Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0202 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0202 | 1 | 1 |
Schistosoma mansoni | glutamate receptor kainate | 0.0109 | 0.3539 | 0.3539 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0107 | 0.3377 | 0.3377 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0202 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0095 | 0.2583 | 0.2583 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0202 | 1 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0095 | 0.2583 | 0.2583 |
Brugia malayi | hypothetical protein | 0.0107 | 0.3377 | 0.1071 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0202 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.3377 | 0.1071 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0202 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0095 | 0.2583 | 0.2583 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0202 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0202 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0107 | 0.3377 | 0.3377 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0202 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0202 | 1 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0095 | 0.2583 | 0.2583 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0202 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0202 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0202 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0202 | 1 | 1 |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.0078 | 0.1399 | 0.1399 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0095 | 0.2583 | 0.2583 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0202 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0202 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0202 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0118 | 0.4183 | 0.4183 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0078 | 0.1399 | 0.1399 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.3377 | 0.1071 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0107 | 0.3377 | 0.3377 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0202 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0202 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0095 | 0.2583 | 0.2583 |
Echinococcus multilocularis | NMDA receptor | 0.0078 | 0.1399 | 0.1399 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0107 | 0.3377 | 0.3377 |
Schistosoma mansoni | nuclear receptor | 0.0095 | 0.2583 | 0.2583 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0095 | 0.2583 | 0.2583 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0095 | 0.2583 | 0.2583 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0202 | 1 | 1 |
Onchocerca volvulus | 0.0202 | 1 | 1 | |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0202 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0118 | 0.4183 | 0.4183 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0202 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0202 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0095 | 0.2583 | 0.2583 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0095 | 0.2583 | 0.2583 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0202 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 1 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0095 | 0.2583 | 0.2583 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0202 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0202 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0107 | 0.3377 | 0.1071 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0118 | 0.4183 | 0.4183 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0095 | 0.2583 | 0.2583 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0202 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0202 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0202 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.3377 | 0.1071 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0202 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0202 | 1 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0095 | 0.2583 | 0.2583 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0095 | 0.2583 | 0.2583 |
Brugia malayi | hypothetical protein | 0.0107 | 0.3377 | 0.1071 |
Schistosoma mansoni | glutamate receptor kainate | 0.0109 | 0.3539 | 0.3539 |
Schistosoma mansoni | thyroid hormone receptor | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.3377 | 0.1071 |
Echinococcus granulosus | FTZ F1 alpha | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.3377 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0202 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0202 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0107 | 0.3377 | 0.1071 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0202 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0095 | 0.2583 | 0.2583 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0118 | 0.4183 | 0.4183 |
Schistosoma mansoni | nuclear hormone receptor | 0.0095 | 0.2583 | 0.2583 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0202 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0095 | 0.2583 | 0.2583 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0107 | 0.3377 | 0.1071 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0202 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0118 | 0.4183 | 0.4183 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0202 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0202 | 1 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0095 | 0.2583 | 0.2583 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0202 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0202 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0202 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0202 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0202 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0202 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0202 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0107 | 0.3377 | 0.1071 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0202 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0202 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0202 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0202 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0202 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.0078 | 0.1399 | 0.1399 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.0078 | 0.1399 | 0.1399 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0118 | 0.4183 | 0.4183 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0095 | 0.2583 | 0.2583 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0202 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.