Detailed information for compound 874120

Basic information

Technical information
  • TDR Targets ID: 874120
  • Name: 5-chloro-N-(2-dimethylaminoethyl)-N-(4-fluoro -1,3-benzothiazol-2-yl)thiophene-2-carboxamid e
  • MW: 383.891 | Formula: C16H15ClFN3OS2
  • H donors: 0 H acceptors: 2 LogP: 4.84 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCN(C(=O)c1ccc(s1)Cl)c1sc2c(n1)c(F)ccc2)C
  • InChi: 1S/C16H15ClFN3OS2/c1-20(2)8-9-21(15(22)12-6-7-13(17)23-12)16-19-14-10(18)4-3-5-11(14)24-16/h3-7H,8-9H2,1-2H3
  • InChiKey: APADPGFJAHTVCS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-chloro-N-(2-dimethylaminoethyl)-N-(4-fluoro-1,3-benzothiazol-2-yl)-2-thiophenecarboxamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus biogenic amine 5HT receptor 0.0054 0.0619 0.3516
Echinococcus granulosus serotonin receptor 0.0054 0.0619 0.3516
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0619 0.3516
Brugia malayi Melatonin receptor type 1A 0.0054 0.0619 1
Mycobacterium ulcerans NADH dehydrogenase subunit H 0.0148 0.176 1
Echinococcus multilocularis orexin receptor type 2 0.0054 0.0619 1
Echinococcus granulosus g-protein coupled receptor 0.0054 0.0619 0.3516
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus orexin receptor type 2 0.0054 0.0619 0.3516
Schistosoma mansoni neuropeptide F-like receptor 0.0054 0.0619 0.3516
Schistosoma mansoni alpha-1 adrenergic receptor 0.0054 0.0619 0.3516
Schistosoma mansoni opsin-like receptor 0.0054 0.0619 0.3516
Brugia malayi hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni biogenic amine receptor 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0619 0.3516
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Brugia malayi hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0054 0.0619 0.3516
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0619 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0619 0.3516
Echinococcus multilocularis g-protein coupled receptor 0.0054 0.0619 1
Echinococcus granulosus G protein coupled receptor 139 0.0054 0.0619 0.3516
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0054 0.0619 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0054 0.0619 0.3516
Entamoeba histolytica modulator of drug activity B homolog, putative 0.0207 0.247 0.5
Echinococcus granulosus 7TM GPCR rhodopsin 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Loa Loa (eye worm) neuropeptide F receptor 0.0054 0.0619 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0054 0.0619 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0054 0.0619 0.3516
Onchocerca volvulus 0.0054 0.0619 1
Brugia malayi hypothetical protein 0.0054 0.0619 1
Brugia malayi hypothetical protein 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0003 0.0003 0.0047
Echinococcus multilocularis neuropeptide receptor 0.0054 0.0619 1
Brugia malayi sulfakinin receptor protein 0.0054 0.0619 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0054 0.0619 1
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Brugia malayi hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni neuropeptide receptor 0.0054 0.0619 0.3516
Brugia malayi neuropeptide F receptor 0.0054 0.0619 1
Onchocerca volvulus 0.0054 0.0619 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0054 0.0619 1
Onchocerca volvulus 0.0054 0.0619 1
Echinococcus multilocularis transient receptor potential cation channel 0.0003 0.0003 0.0047
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0054 0.0619 1
Echinococcus multilocularis allatostatin A receptor 0.0054 0.0619 1
Onchocerca volvulus 0.0054 0.0619 1
Brugia malayi G protein-coupled receptor 0.0054 0.0619 1
Brugia malayi GnHR receptor homolog 0.0054 0.0619 1
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni hypothetical protein 0.0054 0.0619 0.3516
Echinococcus granulosus NADH dehydrogenase subunit 1 0.0148 0.176 1
Onchocerca volvulus 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0619 0.3516
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0054 0.0619 1
Brugia malayi Dopamine receptor protein 2 0.0054 0.0619 1
Trichomonas vaginalis conserved hypothetical protein 0.062 0.7492 0.6669
Schistosoma mansoni opsin-like receptor 0.0054 0.0619 0.3516
Echinococcus multilocularis neuropeptide s receptor 0.0054 0.0619 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0054 0.0619 1
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0619 1
Brugia malayi neuropeptide F receptor 0.0054 0.0619 1
Giardia lamblia NADPH oxidoreductase, putative 0.0827 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0054 0.0619 1
Brugia malayi Serotonin receptor 0.0054 0.0619 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0619 0.3516
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Schistosoma mansoni histamine h1 receptor 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0619 1
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0827 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0619 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0619 0.3516
Onchocerca volvulus 0.0054 0.0619 1
Brugia malayi NADH dehydrogenase subunit 1, identical 0.004 0.0446 0.7187
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0054 0.0619 0.3516
Echinococcus granulosus neuropeptides capa receptor 0.0054 0.0619 0.3516
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0054 0.0619 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0054 0.0619 0.3516
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0054 0.0619 1
Brugia malayi Dopamine receptor protein 1 0.0054 0.0619 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0054 0.0619 0.3516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0619 0.3516
Echinococcus multilocularis sex peptide receptor 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0054 0.0619 1
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Echinococcus multilocularis neuropeptide receptor A26 0.0054 0.0619 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0619 0.3516
Entamoeba histolytica iron-sulfur flavoprotein, putative 0.0207 0.247 0.5
Echinococcus granulosus neuropeptide receptor A26 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus fmrfamide receptor 0.0054 0.0619 0.3516
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Entamoeba histolytica hypothetical protein 0.0207 0.247 0.5
Brugia malayi AKH receptor 0.0054 0.0619 1
Onchocerca volvulus 0.0054 0.0619 1
Schistosoma mansoni neuropeptide receptor 0.0054 0.0619 0.3516
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0619 0.3516
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0619 1
Echinococcus granulosus tm gpcr rhodopsin 0.0054 0.0619 0.3516
Brugia malayi Serotonin receptor 0.0054 0.0619 1
Brugia malayi hypothetical protein 0.004 0.0446 0.7187
Onchocerca volvulus 0.0054 0.0619 1
Schistosoma mansoni hypothetical protein 0.0148 0.176 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0054 0.0619 0.3516
Loa Loa (eye worm) neuropeptide F receptor 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Brugia malayi hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus transient receptor potential cation channel 0.0003 0.0003 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0619 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0054 0.0619 0.3516
Schistosoma mansoni amine GPCR 0.0054 0.0619 0.3516
Schistosoma mansoni amine GPCR 0.0054 0.0619 0.3516
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H) 0.0148 0.176 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0054 0.0619 1
Echinococcus multilocularis serotonin receptor 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Brugia malayi G-protein coupled receptor 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Onchocerca volvulus 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0619 0.3516
Brugia malayi hypothetical protein 0.0054 0.0619 1
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Schistosoma mansoni amine GPCR 0.0054 0.0619 0.3516
Echinococcus granulosus tm gpcr rhodopsin 0.0054 0.0619 0.3516
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0054 0.0619 1
Echinococcus multilocularis G protein coupled receptor 139 0.0054 0.0619 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni neuropeptide F-like receptor 0.0054 0.0619 0.3516
Loa Loa (eye worm) TYRA-2 protein 0.0054 0.0619 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0054 0.0619 0.3516
Schistosoma mansoni transient receptor potential channel 0.0003 0.0003 0.0017
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0054 0.0619 1
Brugia malayi Dopamine receptor 0.0054 0.0619 1
Echinococcus multilocularis fmrfamide receptor 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0054 0.0619 0.3516
Echinococcus granulosus tm gpcr rhodopsin 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0054 0.0619 0.3516
Schistosoma mansoni NADH dehydrogenase subunit 1 0.004 0.0446 0.2531
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase subunit H 0.0148 0.176 0.5
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0054 0.0619 1
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0054 0.0619 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0619 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0054 0.0619 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0619 0.3516
Schistosoma mansoni hypothetical protein 0.0054 0.0619 0.3516
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0054 0.0619 1
Echinococcus multilocularis neuropeptide Y receptor 0.0054 0.0619 1
Brugia malayi hypothetical protein 0.0054 0.0619 1
Brugia malayi putative neuropeptide receptor NPR1 0.0054 0.0619 1
Onchocerca volvulus 0.0054 0.0619 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni neuropeptide receptor 0.0054 0.0619 0.3516
Echinococcus granulosus alpha 1A adrenergic receptor 0.0054 0.0619 0.3516
Brugia malayi RE15519p 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0054 0.0619 0.3516
Schistosoma mansoni biogenic amine receptor 0.0054 0.0619 0.3516
Echinococcus granulosus neuropeptide receptor 0.0054 0.0619 0.3516
Brugia malayi ORL1-like opioid receptor 0.0054 0.0619 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0619 1
Brugia malayi putative neuropeptide receptor 0.0054 0.0619 1
Onchocerca volvulus 0.0054 0.0619 1
Loa Loa (eye worm) G-protein coupled receptor 0.0054 0.0619 1
Echinococcus multilocularis fmrfamide receptor 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni neuropeptide receptor 0.0054 0.0619 0.3516
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0054 0.0619 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus multilocularis short transient receptor potential channel 6 0.0003 0.0003 0.0047
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0619 0.3516
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0054 0.0619 0.3516
Onchocerca volvulus 0.0054 0.0619 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0619 1
Echinococcus multilocularis neuropeptide receptor 0.0054 0.0619 1
Echinococcus granulosus neuropeptides capa receptor 0.0054 0.0619 0.3516
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0054 0.0619 0.3516
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0054 0.0619 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0054 0.0619 0.3516
Brugia malayi G-protein coupled receptor 0.0054 0.0619 1
Echinococcus multilocularis neuropeptides capa receptor 0.0054 0.0619 1
Onchocerca volvulus 0.0054 0.0619 1
Echinococcus multilocularis neuropeptides capa receptor 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus multilocularis serotonin receptor 0.0054 0.0619 1
Echinococcus granulosus sex peptide receptor 0.0054 0.0619 0.3516
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0054 0.0619 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus allatostatin A receptor 0.0054 0.0619 0.3516
Echinococcus granulosus somatostatin receptor 0.0054 0.0619 0.3516
Onchocerca volvulus Neuropeptide F receptor homolog 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Giardia lamblia NADPH oxidoreductase, putative 0.0827 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus neuropeptide receptor 0.0054 0.0619 0.3516
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0054 0.0619 0.3516
Echinococcus multilocularis somatostatin receptor 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus dro:myosuppressin receptor 0.0054 0.0619 0.3516
Schistosoma mansoni adenoreceptor 0.0054 0.0619 0.3516
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0827 1 1
Schistosoma mansoni amine GPCR 0.0054 0.0619 0.3516
Echinococcus granulosus peptide allatostatin:somatostatin 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Onchocerca volvulus 0.0054 0.0619 1
Echinococcus granulosus neuropeptide Y receptor 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni myosin xvIII 0.0054 0.0619 0.3516
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0054 0.0619 0.3516
Schistosoma mansoni amine GPCR 0.0054 0.0619 0.3516
Brugia malayi hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0619 0.3516
Onchocerca volvulus 0.0054 0.0619 1
Brugia malayi NADH dehydrogenase subunit 1 0.004 0.0446 0.7187
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0054 0.0619 1
Schistosoma mansoni biogenic amine receptor 0.0054 0.0619 0.3516
Schistosoma mansoni hypothetical protein 0.0054 0.0619 0.3516
Brugia malayi larval opioid receptor 0.0054 0.0619 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0054 0.0619 1
Schistosoma mansoni hypothetical protein 0.0054 0.0619 0.3516
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Onchocerca volvulus 0.0054 0.0619 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0619 0.3516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0054 0.0619 0.3516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0619 0.3516
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0619 0.3516
Echinococcus multilocularis transient receptor potential cation channel 0.0003 0.0003 0.0047
Echinococcus granulosus g protein coupled receptor 0.0054 0.0619 0.3516
Echinococcus granulosus neuropeptide Y receptor 0.0054 0.0619 0.3516
Brugia malayi follicle stimulating hormone receptor 0.0054 0.0619 1
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0827 1 1
Echinococcus granulosus g protein coupled receptor 0.0054 0.0619 0.3516
Echinococcus granulosus neuropeptide s receptor 0.0054 0.0619 0.3516
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0054 0.0619 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0054 0.0619 0.3516
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0054 0.0619 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0054 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0054 0.0619 0.3516
Echinococcus multilocularis neuropeptide FF receptor 2 0.0054 0.0619 1
Schistosoma mansoni opsin-like receptor 0.0054 0.0619 0.3516
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0619 0.3516
Echinococcus multilocularis neuropeptide Y receptor 0.0054 0.0619 1
Trichomonas vaginalis conserved hypothetical protein 0.0827 1 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus g protein coupled receptor 0.0054 0.0619 0.3516
Loa Loa (eye worm) G-protein coupled receptor 0.0054 0.0619 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0054 0.0619 0.3516
Echinococcus granulosus short transient receptor potential channel 6 0.0003 0.0003 0.0017
Loa Loa (eye worm) NADH dehydrogenase subunit 1 0.004 0.0446 0.72
Loa Loa (eye worm) hypothetical protein 0.0054 0.0619 1
Brugia malayi hypothetical protein 0.0054 0.0619 1
Echinococcus granulosus hypothetical protein 0.0054 0.0619 0.3516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0619 0.3516
Onchocerca volvulus 0.0054 0.0619 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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