TDR Targets

Basic information

Technical information

TDR Targets ID: 876324
Name: ethyl 3-[(3-cyanophenyl)sulfonyl-(phenylmethy l)amino]propanoate
MW: 372.438 | Formula: C19H20N2O4S
H donors: 0 H acceptors: 4 LogP: 2.47 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: CCOC(=O)CCN(S(=O)(=O)c1cccc(c1)C#N)Cc1ccccc1
InChi: 1S/C19H20N2O4S/c1-2-25-19(22)11-12-21(15-16-7-4-3-5-8-16)26(23,24)18-10-6-9-17(13-18)14-20/h3-10,13H,2,11-12,15H2,1H3
InChiKey: XLJSFMILPXLPAM-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

3-[(3-cyanophenyl)sulfonyl-(phenylmethyl)amino]propanoic acid ethyl ester
3-[benzyl-(3-cyanophenyl)sulfonyl-amino]propionic acid ethyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0021	0.0053	0.0005
Brugia malayi	Niemann-Pick C1 protein precursor	0.0105	0.1033	0.2459
Plasmodium falciparum	isocitrate dehydrogenase [NADP], mitochondrial	0.005	0.0385	1
Loa Loa (eye worm)	MH2 domain-containing protein	0.0377	0.42	1
Echinococcus multilocularis	mothers against decapentaplegic 5	0.0026	0.0103	0.0054
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0032	0.0176	0.0211
Brugia malayi	hypothetical protein	0.0026	0.0108	0.0258
Echinococcus multilocularis	Niemann Pick C1 protein	0.0151	0.1561	0.1529
Schistosoma mansoni	TGF-beta signal transducer Smad2	0.0026	0.0103	0.0088
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0021	0.0053	0.0005
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0021	0.0053	0.0005
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.0362	0.0522
Entamoeba histolytica	hypothetical protein	0.0114	0.1128	1
Schistosoma mansoni	tar DNA-binding protein	0.0066	0.0578	0.0881
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0048	0.0362	0.0522
Echinococcus multilocularis	isocitrate dehydrogenase 2 (NADP+)	0.005	0.0385	0.0339
Echinococcus multilocularis	isocitrate dehydrogenase	0.005	0.0385	0.0339
Brugia malayi	hypothetical protein	0.0114	0.1128	0.2686
Schistosoma mansoni	retinoic acid receptor RXR	0.0021	0.0053	0.0005
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0407	0.086
Loa Loa (eye worm)	transcription factor SMAD2	0.0377	0.42	1
Brugia malayi	steroid hormone receptor	0.0021	0.0053	0.0126
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0114	0.1128	0.1091
Echinococcus multilocularis	geminin	0.0535	0.6044	0.6065
Trypanosoma cruzi	isocitrate dehydrogenase, putative	0.005	0.0385	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.0362	0.0522
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1333	0.3093
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0021	0.0053	0.0008
Entamoeba histolytica	hypothetical protein	0.0114	0.1128	1
Brugia malayi	MH2 domain containing protein	0.0026	0.0103	0.0244
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0032	0.0176	0.0211
Brugia malayi	isocitrate dehydrogenase	0.005	0.0385	0.0916
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0021	0.0053	0.0005
Brugia malayi	TAR-binding protein	0.0066	0.0578	0.1375
Schistosoma mansoni	tar DNA-binding protein	0.0066	0.0578	0.0881
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0021	0.0053	0.0126
Echinococcus granulosus	mothers against decapentaplegic 5	0.0026	0.0103	0.0088
Brugia malayi	Isocitrate dehydrogenase	0.005	0.0385	0.0916
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0048	0.0362	0.0316
Brugia malayi	Smad1	0.0026	0.0103	0.0244
Loa Loa (eye worm)	MH2 domain-containing protein	0.0026	0.0103	0.0127
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.005	0.0385	0.0339
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0048	0.0362	0.0753
Loa Loa (eye worm)	steroid hormone receptor	0.0021	0.0053	0.0008
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0021	0.0053	0.0003
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0032	0.0176	0.0211
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0021	0.0053	0.0126
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0048	0.0362	0.0316
Loa Loa (eye worm)	RNA binding protein	0.0066	0.0578	0.1272
Toxoplasma gondii	isocitrate dehydrogenase	0.005	0.0385	1
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0021	0.0053	0.0005
Schistosoma mansoni	hypothetical protein	0.0044	0.0312	0.0437
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0021	0.0053	0.0126
Echinococcus granulosus	potassium voltage gated channel protein	0.026	0.2834	0.4646
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0048	0.0362	0.0863
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0053	0.0008
Loa Loa (eye worm)	Smad1	0.0026	0.0103	0.0127
Loa Loa (eye worm)	hypothetical protein	0.0105	0.1033	0.2369
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0449	0.0963
Schistosoma mansoni	Smad4	0.0026	0.0103	0.0088
Schistosoma mansoni	thyroid hormone receptor	0.0021	0.0053	0.0005
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0053	0.0008
Schistosoma mansoni	smad1 5 8 and	0.0026	0.0103	0.0088
Trypanosoma brucei	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.005	0.0385	1
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.005	0.0385	0.0339
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0021	0.0053	0.0126
Echinococcus granulosus	potassium voltage gated channel subfamily A	0.026	0.2834	0.4646
Brugia malayi	Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog	0.0021	0.005	0.0118
Trichomonas vaginalis	set domain proteins, putative	0.0253	0.2762	1
Schistosoma mansoni	hypothetical protein	0.0535	0.6044	1
Echinococcus granulosus	tar DNA binding protein	0.0066	0.0578	0.0881
Leishmania major	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.005	0.0385	1
Echinococcus multilocularis	Niemann Pick C1 protein	0.0105	0.1033	0.0995
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0053	0.0008
Echinococcus granulosus	TGF beta signal transducer SmadC	0.0026	0.0103	0.0088
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0021	0.0053	0.0126
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0021	0.0053	0.0126
Schistosoma mansoni	tar DNA-binding protein	0.0066	0.0578	0.0881
Mycobacterium tuberculosis	Proteasome alpha subunit PrcA; assembles with beta subunit PrcB.	0.0873	1	1
Brugia malayi	Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit	0.0021	0.005	0.0118
Echinococcus granulosus	X box binding protein 1	0.0308	0.3402	0.5592
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0021	0.0053	0.0005
Loa Loa (eye worm)	MH1 domain-containing protein	0.0026	0.0103	0.0127
Schistosoma mansoni	smad1 5 8 and	0.0026	0.0103	0.0088
Onchocerca volvulus		0.0253	0.2762	1
Plasmodium vivax	SET domain protein, putative	0.0032	0.0176	0.2446
Echinococcus granulosus	NADP dependent isocitrate dehydrogenase	0.005	0.0385	0.0559
Schistosoma mansoni	patched 1	0.0045	0.0331	0.0469
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0021	0.0053	0.0005
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0051	0.0393	0.0935
Brugia malayi	MH2 domain containing protein	0.0377	0.42	1
Entamoeba histolytica	hypothetical protein	0.0114	0.1128	1
Schistosoma mansoni	tar DNA-binding protein	0.0066	0.0578	0.0881
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0052	0.0407	0.086
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0021	0.0053	0.0126
Echinococcus multilocularis	survival motor neuron protein 1	0.0248	0.2695	0.2677
Echinococcus granulosus	survival motor neuron protein 1	0.0248	0.2695	0.4413
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0021	0.0053	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0053	0.0008
Schistosoma mansoni	niemann-pick C1 (NPC1)	0.0107	0.1052	0.1672
Brugia malayi	latrophilin 2 splice variant baaae	0.0035	0.0216	0.0513
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0021	0.0053	0.0008
Echinococcus granulosus	Smad4	0.0026	0.0103	0.0088
Echinococcus granulosus	expressed conserved protein	0.0099	0.0958	0.1516
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0053	0.0008
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0021	0.0053	0.0005
Brugia malayi	photoreceptor-specific nuclear receptor	0.0021	0.0053	0.0126
Schistosoma mansoni	hypothetical protein	0.0044	0.0312	0.0437
Schistosoma mansoni	smad1 5 8 and	0.0026	0.0103	0.0088
Loa Loa (eye worm)	abnormal chemotaxis protein 14	0.0045	0.0331	0.0677
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0021	0.0053	0.0008
Loa Loa (eye worm)	TAR-binding protein	0.0066	0.0578	0.1272
Brugia malayi	RNA recognition motif domain containing protein	0.0066	0.0578	0.1375
Onchocerca volvulus		0.0051	0.0393	0.1255
Echinococcus multilocularis	smad	0.0026	0.0103	0.0054
Brugia malayi	MH1 domain containing protein	0.0026	0.0103	0.0244
Schistosoma mansoni	smad	0.0026	0.0103	0.0088
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0048	0.0362	0.0522
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0021	0.0053	0.0003
Brugia malayi	hypothetical protein	0.0248	0.2695	0.6416
Brugia malayi	Steroid receptor seven-up type 2	0.0021	0.0053	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0053	0.0008
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0052	0.0407	0.0968
Trypanosoma cruzi	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.005	0.0385	1
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1333	0.3093
Brugia malayi	ecdysteroid receptor	0.0021	0.0053	0.0126
Schistosoma mansoni	hypothetical protein	0.0044	0.0312	0.0437
Brugia malayi	MH1 domain containing protein	0.0026	0.0103	0.0244
Schistosoma mansoni	hypothetical protein	0.0044	0.0312	0.0437
Echinococcus multilocularis	sterol regulatory element binding protein	0.0045	0.0331	0.0284
Echinococcus granulosus	Niemann Pick C1 protein	0.0105	0.1033	0.164
Echinococcus granulosus	FTZ F1 alpha	0.0021	0.0053	0.0005
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0216	0.04
Brugia malayi	MH2 domain containing protein	0.0026	0.0103	0.0244
Schistosoma mansoni	voltage-gated potassium channel	0.026	0.2834	0.4646
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0114	0.1128	0.1799
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0021	0.0053	0.0005
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0032	0.0176	0.2446
Mycobacterium ulcerans	proteasome PrcA	0.0873	1	0.5
Schistosoma mansoni	hypothetical protein	0.0035	0.0216	0.0277
Schistosoma mansoni	coup transcription factor	0.0021	0.0053	0.0005
Brugia malayi	Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit	0.026	0.2834	0.6748
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0032	0.0176	0.0211
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0331	0.0677
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0021	0.0053	0.0003
Echinococcus granulosus	Niemann Pick C1 protein	0.0151	0.1561	0.2521
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0031	0.0162	0.0188
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0021	0.0053	0.0126
Schistosoma mansoni	hypothetical protein	0.0114	0.1128	0.1799
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0021	0.0053	0.0008
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0021	0.0053	0.0126
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.0362	0.0522
Echinococcus granulosus	sterol regulatory element binding protein	0.0045	0.0331	0.0469
Trypanosoma brucei	isocitrate dehydrogenase, putative	0.005	0.0385	1
Brugia malayi	hypothetical protein	0.0131	0.1333	0.3175
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0021	0.0053	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0108	0.0141
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0021	0.0053	0.0005
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0021	0.0053	0.0008
Echinococcus granulosus	Protein patched homolog 1	0.0045	0.0331	0.0469
Brugia malayi	nuclear receptor NHR-88	0.0021	0.0053	0.0126
Schistosoma mansoni	hypothetical protein	0.0051	0.0393	0.0572
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0021	0.0053	0.0005
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0223	0.2403	0.567
Echinococcus multilocularis	X box binding protein 1	0.0308	0.3402	0.3392
Loa Loa (eye worm)	hypothetical protein	0.0248	0.2695	0.6373
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0021	0.0053	0.0003
Echinococcus multilocularis	potassium voltage gated channel subfamily A	0.0248	0.2702	0.2684
Echinococcus granulosus	ecdysone induced protein 78C	0.0021	0.0053	0.0005
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0021	0.0053	0.0126
Plasmodium vivax	isocitrate dehydrogenase [NADP], mitochondrial, putative	0.005	0.0385	1
Schistosoma mansoni	survival motor neuron protein	0.0051	0.0393	0.0572
Echinococcus granulosus	geminin	0.0535	0.6044	1
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0021	0.0053	0.0005
Echinococcus multilocularis	Smad4	0.0026	0.0103	0.0054
Echinococcus multilocularis	expressed conserved protein	0.0099	0.0958	0.0919
Brugia malayi	Nuclear hormone receptor-like 1	0.0021	0.0053	0.0126
Brugia malayi	RNA binding protein	0.0066	0.0578	0.1375
Schistosoma mansoni	nuclear hormone receptor	0.0021	0.0053	0.0005
Echinococcus granulosus	smad	0.0026	0.0103	0.0088
Schistosoma mansoni	voltage-gated potassium channel	0.026	0.2834	0.4646
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0053	0.0008
Echinococcus multilocularis	ecdysone induced protein 78C	0.0021	0.0053	0.0003
Schistosoma mansoni	RAR-like nuclear receptor	0.0021	0.0053	0.0005
Echinococcus multilocularis	potassium voltage gated channel protein	0.026	0.2834	0.2818
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0021	0.0053	0.0003
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0021	0.0053	0.0003
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0021	0.0053	0.0008
Schistosoma mansoni	transcription factor LCR-F1	0.0114	0.1128	0.1799
Echinococcus multilocularis	FTZ F1 alpha	0.0021	0.0053	0.0003
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0021	0.0053	0.0005
Echinococcus multilocularis	protein dispatched 1	0.0052	0.0405	0.036
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0021	0.0053	0.0126
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0052	0.0407	0.0968
Echinococcus multilocularis	atpase aaa+ type core atpase aaa type core	0.0868	0.9933	1
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0032	0.0176	0.0128
Brugia malayi	nuclear hormone receptor	0.0021	0.0053	0.0126
Toxoplasma gondii	isocitrate dehydrogenase	0.005	0.0385	1
Echinococcus multilocularis	protein patched	0.0045	0.0331	0.0284
Echinococcus multilocularis	tar DNA binding protein	0.0066	0.0578	0.0534
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.005	0.0385	0.0339
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0021	0.0053	0.0126
Schistosoma mansoni	hypothetical protein	0.0535	0.6044	1
Loa Loa (eye worm)	hypothetical protein	0.026	0.2834	0.671
Onchocerca volvulus	Huntingtin homolog	0.0131	0.1333	0.4727
Schistosoma mansoni	hypothetical protein	0.0308	0.3402	0.5592
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0021	0.0053	0.0005
Schistosoma mansoni	thyroid hormone receptor	0.0021	0.0053	0.0005
Onchocerca volvulus	Huntingtin homolog	0.0131	0.1333	0.4727
Entamoeba histolytica	hypothetical protein	0.0114	0.1128	1
Echinococcus granulosus	histone lysine methyltransferase setb	0.0032	0.0176	0.0211
Brugia malayi	CHE-14 protein	0.0045	0.0331	0.0787
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0021	0.0053	0.0008
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0053	0.0008
Brugia malayi	Pre-SET motif family protein	0.0223	0.2403	0.5721
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0176	0.0304
Echinococcus multilocularis	TGF beta signal transducer SmadC	0.0026	0.0103	0.0054
Brugia malayi	Pre-SET motif family protein	0.0032	0.0176	0.0419
Onchocerca volvulus		0.0032	0.0176	0.0454
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0032	0.0176	0.0128
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0066	0.0578	0.1272
Schistosoma mansoni	NADP-specific isocitrate dehydrogenase	0.005	0.0385	0.0559
Schistosoma mansoni	tar DNA-binding protein	0.0066	0.0578	0.0881
Loa Loa (eye worm)	isocitrate dehydrogenase	0.005	0.0385	0.0808

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 876324