Detailed information for compound 87558

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 520.438 | Formula: C27H22Na2O8
  • H donors: 0 H acceptors: 5 LogP: 5.91 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCc1cc(C(=O)C)c(cc1OCCCOc1ccc2c(c1)oc1c(c2=O)cc(cc1)C(=O)[O-])[O-].[Na+].[Na+]
  • InChi: 1S/C27H24O8.2Na/c1-3-16-11-20(15(2)28)22(29)14-24(16)34-10-4-9-33-18-6-7-19-25(13-18)35-23-8-5-17(27(31)32)12-21(23)26(19)30;;/h5-8,11-14,29H,3-4,9-10H2,1-2H3,(H,31,32);;/q;2*+1/p-2
  • InChiKey: GZBGOBTXLAOZHD-UHFFFAOYSA-L  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens leukotriene B4 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0344 0.0481
Mycobacterium leprae Probable lipase LipE 0.015 0.1141 0.338
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0069 0.0216
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0044 0.005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0017 0.0016 0.0014
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0568 0.0794
Schistosoma mansoni rab6-interacting 0.002 0.0039 0.0047
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0287 0.0401
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Mycobacterium ulcerans hypothetical protein 0.015 0.1141 0.4598
Onchocerca volvulus 0.015 0.1141 0.1137
Toxoplasma gondii ABC1 family protein 0.015 0.1141 0.4622
Schistosoma mansoni intermediate filament proteins 0.0027 0.0097 0.013
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0008 0.0011
Trypanosoma brucei heat shock protein, putative 0.0045 0.0251 0.1044
Brugia malayi hypothetical protein 0.002 0.0039 0.0039
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0006 0.0004
Trichomonas vaginalis glutathione reductase, putative 0.0056 0.0348 0.0343
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0374 0.1565
Trypanosoma brucei heat shock protein, putative 0.0045 0.0251 0.1044
Loa Loa (eye worm) thioredoxin reductase 0.0162 0.1242 0.1416
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0069 0.026
Loa Loa (eye worm) hypothetical protein 0.0051 0.0301 0.0343
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0017 0.0016 0.0047
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0044 0.0055
Onchocerca volvulus 0.0082 0.0568 0.0564
Schistosoma mansoni endoplasmin 0.0045 0.0251 0.0346
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0629 0.0712
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.015 0.1141 0.4598
Brugia malayi TAR-binding protein 0.0325 0.2613 0.2975
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0363 0.0508
Brugia malayi Glycosyl hydrolases family 31 protein 0.0336 0.2711 0.3087
Leishmania major heat shock protein, putative 0.003 0.0124 0.0486
Onchocerca volvulus 0.002 0.0039 0.0034
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0959 0.7972 1
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0228 0.0223
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0344 0.0481
Trypanosoma cruzi Heat shock protein 83, putative 0.0045 0.0251 0.1044
Trichomonas vaginalis endoplasmin, putative 0.0032 0.0148 0.0143
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0069 0.008
Trichomonas vaginalis maltase-glucoamylase, putative 0.0028 0.0108 0.0103
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0006 0.0007
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0238 0.0333
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0044 0.0045
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0348 0.4101
Echinococcus granulosus tumor protein p63 0.0346 0.2793 0.3914
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0525 0.0733
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0044 0.0045
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0044 0.0039
Loa Loa (eye worm) endoplasmin 0.0045 0.0251 0.0286
Schistosoma mansoni aldehyde dehydrogenase 0.0307 0.2463 0.3447
Mycobacterium ulcerans aldehyde dehydrogenase 0.0307 0.2463 1
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0164 0.0182
Entamoeba histolytica deoxycytidyl transferase, putative 0.0059 0.0374 0.158
Brugia malayi hypothetical protein 0.002 0.0039 0.0039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Schistosoma mansoni hypothetical protein 0.0036 0.0174 0.0237
Schistosoma mansoni aldehyde dehydrogenase 0.0017 0.0016 0.0015
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0008 0.0004
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0044 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0238 0.0233
Schistosoma mansoni patched 1 0.0043 0.0238 0.0327
Brugia malayi beta-lactamase family protein 0.015 0.1141 0.1296
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0525 0.2224
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0059 0.0374 0.1503
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0044
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.2364 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0056 0.0348 0.2636
Plasmodium vivax JmjC domain containing protein 0.0016 0.0006 0.0008
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0039 0.0054
Echinococcus multilocularis geminin 0.086 0.7135 0.9975
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0044 0.005
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0044 0.0055
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0629 0.0882
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0056 0.0348 0.0391
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0008 0.0011
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0374 0.1565
Schistosoma mansoni heat shock protein 0.0045 0.0251 0.0346
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0186 0.0774
Toxoplasma gondii aldehyde dehydrogenase 0.0307 0.2463 1
Trypanosoma brucei heat shock protein, putative 0.0045 0.0251 0.1044
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0411 0.3345 0.4192
Plasmodium vivax endoplasmin, putative 0.0045 0.0251 0.1894
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0018
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0042 0.0228 0.0637
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0348 0.1453
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0186 0.0206
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0006 0.0004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0348 0.4101
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.015 0.1141 0.1296
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0228 0.0223
Trypanosoma brucei heat shock protein, putative 0.0045 0.0251 0.1044
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0005 0.0005
Echinococcus multilocularis traf and tnf receptor associated protein 0.0016 0.0005 0.0007
Mycobacterium tuberculosis Conserved protein 0.015 0.1141 0.1426
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0021 0.0029
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0363 0.0509
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0091 0.0644 0.0734
Echinococcus granulosus Niemann Pick C1 protein 0.0144 0.1087 0.1523
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0039 0.0054
Schistosoma mansoni cpg binding protein 0.0031 0.0131 0.0177
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0069 0.0159
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0017 0.0016 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0044 0.0045
Trypanosoma brucei heat shock protein 84, putative 0.003 0.0124 0.0507
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0101 0.0722 0.0824
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0044 0.0055
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0525 0.6288
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.0029 0.0184
Schistosoma mansoni loxhd1 0.002 0.0039 0.0047
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0041 0.0222 0.0248
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.005
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0186 0.0774
Loa Loa (eye worm) hypothetical protein 0.0151 0.1147 0.1307
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0056 0.0348 0.1453
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0287 0.0396
Schistosoma mansoni cpg binding protein 0.0032 0.0146 0.0198
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0348 0.1395
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0108 0.0437
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0044 0.0045
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.0862 0.1205
Mycobacterium tuberculosis Probable oxidoreductase 0.0411 0.3345 0.4192
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0044 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0029 0.0101
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0568 0.0643
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0186 0.026
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0363 0.1421
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0039 0.026
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0411 0.3345 0.4192
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0108 0.0103
Leishmania major trypanothione reductase 0.0162 0.1242 0.5035
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.015 0.1141 0.1426
Loa Loa (eye worm) heat shock protein 90 0.0045 0.0251 0.0286
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0017 0.0016 0.0045
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0017 0.0016 0.0047
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0287 0.0396
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0044 0.0055
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0075 0.0503 0.2027
Toxoplasma gondii heat shock protein HSP90 0.0045 0.0251 0.1002
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0287 0.0396
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.108 0.1349
Brugia malayi aldehyde dehydrogenase 0.0017 0.0016 0.0013
Trypanosoma brucei heat shock protein, putative 0.0045 0.0251 0.1044
Onchocerca volvulus 0.002 0.0039 0.0034
Schistosoma mansoni hypothetical protein 0.0042 0.0225 0.0308
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0503 0.0498
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0293 0.2343 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0044 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0044 0.0045
Schistosoma mansoni rab6-interacting 0.002 0.0039 0.0047
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0017 0.0016 0.0045
Loa Loa (eye worm) hypothetical protein 0.0082 0.0568 0.0648
Loa Loa (eye worm) hypothetical protein 0.0049 0.0287 0.0327
Onchocerca volvulus 0.0049 0.0287 0.0282
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0029 0.0101
Loa Loa (eye worm) hypothetical protein 0.0043 0.0238 0.0271
Loa Loa (eye worm) hypothetical protein 0.015 0.1141 0.1301
Echinococcus multilocularis neutral alpha glucosidase AB 0.0075 0.0503 0.0703
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0525 0.0735
Echinococcus multilocularis dna polymerase kappa 0.0059 0.0374 0.0523
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0044 0.0062
Echinococcus multilocularis tumor protein p63 0.0346 0.2793 0.3904
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0503 0.2112
Brugia malayi Muscleblind-like protein 0.0151 0.1147 0.1303
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0069 0.0273
Loa Loa (eye worm) hypothetical protein 0.0152 0.1154 0.1316
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0186 0.0767
Schistosoma mansoni tar DNA-binding protein 0.0325 0.2613 0.3658
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0152 0.1154 0.1612
Echinococcus multilocularis lysosomal alpha glucosidase 0.0336 0.2711 0.379
Trypanosoma brucei trypanothione reductase 0.0162 0.1242 0.5245
Brugia malayi serine/threonine-protein kinase plk-2 0.0091 0.0644 0.0729
Leishmania major DNA polymerase kappa, putative 0.0059 0.0374 0.1503
Loa Loa (eye worm) glutaminase 2 0.0291 0.2328 0.2654
Schistosoma mansoni ap endonuclease 0.0077 0.0525 0.0729
Leishmania major DNA polymerase eta, putative 0.0059 0.0374 0.1503
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0044 0.0062
Schistosoma mansoni kinase 0.0046 0.0265 0.0365
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0287 0.0402
Schistosoma mansoni nuclear hormone receptor 0.002 0.0044 0.0055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.2343 0.2339
Brugia malayi beta-lactamase family protein 0.015 0.1141 0.1296
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.0363 0.045
Echinococcus granulosus muscleblind protein 0.0151 0.1147 0.1607
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1052 0.4439
Echinococcus multilocularis GPCR, family 2 0.0016 0.0008 0.0011
Mycobacterium leprae conserved hypothetical protein 0.015 0.1141 0.338
Trichomonas vaginalis D-aminoacylase, putative 0.015 0.1141 0.1137
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0168 0.0234
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0385 0.0539
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0007
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0385 0.0533
Toxoplasma gondii NADPH-glutathione reductase 0.0056 0.0348 0.1395
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0017 0.0016 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0644 0.0639
Trypanosoma cruzi hypothetical protein, conserved 0.015 0.1141 0.4815
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0044 0.005
Echinococcus multilocularis inositol monophosphatase 1 0.0113 0.0825 0.1154
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0006 0.0001
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0008 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0644 0.0896
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0056 0.0348 0.1357
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0032 0.0113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0044 0.005
Trichomonas vaginalis mercuric reductase, putative 0.0056 0.0348 0.0343
Schistosoma mansoni lipoxygenase 0.0117 0.0862 0.1202
Mycobacterium tuberculosis Putative ferredoxin reductase 0.037 0.2996 0.3755
Schistosoma mansoni hypothetical protein 0.0034 0.0164 0.0224
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0028 0.0108 0.0441
Plasmodium vivax hypothetical protein, conserved 0.015 0.1141 0.8734
Plasmodium vivax ataxin-2 like protein, putative 0.0078 0.053 0.4034
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0044 0.0045
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0033
Echinococcus multilocularis synaptojanin 1 0.0016 0.0005 0.0007
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0182 0.1411 0.1609
Plasmodium falciparum thioredoxin reductase 0.0162 0.1242 0.9514
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Toxoplasma gondii hypothetical protein 0.0048 0.0275 0.1099
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0006 0.0008
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.003 0.0124 0.012
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0299 0.0336
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0525 0.0653
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0629 0.088
Loa Loa (eye worm) hypothetical protein 0.0053 0.032 0.0365
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Echinococcus granulosus cpg binding protein 0.0032 0.0146 0.0204
Trypanosoma brucei DNA polymerase eta, putative 0.0059 0.0374 0.1565
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0186 0.026
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0056 0.0348 0.0487
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.0029 0.0184
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0108 0.0437
Loa Loa (eye worm) hypothetical protein 0.015 0.1141 0.1301
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0017 0.0016 0.0047
Schistosoma mansoni jumonji domain containing protein 0.0059 0.037 0.0512
Toxoplasma gondii thioredoxin reductase 0.0162 0.1242 0.5035
Treponema pallidum heat shock protein 90 0.0042 0.0228 0.0955
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0017 0.0016 0.0014
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0251 0.1044
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.0251 0.1044
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0307 0.2463 0.3085
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0006 0.0001
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.033 0.0377
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0348 0.1453
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0044
Brugia malayi hypothetical protein 0.0078 0.053 0.0599
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0017 0.0016 0.0013
Schistosoma mansoni ap endonuclease 0.0077 0.0525 0.0729
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0069 0.026
Schistosoma mansoni tar DNA-binding protein 0.0325 0.2613 0.3658
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0017 0.0016 0.0045
Echinococcus granulosus thioredoxin glutathione reductase 0.0164 0.1255 0.1759
Brugia malayi glutaminase DH11.1 0.0291 0.2328 0.2649
Trypanosoma brucei polo-like protein kinase 0.0091 0.0644 0.2708
Loa Loa (eye worm) TAR-binding protein 0.0325 0.2613 0.2979
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0017 0.0016 0.0022
Mycobacterium tuberculosis Conserved hypothetical protein 0.0059 0.0374 0.0464
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0629 0.0876
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0005 0.0005
Trypanosoma cruzi polo-like protein kinase, putative 0.0091 0.0644 0.2708
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0008 0.0004
Echinococcus multilocularis Niemann Pick C1 protein 0.0144 0.1087 0.1519
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0075 0.0503 0.0574
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0348 0.1453
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.005
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0029 0.0101
Mycobacterium tuberculosis Probable lipase LipD 0.015 0.1141 0.1426
Schistosoma mansoni lamin 0.0027 0.0097 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0177 0.1369 0.1365
Schistosoma mansoni hypothetical protein 0.0042 0.0225 0.0308
Schistosoma mansoni hypothetical protein 0.086 0.7135 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Loa Loa (eye worm) hypothetical protein 0.015 0.1141 0.1301
Loa Loa (eye worm) hypothetical protein 0.015 0.1141 0.1301
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Brugia malayi jmjC domain containing protein 0.0061 0.0385 0.0434
Leishmania major DNA polymerase eta, putative 0.0018 0.0029 0.0097
Echinococcus granulosus heat shock protein 90 0.0045 0.0251 0.0352
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0568 0.0796
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0525 0.3997
Mycobacterium tuberculosis Probable hydrolase 0.015 0.1141 0.1426
Trichomonas vaginalis DNA polymerase eta, putative 0.0059 0.0374 0.037
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0113 0.0825 0.3509
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0017 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0056 0.0348 0.1395
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0644 0.0639
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.037 0.2996 0.3755
Trypanosoma brucei heat shock protein, putative 0.0045 0.0251 0.1044
Echinococcus multilocularis RUN 0.002 0.0039 0.0054
Trichomonas vaginalis heat shock protein, putative 0.0045 0.0251 0.0247
Schistosoma mansoni tar DNA-binding protein 0.0325 0.2613 0.3658
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0069 0.0216
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0374 0.1464
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0017 0.0016 0.0047
Entamoeba histolytica hypothetical protein 0.0036 0.0174 0.0724
Brugia malayi nuclear receptor NHR-88 0.002 0.0044 0.0045
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0503 0.0498
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Echinococcus multilocularis protein dispatched 1 0.0049 0.0289 0.0404
Entamoeba histolytica 90 kDa heat shock protein, putative 0.003 0.0124 0.0511
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0186 0.026
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0503 0.0498
Brugia malayi Thioredoxin reductase 0.0162 0.1242 0.1412
Brugia malayi follicle stimulating hormone receptor 0.0474 0.3877 0.4417
Trichomonas vaginalis penicillin-binding protein, putative 0.015 0.1141 0.1137
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0348 0.1453
Entamoeba histolytica hypothetical protein 0.0023 0.0069 0.0273
Echinococcus granulosus expressed conserved protein 0.0094 0.0671 0.094
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0307 0.2463 1
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0017 0.0016 0.0047
Echinococcus granulosus synaptojanin 1 0.0016 0.0005 0.0007
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0186 0.0767
Schistosoma mansoni aldehyde dehydrogenase 0.0017 0.0016 0.0015
Echinococcus multilocularis heat shock protein 90 0.0045 0.0251 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0044 0.0062
Trypanosoma cruzi polo-like protein kinase, putative 0.0091 0.0644 0.2708
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0017 0.0016 0.0011
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0039 0.0054
Leishmania major alpha glucosidase II subunit, putative 0.0075 0.0503 0.2027
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0348 0.1453
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0044 0.0062
Giardia lamblia Heat shock protein HSP 90-alpha 0.0038 0.0197 0.082
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.1052 0.4439
Mycobacterium tuberculosis Conserved protein 0.015 0.1141 0.1426
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0113 0.0825 0.3308
Schistosoma mansoni aldehyde dehydrogenase 0.0017 0.0016 0.0015
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0021 0.0029
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0525 0.2224
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0017 0.0016 0.0022
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0041 0.0222 0.0248
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.037 0.0519
Onchocerca volvulus 0.015 0.1141 0.1137
Brugia malayi CXXC zinc finger family protein 0.0031 0.0131 0.0144
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0044 0.0062
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0044 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0044 0.0045
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0174 0.0243
Entamoeba histolytica hypothetical protein 0.0036 0.0174 0.0724
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0152 0.1154 0.1614
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0017 0.0016 0.0022
Entamoeba histolytica serine/threonine protein kinase, putative 0.0091 0.0644 0.2732
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0017 0.0016 0.0047
Leishmania major DNA damage repair protein, putative 0.0018 0.0029 0.0097
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0029 0.0101
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0325 0.2613 0.2979
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0644 0.0639
Onchocerca volvulus 0.0031 0.0131 0.0126
Plasmodium falciparum thioredoxin reductase 0.0056 0.0348 0.2636
Mycobacterium ulcerans hypothetical protein 0.0155 0.1185 0.478
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0016 0.0005 0.0007
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0059 0.0374 0.0523
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0006 0.0001
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0017 0.0016 0.0047
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0467 0.0648
Plasmodium vivax thioredoxin reductase, putative 0.0162 0.1242 0.9514
Giardia lamblia Kinase, PLK 0.0091 0.0644 0.2732
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0017 0.0016 0.0047
Trypanosoma brucei glucosidase, putative 0.0075 0.0503 0.2112
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0044 0.0045
Echinococcus multilocularis musashi 0.0027 0.0097 0.0136
Mycobacterium ulcerans esterase/lipase LipP 0.015 0.1141 0.4598
Loa Loa (eye worm) hypothetical protein 0.005 0.0299 0.0341
Brugia malayi beta-lactamase 0.015 0.1141 0.1296
Plasmodium vivax heat shock protein 90, putative 0.003 0.0124 0.0919
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0009
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0017 0.0016 0.0047
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0029 0.0101
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0385 0.0439
Entamoeba histolytica hypothetical protein 0.0036 0.0174 0.0724
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0056 0.0348 0.1453
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0644 0.0639
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0093 0.0088
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0006 0.0001
Loa Loa (eye worm) hypothetical protein 0.0078 0.053 0.0604
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0307 0.2463 0.3452
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0005 0.0005
Schistosoma mansoni thyroid hormone receptor 0.002 0.0044 0.0055
Trypanosoma brucei Heat shock protein 83, putative 0.0045 0.0251 0.1044
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0168 0.0235
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0006 0.0008
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0017 0.0016 0.0047
Echinococcus multilocularis muscleblind protein 0.0151 0.1147 0.1603
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0862 0.7153 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0108 0.0103
Leishmania major hypothetical protein, conserved 0.015 0.1141 0.4622
Schistosoma mansoni tar DNA-binding protein 0.0325 0.2613 0.3658
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0113 0.0825 1
Trypanosoma cruzi heat shock protein 90, putative 0.0045 0.0251 0.1044
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0503 0.0498
Trypanosoma cruzi heat shock protein 90, putative 0.0038 0.0197 0.0813
Brugia malayi Aldehyde dehydrogenase protein 4 0.0017 0.0016 0.0013
Giardia lamblia NADH oxidase lateral transfer candidate 0.0056 0.0348 0.1467
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0101 0.0725 0.2132
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0044 0.0062
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0044 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Mycobacterium ulcerans aldehyde dehydrogenase 0.0307 0.2463 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0503 0.0498
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0097 0.0106
Echinococcus granulosus RUN 0.002 0.0039 0.0054
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0186 0.0254
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0044 0.0045
Brugia malayi hypothetical protein 0.0036 0.0174 0.0193
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0525 0.2203
Echinococcus granulosus endoplasmin 0.0042 0.0228 0.032
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0038 0.0197 0.0276
Toxoplasma gondii exonuclease III APE 0.0077 0.0525 0.2115
Toxoplasma gondii heat shock protein 75, putative 0.003 0.0124 0.0486
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.015 0.1141 0.1301
Onchocerca volvulus 0.0027 0.0097 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.0722 0.1013
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0016 0.0005 0.0005
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0042 0.0228 0.028
Echinococcus multilocularis heat shock protein 90 0.0038 0.0197 0.0275
Mycobacterium ulcerans aldehyde dehydrogenase 0.0307 0.2463 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0039 0.0054
Schistosoma mansoni aldehyde dehydrogenase 0.0017 0.0016 0.0015
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0113 0.0825 0.0821
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.037 0.2996 0.8953
Schistosoma mansoni survival motor neuron protein 0.005 0.0299 0.0413
Plasmodium vivax glutathione reductase, putative 0.0162 0.1242 0.9514
Echinococcus granulosus dna polymerase kappa 0.0059 0.0374 0.0524
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0224 0.0927
Brugia malayi MH2 domain containing protein 0.0119 0.0882 0.1001
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0108 0.0103
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0017 0.0016 0.0022
Brugia malayi polk-prov protein 0.0018 0.0029 0.0027
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0006 0.0008
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0882 0.1006
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0131 0.015
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0017 0.0016 0.0022
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0017 0.0016 0.0047
Echinococcus multilocularis lysosomal alpha glucosidase 0.0336 0.2711 0.379
Trypanosoma cruzi DNA polymerase eta, putative 0.0059 0.0374 0.1565
Echinococcus multilocularis heat shock protein 0.0045 0.0251 0.0351
Trichomonas vaginalis esterase, putative 0.015 0.1141 0.1137
Leishmania major hypothetical protein, conserved 0.0078 0.053 0.2135
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0525 0.2203
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0374 0.1464
Leishmania major mitochondrial DNA polymerase beta 0.0295 0.2364 0.9599
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0251 0.1044
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0005 0.0007
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0344 0.0482
Trypanosoma brucei unspecified product 0.0041 0.0219 0.0907
Loa Loa (eye worm) doublecortin family protein 0.002 0.0039 0.0044
Trichomonas vaginalis glutaminase, putative 0.0291 0.2328 0.2324
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Echinococcus multilocularis beta LACTamase domain containing family member 0.015 0.1141 0.1595
Loa Loa (eye worm) hypothetical protein 0.0247 0.1961 0.2235
Echinococcus granulosus inositol monophosphatase 1 0.0113 0.0825 0.1156
Brugia malayi jmjC domain containing protein 0.0016 0.0006 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0028 0.0108 0.0118
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0503 0.0498
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.0251 0.1044
Plasmodium vivax heat shock protein, putative 0.017 0.1306 1
Brugia malayi Endoplasmin precursor 0.0045 0.0251 0.0281
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0348 0.1453
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0044 0.0045
Echinococcus multilocularis expressed conserved protein 0.0094 0.0671 0.0938
Loa Loa (eye worm) MBCTL1 0.0056 0.0344 0.0392
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0056 0.0348 0.1357
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.0722 0.101
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0006 0.0008
Mycobacterium ulcerans hypothetical protein 0.0018 0.0029 0.0053
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0091 0.0644 0.2599
Schistosoma mansoni heat shock protein 0.003 0.0124 0.0168
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0209 0.1634 0.2291
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0503 0.2112
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0017 0.0016 0.0047
Trypanosoma brucei PAB1-binding protein , putative 0.0078 0.053 0.2224
Brugia malayi hypothetical protein 0.0247 0.1961 0.2231
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0044 0.005
Brugia malayi ecdysteroid receptor 0.002 0.0044 0.0045
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0006 0.0004
Plasmodium falciparum heat shock protein 90, putative 0.017 0.1306 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.053 0.2224
Echinococcus multilocularis tar DNA binding protein 0.0325 0.2613 0.3653
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.0363 0.0503
Treponema pallidum gamma-glutamyl phosphate reductase 0.0017 0.0016 0.0047
Treponema pallidum fructose-bisphosphate aldolase 0.0293 0.2343 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0238 0.0332
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0299 0.0341
Entamoeba histolytica hypothetical protein 0.0036 0.0174 0.0724
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.053 0.2224
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0017 0.0016 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.037 0.0518
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.003 0.0124 0.0174
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0152 0.1154 0.1612
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0108 0.0103
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0348 0.1453
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.0374 0.0421
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0101 0.0725 0.0904
Echinococcus granulosus traf and tnf receptor associated protein 0.0016 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0186 0.0212
Toxoplasma gondii LsmAD domain-containing protein 0.0078 0.053 0.2135
Brugia malayi RNA binding protein 0.0325 0.2613 0.2975
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0152 0.1154 0.4677
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0017 0.0016 0.0014
Schistosoma mansoni inositol monophosphatase 0.0113 0.0825 0.115
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.0251 0.1054
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Brugia malayi Doublecortin family protein 0.002 0.0039 0.0039
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.037 0.2996 0.3755
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0017 0.0016 0.0015
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0069 0.0491
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0006 0.0008
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0044 0.0039
Plasmodium falciparum endoplasmin, putative 0.0032 0.0148 0.1098
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0348 0.1453
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0017 0.0016 0.0047
Trichomonas vaginalis inositol monophosphatase, putative 0.0113 0.0825 0.0821
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0219 0.0907
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.108 0.4347
Giardia lamblia Grp94/Hsp90 0.0042 0.0228 0.0955
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.2343 0.2339
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0017 0.0016 0.0018
Schistosoma mansoni alpha-glucosidase 0.0289 0.2316 0.3241
Leishmania major glycosyl hydrolase-like protein 0.0028 0.0108 0.0419
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.037 0.0518
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0186 0.0254
Echinococcus multilocularis neutral sphingomyelinase 0.0016 0.0005 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.015 0.1141 0.4815
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0113 0.0825 0.3477
Brugia malayi intermediate filament protein 0.0027 0.0097 0.0106
Schistosoma mansoni hypothetical protein 0.0313 0.2519 0.3525
Mycobacterium tuberculosis Probable conserved lipoprotein 0.015 0.1141 0.1426
Onchocerca volvulus 0.015 0.1141 0.1137
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0525 0.0598
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0525 0.2224
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0028 0.0108 0.0103
Trypanosoma cruzi DNA polymerase eta, putative 0.0018 0.0029 0.0101
Trypanosoma brucei glycosyl hydrolase-like protein 0.0028 0.0108 0.0437
Echinococcus granulosus geminin 0.086 0.7135 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0299 0.0336
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0017 0.0016 0.0047
Brugia malayi Inositol-1 0.0113 0.0825 0.0936
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0348 0.1395
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0182 0.1411 0.1604
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0006 0.0004
Brugia malayi mbt repeat family protein 0.0049 0.0287 0.0322
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0525 0.052
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0363 0.1421
Schistosoma mansoni heat shock protein 0.0045 0.0251 0.0346
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.0251 0.1054
Echinococcus granulosus dnaJ subfamily B 0.0435 0.3546 0.4969
Brugia malayi glutathione reductase 0.0162 0.1242 0.1412
Echinococcus granulosus intermediate filament protein 0.0027 0.0097 0.0137
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0108 0.0103
Loa Loa (eye worm) hypothetical protein 0.015 0.1141 0.1301
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0017 0.0016 0.0011
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0108 0.0103
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0091 0.0644 0.09
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0017 0.0016 0.0047
Giardia lamblia DINP protein human, muc B family 0.0059 0.0374 0.158
Onchocerca volvulus 0.0152 0.1154 0.115
Giardia lamblia DNA damage repair protein 0.0018 0.0029 0.0102
Loa Loa (eye worm) hypothetical protein 0.0028 0.0108 0.0123
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0162 0.1242 0.1553
Echinococcus granulosus lysosomal alpha glucosidase 0.0336 0.2711 0.38
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0017 0.0016 0.0047
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Brugia malayi hypothetical protein 0.005 0.0297 0.0333
Echinococcus granulosus neutral alpha glucosidase AB 0.0075 0.0503 0.0705
Echinococcus granulosus lamin dm0 0.0027 0.0097 0.0137
Trypanosoma cruzi heat shock protein 85, putative 0.0038 0.0197 0.0813
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0059 0.0374 0.0524
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0644 0.0639
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0152 0.1154 0.1612
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0113 0.0825 0.3337
Trichomonas vaginalis set domain proteins, putative 0.12 1 1
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0344 0.0387
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0186 0.0767
Trypanosoma brucei unspecified product 0.0059 0.0374 0.1565
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0629 0.0882
Schistosoma mansoni thyroid hormone receptor 0.002 0.0044 0.0055
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0409 0.1643
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0044 0.0045
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.108 0.3195
Schistosoma mansoni polycystin 1-related 0.002 0.0039 0.0047
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0525 0.2115
Mycobacterium ulcerans lipase LipD 0.015 0.1141 0.4598
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0503 0.2131
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0044 0.0062
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0629 0.0876
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0152 0.1154 0.1612
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0224 0.0927
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0069 0.0654
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.005
Giardia lamblia Heat shock protein HSP 90-alpha 0.0045 0.0251 0.1054
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0336 0.2711 0.3091
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.015 0.1141 0.1426
Onchocerca volvulus Serine\/threonine kinase homolog 0.0091 0.0644 0.0639
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0006 0.0007
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.053 0.4034
Trichomonas vaginalis D-aminoacylase, putative 0.015 0.1141 0.1137
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Schistosoma mansoni lipoxygenase 0.0082 0.0565 0.0785
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0344 0.0482
Mycobacterium tuberculosis Probable dehydrogenase 0.037 0.2996 0.3755
Mycobacterium ulcerans beta-lactamase 0.015 0.1141 0.4598
Loa Loa (eye worm) hypothetical protein 0.0026 0.0093 0.0106
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0363 0.0409
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0056 0.0348 0.2636
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.2343 0.2339
Plasmodium falciparum glutathione reductase 0.0162 0.1242 0.9514
Schistosoma mansoni hypothetical protein 0.0035 0.0168 0.0228
Brugia malayi mbt repeat family protein 0.0049 0.0287 0.0322
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0017 0.0016 0.0013
Onchocerca volvulus 0.002 0.0044 0.0039
Echinococcus multilocularis muscleblind protein 1 0.0151 0.1147 0.1603
Loa Loa (eye worm) glutaminase 0.0291 0.2328 0.2654
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0295 0.2364 1
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0525 0.052
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0005 0.0005
Schistosoma mansoni alpha-glucosidase 0.0289 0.2316 0.3241
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0017 0.0016 0.0014
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0017 0.0016 0.0045
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0224 0.0927
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.0722 0.307
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0344 0.0476
Brugia malayi jmjC domain containing protein 0.0016 0.0006 0.0001
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0148 0.0143
Trypanosoma cruzi heat shock protein, putative 0.003 0.0124 0.0507
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0056 0.0348 0.1395
Toxoplasma gondii Hsp90 domain-containing protein 0.017 0.1306 0.5292
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Leishmania major DNA polymerase kappa, putative 0.0018 0.0029 0.0097
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.015 0.1141 0.1593
Schistosoma mansoni terminal deoxycytidyl transferase 0.0059 0.0374 0.0518
Schistosoma mansoni endoplasmin 0.0045 0.0251 0.0346
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1054 0.8771 1
Loa Loa (eye worm) hypothetical protein 0.015 0.1141 0.1301
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0525 0.208
Mycobacterium tuberculosis Probable esterase LipL 0.015 0.1141 0.1426
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0042 0.0228 0.2622
Loa Loa (eye worm) hypothetical protein 0.0056 0.0344 0.0392
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0039 0.0054
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0474 0.3877 0.4421
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1052 0.4261
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0017 0.0016 0.0014
Schistosoma mansoni hypothetical protein 0.086 0.7135 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.2343 0.2339
Brugia malayi nuclear hormone receptor 0.002 0.0044 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0029 0.0101
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.0862 0.1208
Schistosoma mansoni aldehyde dehydrogenase 0.0307 0.2463 0.3447
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Loa Loa (eye worm) beta-lactamase 0.015 0.1141 0.1301
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.037 0.2996 0.3755
Trypanosoma brucei heat shock protein, putative 0.0045 0.0251 0.1044
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.015 0.1141 0.1593
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0044 0.0055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.2343 0.2339
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0017 0.0016 0.0047
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0044 0.0062
Leishmania major aldehyde dehydrogenase, putative 0.0017 0.0016 0.0045
Schistosoma mansoni microtubule-associated protein tau 0.0709 0.5856 0.8206
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0287 0.0402
Echinococcus granulosus phd:f box containing protein 0.0016 0.0006 0.0008
Mycobacterium tuberculosis Conserved protein 0.015 0.1141 0.1426
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0287 0.0327
Loa Loa (eye worm) hypothetical protein 0.0027 0.0097 0.0111
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0044 0.0045
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0044 0.0055
Echinococcus multilocularis thioredoxin glutathione reductase 0.0164 0.1255 0.1755
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0029 0.0097
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0097 0.0111
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0006 0.0001
Onchocerca volvulus 0.0051 0.0301 0.0296
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0044 0.005
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0006 0.0007
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.1185 0.1482
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.005
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0301 0.0415
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0044 0.0062
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0525 0.3997
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.1961 0.2748
Brugia malayi steroid hormone receptor 0.002 0.0044 0.0045
Echinococcus granulosus histone lysine methyltransferase setb 0.0152 0.1154 0.1618
Brugia malayi Hsp90 protein 0.003 0.0124 0.0136
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0736 0.1025
Trypanosoma cruzi trypanothione reductase, putative 0.0162 0.1242 0.5245
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0186 0.026
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0174 0.0244
Brugia malayi jmjC domain containing protein 0.0016 0.0006 0.0001
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.0722 0.0819
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0008 0.0009
Onchocerca volvulus 0.0027 0.0097 0.0093
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0307 0.2463 0.3443
Mycobacterium tuberculosis Probable lipase LipE 0.015 0.1141 0.1426
Loa Loa (eye worm) hypothetical protein 0.0151 0.1147 0.1307
Echinococcus multilocularis protein patched 0.0043 0.0238 0.0332
Mycobacterium ulcerans glutaminase 0.0291 0.2328 0.9447
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0525 0.0593
Brugia malayi heat shock protein 90 0.0045 0.0251 0.0281
Schistosoma mansoni hypothetical protein 0.005 0.0299 0.0413
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0029 0.0101
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0056 0.0348 0.1395
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0029 0.0101
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0224 0.0927
Echinococcus multilocularis microtubule associated protein 2 0.0709 0.5856 0.8186
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0017 0.0016 0.0014
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0186 0.0736
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.2343 0.2339
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0006 0.0004
Trypanosoma brucei chrX additional, unordered contigs 0.0018 0.0029 0.0101
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0056 0.0348 0.0481
Schistosoma mansoni coup transcription factor 0.002 0.0044 0.0055
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0069 0.026
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0039 0.026
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0299 0.0336
Schistosoma mansoni alpha glucosidase 0.0075 0.0503 0.0699
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0008 0.0011
Loa Loa (eye worm) aldehyde dehydrogenase 0.0017 0.0016 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0044 0.0045
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0525 0.2203
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0882 0.1006
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0097 0.0111
Schistosoma mansoni inositol monophosphatase 0.0113 0.0825 0.115
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0287 0.0401
Trypanosoma cruzi trypanothione reductase, putative 0.0056 0.0348 0.1453
Schistosoma mansoni aldehyde dehydrogenase 0.0017 0.0016 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0644 0.0639
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0017 0.0016 0.0022
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0039 0.0054
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0042 0.0228 0.0908
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0056 0.0348 0.1357
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0044 0.005
Loa Loa (eye worm) hypothetical protein 0.0034 0.0164 0.0187
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0503 0.2131
Leishmania major aldehyde dehydrogenase, putative 0.0017 0.0016 0.0045
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0017 0.0016 0.0022
Echinococcus granulosus FTZ F1 alpha 0.002 0.0044 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0219 0.0907
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0017 0.0016 0.0047
Schistosoma mansoni hypothetical protein 0.002 0.0039 0.0047
Schistosoma mansoni DNA polymerase eta 0.0059 0.0374 0.0518
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0044 0.0055
Giardia lamblia Alcohol dehydrogenase 0.0017 0.0016 0.0047
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0186 0.026
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0056 0.0348 0.043
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0238 0.0333
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.2343 0.2339
Plasmodium falciparum glutathione reductase 0.0056 0.0348 0.2636
Brugia malayi Glycosyl hydrolases family 31 protein 0.0075 0.0503 0.0568
Mycobacterium tuberculosis Probable reductase 0.037 0.2996 0.3755
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.005
Brugia malayi Pre-SET motif family protein 0.0152 0.1154 0.1311
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0044 0.0062
Echinococcus multilocularis endoplasmin 0.0042 0.0228 0.0319
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0113 0.0825 0.0821
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0029 0.0101
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0017 0.0016 0.0014
Brugia malayi Pre-SET motif family protein 0.1054 0.8771 1
Onchocerca volvulus 0.0194 0.1515 0.1511
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0113 0.0825 0.3477
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0016 0.0005 0.0007
Plasmodium vivax heat shock protein 86, putative 0.0045 0.0251 0.1894
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Echinococcus granulosus heat shock protein 0.0045 0.0251 0.0352
Schistosoma mansoni hypothetical protein 0.0042 0.0225 0.0308
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0056 0.0348 0.2636
Echinococcus multilocularis cpg binding protein 0.0032 0.0146 0.0204
Mycobacterium ulcerans heat shock protein 90 0.0042 0.0228 0.0867
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0056 0.0348 0.0486
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.03 0.1252
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0017 0.0016 0.0022
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0059 0.0374 0.037
Schistosoma mansoni hypothetical protein 0.0435 0.3546 0.4965
Echinococcus granulosus dna polymerase eta 0.0059 0.0374 0.0524
Echinococcus granulosus lamin 0.0027 0.0097 0.0137
Schistosoma mansoni glutaminase 0.0291 0.2328 0.3257
Loa Loa (eye worm) RNA binding protein 0.0325 0.2613 0.2979
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0293 0.2343 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.0363 0.1459
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0017 0.0016 0.0015
Leishmania major aldehyde dehydrogenase, putative 0.0017 0.0016 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0186 0.0181
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0093 0.0678
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0029 0.0101
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0385 0.0533
Loa Loa (eye worm) heat shock protein 75 0.003 0.0124 0.0142
Trypanosoma brucei heat shock protein, putative 0.0045 0.0251 0.1044
Leishmania major heat shock protein 83-1 0.0045 0.0251 0.1002
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0029 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0644 0.0639
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0005
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0174 0.0237
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0005 0.0007
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0146 0.1102 0.1544
Schistosoma mansoni tar DNA-binding protein 0.0325 0.2613 0.3658
Trichomonas vaginalis sucrase-isomaltase, putative 0.0075 0.0503 0.0498
Loa Loa (eye worm) hypothetical protein 0.0059 0.0374 0.0427
Brugia malayi jmjC domain containing protein 0.0059 0.037 0.0417
Plasmodium falciparum heat shock protein 90 0.0045 0.0251 0.1894
Brugia malayi RNA recognition motif domain containing protein 0.0325 0.2613 0.2975
Echinococcus granulosus heat shock protein 90 0.0038 0.0197 0.0276
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0044 0.0039
Plasmodium vivax SET domain protein, putative 0.0152 0.1154 0.8838
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0005
Echinococcus multilocularis dna polymerase eta 0.0059 0.0374 0.0523
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.0029 0.0097
Treponema pallidum NADH oxidase 0.0056 0.0348 0.1467
Trichomonas vaginalis maltase-glucoamylase, putative 0.0075 0.0503 0.0498
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0255 0.025
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.005
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0059 0.0374 0.0427
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0374 0.1565
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.2343 0.2339
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0238 0.0271
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0209 0.1634 0.2285
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0251 0.1044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0629 0.0876
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0348 0.1453
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0255 0.025
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.0029 0.0034
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0006 0.0008
Loa Loa (eye worm) inositol-1 0.0113 0.0825 0.0941
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0186 0.0181
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0069 0.0271
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0017 0.0016 0.0018
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.2364 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0219 0.0907
Brugia malayi CHE-14 protein 0.0043 0.0238 0.0266
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0113 0.0825 0.3337
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0152 0.1154 0.1614
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0044 0.0045
Trichomonas vaginalis penicillin-binding protein, putative 0.015 0.1141 0.1137
Brugia malayi jmjC domain containing protein 0.0016 0.0006 0.0001
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0044 0.0055
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0287 0.0282
Echinococcus multilocularis lamin 0.0027 0.0097 0.0136
Trichomonas vaginalis D-aminoacylase, putative 0.015 0.1141 0.1137
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0411 0.3345 1
Trypanosoma brucei unspecified product 0.0041 0.0219 0.0907
Echinococcus granulosus microtubule associated protein 2 0.0709 0.5856 0.8207
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0113 0.0825 0.3477
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.0374 0.0421
Schistosoma mansoni hypothetical protein 0.0017 0.0016 0.0015
Onchocerca volvulus 0.005 0.0299 0.0294
Toxoplasma gondii heat shock protein 90, putative 0.0045 0.0251 0.1002
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0017 0.0016 0.0022
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0069 0.0491
Loa Loa (eye worm) glutathione reductase 0.0162 0.1242 0.1416
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0007
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0348 0.1453
Schistosoma mansoni cpg binding protein 0.0032 0.0146 0.0198
Trypanosoma brucei hypothetical protein, conserved 0.015 0.1141 0.4815
Echinococcus multilocularis deoxyribonuclease 1 2 0.0016 0.0005 0.0007
Echinococcus granulosus neutral sphingomyelinase 0.0016 0.0005 0.0007
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.003 0.0124 0.0174
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0629 0.088
Giardia lamblia Fructose-bisphosphate aldolase 0.0293 0.2343 1
Echinococcus granulosus GPCR family 2 0.0016 0.0008 0.0011
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0056 0.0348 0.2636
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0186 0.026
Echinococcus granulosus tar DNA binding protein 0.0325 0.2613 0.3662
Echinococcus multilocularis lamin dm0 0.0027 0.0097 0.0136
Echinococcus multilocularis dnaJ subfamily B 0.0435 0.3546 0.4956
Echinococcus granulosus beta LACTamase domain containing family member 0.015 0.1141 0.1599
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0044 0.0045
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0044 0.0062
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0059 0.0374 0.0464
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0044 0.0062
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0503 0.0498
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0044 0.0062
Schistosoma mansoni lamin 0.0027 0.0097 0.013
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.1961 0.2741
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0056 0.0348 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0629 0.0717
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0108 0.0103
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0017 0.0016 0.0045
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0017 0.0016 0.0045
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0091 0.0644 0.0902
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0059 0.0374 0.0518
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0017 0.0016 0.0047
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0044 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0186 0.0181
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0374 0.1565
Schistosoma mansoni hypothetical protein 0.0042 0.0225 0.0308
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0568 0.079
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0044 0.0062
Leishmania major hypothetical protein, conserved 0.0016 0.0006 0.0004
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.053 0.4034
Trichomonas vaginalis heat shock protein, putative 0.0038 0.0197 0.0192

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 190 nM In vitro antagonistic activity of the compound towards LTB4 receptor was evaluated by inhibition of binding of [3H]-LTB4 to human neutrophils ChEMBL. No reference
IC50 (binding) = 190 nM In vitro antagonistic activity of the compound towards LTB4 receptor was evaluated by inhibition of binding of [3H]-LTB4 to human neutrophils ChEMBL. No reference
Ki (binding) = 751 nM Compound was evaluated for inhibition of binding of [3H]-LTB4 to LTB4 receptor in guinea-pig lung membranes ChEMBL. No reference
Ki (binding) = 751 nM Compound was evaluated for inhibition of binding of [3H]-LTB4 to LTB4 receptor in guinea-pig lung membranes ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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