 | 0.0859 | 0.5 |
Onchocerca volvulus | 0.0046 | 0.0859 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.581 | 0.581 |
Echinococcus multilocularis | acetylcholinesterase | 0.0274 | 1 | 1 |
Onchocerca volvulus | 0.0046 | 0.0859 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0274 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0046 | 0.0859 | 0.0859 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0046 | 0.0859 | 0.0859 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0046 | 0.0859 | 0.0859 |
Loa Loa (eye worm) | hypothetical protein | 0.0274 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0274 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0274 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0274 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0859 | 0.0859 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.