Detailed information for compound 874436

Basic information

Technical information
  • TDR Targets ID: 874436
  • Name: 2-[[1-(cyclopropanecarbonyl)-2-methyl-2,3-dih ydroindol-5-yl]sulfonyl-methylamino]-N-(2-met hylphenyl)acetamide
  • MW: 441.543 | Formula: C23H27N3O4S
  • H donors: 1 H acceptors: 4 LogP: 2.62 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(CN(S(=O)(=O)c1ccc2c(c1)CC(N2C(=O)C1CC1)C)C)Nc1ccccc1C
  • InChi: 1S/C23H27N3O4S/c1-15-6-4-5-7-20(15)24-22(27)14-25(3)31(29,30)19-10-11-21-18(13-19)12-16(2)26(21)23(28)17-8-9-17/h4-7,10-11,13,16-17H,8-9,12,14H2,1-3H3,(H,24,27)
  • InChiKey: VKCDQMVKWXUWQJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[[1-(cyclopropanecarbonyl)-2-methyl-indolin-5-yl]sulfonyl-methyl-amino]-N-(2-methylphenyl)acetamide
  • 2-[[1-(cyclopropyl-oxomethyl)-2-methyl-5-indolinyl]sulfonyl-methylamino]-N-(2-methylphenyl)acetamide
  • 2-[(1-cyclopropylcarbonyl-2-methyl-2,3-dihydroindol-5-yl)sulfonyl-methyl-amino]-N-(2-methylphenyl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis dnaJ subfamily C 6 0.0065 0.0126 0.0125
Schistosoma mansoni alpha-glucosidase 0.0291 0.079 0.0887
Loa Loa (eye worm) transcription factor SMAD2 0.0771 0.2199 0.2495
Onchocerca volvulus 0.0093 0.0207 0.0948
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0142 0.0351 0.035
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0142 0.0351 0.035
Brugia malayi hypothetical protein 0.0065 0.0127 0.0144
Echinococcus multilocularis mothers against decapentaplegic 2 0.0023 0.0004 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0109 0.0362
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0122 0.0293 0.0329
Onchocerca volvulus 0.0097 0.0221 0.1011
Trypanosoma cruzi C-14 sterol reductase, putative 0.0094 0.0211 0.0448
Echinococcus granulosus glycine receptor subunit alpha 1 0.0142 0.0351 0.0393
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0013 0.0053
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0198 0.0518 0.0581
Schistosoma mansoni jumonji/arid domain-containing protein 0.0127 0.0308 0.0345
Onchocerca volvulus 0.0097 0.0221 0.1011
Chlamydia trachomatis hypothetical protein 0.0038 0.0047 0.1524
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0042 0.0059 0.1819
Schistosoma mansoni hypothetical protein 0.0052 0.0086 0.0096
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0122 0.0463
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0543 0.1528 0.301
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0602 0.1702 0.6631
Loa Loa (eye worm) serotonin transporter b 0.0304 0.0827 0.0939
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0155 0.0543
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0437 0.1217 0.1216
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0116 0.0276 0.1063
Leishmania major ion transport protein-like protein 0.0097 0.0221 0.0496
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0298 0.0809 0.4575
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0067
Echinococcus multilocularis JmjC domain containing protein 4 0.0033 0.0031 0.003
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Loa Loa (eye worm) hypothetical protein 0.0085 0.0184 0.0209
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0055 0.0096 0.0182
Echinococcus multilocularis rhodopsin orphan GPCR 0.0437 0.1217 0.1216
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0142 0.0351 0.0398
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0142 0.0351 0.0398
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0104 0.0212
Leishmania major GTP-binding protein, putative 0.0042 0.0059 0.0128
Mycobacterium ulcerans monoamine oxidase 0.0042 0.0059 0.0218
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0142 0.0351 0.0393
Echinococcus multilocularis L aminoadipate semialdehyde 0.0093 0.0207 0.0206
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0055 0.0096 0.0182
Toxoplasma gondii hypothetical protein 0.0052 0.0086 0.1691
Brugia malayi Cation transporter family protein 0.0142 0.0351 0.0398
Entamoeba histolytica hypothetical protein 0.0078 0.0164 0.0934
Echinococcus granulosus glycine receptor subunit alpha 1 0.0142 0.0351 0.0393
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0103 0.0237 0.8569
Schistosoma mansoni loxhd1 0.004 0.0052 0.0058
Toxoplasma gondii exonuclease III APE 0.0103 0.0237 0.5094
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0103 0.0237 0.0461
Onchocerca volvulus 0.0142 0.0351 0.1617
Onchocerca volvulus 0.0437 0.1217 0.5653
Mycobacterium tuberculosis Probable lipase LipE 0.0085 0.0184 0.0357
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0065 0.0127 0.0126
Brugia malayi MH2 domain containing protein 0.0053 0.0089 0.0101
Entamoeba histolytica pyruvate kinase, putative 0.0073 0.015 0.0852
Toxoplasma gondii hypothetical protein 0.0038 0.0047 0.081
Loa Loa (eye worm) hypothetical protein 0.0095 0.0215 0.0244
Mycobacterium tuberculosis Conserved protein 0.0085 0.0184 0.0357
Brugia malayi AKH receptor 0.0437 0.1217 0.1381
Schistosoma mansoni rab6-interacting 0.004 0.0052 0.0058
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0085 0.0184 0.0206
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0088 0.0098
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0052 0.0086 0.0098
Brugia malayi Cell death protein 3 precursor 0.0098 0.0223 0.0252
Brugia malayi hypoxia-induced factor 1 0.0148 0.037 0.042
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain F) NuoF (NADH-ubiquinone oxidoreductase chain F) 0.0161 0.0408 0.0799
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0159 0.0402 0.0451
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0092 0.0205 0.1127
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0025 0.0027
Schistosoma mansoni calcium-activated potassium channel 0.0097 0.0221 0.0247
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus granulosus geminin 0.1812 0.5256 0.591
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0004 0.0001
Brugia malayi Cation transporter family protein 0.0142 0.0351 0.0398
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0184 0.0206
Echinococcus multilocularis pyruvate kinase 0.0054 0.0093 0.0092
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0052 0.0086 0.0096
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0184 0.0206
Onchocerca volvulus Glucosylceramidase homolog 0.0202 0.0529 0.2446
Brugia malayi hypothetical protein 0.0097 0.0221 0.025
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0059 0.0067
Echinococcus granulosus apoptotic protease activating factor 1 0.0079 0.0166 0.0185
Schistosoma mansoni neurotransmitter gated ion channel 0.0076 0.0159 0.0178
Echinococcus granulosus microtubule associated protein 2 0.3051 0.8893 1
Echinococcus granulosus cytochrome P450 2K1 0.0055 0.0096 0.0106
Toxoplasma gondii thioredoxin reductase 0.0116 0.0275 0.5944
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.004 0.0053 0.0931
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0159 0.0402 0.0451
Echinococcus granulosus smad 0.0053 0.0089 0.0099
Brugia malayi jmjC domain containing protein 0.0127 0.0308 0.0349
Trichomonas vaginalis bromodomain-containing protein, putative 0.0094 0.0211 0.076
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0017 0.0003
Plasmodium vivax protease, putative 0.0038 0.0047 0.1362
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0033 0.0031 0.043
Schistosoma mansoni nAChR subunit 0.0065 0.0127 0.0141
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0016 0.001
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0052 0.0058
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0002 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0437 0.1217 0.1367
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0392 0.1085 0.6284
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0042 0.0059 0.0317
Mycobacterium tuberculosis Probable esterase LipL 0.0085 0.0184 0.0357
Onchocerca volvulus 0.0085 0.0184 0.0843
Loa Loa (eye worm) carboxylesterase 0.0159 0.0402 0.0456
Echinococcus granulosus rhodopsin orphan GPCR 0.0437 0.1217 0.1367
Loa Loa (eye worm) cytochrome P450 0.0055 0.0096 0.0108
Echinococcus granulosus rhodopsin orphan GPCR 0.0437 0.1217 0.1367
Echinococcus granulosus acetylcholinesterase 0.0941 0.2697 0.3032
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0025 0.0024
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.061 0.1725 1
Loa Loa (eye worm) Smad1 0.0053 0.0089 0.0101
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0437 0.1217 0.1367
Brugia malayi hypothetical protein 0.0027 0.0016 0.0018
Leishmania major hypothetical protein, conserved 0.0027 0.0016 0.0029
Echinococcus multilocularis potassium channel subfamily K 8 0.0097 0.0221 0.022
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.1643 0.4758 0.9384
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0085 0.0184 0.0209
Plasmodium vivax thioredoxin reductase, putative 0.0116 0.0275 1
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0053 0.0085
Loa Loa (eye worm) MH2 domain-containing protein 0.0023 0.0004 0.0004
Echinococcus granulosus neuropeptide receptor A26 0.0437 0.1217 0.1367
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0097 0.0221 0.025
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0097 0.0221 0.0469
Loa Loa (eye worm) MH2 domain-containing protein 0.0771 0.2199 0.2495
Loa Loa (eye worm) hypothetical protein 0.0941 0.2697 0.306
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0041 0.0055 0.0054
Onchocerca volvulus 0.0052 0.0086 0.0386
Schistosoma mansoni hypothetical protein 0.0615 0.174 0.1956
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Loa Loa (eye worm) hypothetical protein 0.0093 0.0207 0.0235
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0059 0.0066
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.004 0.0053 0.0192
Brugia malayi neuropeptide F receptor 0.0437 0.1217 0.1381
Schistosoma mansoni smad1 5 8 and 0.0053 0.0089 0.0099
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Brugia malayi acetyltransferase, GNAT family protein 0.0319 0.0872 0.099
Trypanosoma cruzi sterol C-24 reductase, putative 0.0094 0.0211 0.0448
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0055 0.0096 0.0182
Brugia malayi hypothetical protein 0.0097 0.0221 0.025
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.004 0.0053 0.1567
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0042 0.0059 0.0218
Loa Loa (eye worm) hypothetical protein 0.1515 0.4382 0.4972
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0116 0.0275 0.0536
Onchocerca volvulus 0.0159 0.0402 0.1855
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Echinococcus multilocularis nAChR subunit 0.0076 0.0159 0.0158
Trypanosoma cruzi ion transport protein, putative 0.0097 0.0221 0.0469
Trichomonas vaginalis D-aminoacylase, putative 0.0085 0.0184 0.0657
Loa Loa (eye worm) hypothetical protein 0.0056 0.0099 0.0112
Schistosoma mansoni nAChR subunit 0.0142 0.0351 0.0393
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.004 0.0053 0.1567
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0028 0.0017 0.0063
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0059 0.01
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0437 0.1217 0.1216
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0437 0.1217 0.1367
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0122 0.0234
Brugia malayi hypothetical protein 0.004 0.0052 0.0059
Loa Loa (eye worm) hypothetical protein 0.0159 0.0402 0.0456
Schistosoma mansoni hypothetical protein 0.0111 0.0262 0.0294
Schistosoma mansoni neuropeptide F-like receptor 0.0437 0.1217 0.1367
Echinococcus multilocularis pyruvate kinase 0.0083 0.0178 0.0178
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0161 0.0408 0.0899
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0142 0.0351 0.0393
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0038 0.0048 0.0211
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Loa Loa (eye worm) hypothetical protein 0.0077 0.0161 0.0183
Loa Loa (eye worm) hypothetical protein 0.0085 0.0184 0.0209
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.006 0.0111 0.042
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0067
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0059 0.01
Onchocerca volvulus 0.0437 0.1217 0.5653
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0092 0.0205 0.82
Brugia malayi larval opioid receptor 0.0437 0.1217 0.1381
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0161 0.3375
Echinococcus granulosus neuroligin 0.0159 0.0402 0.0451
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0142 0.0351 0.0398
Loa Loa (eye worm) acetyltransferase 0.0319 0.0872 0.099
Schistosoma mansoni polycystin 1-related 0.004 0.0052 0.0058
Onchocerca volvulus Huntingtin homolog 0.0137 0.0336 0.1549
Schistosoma mansoni microtubule-associated protein tau 0.3051 0.8893 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0052 0.0086 0.0098
Brugia malayi Probable ClpP-like protease 0.0077 0.0161 0.0183
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0264 0.071 0.1395
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0055 0.0096 0.0359
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.01 0.0229 0.083
Loa Loa (eye worm) intermediate filament protein 0.0116 0.0275 0.0311
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0529 0.2008
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0031 0.0035
Onchocerca volvulus 0.0065 0.0127 0.0574
Schistosoma mansoni BC026374 protein (S09 family) 0.0159 0.0402 0.0451
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0097 0.0221 0.025
Loa Loa (eye worm) solute carrier family 6 member 4 0.0304 0.0827 0.0939
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0092 0.0205 0.046
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0529 0.2008
Echinococcus granulosus twik family of potassium channels 0.0097 0.0221 0.0247
Echinococcus multilocularis smad 0.0053 0.0089 0.0088
Onchocerca volvulus 0.0437 0.1217 0.5653
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0076 0.0084
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0155 0.0543
Loa Loa (eye worm) hypothetical protein 0.0829 0.2369 0.2688
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0437 0.1217 0.1367
Echinococcus granulosus phd:f box containing protein 0.0033 0.0031 0.0033
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0038 0.0048 0.0087
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Brugia malayi MH2 domain containing protein 0.0771 0.2199 0.2495
Echinococcus granulosus RUN 0.004 0.0052 0.0058
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0437 0.1217 0.1367
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0142 0.0351 0.0398
Trypanosoma cruzi DNA repair protein, putative 0.0033 0.0031 0.0035
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0215 0.0241
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0076 0.0159 0.018
Mycobacterium ulcerans membrane protein ComEA 0.0036 0.0041 0.0144
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0055 0.0096 0.0183
Schistosoma mansoni hypothetical protein 0.1812 0.5256 0.591
Plasmodium vivax glutathione reductase, putative 0.0116 0.0275 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0065 0.0127 0.0144
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0215 0.0241
Plasmodium vivax potassium channel, putative 0.0097 0.0221 0.7935
Brugia malayi hypothetical protein 0.0079 0.0166 0.0188
Echinococcus granulosus flap endonuclease 1 0.0054 0.0094 0.0104
Echinococcus multilocularis pyruvate kinase 0.0054 0.0093 0.0092
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0012 0.0031
Echinococcus granulosus mothers against decapentaplegic 2 0.0023 0.0004 0.0003
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0142 0.0351 0.0393
Mycobacterium ulcerans beta-lactamase 0.0085 0.0184 0.0706
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0122 0.0136
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0042 0.0059 0.0066
Schistosoma mansoni hypothetical protein 0.0055 0.0096 0.0106
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.004 0.0053 0.0094
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0013 0.0052
Trypanosoma cruzi pyruvate kinase 2, putative 0.0105 0.0243 0.0522
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0085 0.0184 0.0206
Mycobacterium tuberculosis Conserved hypothetical protein 0.0036 0.0041 0.0073
Schistosoma mansoni sodium/solute symporter 0.0041 0.0055 0.006
Echinococcus granulosus JmjC domain containing protein 4 0.0033 0.0031 0.0033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1725 0.6704
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0186 0.048 0.0538
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.0109 0.0215
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Schistosoma mansoni Smad4 0.0053 0.0089 0.0099
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0116 0.0276 0.0309
Trichomonas vaginalis ap endonuclease, putative 0.0103 0.0237 0.0864
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Mycobacterium tuberculosis Probable reductase 0.0264 0.071 0.1395
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.01 0.0229 0.1051
Echinococcus granulosus pyruvate kinase 0.0105 0.0243 0.0273
Loa Loa (eye worm) hypothetical protein 0.0098 0.0223 0.0252
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0097 0.0221 0.025
Onchocerca volvulus 0.0437 0.1217 0.5653
Brugia malayi Dopamine receptor protein 2 0.0437 0.1217 0.1381
Echinococcus granulosus TGF beta signal transducer SmadC 0.0053 0.0089 0.0099
Brugia malayi MH1 domain containing protein 0.0053 0.0089 0.0101
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0122 0.0136
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0052 0.0086 0.0096
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0016 0.0159
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0002 0.0001
Echinococcus granulosus cpg binding protein 0.0092 0.0206 0.0231
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0055 0.0096 0.0182
Brugia malayi Thioredoxin reductase 0.0116 0.0275 0.0312
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Loa Loa (eye worm) hypothetical protein 0.0076 0.0159 0.018
Mycobacterium ulcerans lipase LipD 0.0085 0.0184 0.0706
Schistosoma mansoni glutamate receptor NMDA 0.0023 0.0002 0.0001
Toxoplasma gondii pyruvate kinase PyKII 0.0054 0.0093 0.1846
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0092 0.0205 0.0442
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0052 0.0086 0.0096
Echinococcus granulosus neuropeptide receptor 0.0437 0.1217 0.1367
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0437 0.1217 0.1216
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0161 0.018
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.004 0.0053 0.1753
Schistosoma mansoni amine GPCR 0.0437 0.1217 0.1367
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0004
Echinococcus granulosus glycine receptor subunit alpha 1 0.0142 0.0351 0.0393
Echinococcus granulosus neuropeptides capa receptor 0.0437 0.1217 0.1367
Schistosoma mansoni biogenic amine receptor 0.0437 0.1217 0.1367
Loa Loa (eye worm) hypothetical protein 0.0059 0.0109 0.0124
Echinococcus multilocularis 0.0055 0.0096 0.0095
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1725 0.6704
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.0109 0.0122
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0097 0.0221 0.025
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0038 0.0048 0.0172
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0437 0.1217 0.5653
Echinococcus granulosus SAM and MBT domain containing protein 0.0052 0.0088 0.0098
Brugia malayi hypothetical protein 0.0437 0.1217 0.1381
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1725 0.6704
Loa Loa (eye worm) acetylcholinesterase 1 0.0941 0.2697 0.306
Trichomonas vaginalis ap endonuclease, putative 0.0103 0.0237 0.0864
Brugia malayi hypothetical protein 0.0065 0.0127 0.0144
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1725 0.6704
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0122 0.0463
Plasmodium falciparum importin beta, putative 0.0058 0.0104 0.3513
Echinococcus multilocularis sex peptide receptor 0.0437 0.1217 0.1216
Echinococcus granulosus sodium:glucose cotransporter 2 0.0041 0.0055 0.006
Loa Loa (eye worm) TWK-28 protein 0.0097 0.0221 0.025
Schistosoma mansoni hypothetical protein 0.1812 0.5256 0.591
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0042 0.0059 0.1819
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0065 0.0127 0.0144
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0602 0.1702 0.6631
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0053 0.0089 0.0088
Brugia malayi MH2 domain containing protein 0.0053 0.0089 0.0101
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0198 0.0518 0.0587
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0031 0.0035
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.004 0.0053 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0085 0.0184 0.0386
Leishmania major importin beta-1 subunit, putative 0.0047 0.0072 0.0157
Entamoeba histolytica hypothetical protein 0.0078 0.0164 0.0934
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Onchocerca volvulus 0.0035 0.0039 0.0166
Echinococcus granulosus dro:myosuppressin receptor 0.0437 0.1217 0.1367
Giardia lamblia Pyruvate kinase 0.0054 0.0093 0.0242
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0055 0.0096 0.0182
Mycobacterium ulcerans pyruvate kinase 0.0105 0.0243 0.0937
Echinococcus multilocularis jumonji domain containing 1A 0.0033 0.0031 0.003
Schistosoma mansoni biogenic amine receptor 0.0437 0.1217 0.1367
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0088 0.0098
Echinococcus multilocularis thioredoxin glutathione reductase 0.0117 0.0279 0.0278
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0055 0.0096 0.0359
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Brugia malayi Carboxylesterase family protein 0.0159 0.0402 0.0456
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.0109 0.0243
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Trypanosoma brucei cytochrome P450, putative 0.009 0.0201 0.0433
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0048 0.0075 0.1434
Trichomonas vaginalis glutaminase, putative 0.0896 0.2565 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0053 0.0089 0.0101
Echinococcus multilocularis protoporphyrinogen oxidase 0.0042 0.0059 0.0058
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0097 0.0221 0.0469
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0055 0.0096 0.0359
Loa Loa (eye worm) hypothetical protein 0.0097 0.0219 0.0249
Loa Loa (eye worm) hypothetical protein 0.0245 0.0655 0.0743
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0097 0.0221 0.025
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0055 0.0096 0.0182
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1515 0.4382 0.4972
Loa Loa (eye worm) pyruvate kinase 0.0105 0.0243 0.0276
Echinococcus granulosus dnaJ subfamily C 6 0.0065 0.0126 0.0141
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Mycobacterium leprae Conserved hypothetical protein 0.0623 0.1765 1
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0065 0.0127 0.0141
Brugia malayi mbt repeat family protein 0.0052 0.0088 0.01
Mycobacterium ulcerans integral membrane protein 0.0038 0.0047 0.0171
Echinococcus multilocularis SAM and MBT domain containing protein 0.0052 0.0088 0.0087
Trypanosoma brucei C-14 sterol reductase, putative 0.0094 0.0211 0.0457
Echinococcus granulosus hypothetical protein 0.0437 0.1217 0.1367
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0083 0.0082
Leishmania major hypothetical protein, conserved 0.0097 0.0221 0.0496
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1749 0.507 1
Echinococcus granulosus lamin dm0 0.0116 0.0275 0.0308
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0052 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0019
Plasmodium vivax amine transporter, putative 0.0052 0.0086 0.2845
Echinococcus granulosus CAAX prenyl protease 2 0.0186 0.048 0.0538
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0142 0.0351 0.0398
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0092 0.0205 0.0232
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0012 0.0045
Brugia malayi MH2 domain containing protein 0.0023 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0337 0.0924 0.1039
Schistosoma mansoni sodium/chloride dependent transporter 0.0052 0.0086 0.0096
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0016 0.0159
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0346 0.0951 0.1068
Echinococcus granulosus mothers against decapentaplegic 5 0.0053 0.0089 0.0099
Toxoplasma gondii histone lysine-specific demethylase 0.0042 0.0059 0.1081
Brugia malayi MH1 domain containing protein 0.0053 0.0089 0.0101
Plasmodium falciparum pyruvate kinase 2 0.0054 0.0093 0.3106
Echinococcus multilocularis serotonin receptor 0.1559 0.451 0.451
Onchocerca volvulus 0.0089 0.0197 0.0901
Echinococcus multilocularis neuropeptides capa receptor 0.0437 0.1217 0.1216
Brugia malayi follicle stimulating hormone receptor 0.0675 0.1917 0.2175
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Loa Loa (eye worm) hypothetical protein 0.0054 0.0093 0.0105
Loa Loa (eye worm) cytochrome P450 family protein 0.0113 0.0266 0.0302
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0804 0.2295 0.2294
Schistosoma mansoni phosphatidylserine receptor 0.0033 0.0031 0.0033
Brugia malayi hypothetical protein 0.0437 0.1217 0.1381
Onchocerca volvulus 0.033 0.0903 0.4189
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0052 0.0051
Brugia malayi Tachykinin-like peptides receptor 99D 0.0437 0.1217 0.1381
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0042 0.0059 0.0066
Entamoeba histolytica acyl-CoA synthetase, putative 0.0034 0.0036 0.019
Echinococcus granulosus biogenic amine 5HT receptor 0.0804 0.2295 0.258
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0122 0.0136
Schistosoma mansoni jumonji domain containing protein 0.0122 0.0293 0.0329
Loa Loa (eye worm) hypothetical protein 0.0159 0.0402 0.0456
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0103 0.0237 0.8569
Echinococcus granulosus jumonji domain containing 1A 0.0033 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.1 0.2871 0.3258
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0518 0.0581
Echinococcus multilocularis musashi 0.0116 0.0275 0.0274
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0065 0.0127 0.0144
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0097 0.0221 0.1261
Schistosoma mansoni calcium-activated potassium channel 0.2172 0.631 0.7096
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0142 0.0351 0.0398
Echinococcus multilocularis 0.0042 0.0059 0.0058
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0076 0.0159 0.0178
Brugia malayi hypothetical protein 0.0042 0.0059 0.0067
Echinococcus multilocularis lysine specific demethylase 6a 0.0033 0.0031 0.003
Brugia malayi RNA, U transporter 1 0.0164 0.0416 0.0472
Brugia malayi Dopamine receptor protein 1 0.3024 0.8813 1
Loa Loa (eye worm) pyruvate kinase 0.0105 0.0243 0.0276
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.0161 0.0408 0.1536
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0529 0.2008
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Schistosoma mansoni alpha glucosidase 0.0075 0.0155 0.0174
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0052 0.0086 0.0098
Loa Loa (eye worm) NADH-ubiquinone oxidoreductase 51 kDa subunit 0.0161 0.0408 0.0463
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0097 0.0221 0.025
Brugia malayi hypothetical protein 0.0078 0.0164 0.0186
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0155 0.0543
Echinococcus multilocularis serotonin transporter 0.0304 0.0827 0.0826
Mycobacterium ulcerans NADH dehydrogenase I subunit F 0.0161 0.0408 0.158
Onchocerca volvulus 0.0196 0.0509 0.2357
Schistosoma mansoni calcium-activated potassium channel 0.1829 0.5305 0.5965
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0055 0.0096 0.0182
Loa Loa (eye worm) hypothetical protein 0.0029 0.002 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0055 0.0096 0.0182
Trichomonas vaginalis set domain proteins, putative 0.0754 0.215 0.8371
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0083 0.0452
Echinococcus multilocularis nAChR subunit 0.0142 0.0351 0.035
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0103 0.0237 0.1358
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Schistosoma mansoni amine GPCR 0.0794 0.2266 0.2548
Mycobacterium tuberculosis Probable hydrolase 0.0085 0.0184 0.0357
Echinococcus multilocularis microtubule associated protein 2 0.3051 0.8893 0.8892
Echinococcus granulosus neuropeptides capa receptor 0.0437 0.1217 0.1367
Echinococcus multilocularis dnaJ subfamily B 0.1246 0.3592 0.3591
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0078 0.0163 0.0162
Leishmania major acetoin dehydrogenase e3 component-like protein 0.004 0.0053 0.0113
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0437 0.1217 0.1216
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0067
Loa Loa (eye worm) melatonin receptor type 1A 0.0437 0.1217 0.1381
Echinococcus multilocularis neuropeptide Y receptor 0.0437 0.1217 0.1216
Brugia malayi glutaminase DH11.1 0.0896 0.2565 0.291
Loa Loa (eye worm) mbt repeat family protein 0.0052 0.0088 0.01
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0142 0.0351 0.035
Trichomonas vaginalis glucosylceramidase, putative 0.0213 0.0561 0.2133
Onchocerca volvulus 0.0437 0.1217 0.5653
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0097 0.0221 0.025
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0338 0.0928 0.1053
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0059 0.0109 0.0124
Loa Loa (eye worm) hypothetical protein 0.0161 0.0407 0.0462
Echinococcus granulosus sodium and chloride dependent glycine 0.0052 0.0086 0.0096
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0055 0.0096 0.0359
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0219 0.0245
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0142 0.0351 0.0398
Plasmodium vivax JmjC domain containing protein 0.0033 0.0031 0.0723
Schistosoma mansoni cpg binding protein 0.0087 0.0192 0.0215
Loa Loa (eye worm) hypothetical protein 0.0192 0.05 0.0567
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0085 0.0184 0.0706
Loa Loa (eye worm) hypothetical protein 0.0159 0.0402 0.0456
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0142 0.0351 0.0398
Loa Loa (eye worm) hypothetical protein 0.0774 0.2208 0.2505
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0052 0.0086 0.0096
Trichomonas vaginalis pyruvate kinase, putative 0.0105 0.0243 0.0889
Loa Loa (eye worm) histone methyltransferase 0.0031 0.0025 0.0028
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0437 0.1217 0.1367
Schistosoma mansoni protein phosphatase 2C 0.0033 0.0031 0.0033
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0155 0.0543
Brugia malayi neuropeptide F receptor 0.0437 0.1217 0.1381
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0221 0.0247
Echinococcus multilocularis neuropeptide FF receptor 2 0.0437 0.1217 0.1216
Loa Loa (eye worm) hypothetical protein 0.0159 0.0402 0.0456
Mycobacterium ulcerans glutaminase 0.0896 0.2565 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0029 0.0022 0.0024
Echinococcus granulosus tm gpcr rhodopsin 0.0437 0.1217 0.1367
Loa Loa (eye worm) pyruvate kinase-PB 0.0073 0.015 0.017
Leishmania major potassium channel subunit-like protein 0.0097 0.0221 0.0496
Trichomonas vaginalis glucosylceramidase, putative 0.0308 0.084 0.3229
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0083 0.0157
Trypanosoma brucei pyruvate kinase 1 0.0105 0.0243 0.0531
Onchocerca volvulus 0.0142 0.0351 0.1617
Schistosoma mansoni Lamin B receptor (ERG24) 0.0094 0.0211 0.0236
Onchocerca volvulus 0.0142 0.0351 0.1617
Trypanosoma brucei glycosyl hydrolase-like protein 0.0028 0.0017 0.0013
Schistosoma mansoni pyruvate kinase 0.0105 0.0243 0.0273
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0052 0.0086 0.0096
Loa Loa (eye worm) hypothetical protein 0.0079 0.0166 0.0188
Trypanosoma cruzi hypothetical protein, conserved 0.0097 0.0221 0.0469
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0017 0.0003
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Schistosoma mansoni nAChR subunit 0.0142 0.0351 0.0393
Schistosoma mansoni nAChR subunit 0.0142 0.0351 0.0393
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0142 0.0351 0.0393
Onchocerca volvulus 0.0437 0.1217 0.5653
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0055 0.0096 0.0182
Trichomonas vaginalis penicillin-binding protein, putative 0.0085 0.0184 0.0657
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0024 0.0027
Schistosoma mansoni hypothetical protein 0.2172 0.631 0.7096
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0085 0.0184 0.0357
Plasmodium vivax hypothetical protein, conserved 0.0085 0.0184 0.6562
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0052 0.0086 0.3182
Echinococcus multilocularis rhodopsin orphan GPCR 0.0437 0.1217 0.1216
Echinococcus multilocularis BC026374 protein (S09 family) 0.0159 0.0402 0.0401
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0055 0.0096 0.0359
Schistosoma mansoni hypothetical protein 0.0065 0.0126 0.0141
Echinococcus granulosus histone lysine methyltransferase setb 0.0097 0.0219 0.0245
Loa Loa (eye worm) MBCTL1 0.0059 0.0109 0.0124
Schistosoma mansoni sodium/chloride dependent transporter 0.0304 0.0827 0.0929
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase I subunit F 0.0161 0.0408 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0097 0.0221 0.0799
Onchocerca volvulus 0.0159 0.0402 0.1855
Brugia malayi jmjC domain containing protein 0.0033 0.0031 0.0035
Entamoeba histolytica CAAX amino terminal protease family 0.0038 0.0047 0.0255
Echinococcus multilocularis lamin dm0 0.0116 0.0275 0.0274
Onchocerca volvulus 0.0437 0.1217 0.5653
Trypanosoma cruzi hypothetical protein, conserved 0.0085 0.0184 0.0386
Plasmodium vivax importin-beta 2, putative 0.0058 0.0104 0.3513
Echinococcus multilocularis mothers against decapentaplegic 6 0.0023 0.0004 0.0003
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0052 0.0086 0.0096
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0013 0.0052
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0085 0.0184 0.0357
Toxoplasma gondii hypothetical protein 0.0052 0.0086 0.1691
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0028 0.0017 0.0079
Plasmodium vivax pyruvate kinase 2, putative 0.0054 0.0093 0.3106
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0161 0.018
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0042 0.0059 0.1819
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0059 0.1081
Schistosoma mansoni alpha-glucosidase 0.0291 0.079 0.0887
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Schistosoma mansoni nAChR subunit 0.0142 0.0351 0.0393
Brugia malayi hypothetical protein 0.0437 0.1217 0.1381
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0437 0.1217 0.1367
Toxoplasma gondii histone lysine methyltransferase SET1 0.0177 0.0455 1
Echinococcus multilocularis para nitrobenzyl esterase 0.0159 0.0402 0.0401
Echinococcus granulosus allatostatin A receptor 0.0437 0.1217 0.1367
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0097 0.0221 0.025
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.004 0.0053 0.0192
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0103 0.0237 0.0912
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0437 0.1217 0.1381
Echinococcus granulosus neuropeptide Y receptor 0.0437 0.1217 0.1367
Giardia lamblia DNA repair protein RAD52 0.0392 0.1085 0.6174
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Entamoeba histolytica hypothetical protein 0.0078 0.0164 0.0934
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0055 0.0096 0.0359
Schistosoma mansoni histamine h1 receptor 0.0437 0.1217 0.1367
Brugia malayi mothers against decapentaplegic homolog 3 0.0023 0.0004 0.0004
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0319 0.0872 0.0871
Echinococcus granulosus potassium channel subfamily K 8 0.0097 0.0221 0.0247
Brugia malayi Carboxylesterase family protein 0.0159 0.0402 0.0456
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0161 0.5678
Schistosoma mansoni neuropeptide f receptor 76f 0.0437 0.1217 0.1367
Brugia malayi Pre-SET motif family protein 0.0663 0.1882 0.2135
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0159 0.0402 0.0786
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0052 0.1542
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0053 0.0085
Loa Loa (eye worm) hypothetical protein 0.0076 0.0159 0.018
Onchocerca volvulus 0.0097 0.0221 0.1011
Schistosoma mansoni neurotransmitter gated ion channel 0.0065 0.0127 0.0141
Echinococcus multilocularis NADH dehydrogenase (ubiquinone) flavoprotein 1 0.0161 0.0408 0.0407
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0142 0.0351 0.035
Schistosoma mansoni hypothetical protein 0.004 0.0052 0.0058
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.01 0.0229 0.083
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0039 0.0139
Schistosoma mansoni smad1 5 8 and 0.0053 0.0089 0.0099
Brugia malayi Cation transporter family protein 0.0142 0.0351 0.0398
Echinococcus granulosus g-protein coupled receptor 0.0437 0.1217 0.1367
Onchocerca volvulus 0.0097 0.0219 0.1004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.004 0.0053 0.0085
Trypanosoma cruzi sterol C-24 reductase, putative 0.0094 0.0211 0.0448
Loa Loa (eye worm) hypothetical protein 0.0052 0.0086 0.0098
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.003 0.0022 0.0014
Brugia malayi Cytochrome P450 family protein 0.0055 0.0096 0.0108
Loa Loa (eye worm) hypothetical protein 0.0085 0.0184 0.0209
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0437 0.1217 0.1367
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0159 0.0402 0.0401
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1725 0.6704
Loa Loa (eye worm) hypothetical protein 0.037 0.1021 0.1158
Echinococcus multilocularis nmda type glutamate receptor 0.0053 0.0092 0.0091
Brugia malayi exodeoxyribonuclease III family protein 0.0103 0.0237 0.0269
Loa Loa (eye worm) carboxylesterase 0.0941 0.2697 0.306
Schistosoma mansoni acetylcholine receptor-related 0.0065 0.0127 0.0141
Loa Loa (eye worm) TWK-7 protein 0.0097 0.0221 0.025
Echinococcus multilocularis lamin 0.0116 0.0275 0.0274
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.017 0.0433 0.1634
Onchocerca volvulus 0.0437 0.1217 0.5653
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0059 0.0109 0.0121
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0116 0.0276 0.0537
Brugia malayi G protein-coupled receptor F59B2.13 0.0437 0.1217 0.1381
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0076 0.0159 0.0178
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0052 0.0086 0.0096
Chlamydia trachomatis glutamine binding protein 0.0038 0.0048 0.1537
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0159 0.0402 0.0451
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0053 0.0085
Loa Loa (eye worm) carboxylesterase 0.0159 0.0402 0.0456
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0437 0.1217 0.1367
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus granulosus mothers against decapentaplegic 6 0.0023 0.0004 0.0003
Onchocerca volvulus Cell death protein 3 homolog 0.0098 0.0223 0.102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0437 0.1217 0.1367
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.004 0.0053 0.0085
Loa Loa (eye worm) acetylcholine receptor protein 0.0065 0.0127 0.0144
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0226 0.0598 0.0671
Treponema pallidum exodeoxyribonuclease (exoA) 0.0103 0.0237 0.1317
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0104 0.0103
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0142 0.0351 0.0398
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0437 0.1217 0.1381
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0437 0.1217 0.1367
Loa Loa (eye worm) hypothetical protein 0.0915 0.2622 0.2976
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0052 0.0086 0.0096
Brugia malayi hypothetical protein 0.0437 0.1217 0.1381
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0097 0.0221 0.0428
Echinococcus granulosus importin subunit beta 1 0.0058 0.0104 0.0116
Echinococcus granulosus pyruvate kinase 0.0054 0.0093 0.0104
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Schistosoma mansoni adenoreceptor 0.0437 0.1217 0.1367
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0142 0.0351 0.0393
Echinococcus multilocularis G protein coupled receptor 139 0.0437 0.1217 0.1216
Schistosoma mansoni cytochrome P450 0.0055 0.0096 0.0106
Onchocerca volvulus 0.0085 0.0184 0.0843
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.0109 0.0224
Echinococcus granulosus tm gpcr rhodopsin 0.1456 0.4211 0.4734
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0219 0.0245
Onchocerca volvulus 0.0065 0.0127 0.0574
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0052 0.0088 0.0392
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0437 0.1217 0.1381
Echinococcus granulosus orexin receptor type 2 0.0437 0.1217 0.1367
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0192 0.05 0.2884
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0529 0.2008
Loa Loa (eye worm) hypothetical protein 0.0085 0.0184 0.0209
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0053 0.0089 0.0099
Mycobacterium ulcerans recombinase A 0.0106 0.0247 0.095
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0221 0.0247
Loa Loa (eye worm) thioredoxin reductase 0.0116 0.0275 0.0312
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0122 0.0293 0.0292
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0198 0.0518 0.0517
Echinococcus multilocularis twik family of potassium channels 0.0097 0.0221 0.022
Plasmodium falciparum thioredoxin reductase 0.004 0.0053 0.1567
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.0109 0.0339
Treponema pallidum hypothetical protein 0.0038 0.0047 0.0209
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0075 0.0155 0.0176
Treponema pallidum nitrogen fixation protein (rnfC) 0.0036 0.0041 0.0169
Schistosoma mansoni nAChR subunit 0.0065 0.0127 0.0141
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0097 0.0221 0.0247
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0097 0.0221 0.025
Leishmania major trypanothione reductase 0.0116 0.0275 0.0621
Loa Loa (eye worm) hypothetical protein 0.0114 0.0268 0.0304
Mycobacterium tuberculosis Possible oxidoreductase 0.0042 0.0059 0.011
Onchocerca volvulus 0.0437 0.1217 0.5653
Schistosoma mansoni ap endonuclease 0.0103 0.0237 0.0266
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0437 0.1217 0.1216
Trichomonas vaginalis flap endonuclease-1, putative 0.0054 0.0094 0.0301
Schistosoma mansoni phd/f-box containing protein 0.0033 0.0031 0.0033
Brugia malayi hypothetical protein 0.0065 0.0127 0.0144
Schistosoma mansoni amine oxidase 0.0042 0.0059 0.0066
Loa Loa (eye worm) nuclear factor I 0.0029 0.002 0.0023
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0072 0.0216
Brugia malayi Intermediate filament tail domain containing protein 0.0116 0.0275 0.0311
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0198 0.0518 0.0581
Onchocerca volvulus 0.0437 0.1217 0.5653
Leishmania major UDP-galactopyranose mutase 0.0042 0.0059 0.0128
Echinococcus granulosus Smad4 0.0053 0.0089 0.0099
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0033 0.0031 0.043
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0142 0.0351 0.0393
Echinococcus granulosus sex peptide receptor 0.0437 0.1217 0.1367
Echinococcus multilocularis high affinity choline transporter 1 0.037 0.1021 0.102
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0078 0.0163 0.0185
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0198 0.0518 0.0517
Schistosoma mansoni pyruvate kinase 0.0105 0.0243 0.0273
Trypanosoma brucei CAAX amino terminal protease, putative 0.0186 0.048 0.1071
Plasmodium falciparum potassium channel 0.0097 0.0221 0.7935
Onchocerca volvulus 0.0437 0.1217 0.5653
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus granulosus neuropeptide Y receptor 0.0437 0.1217 0.1367
Brugia malayi hypothetical protein 0.0052 0.0086 0.0098
Brugia malayi hypothetical protein 0.0159 0.0402 0.0456
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0189 0.049 0.055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0053 0.0085
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0001 0.0001
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0055 0.0096 0.0183
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0055 0.0096 0.0182
Loa Loa (eye worm) CXXC zinc finger family protein 0.0087 0.0192 0.0218
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0108 0.0251 0.0917
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Echinococcus multilocularis cpg binding protein 0.0092 0.0206 0.0205
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.003 0.0024 0.002
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0092 0.0205 0.0204
Trichomonas vaginalis glucosylceramidase, putative 0.0308 0.084 0.3229
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0023 0.0004 0.0002
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0054 0.0094 0.0207
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0053 0.0092 0.0091
Giardia lamblia Hypothetical protein 0.0097 0.0221 0.1003
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0104 0.2088
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0004
Plasmodium falciparum JmjC domain-containing protein, putative 0.0033 0.0031 0.0723
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus multilocularis GPCR, family 2 0.0052 0.0086 0.0085
Onchocerca volvulus 0.0437 0.1217 0.5653
Echinococcus granulosus NADH dehydrogenase ubiquinone flavoprotein 1 0.0161 0.0408 0.0458
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0294 0.0797 0.4504
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0437 0.1217 0.1216
Mycobacterium tuberculosis Conserved protein 0.0085 0.0184 0.0357
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1725 0.6704
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0097 0.0221 0.025
Schistosoma mansoni acetylcholine receptor subunit beta 0.0065 0.0127 0.0141
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Loa Loa (eye worm) hypothetical protein 0.0085 0.0184 0.0209
Brugia malayi Dopamine receptor 0.0437 0.1217 0.1381
Brugia malayi hypothetical protein 0.0437 0.1217 0.1381
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0052 0.0086 0.0085
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0142 0.0351 0.0398
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0055 0.0096 0.0182
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.061 0.1725 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0065 0.0127 0.0144
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0013 0.0008
Brugia malayi putative neuropeptide receptor NPR1 0.0437 0.1217 0.1381
Brugia malayi Carboxylesterase family protein 0.0941 0.2697 0.306
Brugia malayi Carboxylesterase family protein 0.0159 0.0402 0.0456
Trichomonas vaginalis esterase, putative 0.0085 0.0184 0.0657
Leishmania major hypothetical protein, conserved 0.0097 0.0221 0.0496
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0038 0.0045 0.005
Schistosoma mansoni importin beta-1 0.0058 0.0104 0.0116
Loa Loa (eye worm) hypothetical protein 0.0033 0.0031 0.0035
Schistosoma mansoni neuropeptide F-like receptor 0.0437 0.1217 0.1367
Echinococcus multilocularis CAAX prenyl protease 2 0.0186 0.048 0.0479
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0097 0.0221 0.0247
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0094 0.0211 0.4494
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0094 0.0211 0.076
Echinococcus multilocularis Smad4 0.0053 0.0089 0.0088
Plasmodium falciparum thioredoxin reductase 0.0116 0.0275 1
Echinococcus granulosus pyruvate kinase 0.0054 0.0093 0.0104
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0675 0.1917 0.2175
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0319 0.0872 0.098
Echinococcus multilocularis sodium and chloride dependent glycine 0.0052 0.0086 0.0085
Brugia malayi beta-lactamase family protein 0.0085 0.0184 0.0209
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0055 0.0096 0.0182
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0085 0.0184 0.0357
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0264 0.071 0.1395
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0161 0.0408 0.0899
Echinococcus granulosus intermediate filament protein 0.0116 0.0275 0.0308
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0067
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0052 0.0086 0.1691
Schistosoma mansoni myosin xvIII 0.0437 0.1217 0.1367
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0092 0.0205 0.0433
Brugia malayi jmjC domain containing protein 0.0033 0.0031 0.0035
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0142 0.0351 0.0398
Onchocerca volvulus 0.0437 0.1217 0.5653
Brugia malayi Serotonin receptor 0.0891 0.2551 0.2895
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0437 0.1217 0.1381
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0097 0.0221 0.025
Onchocerca volvulus 0.0095 0.0215 0.0986
Onchocerca volvulus 0.0754 0.215 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0163 0.0413 0.0469
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0052 0.0086 0.0085
Loa Loa (eye worm) LGC-31 protein 0.0142 0.0351 0.0398
Echinococcus granulosus single minded 2 0.0043 0.006 0.0066
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.017 0.0433 0.1634
Loa Loa (eye worm) GABA receptor subunit 0.0076 0.0159 0.018
Schistosoma mansoni amine GPCR 0.0437 0.1217 0.1367
Toxoplasma gondii NADPH-glutathione reductase 0.004 0.0053 0.0931
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Loa Loa (eye worm) G-protein coupled receptor 0.0437 0.1217 0.1381
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0023 0.0002 0.0001
Brugia malayi hypothetical protein 0.0065 0.0127 0.0144
Mycobacterium leprae Conserved hypothetical protein 0.0055 0.0096 0.0522
Trypanosoma brucei pyruvate kinase 1, putative 0.0105 0.0243 0.0531
Leishmania major calcium/potassium channel (CAKC), putative 0.0097 0.0221 0.0496
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1515 0.4382 1
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus granulosus lysine specific demethylase 6a 0.0033 0.0031 0.0033
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0437 0.1217 0.1367
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0097 0.0221 0.0469
Loa Loa (eye worm) hypothetical protein 0.0159 0.0402 0.0456
Loa Loa (eye worm) CYP4Cod1 0.009 0.0201 0.0228
Giardia lamblia Pyruvate kinase 0.0105 0.0243 0.114
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.004 0.0053 0.0094
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0161 0.0894
Entamoeba histolytica CAAX amino terminal protease family 0.0038 0.0047 0.0255
Plasmodium falciparum transporter, putative 0.0052 0.0086 0.2845
Leishmania major glycosyl hydrolase-like protein 0.0028 0.0017 0.0032
Brugia malayi Importin beta-1 subunit 0.0058 0.0104 0.0118
Mycobacterium ulcerans hypothetical protein 0.0038 0.0047 0.0171
Echinococcus multilocularis alkaline phosphatase 0.0346 0.0951 0.095
Echinococcus granulosus neuropeptide s receptor 0.0437 0.1217 0.1367
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0437 0.1217 0.1367
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0103 0.0237 0.0236
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0055 0.0096 0.0182
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0298 0.0809 0.1591
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.004 0.0053 0.0097
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0059 0.004
Echinococcus granulosus solute carrier family 5 0.0041 0.0055 0.006
Brugia malayi glutathione reductase 0.0116 0.0275 0.0312
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0142 0.0351 0.0398
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Schistosoma mansoni hypothetical protein 0.0437 0.1217 0.1367
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.0161 0.0408 0.0458
Echinococcus granulosus histone acetyltransferase MYST2 0.0059 0.0109 0.0121
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0116 0.0276 0.0275
Loa Loa (eye worm) MH1 domain-containing protein 0.0053 0.0089 0.0101
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0056 0.0099 0.011
Toxoplasma gondii ABC1 family protein 0.0085 0.0184 0.3901
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0083 0.0092
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0155 0.0543
Brugia malayi hypothetical protein 0.004 0.0052 0.0059
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.004 0.0053 0.0094
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0122 0.0271
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0116 0.0276 0.0623
Schistosoma mansoni neuropeptide receptor 0.0437 0.1217 0.1367
Onchocerca volvulus NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial homolog 0.0086 0.0189 0.0863
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0004
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0142 0.0351 0.0393
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0065 0.0127 0.0144
Brugia malayi Cytochrome P450 family protein 0.009 0.0201 0.0228
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0055 0.0096 0.0359
Loa Loa (eye worm) cytochrome P450 family protein 0.009 0.0201 0.0228
Echinococcus granulosus lysosomal alpha glucosidase 0.0338 0.0928 0.1043
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Brugia malayi Glycosyl hydrolases family 31 protein 0.0028 0.0017 0.0019
Echinococcus granulosus serotonin transporter 0.0304 0.0827 0.0929
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0054 0.0094 0.1854
Echinococcus granulosus sodium and chloride dependent glycine 0.0052 0.0086 0.0096
Entamoeba histolytica Ran family GTPase 0.0042 0.0059 0.0325
Echinococcus multilocularis sodium and chloride dependent glycine 0.0052 0.0086 0.0085
Brugia malayi mbt repeat family protein 0.0052 0.0088 0.01
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0059 0.1819
Plasmodium vivax flap endonuclease 1, putative 0.0054 0.0094 0.3119
Schistosoma mansoni nAChR subunit 0.0142 0.0351 0.0393
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0346 0.0951 0.095
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0142 0.0351 0.035
Echinococcus multilocularis small conductance calcium activated potassium 0.2172 0.631 0.631
Echinococcus granulosus potassium channel subfamily K 0.0097 0.0221 0.0247
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0142 0.0351 0.0398
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0221 0.0247
Echinococcus multilocularis lamin b receptor 0.0094 0.0211 0.021
Brugia malayi cytochrome P450 0.0055 0.0096 0.0108
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0004 0.0004
Schistosoma mansoni inositol transporter 0.0041 0.0055 0.006
Toxoplasma gondii ion channel protein 0.0097 0.0221 0.4717
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0308 0.084 0.0953
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.0109 0.0108
Trypanosoma cruzi pyruvate kinase 2, putative 0.0105 0.0243 0.0522
Leishmania major hypothetical protein, conserved 0.0085 0.0184 0.0414
Onchocerca volvulus 0.0304 0.0827 0.3837
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0941 0.2697 0.306
Onchocerca volvulus 0.0437 0.1217 0.5653
Echinococcus granulosus dnaJ subfamily B 0.1246 0.3592 0.4038
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0052 0.0051
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0159 0.0402 0.1509
Trichomonas vaginalis spcc417.12 protein, putative 0.0159 0.0402 0.1509
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0053 0.0085
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0161 0.016
Brugia malayi Serotonin receptor 0.0437 0.1217 0.1381
Brugia malayi hypothetical protein 0.0437 0.1217 0.1381
Onchocerca volvulus 0.004 0.0052 0.0226
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0097 0.0221 0.025
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0016 0.0095
Echinococcus multilocularis pyruvate kinase 0.0105 0.0243 0.0243
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0122 0.2495
Echinococcus multilocularis dro:myosuppressin receptor 0.0437 0.1217 0.1216
Echinococcus multilocularis RUN 0.004 0.0052 0.0051
Schistosoma mansoni alkaline phosphatase 0.0346 0.0951 0.1068
Echinococcus multilocularis lysosomal alpha glucosidase 0.0338 0.0928 0.0927
Echinococcus granulosus twik family of potassium channels 0.0097 0.0221 0.0247
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0155 0.0543
Onchocerca volvulus 0.0097 0.0221 0.1011
Loa Loa (eye worm) ACC-1 protein 0.0142 0.0351 0.0398
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0002 0.0001
Brugia malayi Sodium:solute symporter family protein 0.0041 0.0055 0.0062
Loa Loa (eye worm) hypothetical protein 0.0304 0.0827 0.0939
Loa Loa (eye worm) hypothetical protein 0.0095 0.0215 0.0244
Schistosoma mansoni hypothetical protein 0.0052 0.0086 0.0096
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0221 0.0247
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0437 0.1217 0.1381
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Echinococcus granulosus neuropeptide FF receptor 2 0.0437 0.1217 0.1367
Brugia malayi Cytochrome P450 family protein 0.009 0.0201 0.0228
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0142 0.0351 0.0393
Echinococcus multilocularis calcium activated potassium channel variant 0.0097 0.0221 0.022
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0116 0.0276 0.1063
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0038 0.0048 0.1537
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.037 0.042
Trichomonas vaginalis glucosylceramidase, putative 0.0308 0.084 0.3229
Schistosoma mansoni alkaline phosphatase 0.0346 0.0951 0.1068
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0065 0.0127 0.0144
Echinococcus multilocularis neuropeptide s receptor 0.0437 0.1217 0.1216
Schistosoma mansoni lipoxygenase 0.004 0.0052 0.0058
Brugia malayi putative neuropeptide receptor 0.0437 0.1217 0.1381
Echinococcus granulosus nmda type glutamate receptor 0.0053 0.0092 0.0102
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0142 0.0351 0.0393
Schistosoma mansoni neurotransmitter gated ion channel 0.0065 0.0127 0.0141
Toxoplasma gondii CAAX amino terminal protease family protein 0.0038 0.0047 0.081
Echinococcus multilocularis carboxylesterase 5A 0.0941 0.2697 0.2696
Schistosoma mansoni inositol transporter 0.0041 0.0055 0.006
Onchocerca volvulus Pyruvate kinase homolog 0.0105 0.0243 0.1118
Echinococcus multilocularis geminin 0.1812 0.5256 0.5255
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Schistosoma mansoni biogenic amine (5HT) receptor 0.1559 0.451 0.5071
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0023 0.0002 0.0001
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0437 0.1217 0.1381
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0065 0.0127 0.0126
Schistosoma mansoni ran 0.0042 0.0059 0.0066
Echinococcus multilocularis lysosomal alpha glucosidase 0.0338 0.0928 0.0927
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus granulosus g protein coupled receptor 0.0437 0.1217 0.1367
Loa Loa (eye worm) hypothetical protein 0.0052 0.0086 0.0098
Schistosoma mansoni lipoxygenase 0.0112 0.0263 0.0295
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0437 0.1217 0.1216
Leishmania major dihydrolipoamide dehydrogenase, putative 0.004 0.0053 0.0113
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0518 0.0581
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0067
Loa Loa (eye worm) hypothetical protein 0.0116 0.0275 0.0311
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0116 0.0275 0.0311
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0059 0.0067
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0009 0.0009
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0052 0.0086 0.0096
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0052 0.0058
Schistosoma mansoni calcium-activated potassium channel 0.0097 0.0221 0.0247
Trichomonas vaginalis glucosylceramidase, putative 0.0308 0.084 0.3229
Schistosoma mansoni glutaminase 0.0896 0.2565 0.2883
Schistosoma mansoni sodium-dependent amino acid transporter 0.0052 0.0086 0.0096
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0198 0.0518 0.0587
Echinococcus granulosus snurportin 1 0.0615 0.174 0.1956
Echinococcus multilocularis fmrfamide receptor 0.0437 0.1217 0.1216
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0055 0.0096 0.0183
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0055 0.0096 0.0192
Loa Loa (eye worm) hypothetical protein 0.0304 0.0827 0.0939
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0055 0.0096 0.0182
Echinococcus granulosus acetylcholinesterase 0.0941 0.2697 0.3032
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0437 0.1217 0.1381
Leishmania major dihydrolipoamide dehydrogenase, putative 0.004 0.0053 0.0113
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0108 0.0251 0.0917
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Brugia malayi Melatonin receptor type 1A 0.0437 0.1217 0.1381
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0097 0.0221 0.025
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0155 0.032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0437 0.1217 0.1216
Echinococcus multilocularis G-protein coupled receptor, putative 0.0437 0.1217 0.1216
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Toxoplasma gondii hypothetical protein 0.0038 0.0047 0.081
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Echinococcus granulosus neutral alpha glucosidase AB 0.0075 0.0155 0.0174
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 0.0161 0.0408 0.0908
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1725 0.6704
Loa Loa (eye worm) hypothetical protein 0.0076 0.0159 0.018
Loa Loa (eye worm) hypothetical protein 0.2172 0.631 0.716
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0065 0.0127 0.0144
Brugia malayi G-protein coupled receptor 0.0437 0.1217 0.1381
Schistosoma mansoni neuropeptide receptor 0.0437 0.1217 0.1367
Echinococcus multilocularis orexin receptor type 2 0.0437 0.1217 0.1216
Trypanosoma cruzi DNA repair protein, putative 0.0033 0.0031 0.0035
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0052 0.0086 0.0085
Chlamydia trachomatis recombinase RecA 0.0106 0.0247 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.004 0.0046
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0009 0.0009
Loa Loa (eye worm) doublecortin family protein 0.004 0.0052 0.0059
Trichomonas vaginalis penicillin-binding protein, putative 0.0085 0.0184 0.0657
Toxoplasma gondii cytochrome p450 superfamily protein 0.0055 0.0096 0.1896
Trypanosoma brucei protein kinase, putative 0.0059 0.0109 0.0224
Plasmodium vivax potassium channel, putative 0.0097 0.0221 0.7935
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0065 0.0127 0.0126
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0055 0.0096 0.0359
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0055 0.0096 0.0182
Echinococcus granulosus 7tm_1 domain containing protein 0.0437 0.1217 0.1367
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0142 0.0351 0.0398
Loa Loa (eye worm) hypothetical protein 0.0052 0.0086 0.0098
Schistosoma mansoni amine oxidase 0.0042 0.0059 0.0066
Echinococcus multilocularis flap endonuclease 1 0.0054 0.0094 0.0093
Schistosoma mansoni amine GPCR 0.0437 0.1217 0.1367
Schistosoma mansoni rab6-interacting 0.004 0.0052 0.0058
Brugia malayi jmjC domain containing protein 0.0033 0.0031 0.0035
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.0161 0.0408 0.1536
Mycobacterium ulcerans hypothetical protein 0.0038 0.0047 0.0171
Onchocerca volvulus 0.0437 0.1217 0.5653
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0116 0.0276 0.0313
Giardia lamblia Flap structure-specific endonuclease 0.0054 0.0094 0.0244
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0221 0.0247
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Schistosoma mansoni hypothetical protein 0.0079 0.0166 0.0185
Echinococcus granulosus small conductance calcium activated potassium 0.2172 0.631 0.7096
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0105 0.0243 0.0474
Brugia malayi MH1 domain containing protein 0.0029 0.002 0.0023
Onchocerca volvulus 0.0026 0.0011 0.0033
Trypanosoma cruzi cytochrome P450, putative 0.009 0.0201 0.0424
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0103 0.0237 0.0534
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0161 0.6352
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0055 0.0096 0.0359
Loa Loa (eye worm) hypothetical protein 0.0052 0.0086 0.0098
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0092 0.0205 0.0229
Mycobacterium ulcerans transmembrane cation transporter 0.0097 0.0221 0.0847
Echinococcus granulosus calcium activated potassium channel variant 0.0097 0.0221 0.0247
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0054 0.0094 0.0179
Echinococcus granulosus rhodopsin orphan GPCR 0.0437 0.1217 0.1367
Schistosoma mansoni ap endonuclease 0.0103 0.0237 0.0266
Treponema pallidum sodium- and chloride- dependent transporter 0.0304 0.0827 0.476
Echinococcus multilocularis mothers against decapentaplegic 5 0.0053 0.0089 0.0088
Echinococcus multilocularis beta LACTamase domain containing family member 0.0085 0.0184 0.0183
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0437 0.1217 0.1367
Loa Loa (eye worm) norepinephrine transporter 0.0304 0.0827 0.0939
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0052 0.0086 0.0096
Brugia malayi Pre-SET motif family protein 0.0097 0.0219 0.0249
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0055 0.0096 0.0359
Echinococcus multilocularis somatostatin receptor 0.0437 0.1217 0.1216
Onchocerca volvulus 0.0097 0.0221 0.1011
Mycobacterium leprae conserved hypothetical protein 0.0085 0.0184 0.1027
Brugia malayi cytoplasmic intermediate filament protein 0.0062 0.0117 0.0133
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0097 0.0219 0.4683
Trypanosoma brucei C-8 sterol isomerase, putative 0.1515 0.4382 1
Plasmodium falciparum protease, putative 0.0038 0.0047 0.1362
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Echinococcus granulosus histone acetyltransferase KAT2B 0.0094 0.0211 0.0236
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0029 0.0022 0.0024
Echinococcus multilocularis acetylcholinesterase 0.0941 0.2697 0.2696
Echinococcus granulosus glycine receptor subunit beta 0.0142 0.0351 0.0393
Plasmodium falciparum flap endonuclease 1 0.0054 0.0094 0.3119
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0142 0.0351 0.0393
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0085 0.0184 0.0209
Schistosoma mansoni Smad4 0.0023 0.0004 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0437 0.1217 0.1367
Treponema pallidum fructose-bisphosphate aldolase 0.061 0.1725 1
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0059 0.1819
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0055 0.0096 0.0359
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0437 0.1217 0.1367
Echinococcus multilocularis muscleblind protein 1 0.0158 0.0398 0.0397
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0142 0.0351 0.0398
Schistosoma mansoni jumonji domain containing protein 0.0033 0.0031 0.0033
Onchocerca volvulus 0.0116 0.0275 0.1263
Echinococcus granulosus histone acetyltransferase KAT2B 0.031 0.0846 0.095
Echinococcus multilocularis muscleblind protein 0.0158 0.0398 0.0397
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0437 0.1217 0.1367
Trichomonas vaginalis D-aminoacylase, putative 0.0085 0.0184 0.0657
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0161 0.0615
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0161 0.0615
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0161 0.5678
Loa Loa (eye worm) ACC-1 protein 0.0142 0.0351 0.0398
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0072 0.0129
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0163 0.0413 0.0469
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0052 0.0086 0.0096
Mycobacterium ulcerans oxidoreductase 0.0042 0.0059 0.0218
Schistosoma mansoni alpha-1 adrenergic receptor 0.0437 0.1217 0.1367
Onchocerca volvulus 0.0159 0.0402 0.1855
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0059 0.1819
Trypanosoma cruzi C-14 sterol reductase, putative 0.0094 0.0211 0.0448
Brugia malayi Smad1 0.0053 0.0089 0.0101
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0103 0.0237 0.0507
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0059 0.0066
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0142 0.0351 0.0398
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0219 0.0245
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0106 0.0247 0.5934
Echinococcus granulosus caspase 2 0.0098 0.0223 0.0249
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0052 0.0086 0.0096
Brugia malayi excitatory GABA receptor EXP-1A 0.0142 0.0351 0.0398
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0159 0.0402 0.0786
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0097 0.0221 0.022
Loa Loa (eye worm) TYRA-2 protein 0.0437 0.1217 0.1381
Echinococcus multilocularis glutamate receptor 2 0.0023 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.3024 0.8813 1
Onchocerca volvulus 0.0065 0.0127 0.0574
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0186 0.048 0.1816
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0052 0.0086 0.0098
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0304 0.0827 0.0939
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0083 0.0157
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0161 0.0873
Loa Loa (eye worm) G-protein coupled receptor 0.0437 0.1217 0.1381
Echinococcus granulosus lysine specific demethylase 5A 0.0127 0.0308 0.0345
Brugia malayi hypothetical protein 0.0437 0.1217 0.1381
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0076 0.0159 0.018
Onchocerca volvulus Pyruvate kinase homolog 0.0105 0.0243 0.1118
Schistosoma mansoni hypothetical protein 0.0052 0.0086 0.0096
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1725 0.6704
Schistosoma mansoni opsin-like receptor 0.0437 0.1217 0.1367
Echinococcus multilocularis neuropeptide receptor 0.0437 0.1217 0.1216
Echinococcus multilocularis lysine specific demethylase 5A 0.0122 0.0293 0.0292
Echinococcus granulosus beta LACTamase domain containing family member 0.0085 0.0184 0.0206
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0437 0.1217 0.1367
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.004 0.0053 0.0052
Leishmania major pyruvate kinase 0.0105 0.0243 0.0549
Mycobacterium tuberculosis Probable lipase LipD 0.0085 0.0184 0.0357
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0142 0.0351 0.0398
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0052 0.0086 0.0098
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Schistosoma mansoni transcription factor LCR-F1 0.0078 0.0164 0.0184
Onchocerca volvulus 0.0085 0.0184 0.0843
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0055 0.0096 0.0359
Mycobacterium ulcerans hypothetical protein 0.0085 0.0184 0.0706
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0103 0.0237 0.0266
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0437 0.1217 0.1367
Leishmania major cytochrome p450-like protein 0.0055 0.0096 0.0211
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0186 0.048 0.0538
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0112 0.0263 0.0295
Echinococcus multilocularis rhodopsin orphan GPCR 0.0437 0.1217 0.1216
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0093 0.0207 0.0232
Brugia malayi G protein-coupled receptor 0.0437 0.1217 0.1381
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0308 0.084 0.0953
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.006 0.0111 0.2247
Echinococcus granulosus tm gpcr rhodopsin 0.0437 0.1217 0.1367
Leishmania major hypothetical protein, conserved 0.0033 0.0031 0.0062
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0067
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0103 0.0237 0.0269
Onchocerca volvulus 0.0076 0.0159 0.0724
Loa Loa (eye worm) hypothetical protein 0.0052 0.0086 0.0098
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0109 0.0215
Echinococcus multilocularis serotonin receptor 0.1559 0.451 0.451
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0016 0.0159
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0032 0.0029 0.0049
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Onchocerca volvulus 0.0097 0.0221 0.1011
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0615 0.174 0.1974
Mycobacterium leprae putative cytochrome p450 0.0055 0.0096 0.0522
Onchocerca volvulus 0.004 0.0052 0.0226
Echinococcus multilocularis snurportin 1 0.0615 0.174 0.1739
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0097 0.0221 0.0469
Brugia malayi Glycosyl hydrolases family 31 protein 0.0338 0.0928 0.1053
Loa Loa (eye worm) hypothetical protein 0.0041 0.0055 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0437 0.1217 0.1216
Echinococcus granulosus intestinal type alkaline phosphatase 0.0346 0.0951 0.1068
Schistosoma mansoni Smad4 0.0023 0.0004 0.0003
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.0109 0.2209
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, putative 0.0161 0.0408 0.0908
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0055 0.0096 0.0359
Loa Loa (eye worm) hypothetical protein 0.0052 0.0086 0.0098
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0052 0.0086 0.0098
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0304 0.0827 0.0929
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0437 0.1217 0.1367
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0052 0.0086 0.0098
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0437 0.1217 0.1367
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0012 0.0016
Onchocerca volvulus Neuropeptide F receptor homolog 0.0437 0.1217 0.5653
Echinococcus granulosus para nitrobenzyl esterase 0.0159 0.0402 0.0451
Plasmodium falciparum protoporphyrinogen oxidase 0.0042 0.0059 0.1819
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Loa Loa (eye worm) hypothetical protein 0.0058 0.0104 0.0118
Echinococcus multilocularis pyruvate kinase 0.0054 0.0093 0.0092
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0097 0.0219 0.0245
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0059 0.011
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0142 0.0351 0.035
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0055 0.0096 0.0359
Plasmodium falciparum potassium channel 0.0097 0.0221 0.7935
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0038 0.0048 0.0211
Echinococcus multilocularis neutral alpha glucosidase AB 0.0075 0.0155 0.0154
Brugia malayi CAAX amino terminal protease family protein 0.0186 0.048 0.0544
Echinococcus granulosus sodium:glucose cotransporter 0.0041 0.0055 0.006
Plasmodium vivax pyruvate kinase, putative 0.0105 0.0243 0.8806
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1456 0.4211 0.421
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0072 0.0216
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0076 0.0159 0.018
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Trichomonas vaginalis glucosylceramidase, putative 0.0308 0.084 0.3229
Trypanosoma cruzi hypothetical protein, conserved 0.0097 0.0221 0.0469
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.01 0.0229 0.8241
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0059 0.01
Onchocerca volvulus 0.0052 0.0086 0.0386
Mycobacterium tuberculosis Carboxylesterase LipT 0.0159 0.0402 0.0786
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0142 0.0351 0.0398
Echinococcus granulosus thioredoxin glutathione reductase 0.0117 0.0279 0.0313
Loa Loa (eye worm) hypothetical protein 0.0137 0.0336 0.0381
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0437 0.1217 0.1367
Echinococcus granulosus lamin b receptor 0.0094 0.0211 0.0236
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0004
Echinococcus multilocularis neuropeptide receptor 0.0437 0.1217 0.1216
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0055 0.0096 0.0359
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0437 0.1217 0.1216
Brugia malayi jmjC domain containing protein 0.0122 0.0293 0.0333
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0142 0.0351 0.0398
Loa Loa (eye worm) hypothetical protein 0.0158 0.0398 0.0452
Mycobacterium ulcerans carboxylesterase, LipT 0.0159 0.0402 0.1554
Plasmodium falciparum pyruvate kinase 0.0105 0.0243 0.8806
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.0109 0.0215
Loa Loa (eye worm) hypothetical protein 0.004 0.0052 0.0059
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0097 0.0221 0.025
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0103 0.0237 0.0516
Mycobacterium ulcerans dehydrogenase 0.0042 0.0059 0.0218
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0009 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0437 0.1217 0.1216
Leishmania major alpha glucosidase II subunit, putative 0.0075 0.0155 0.0347
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0004 0.0001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0052 0.0086 0.0096
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0097 0.0221 0.025
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0109 0.0362
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0104 0.0212
Loa Loa (eye worm) latrophilin receptor protein 2 0.0052 0.0086 0.0098
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Loa Loa (eye worm) uncoordinated protein 58 0.0097 0.0221 0.025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0053 0.0085
Onchocerca volvulus 0.0142 0.0351 0.1617
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0093 0.0207 0.0235
Echinococcus granulosus nAChR subunit 0.0076 0.0159 0.0178
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0052 0.0086 0.1691
Brugia malayi hypothetical protein 0.0437 0.1217 0.1381
Brugia malayi Calcitonin receptor-like protein seb-1 0.0163 0.0413 0.0469
Echinococcus multilocularis polycomb protein SCMH1 0.0052 0.0088 0.0087
Leishmania major C-8 sterol isomerase-like protein 0.1515 0.4382 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0437 0.1217 0.1367
Loa Loa (eye worm) hypothetical protein 0.0052 0.0086 0.0098
Brugia malayi hypothetical protein 0.033 0.0903 0.1024
Loa Loa (eye worm) hypothetical protein 0.0159 0.0402 0.0456
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0304 0.0827 0.0939
Loa Loa (eye worm) hypothetical protein 0.0076 0.0159 0.018
Echinococcus multilocularis g protein coupled receptor 0.0437 0.1217 0.1216
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0052 0.0058
Onchocerca volvulus 0.0437 0.1217 0.5653
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0192 0.05 0.2884
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0142 0.0351 0.035
Echinococcus granulosus glutamate receptor 2 0.0023 0.0002 0.0001
Trypanosoma brucei calcium-activated potassium channel, putative 0.0097 0.0221 0.0478
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0186 0.048 0.1063
Loa Loa (eye worm) glutathione reductase 0.0116 0.0275 0.0312
Brugia malayi amine oxidase, flavin-containing family protein 0.0042 0.0059 0.0067
Onchocerca volvulus 0.0097 0.0221 0.1011
Trichomonas vaginalis D-aminoacylase, putative 0.0085 0.0184 0.0657
Schistosoma mansoni acetylcholinesterase 0.0159 0.0402 0.0451
Echinococcus multilocularis apoptotic protease activating factor 1 0.0079 0.0166 0.0165
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0065 0.0127 0.0141
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.004 0.0053 0.1567
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0109 0.0362
Loa Loa (eye worm) hypothetical protein 0.0085 0.0184 0.0209
Echinococcus multilocularis histone acetyltransferase MYST2 0.0059 0.0109 0.0108
Schistosoma mansoni myelin transcription factor 1 myt1 0.0059 0.0109 0.0121
Schistosoma mansoni opsin-like receptor 0.0437 0.1217 0.1367
Brugia malayi NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor 0.0161 0.0408 0.0463
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0055 0.0096 0.0182
Onchocerca volvulus 0.0413 0.1147 0.5329
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0055 0.0096 0.0182
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.0109 0.0243
Schistosoma mansoni flap endonuclease-1 0.0049 0.0078 0.0087
Toxoplasma gondii pyruvate kinase PyK1 0.0105 0.0243 0.5235
Brugia malayi G-protein coupled receptor 0.0437 0.1217 0.1381
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0122 0.0463
Echinococcus granulosus neuropeptide receptor 0.0437 0.1217 0.1367
Onchocerca volvulus 0.0097 0.0221 0.1011
Onchocerca volvulus 0.0437 0.1217 0.5653
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0221 0.0247
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0062 0.0117 0.0133
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.01 0.0229 0.083
Brugia malayi Glycosyl hydrolases family 31 protein 0.0075 0.0155 0.0176
Brugia malayi Flap endonuclease-1 0.0054 0.0094 0.0106
Onchocerca volvulus 0.0159 0.0402 0.1855
Schistosoma mansoni hypothetical protein 0.0437 0.1217 0.1367
Loa Loa (eye worm) hypothetical protein 0.0159 0.0402 0.0456
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.004 0.0053 0.0113
Brugia malayi SWIRM domain containing protein 0.0042 0.0059 0.0067
Onchocerca volvulus Huntingtin homolog 0.0137 0.0336 0.1549
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0437 0.1217 0.1216
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.01 0.0229 0.8241
Trichomonas vaginalis sucrase-isomaltase, putative 0.0075 0.0155 0.0543
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0055 0.0096 0.0359
Brugia malayi Carboxylesterase family protein 0.0941 0.2697 0.306
Entamoeba histolytica acetyltransferase, GNAT family 0.0086 0.0188 0.107
Echinococcus multilocularis fmrfamide receptor 0.0437 0.1217 0.1216
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0559 0.1577 0.3107
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0053 0.0085
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0059 0.011
Onchocerca volvulus 0.0052 0.0088 0.0392
Mycobacterium ulcerans esterase/lipase LipP 0.0085 0.0184 0.0706
Echinococcus granulosus nAChR subunit 0.0142 0.0351 0.0393
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0159 0.0402 0.0451
Echinococcus multilocularis neuroligin 0.0159 0.0402 0.0401
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0142 0.0351 0.0393
Brugia malayi ORL1-like opioid receptor 0.0437 0.1217 0.1381
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0111 0.0262 0.1503
Entamoeba histolytica hypothetical protein 0.0111 0.0262 0.1503
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0142 0.0351 0.0398
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0186 0.048 0.1063
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0055 0.0096 0.0359
Brugia malayi Pyruvate kinase, muscle isozyme 0.0105 0.0243 0.0276
Loa Loa (eye worm) beta-lactamase 0.0085 0.0184 0.0209
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0437 0.1217 0.1367
Mycobacterium leprae Probable pyruvate kinase PykA 0.0105 0.0243 0.1362
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.004 0.0053 0.1567
Schistosoma mansoni hypothetical protein 0.0078 0.0164 0.0184
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0055 0.0096 0.0182
Echinococcus granulosus pyruvate kinase 0.0054 0.0093 0.0104
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0437 0.1217 0.1367
Schistosoma mansoni jumonji/arid domain-containing protein 0.0127 0.0308 0.0345
Leishmania major cytochrome p450-like protein 0.0055 0.0096 0.0211
Echinococcus multilocularis twik family of potassium channels 0.0097 0.0221 0.022
Schistosoma mansoni biogenic amine (5HT) receptor 0.0804 0.2295 0.258
Loa Loa (eye worm) hypothetical protein 0.0111 0.0262 0.0297
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0155 0.0882
Brugia malayi hypothetical protein 0.0437 0.1217 0.1381
Onchocerca volvulus 0.0142 0.0351 0.1617
Echinococcus multilocularis g protein coupled receptor 0.0437 0.1217 0.1216
Schistosoma mansoni hypothetical protein 0.0437 0.1217 0.1367
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0142 0.0351 0.0398
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0529 0.2008
Loa Loa (eye worm) MH1 domain-containing protein 0.0023 0.0004 0.0004
Brugia malayi hypothetical protein 0.0437 0.1217 0.1381
Schistosoma mansoni ran 0.0042 0.0059 0.0066
Brugia malayi beta-lactamase 0.0085 0.0184 0.0209
Brugia malayi Cytochrome P450 family protein 0.0113 0.0266 0.0302
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0059 0.01
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0346 0.0951 0.095
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0078 0.0163 0.0182
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0112 0.0263 0.0262
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0108 0.0253 0.0287
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0055 0.0096 0.0182
Loa Loa (eye worm) hypothetical protein 0.0137 0.0336 0.0381
Echinococcus granulosus tachykinin peptides receptor 99D 0.0437 0.1217 0.1367
Echinococcus granulosus rhodopsin orphan GPCR 0.0437 0.1217 0.1367
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0055 0.0096 0.0211
Loa Loa (eye worm) hypothetical protein 0.004 0.0052 0.0059
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0663 0.1882 0.2135
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0161 0.6352
Trichomonas vaginalis glucosylceramidase, putative 0.0308 0.084 0.3229
Loa Loa (eye worm) hypothetical protein 0.1559 0.451 0.5118
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0038 0.0047 0.0087
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0059 0.1819
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0038 0.0045 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0529 0.2008
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0055 0.0096 0.0359
Echinococcus granulosus polycomb protein SCMH1 0.0052 0.0088 0.0098
Echinococcus granulosus g protein coupled receptor 0.0437 0.1217 0.1367
Echinococcus multilocularis solute carrier family 5 0.0041 0.0055 0.0054
Echinococcus granulosus 7TM GPCR rhodopsin 0.0437 0.1217 0.1367
Schistosoma mansoni smad 0.0053 0.0089 0.0099
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0097 0.0221 0.025
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Mycobacterium leprae Probable lipase LipE 0.0085 0.0184 0.1027
Schistosoma mansoni smad 0.0023 0.0004 0.0003
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0298 0.0809 0.3147
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0106 0.0247 0.1382
Schistosoma mansoni lamin 0.0116 0.0275 0.0308
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0155 0.032
Entamoeba histolytica hypothetical protein 0.0026 0.0012 0.0046
Trypanosoma cruzi ion transport protein, putative 0.0097 0.0221 0.0469
Echinococcus granulosus lamin 0.0116 0.0275 0.0308
Entamoeba histolytica hypothetical protein 0.0076 0.0159 0.0902
Brugia malayi hypothetical protein 0.0065 0.0127 0.0144
Brugia malayi latrophilin 2 splice variant baaae 0.0111 0.0262 0.0297
Onchocerca volvulus Putative nachr subunit 0.0142 0.0351 0.1617
Echinococcus granulosus fmrfamide receptor 0.0437 0.1217 0.1367
Entamoeba histolytica CAAX prenyl protease family 0.0186 0.048 0.2766
Loa Loa (eye worm) hypothetical protein 0.0033 0.0031 0.0035
Loa Loa (eye worm) hypothetical protein 0.1559 0.451 0.5118
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0437 0.1217 0.1381
Loa Loa (eye worm) hypothetical protein 0.0052 0.0088 0.01
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0065 0.0127 0.0144
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0041 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.0076 0.0159 0.018
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0103 0.0237 0.5688
Trichomonas vaginalis ran, putative 0.0042 0.0059 0.0166
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0092 0.0205 0.0785
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0097 0.0221 0.022
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0094 0.0211 0.756
Schistosoma mansoni neuroligin 3 (S09 family) 0.0159 0.0402 0.0451
Echinococcus granulosus BC026374 protein S09 family 0.0159 0.0402 0.0451
Loa Loa (eye worm) hypothetical protein 0.0076 0.0159 0.018
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0529 0.2008
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0097 0.0221 0.0478
Schistosoma mansoni sodium/chloride dependent transporter 0.0052 0.0088 0.0098
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0018
Schistosoma mansoni hypothetical protein 0.0097 0.0221 0.0247
Onchocerca volvulus 0.0041 0.0055 0.0238
Schistosoma mansoni nAChR subunit 0.0142 0.0351 0.0393
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0031 0.0034
Loa Loa (eye worm) hypothetical protein 0.0073 0.015 0.017
Echinococcus multilocularis neuropeptides capa receptor 0.0437 0.1217 0.1216
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0012 0.0019
Entamoeba histolytica hypothetical protein 0.0078 0.0164 0.0934
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.009 0.0201 0.077
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0142 0.0351 0.0393
Chlamydia trachomatis protoporphyrinogen oxidase 0.0042 0.0059 0.2034
Schistosoma mansoni intermediate filament proteins 0.0116 0.0275 0.0308
Echinococcus granulosus potassium channel subfamily K 8 0.0097 0.0221 0.0247
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus granulosus peptide allatostatin:somatostatin 0.0437 0.1217 0.1367
Trypanosoma brucei trypanothione reductase 0.0116 0.0275 0.0603
Echinococcus multilocularis g protein coupled receptor 0.0437 0.1217 0.1216
Echinococcus multilocularis potassium channel subfamily K 8 0.0097 0.0221 0.022
Echinococcus multilocularis potassium channel subfamily K 0.0097 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0097 0.0221 0.025
Loa Loa (eye worm) hypothetical protein 0.0076 0.0159 0.018
Echinococcus granulosus muscleblind protein 0.0158 0.0398 0.0447
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0142 0.0351 0.035
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0122 0.0121
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0059 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0109 0.0122
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0346 0.0951 0.095
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0161 0.3375
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0116 0.0276 0.0309
Echinococcus multilocularis pyruvate kinase 0.0105 0.0243 0.0243
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0033 0.0031 0.0045
Mycobacterium tuberculosis Probable integral membrane protein 0.0038 0.0047 0.0087
Echinococcus granulosus somatostatin receptor 0.0437 0.1217 0.1367
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0142 0.0351 0.035
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0161 0.3769
Brugia malayi Muscleblind-like protein 0.0158 0.0398 0.0452
Brugia malayi RE15519p 0.0437 0.1217 0.1381
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0097 0.0219 0.0218
Entamoeba histolytica hypothetical protein 0.0047 0.0072 0.0398
Loa Loa (eye worm) jmjC domain-containing protein 0.0127 0.0308 0.0349
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0142 0.0351 0.0393
Echinococcus granulosus alpha 1A adrenergic receptor 0.0437 0.1217 0.1367
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0055 0.0096 0.0359
Trichomonas vaginalis protein kinase inhibitor, putative 0.0065 0.0126 0.0429
Echinococcus granulosus L aminoadipate semialdehyde 0.0093 0.0207 0.0232
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0142 0.0351 0.0393
Schistosoma mansoni growth hormone secretagogue receptor 0.0437 0.1217 0.1367
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0264 0.071 0.1395
Echinococcus granulosus serotonin receptor 0.0437 0.1217 0.1367
Schistosoma mansoni cpg binding protein 0.0092 0.0206 0.0231
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0109 0.0362
Loa Loa (eye worm) hypothetical protein 0.0186 0.048 0.0544
Schistosoma mansoni biogenic amine receptor 0.0437 0.1217 0.1367
Brugia malayi hypothetical protein 0.0137 0.0336 0.0381
Leishmania major pyruvate kinase 0.0105 0.0243 0.0549
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0092 0.0205 0.0229
Toxoplasma gondii ion channel protein 0.0097 0.0221 0.4717
Trypanosoma brucei glucosidase, putative 0.0075 0.0155 0.0329
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Loa Loa (eye worm) hypothetical protein 0.0033 0.0031 0.0035
Brugia malayi Trypsin family protein 0.0095 0.0215 0.0244
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0033 0.0031 0.0033
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0103 0.0237 0.1103
Brugia malayi GH02984p 0.037 0.1021 0.1158
Schistosoma mansoni amine GPCR 0.0437 0.1217 0.1367
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.004 0.0053 0.0094
Leishmania major C-14 sterol reductase, putative 0.0094 0.0211 0.0475
Brugia malayi MH1 domain containing protein 0.0029 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0105 0.0243 0.0276
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0437 0.1217 0.1381
Trichomonas vaginalis mercuric reductase, putative 0.004 0.0053 0.014
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0042 0.0059 0.0058
Loa Loa (eye worm) hypothetical protein 0.0067 0.0133 0.0151
Plasmodium falciparum glutathione reductase 0.0116 0.0275 1
Plasmodium falciparum glutathione reductase 0.004 0.0053 0.1567
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0294 0.0797 0.1566
Loa Loa (eye worm) hypothetical protein 0.033 0.0903 0.1024
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.0109 0.0124
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0294 0.0797 0.1566
Mycobacterium tuberculosis Probable oxidoreductase 0.0294 0.0797 0.1566
Echinococcus multilocularis phd:f box containing protein 0.0033 0.0031 0.003
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0059 0.1819
Trichomonas vaginalis maltase-glucoamylase, putative 0.0075 0.0155 0.0543
Trypanosoma cruzi cytochrome P450, putative 0.009 0.0201 0.0424
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0052 0.1542
Leishmania major cytochrome p450-like protein 0.009 0.0201 0.0451
Echinococcus granulosus rhodopsin orphan GPCR 0.0437 0.1217 0.1367
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0203 0.0227
Loa Loa (eye worm) hypothetical protein 0.0052 0.0086 0.0098
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0002 0.0001
Brugia malayi MAP kinase sur-1 0.0059 0.0109 0.0124
Echinococcus granulosus rhodopsin orphan GPCR 0.0437 0.1217 0.1367
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0075 0.0155 0.3246
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0226 0.0598 0.0597
Brugia malayi GnHR receptor homolog 0.0437 0.1217 0.1381
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Schistosoma mansoni high-affinity choline transporter 0.037 0.1021 0.1147
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0031 0.0035
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0094 0.0211 0.4494
Schistosoma mansoni hypothetical protein 0.1246 0.3592 0.4038
Schistosoma mansoni neuropeptide receptor 0.0437 0.1217 0.1367
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.01 0.0229 0.4899
Brugia malayi Doublecortin family protein 0.004 0.0052 0.0059
Schistosoma mansoni opsin-like receptor 0.0437 0.1217 0.1367
Onchocerca volvulus Pyruvate kinase homolog 0.0105 0.0243 0.1118
Schistosoma mansoni pyruvate kinase 0.0054 0.0093 0.0104
Brugia malayi Carboxylesterase family protein 0.0159 0.0402 0.0456
Brugia malayi hypothetical protein 0.0161 0.0407 0.0462
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0002 0.0001
Schistosoma mansoni smad1 5 8 and 0.0053 0.0089 0.0099
Brugia malayi glucose-6-phosphate dehydrogenase 0.0092 0.0205 0.0232
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0437 0.1217 0.1367
Schistosoma mansoni hypothetical protein 0.0437 0.1217 0.1367
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0032 0.0028 0.0032
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0264 0.071 0.4013
Schistosoma mansoni hypothetical protein 0.018 0.0463 0.0519
Echinococcus granulosus alkaline phosphatase 0.0346 0.0951 0.1068
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0518 0.0581
Plasmodium falciparum histone acetyltransferase GCN5 0.0086 0.0188 0.6688
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0038 0.0047 0.0087
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0041 0.0055 0.006
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0142 0.0351 0.0398
Echinococcus multilocularis rhodopsin orphan GPCR 0.0437 0.1217 0.1216
Brugia malayi DnaJ domain containing protein 0.0065 0.0126 0.0143
Onchocerca volvulus 0.0076 0.0159 0.0724
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0052 0.0086 0.1691
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0012 0.0031
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0033 0.0031 0.0044
Plasmodium vivax hypothetical protein, conserved 0.0052 0.0086 0.2845
Onchocerca volvulus 0.0159 0.0402 0.1855
Schistosoma mansoni caspase-7 (C14 family) 0.0098 0.0223 0.0249
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0055 0.0096 0.0359
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0076 0.0159 0.018
Echinococcus granulosus glycine receptor subunit beta 0.0142 0.0351 0.0393
Mycobacterium ulcerans ion transport protein 0.0097 0.0221 0.0847
Loa Loa (eye worm) glutaminase 2 0.0896 0.2565 0.291
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.0109 0.0122
Brugia malayi Latrophilin receptor protein 2 0.0052 0.0086 0.0098
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0155 0.0882
Mycobacterium tuberculosis Probable dehydrogenase 0.0264 0.071 0.1395
Echinococcus granulosus GPCR family 2 0.0052 0.0086 0.0096
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0155 0.0543
Chlamydia trachomatis pyruvate kinase 0.0105 0.0243 0.9852
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0039 0.0044
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.004 0.0053 0.006
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0437 0.1217 0.1216
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0093 0.0105
Schistosoma mansoni gliotactin 0.0159 0.0402 0.0451
Echinococcus multilocularis rhodopsin orphan GPCR 0.0437 0.1217 0.1216
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0437 0.1217 0.1367
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0941 0.2697 0.3032
Entamoeba histolytica Flap nuclease, putative 0.0054 0.0094 0.0524
Treponema pallidum recombinase A 0.0106 0.0247 0.1374
Onchocerca volvulus 0.0116 0.0275 0.1263
Echinococcus granulosus sodium:myo inositol cotransporter 0.0041 0.0055 0.006
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Schistosoma mansoni single-minded 0.0048 0.0076 0.0084
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0264 0.071 0.1395
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0072 0.0216
Loa Loa (eye worm) glutaminase 0.0896 0.2565 0.291
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.004 0.0053 0.0058
Echinococcus multilocularis allatostatin A receptor 0.0437 0.1217 0.1216
Brugia malayi intermediate filament protein 0.0116 0.0275 0.0311
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0221 0.0247
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0142 0.0351 0.035
Loa Loa (eye worm) neuropeptide F receptor 0.0437 0.1217 0.1381
Brugia malayi jmjC domain containing protein 0.0033 0.0031 0.0035
Schistosoma mansoni lamin 0.0116 0.0275 0.0308
Echinococcus granulosus G protein coupled receptor 139 0.0437 0.1217 0.1367
Trichomonas vaginalis pyruvate kinase, putative 0.0105 0.0243 0.0889
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Loa Loa (eye worm) cytochrome P450 family protein 0.009 0.0201 0.0228
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Schistosoma mansoni hypothetical protein 0.0052 0.0086 0.0096
Loa Loa (eye worm) flap endonuclease-1 0.0054 0.0094 0.0106
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0041 0.0055 0.0975
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0052 0.0086 0.0096
Echinococcus multilocularis acetylcholinesterase 0.0941 0.2697 0.2696
Plasmodium falciparum amino acid transporter, putative 0.0052 0.0086 0.2845
Leishmania major NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0161 0.0408 0.0925
Giardia lamblia Histone acetyltransferase GCN5 0.0086 0.0188 0.0807
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0004 0.0004
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0059 0.0066
Brugia malayi CXXC zinc finger family protein 0.0087 0.0192 0.0218
Toxoplasma gondii hypothetical protein 0.0027 0.0013 0.0031
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0437 0.1217 0.1367
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0097 0.0221 0.025
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.004 0.0053 0.104
Onchocerca volvulus 0.0079 0.0166 0.0756
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Onchocerca volvulus 0.0052 0.0086 0.0386
Onchocerca volvulus 0.0042 0.0059 0.026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0437 0.1217 0.1216
Echinococcus multilocularis caspase 2 0.0098 0.0223 0.0222
Trypanosoma brucei hypothetical protein, conserved 0.0085 0.0184 0.0396
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0078 0.0164 0.0163
Trypanosoma cruzi trypanothione reductase, putative 0.0116 0.0275 0.0594
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0052 0.0088 0.0098
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Giardia lamblia Fructose-bisphosphate aldolase 0.061 0.1725 1
Mycobacterium tuberculosis Conserved protein 0.0085 0.0184 0.0357
Plasmodium vivax SET domain protein, putative 0.0097 0.0219 0.7878
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0004 0.0001
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0221 0.0247
Echinococcus granulosus carboxylesterase 5A 0.0941 0.2697 0.3032
Echinococcus multilocularis neuropeptide Y receptor 0.0437 0.1217 0.1216
Schistosoma mansoni nAChR subunit 0.0142 0.0351 0.0393
Echinococcus multilocularis glycine receptor subunit beta 0.0142 0.0351 0.035
Echinococcus granulosus pyruvate kinase 0.0105 0.0243 0.0273
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0346 0.0951 0.1068
Loa Loa (eye worm) hypothetical protein 0.0437 0.1217 0.1381
Echinococcus multilocularis neuropeptide receptor A26 0.0437 0.1217 0.1216
Loa Loa (eye worm) hypothetical protein 0.0076 0.0159 0.018
Onchocerca volvulus 0.0142 0.0351 0.1617
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0437 0.1217 0.1367
Brugia malayi sulfakinin receptor protein 0.0437 0.1217 0.1381
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.004 0.0053 0.104
Onchocerca volvulus 0.0087 0.0192 0.0877
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0052 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Echinococcus multilocularis glycine receptor subunit beta 0.0142 0.0351 0.035
Loa Loa (eye worm) hypothetical protein 0.0097 0.0221 0.025
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0039 0.0038
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0109 0.0215
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0054 0.0094 0.0188
Echinococcus granulosus g protein coupled receptor 0.0437 0.1217 0.1367
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0078 0.0164 0.0184
Loa Loa (eye worm) hypothetical protein 0.0065 0.0127 0.0144
Loa Loa (eye worm) DnaJ domain-containing protein 0.0065 0.0126 0.0143
Leishmania major sterol C-24 reductase, putative 0.0094 0.0211 0.0475
Loa Loa (eye worm) neuropeptide F receptor 0.0437 0.1217 0.1381
Brugia malayi beta-lactamase family protein 0.0085 0.0184 0.0209
Loa Loa (eye worm) hypothetical protein 0.0142 0.0351 0.0398
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0031 0.0034
Echinococcus granulosus biogenic amine 5HT receptor 0.1559 0.451 0.5071
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0056 0.0099 0.0098
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0097 0.0219 0.0218
Loa Loa (eye worm) hypothetical protein 0.0163 0.0413 0.0469
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0055 0.0096 0.0182
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0103 0.0237 0.0507
Trichomonas vaginalis glutathione reductase, putative 0.004 0.0053 0.014
Schistosoma mansoni cpg binding protein 0.0092 0.0206 0.0231
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0097 0.0221 0.025
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0437 0.1217 0.1216
Treponema pallidum NADH oxidase 0.004 0.0053 0.0241
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0047 0.0087
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.0109 0.0108
Brugia malayi Pyruvate kinase, M2 isozyme 0.0105 0.0243 0.0276
Echinococcus multilocularis g-protein coupled receptor 0.0437 0.1217 0.1216
Brugia malayi PAS domain containing protein 0.0048 0.0076 0.0086
Loa Loa (eye worm) hypothetical protein 0.0076 0.0159 0.018
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0097 0.0221 0.025
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0041 0.0055 0.0054
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0186 0.048 0.1088
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0059 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0158 0.0398 0.0452
Trichomonas vaginalis glucosylceramidase, putative 0.0213 0.0561 0.2133
Mycobacterium ulcerans flavoprotein disulfide reductase 0.004 0.0053 0.0192
Schistosoma mansoni neuropeptide receptor 0.0437 0.1217 0.1367
Echinococcus granulosus high affinity choline transporter 1 0.037 0.1021 0.1147
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0078 0.0163 0.0185
Loa Loa (eye worm) pyruvate kinase 0.0105 0.0243 0.0276
Giardia lamblia Hypothetical protein 0.0186 0.048 0.2553

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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