Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Onchocerca volvulus | 0.0033 | 1 | 0.5 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Onchocerca volvulus | 0.0033 | 1 | 0.5 | |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0033 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0033 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0033 | 1 | 0.5 |
Echinococcus multilocularis | aldehyde reductase | 0.0024 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 1 | 1 |
Onchocerca volvulus | 0.0033 | 1 | 0.5 | |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0033 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 1 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0033 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0033 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0033 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0033 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0033 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 1 | 0.5 |
Onchocerca volvulus | 0.0033 | 1 | 0.5 | |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0033 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0033 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 1 | 0.5 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Onchocerca volvulus | 0.0033 | 1 | 0.5 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0033 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0033 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0033 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0033 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Onchocerca volvulus | 0.0033 | 1 | 0.5 | |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0033 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 1 | 1 |
Echinococcus granulosus | aldehyde reductase | 0.0024 | 0.0153 | 0.0153 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Schistosoma mansoni | pol-related | 0.0033 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.