Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | histone deacetylase hda2 | 0.1158 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0661 | 0.0364 | 0.0378 |
Plasmodium vivax | histone deacetylase 2, putative | 0.1139 | 0.9636 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1027 | 0.7465 | 0.7746 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0912 | 0.5229 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.1139 | 0.9636 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0912 | 0.5229 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.1027 | 0.7465 | 0.4686 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0912 | 0.5229 | 0.5426 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1027 | 0.7465 | 0.4686 |
Echinococcus granulosus | histone deacetylase 7 | 0.1139 | 0.9636 | 0.9237 |
Leishmania major | histone deacetylase, putative | 0.1139 | 0.9636 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1027 | 0.7465 | 0.7746 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.1139 | 0.9636 | 1 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.1139 | 0.9636 | 1 |
Echinococcus granulosus | histone deacetylase | 0.1139 | 0.9636 | 0.9237 |
Trypanosoma brucei | histone deacetylase 4 | 0.1139 | 0.9636 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0912 | 0.5229 | 0.5426 |
Echinococcus granulosus | acetylcholinesterase | 0.1027 | 0.7465 | 0.4686 |
Entamoeba histolytica | histone deacetylase, putative | 0.0912 | 0.5229 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0912 | 0.5229 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1139 | 0.9636 | 1 |
Loa Loa (eye worm) | histone deacetylase | 0.1139 | 0.9636 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1027 | 0.7465 | 0.7746 |
Brugia malayi | Histone deacetylase family protein | 0.1139 | 0.9636 | 1 |
Giardia lamblia | Histone deacetylase | 0.0912 | 0.5229 | 0.5 |
Echinococcus multilocularis | histone deacetylase | 0.1139 | 0.9636 | 0.9237 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1027 | 0.7465 | 0.4686 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1139 | 0.9636 | 1 |
Trypanosoma brucei | histone deacetylase 3 | 0.1139 | 0.9636 | 1 |
Brugia malayi | histone deacetylase 11 | 0.1025 | 0.7435 | 0.5006 |
Echinococcus multilocularis | histone deacetylase 7 | 0.1139 | 0.9636 | 0.9237 |
Loa Loa (eye worm) | hypothetical protein | 0.0912 | 0.5229 | 0.5426 |
Echinococcus multilocularis | acetylcholinesterase | 0.1027 | 0.7465 | 0.4686 |
Brugia malayi | Carboxylesterase family protein | 0.1027 | 0.7465 | 0.5073 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.1025 | 0.7435 | 0.7716 |
Trypanosoma brucei | histone deacetylase, putative | 0.1139 | 0.9636 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1139 | 0.9636 | 0.9237 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1139 | 0.9636 | 0.9237 |
Brugia malayi | Carboxylesterase family protein | 0.1027 | 0.7465 | 0.5073 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0912 | 0.5229 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0912 | 0.5229 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.1027 | 0.7465 | 0.4686 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.1025 | 0.7435 | 0.5006 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0912 | 0.5229 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0912 | 0.5229 | 0.5 |
Plasmodium falciparum | histone deacetylase, putative | 0.1139 | 0.9636 | 1 |
Plasmodium vivax | histone deacetylase, putative | 0.1025 | 0.7435 | 0.5006 |
Plasmodium vivax | histone deacetylase, putative | 0.1139 | 0.9636 | 1 |
Plasmodium falciparum | histone deacetylase 2 | 0.1139 | 0.9636 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.1139 | 0.9636 | 0.9237 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0912 | 0.5229 | 0.5 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.1139 | 0.9636 | 0.9237 |
Brugia malayi | Histone deacetylase family protein | 0.1139 | 0.9636 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1158 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.1139 | 0.9636 | 0.9237 |
Echinococcus granulosus | acetylcholinesterase | 0.1027 | 0.7465 | 0.4686 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.1139 | 0.9636 | 0.9237 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1139 | 0.9636 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0912 | 0.5229 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.1027 | 0.7465 | 0.7746 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.