Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.082 | 0.0913 | 0.1133 |
Onchocerca volvulus | 0.082 | 0.0913 | 0.5 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0573 | 0.0043 | 1 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.235 | 0.6296 | 0.6279 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0573 | 0.0043 | 0.5 |
Toxoplasma gondii | AGC kinase | 0.0573 | 0.0043 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2755 | 0.7721 | 1 |
Schistosoma mansoni | atypical protein kinase C | 0.0978 | 0.1469 | 0.1432 |
Schistosoma mansoni | serine/threonine protein kinase | 0.3403 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1225 | 0.2339 | 0.2989 |
Trichomonas vaginalis | AGC family protein kinase | 0.0573 | 0.0043 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.2998 | 0.8575 | 0.8568 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.235 | 0.6296 | 0.6279 |
Brugia malayi | Protein kinase c protein 2 | 0.2842 | 0.8028 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0573 | 0.0043 | 0.5 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.2437 | 0.6602 | 0.8543 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.1053 | 0.1732 | 0.2199 |
Echinococcus granulosus | protein kinase c epsilon type | 0.1053 | 0.1732 | 0.1696 |
Trichomonas vaginalis | AGC family protein kinase | 0.0573 | 0.0043 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0573 | 0.0043 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0573 | 0.0043 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0573 | 0.0043 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0573 | 0.0043 | 0.5 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.235 | 0.6296 | 0.6279 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.1053 | 0.1732 | 0.1696 |
Trichomonas vaginalis | AGC family protein kinase | 0.0573 | 0.0043 | 1 |
Echinococcus granulosus | protein kinase C gamma type | 0.2998 | 0.8575 | 0.8568 |
Echinococcus multilocularis | protein kinase c iota type | 0.0978 | 0.1469 | 0.1432 |
Loa Loa (eye worm) | hypothetical protein | 0.082 | 0.0913 | 0.1133 |
Loa Loa (eye worm) | hypothetical protein | 0.082 | 0.0913 | 0.1133 |
Entamoeba histolytica | protein kinase, putative | 0.0573 | 0.0043 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0573 | 0.0043 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0573 | 0.0043 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.0978 | 0.1469 | 0.1432 |
Brugia malayi | protein kinase C II. | 0.1053 | 0.1732 | 0.2115 |
Trichomonas vaginalis | AGC family protein kinase | 0.0573 | 0.0043 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1393 | 0.2929 | 0.3759 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.3403 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0573 | 0.0043 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.235 | 0.6296 | 0.8143 |
Schistosoma mansoni | serine/threonine protein kinase | 0.3403 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0573 | 0.0043 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1053 | 0.1732 | 0.1696 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.