Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Cyclin fold protein 1, putative | 0.0028 | 0.1412 | 0.2194 |
Trichomonas vaginalis | cyclin D, putative | 0.0117 | 0.6436 | 0.585 |
Entamoeba histolytica | cyclin, putative | 0.0117 | 0.6436 | 1 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.018 | 1 | 1 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.0028 | 0.1412 | 0.1599 |
Trypanosoma brucei | mitotic cyclin | 0.0028 | 0.1412 | 0.1531 |
Echinococcus granulosus | cyclins | 0.0117 | 0.6436 | 0.718 |
Echinococcus granulosus | cyclin B | 0.0117 | 0.6436 | 0.718 |
Echinococcus multilocularis | ankyrin repeat protein | 0.0158 | 0.8777 | 0.9781 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0028 | 0.1412 | 0.2181 |
Echinococcus granulosus | cyclin b3 | 0.0117 | 0.6436 | 0.718 |
Leishmania major | cyclin 9, putative | 0.0028 | 0.1412 | 0.1531 |
Echinococcus granulosus | cyclin y | 0.0028 | 0.1412 | 0.1566 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0028 | 0.1412 | 0.2181 |
Leishmania major | mitotic cyclin, putative | 0.0028 | 0.1412 | 0.1531 |
Trypanosoma brucei | cyclin 9 | 0.0028 | 0.1412 | 0.1531 |
Leishmania major | cyclin | 0.0117 | 0.6436 | 1 |
Echinococcus multilocularis | cyclins | 0.0117 | 0.6436 | 0.7169 |
Onchocerca volvulus | Cyclin L homolog | 0.0028 | 0.1412 | 0.1531 |
Onchocerca volvulus | 0.0028 | 0.1412 | 0.1531 | |
Schistosoma mansoni | cyclin l | 0.0028 | 0.1412 | 0.1599 |
Echinococcus multilocularis | calcium activated potassium channel | 0.0006 | 0.0169 | 0.0177 |
Schistosoma mansoni | cyclin B3 | 0.0117 | 0.6436 | 0.733 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0504 | 0.0768 |
Echinococcus granulosus | calcium activated potassium channel | 0.0006 | 0.0169 | 0.0177 |
Trichomonas vaginalis | cyclin D, putative | 0.0117 | 0.6436 | 0.585 |
Echinococcus granulosus | cyclins | 0.0028 | 0.1412 | 0.1566 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0117 | 0.6436 | 0.718 |
Schistosoma mansoni | dihydropteridine reductase | 0.0012 | 0.0504 | 0.0563 |
Loa Loa (eye worm) | oxidoreductase | 0.0012 | 0.0504 | 0.0768 |
Onchocerca volvulus | 0.0117 | 0.6436 | 1 | |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.018 | 1 | 1 |
Leishmania major | mitotic cyclin, putative | 0.0028 | 0.1412 | 0.1531 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0012 | 0.0504 | 0.0768 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0028 | 0.1412 | 0.2181 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.1412 | 0.2181 |
Echinococcus multilocularis | cyclins | 0.0117 | 0.6436 | 0.7169 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.1412 | 0.1599 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0028 | 0.1412 | 0.2181 |
Echinococcus multilocularis | cyclin y | 0.0028 | 0.1412 | 0.1564 |
Trichomonas vaginalis | cyclin A, putative | 0.0117 | 0.6436 | 0.585 |
Echinococcus granulosus | ankyrin repeat protein | 0.0158 | 0.8777 | 0.9796 |
Schistosoma mansoni | cyclin d | 0.0028 | 0.1412 | 0.1599 |
Entamoeba histolytica | cyclin family protein | 0.0117 | 0.6436 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.6436 | 1 |
Loa Loa (eye worm) | CYL-1 protein | 0.0028 | 0.1412 | 0.2181 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.018 | 1 | 1 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0117 | 0.6436 | 0.7169 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.0028 | 0.1412 | 0.1566 |
Echinococcus multilocularis | cyclins | 0.0117 | 0.6436 | 0.7169 |
Echinococcus multilocularis | cyclin B3 1 | 0.0117 | 0.6436 | 0.7169 |
Echinococcus granulosus | cyclin G2 | 0.0028 | 0.1412 | 0.1566 |
Trichomonas vaginalis | cyclin B, putative | 0.0117 | 0.6436 | 0.585 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0012 | 0.0504 | 0.0768 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.0028 | 0.1412 | 0.1564 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0028 | 0.1412 | 0.2181 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0028 | 0.1412 | 0.2181 |
Entamoeba histolytica | cyclin family protein | 0.0117 | 0.6436 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0028 | 0.1412 | 0.0956 |
Schistosoma mansoni | Cyclin fold protein | 0.0028 | 0.1412 | 0.1599 |
Trichomonas vaginalis | cyclins, putative | 0.0117 | 0.6436 | 0.585 |
Plasmodium vivax | cyclin 4, putative | 0.0028 | 0.1412 | 0.0956 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0028 | 0.1412 | 0.2181 |
Schistosoma mansoni | cyclin k | 0.0028 | 0.1412 | 0.1599 |
Trichomonas vaginalis | cyclin B3, putative | 0.0117 | 0.6436 | 0.585 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.0028 | 0.1412 | 0.1531 |
Echinococcus granulosus | cyclins | 0.0117 | 0.6436 | 0.718 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0003 | 0.001 | 0.00000020975 |
Entamoeba histolytica | cyclin C, putative | 0.0028 | 0.1412 | 0.1531 |
Toxoplasma gondii | cyclin domain protein, cyclin H family protein | 0.0028 | 0.1412 | 0.0956 |
Trichomonas vaginalis | cyclin B, putative | 0.0117 | 0.6436 | 0.585 |
Brugia malayi | Cyclin C | 0.0028 | 0.1412 | 0.2181 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0028 | 0.1412 | 0.1531 |
Brugia malayi | hypothetical protein | 0.0028 | 0.1412 | 0.2181 |
Trichomonas vaginalis | cyclins, putative | 0.0117 | 0.6436 | 0.585 |
Giardia lamblia | Hypothetical protein | 0.0117 | 0.6436 | 1 |
Plasmodium falciparum | cyclin 1 | 0.0028 | 0.1412 | 0.0956 |
Toxoplasma gondii | cyclin, N-terminal domain-containing protein | 0.0028 | 0.1412 | 0.0956 |
Trichomonas vaginalis | hypothetical protein | 0.018 | 1 | 1 |
Echinococcus multilocularis | cyclin A3 4 | 0.0028 | 0.1412 | 0.1564 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0003 | 0.001 | 0.00000021007 |
Trichomonas vaginalis | cyclin B, putative | 0.0117 | 0.6436 | 0.585 |
Trypanosoma cruzi | cyclin 6, putative | 0.0117 | 0.6436 | 1 |
Echinococcus multilocularis | Cyclin L1 | 0.0028 | 0.1412 | 0.1564 |
Echinococcus granulosus | cyclins | 0.0117 | 0.6436 | 0.718 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0012 | 0.0504 | 0.0768 |
Toxoplasma gondii | hypothetical protein | 0.0028 | 0.1412 | 0.0956 |
Toxoplasma gondii | cyclin dependent kinase binding protein | 0.0028 | 0.1412 | 0.0956 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0012 | 0.0504 | 0.0563 |
Echinococcus granulosus | cyclin t1 | 0.0028 | 0.1412 | 0.1566 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0028 | 0.1412 | 0.2181 |
Trypanosoma cruzi | cyclin, putative | 0.0117 | 0.6436 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0117 | 0.6436 | 1 |
Echinococcus multilocularis | cyclins | 0.0117 | 0.6436 | 0.7169 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0028 | 0.1412 | 0.2181 |
Trypanosoma cruzi | cyclin 9, putative | 0.0028 | 0.1412 | 0.1531 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.0028 | 0.1412 | 0.1531 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0117 | 0.6436 | 1 |
Schistosoma mansoni | cyclin B | 0.0117 | 0.6436 | 0.733 |
Schistosoma mansoni | cyclin G2 | 0.0028 | 0.1412 | 0.1599 |
Plasmodium vivax | cyclin homologue, putative | 0.0028 | 0.1412 | 0.0956 |
Trichomonas vaginalis | cyclin B, putative | 0.0117 | 0.6436 | 0.585 |
Entamoeba histolytica | cyclin, domain containing protein | 0.0028 | 0.1412 | 0.1531 |
Echinococcus multilocularis | cyclin B | 0.0117 | 0.6436 | 0.7169 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.0158 | 0.8777 | 1 |
Brugia malayi | cyclin fold protein 1 variant b | 0.0028 | 0.1412 | 0.2181 |
Echinococcus granulosus | cyclin k | 0.0028 | 0.1412 | 0.1566 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.6436 | 1 |
Plasmodium vivax | cyclin dependent kinase binding protein, putative | 0.0028 | 0.1412 | 0.0956 |
Giardia lamblia | Hypothetical protein | 0.0028 | 0.1412 | 0.2194 |
Plasmodium falciparum | cyclin dependent kinase binding protein, putative | 0.0028 | 0.1412 | 0.0956 |
Toxoplasma gondii | hypothetical protein | 0.0089 | 0.4838 | 0.4564 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0162 | 0.8974 | 1 |
Giardia lamblia | Cyclin A | 0.0117 | 0.6436 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0117 | 0.6436 | 1 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0117 | 0.6436 | 1 |
Schistosoma mansoni | cyclins | 0.0117 | 0.6436 | 0.733 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.018 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0117 | 0.6436 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0028 | 0.1412 | 0.2181 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0117 | 0.6436 | 1 |
Echinococcus granulosus | cyclin | 0.0028 | 0.1412 | 0.1566 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.1412 | 0.1599 |
Echinococcus multilocularis | cyclins | 0.0117 | 0.6436 | 0.7169 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.018 | 1 | 1 |
Echinococcus multilocularis | cyclin | 0.0028 | 0.1412 | 0.1564 |
Trichomonas vaginalis | cyclins, putative | 0.0117 | 0.6436 | 0.585 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0028 | 0.1412 | 0.2181 |
Trichomonas vaginalis | cyclins, putative | 0.0117 | 0.6436 | 0.585 |
Echinococcus granulosus | cyclin G2 | 0.0028 | 0.1412 | 0.1566 |
Echinococcus multilocularis | cyclins | 0.0117 | 0.6436 | 0.7169 |
Echinococcus granulosus | cyclin A3 4 | 0.0028 | 0.1412 | 0.1566 |
Loa Loa (eye worm) | cyclin C | 0.0028 | 0.1412 | 0.2181 |
Giardia lamblia | Cyclin B-like protein | 0.0028 | 0.1412 | 0.2194 |
Schistosoma mansoni | cyclin G | 0.0028 | 0.1412 | 0.1599 |
Trichomonas vaginalis | cyclin B, putative | 0.0117 | 0.6436 | 0.585 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0.1412 | 0.0956 |
Echinococcus granulosus | Cyclin L1 | 0.0028 | 0.1412 | 0.1566 |
Onchocerca volvulus | Cyclin L homolog | 0.0028 | 0.1412 | 0.1531 |
Loa Loa (eye worm) | cyclin fold protein 1 variant b | 0.0028 | 0.1412 | 0.2181 |
Brugia malayi | hypothetical protein | 0.0028 | 0.1412 | 0.2181 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0012 | 0.0504 | 0.0768 |
Echinococcus multilocularis | cyclin G2 | 0.0028 | 0.1412 | 0.1564 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0117 | 0.6436 | 1 |
Echinococcus multilocularis | oligomeric golgi complex subunit 3 | 0.0028 | 0.1412 | 0.1564 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0012 | 0.0504 | 0.0552 |
Schistosoma mansoni | g1/s-specific cyclin C | 0.0028 | 0.1412 | 0.1599 |
Toxoplasma gondii | cyclin 4, putative | 0.0028 | 0.1412 | 0.0956 |
Echinococcus multilocularis | cyclin t1 | 0.0028 | 0.1412 | 0.1564 |
Entamoeba histolytica | cyclin, putative | 0.0117 | 0.6436 | 1 |
Trypanosoma brucei | cyclin dependent kinase-binding protein, putative | 0.0028 | 0.1412 | 0.1531 |
Echinococcus granulosus | cyclin y | 0.0028 | 0.1412 | 0.1566 |
Echinococcus granulosus | cyclin B3 1 | 0.0117 | 0.6436 | 0.718 |
Onchocerca volvulus | Protein CNPPD1 homolog | 0.0028 | 0.1412 | 0.1531 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0117 | 0.6436 | 1 |
Echinococcus multilocularis | cyclin b3 | 0.0117 | 0.6436 | 0.7169 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0012 | 0.0504 | 0.0551 |
Echinococcus granulosus | oligomeric golgi complex subunit 3 | 0.0028 | 0.1412 | 0.1566 |
Echinococcus multilocularis | cdk5 and abl1 enzyme substrate 1 | 0.0028 | 0.1412 | 0.1564 |
Echinococcus multilocularis | cyclin y | 0.0028 | 0.1412 | 0.1564 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.1412 | 0.2181 |
Echinococcus granulosus | cyclins | 0.0117 | 0.6436 | 0.718 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0117 | 0.6436 | 1 |
Echinococcus multilocularis | cyclin G2 | 0.0028 | 0.1412 | 0.1564 |
Giardia lamblia | Hypothetical protein | 0.0028 | 0.1412 | 0.2194 |
Echinococcus multilocularis | cyclin k | 0.0028 | 0.1412 | 0.1564 |
Echinococcus granulosus | cyclins | 0.0117 | 0.6436 | 0.718 |
Plasmodium falciparum | cyclin | 0.0117 | 0.6436 | 0.6247 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0161 | 0.896 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0117 | 0.6436 | 0.585 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.018 | 1 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0028 | 0.1412 | 0.2181 |
Echinococcus multilocularis | cyclins | 0.0117 | 0.6436 | 0.7169 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0028 | 0.1412 | 0.2181 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.018 | 1 | 1 |
Trypanosoma brucei | cyclin 3 | 0.0028 | 0.1412 | 0.1531 |
Entamoeba histolytica | hypothetical protein | 0.0028 | 0.1412 | 0.1531 |
Entamoeba histolytica | cyclin, domain containing protein | 0.0028 | 0.1412 | 0.1531 |
Trichomonas vaginalis | cyclins, putative | 0.0117 | 0.6436 | 0.585 |
Echinococcus granulosus | cdk5 and abl1 enzyme substrate 1 | 0.0028 | 0.1412 | 0.1566 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.