Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0936 | 0.1186 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.7362 | 0.7362 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0127 | 0.0127 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.7362 | 0.7362 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0651 | 0.0796 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0021 | 0.268 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4688 | 0.4688 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.4688 | 0.6332 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.268 | 1 |
Schistosoma mansoni | neutral sphingomyelinase | 0.0004 | 0.0071 | 0.0071 |
Trichomonas vaginalis | Phospholipase C precursor, putative | 0.0004 | 0.0071 | 0.0199 |
Trichomonas vaginalis | skeletal muscle/kidney enriched inositol 5-phosphatase, putative | 0.0004 | 0.0071 | 0.0199 |
Onchocerca volvulus | 0.0031 | 0.4403 | 1 | |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.1213 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.268 | 0.3578 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0796 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.7362 | 1 |
Entamoeba histolytica | inositol polyphosphate-5-phosphatase, putative | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.7362 | 0.7362 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0021 | 0.268 | 1 |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0651 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Trichomonas vaginalis | type IV inositol 5-phosphatase, putative | 0.0004 | 0.0071 | 0.0199 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0071 | 0.0199 |
Toxoplasma gondii | exonuclease III APE | 0.0021 | 0.268 | 0.2966 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.268 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.268 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.268 | 1 |
Schistosoma mansoni | carbon catabolite repressor protein | 0.0004 | 0.0071 | 0.0071 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0956 | 0.1213 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0021 | 0.268 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4403 | 0.4403 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0021 | 0.268 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.268 | 0.3578 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.4688 | 0.6332 |
Schistosoma mansoni | cript-related | 0.0004 | 0.0071 | 0.0071 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.1213 |
Trichomonas vaginalis | ocrl type II inositol 5-phosphatase, putative | 0.0004 | 0.0071 | 0.0199 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.268 | 0.3578 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.268 | 1 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0021 | 0.268 | 1 |
Trichomonas vaginalis | type II inositol 5-phosphatase, putative | 0.0004 | 0.0071 | 0.0199 |
Plasmodium falciparum | DNase I-like protein, putative | 0.0004 | 0.0071 | 0.0265 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.7362 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.7362 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.7362 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.7362 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.7362 | 1 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase domain containing protein | 0.0004 | 0.0071 | 0.0265 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.268 | 0.3578 |
Schistosoma mansoni | nocturnin | 0.0004 | 0.0071 | 0.0071 |
Schistosoma mansoni | synaptojanin | 0.0004 | 0.0071 | 0.0071 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4688 | 0.4688 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0651 | 0.0796 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0542 | 0.1969 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase domain containing protein | 0.0004 | 0.0071 | 0.0265 |
Entamoeba histolytica | inositol polyphosphate 5-phosphatase, putative | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | synaptojanin | 0.0004 | 0.0071 | 0.0071 |
Schistosoma mansoni | hypothetical protein | 0.0004 | 0.0071 | 0.0071 |
Plasmodium falciparum | endonuclease/exonuclease/phosphatase family protein, putative | 0.0004 | 0.0071 | 0.0265 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.4403 | 0.5942 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0021 | 0.268 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.4403 | 0.5942 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.268 | 0.268 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0796 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.268 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.268 | 0.268 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | ocrl type II inositol 5-phosphatase | 0.0004 | 0.0071 | 0.0071 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.8869 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0021 | 0.268 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0021 | 0.268 | 1 |
Plasmodium falciparum | exodeoxyribonuclease III, putative | 0.0004 | 0.0071 | 0.0265 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0071 | 0.0199 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0071 | 0.0199 |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0004 | 0.0071 | 0.0265 |
Trichomonas vaginalis | sphingomyelinase C 2 precursor, putative | 0.0004 | 0.0071 | 0.0199 |
Entamoeba histolytica | sphingomyelinase C precursor, putative | 0.0004 | 0.0071 | 0.0265 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.