Detailed information for compound 877199

Basic information

Technical information
  • TDR Targets ID: 877199
  • Name: ethyl 4-(3-bromophenyl)-1,6-dimethyl-2-sulfan ylidene-3,4-dihydropyrimidine-5-carboxylate
  • MW: 369.277 | Formula: C15H17BrN2O2S
  • H donors: 1 H acceptors: 1 LogP: 2.85 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C1=C(C)N(C(=S)NC1c1cccc(c1)Br)C
  • InChi: 1S/C15H17BrN2O2S/c1-4-20-14(19)12-9(2)18(3)15(21)17-13(12)10-6-5-7-11(16)8-10/h5-8,13H,4H2,1-3H3,(H,17,21)
  • InChiKey: JWKCRUGKOZUCRF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ethyl 4-(3-bromophenyl)-1,6-dimethyl-2-thioxo-3,4-dihydropyrimidine-5-carboxylate
  • 4-(3-bromophenyl)-1,6-dimethyl-2-thioxo-3,4-dihydropyrimidine-5-carboxylic acid ethyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) hypothetical protein 0.0075 0.0043 0.0044
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0019 0.2393
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0055 0.526
Brugia malayi Immunoglobulin domain containing protein 0.0042 0.0008 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0051 0.4821
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0019 0.002
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0075 0.0043 0.0139
Onchocerca volvulus 0.192 0.2008 0.6626
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0019 0.002
Trypanosoma brucei cdc2-related kinase 1 0.0079 0.0046 0.3292
Echinococcus multilocularis rho associated protein kinase 0.0188 0.0163 0.0536
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0043 0.0042
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0087 0.0055 0.0179
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0077 0.0044 0.3165
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0127 0.0098 0.0322
Onchocerca volvulus 0.0053 0.0019 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus granulosus integrin linked protein kinase 0.0044 0.0009 0.0029
Schistosoma mansoni vesicular amine transporter 0.0146 0.0118 0.0116
Echinococcus granulosus serine:threonine protein kinase N2 0.0275 0.0256 0.0843
Echinococcus multilocularis cyclin dependent kinase 1 0.0079 0.0046 0.0151
Echinococcus granulosus 5'partial|protein kinase 0.0061 0.0028 0.009
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0084 0.0052 0.0169
Echinococcus multilocularis mitogen activated protein kinase 11 0.0167 0.014 0.0462
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0107 0.0076 0.025
Loa Loa (eye worm) TK protein kinase 0.0044 0.0009 0.0009
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0087 0.0055 0.0057
Schistosoma mansoni tyrosine kinase 0.0088 0.0057 0.0052
Brugia malayi Hr1 repeat family protein 0.0362 0.0348 0.0348
Brugia malayi Immunoglobulin I-set domain containing protein 0.2152 0.2256 0.2255
Giardia lamblia Kinase, CMGC GSK 0.0084 0.0052 0.4447
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0057 0.0023 0.1661
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0162 0.0135 0.0141
Trypanosoma brucei Flagellum attachment zone protein 20 0.0044 0.0009 0.0669
Onchocerca volvulus 0.0155 0.0128 0.0416
Echinococcus granulosus c-Jun N-terminal kinases 0.0279 0.0259 0.0854
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Brugia malayi kinase, mitochondrial precursor 0.0127 0.0098 0.0097
Echinococcus granulosus fibroblast growth factor receptor 4 0.0044 0.0009 0.0029
Loa Loa (eye worm) TK/ROR protein kinase 0.0077 0.0045 0.0046
Echinococcus multilocularis protein kinase c epsilon type 0.0102 0.0072 0.0235
Trypanosoma cruzi protein kinase, putative 0.0044 0.0009 0.0669
Loa Loa (eye worm) serine/threonine protein kinase 0.0044 0.0009 0.0009
Schistosoma mansoni roundabout 0.0075 0.0043 0.0037
Entamoeba histolytica cell division protein kinase 2, putative 0.0079 0.0046 0.4412
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0225 0.0202 0.0665
Entamoeba histolytica protein kinase domain containing protein 0.0084 0.0052 0.4945
Plasmodium falciparum glycogen synthase kinase 3 0.0084 0.0052 1
Echinococcus granulosus epidermal growth factor receptor 0.1441 0.1498 0.4943
Echinococcus granulosus cyclin dependent kinase 0.0079 0.0046 0.0151
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0087 0.0055 0.3925
Echinococcus granulosus rho-associated protein kinase 1 0.0188 0.0163 0.0536
Echinococcus granulosus tyrosine kinase 0.0044 0.0009 0.0029
Loa Loa (eye worm) hypothetical protein 0.0042 0.0008 0.0007
Plasmodium falciparum tyrosine kinase-like protein 0.0044 0.0009 0.1813
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0055 0.5226
Brugia malayi p70 ribosomal S6 kinase beta 0.0108 0.0078 0.0077
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0042 0.0008 0.0023
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0008 0.0007
Echinococcus granulosus tyrosine protein kinase Src64B 0.0088 0.0057 0.0185
Loa Loa (eye worm) hypothetical protein 0.0075 0.0043 0.0044
Brugia malayi P38 map kinase family protein 2 0.0167 0.014 0.014
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus multilocularis tyrosine protein kinase Srms 0.0084 0.0053 0.0171
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0087 0.0055 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0009 0.0896
Schistosoma mansoni ephrin receptor 0.0044 0.0009 0.0002
Entamoeba histolytica ankyrin repeat protein 0.0044 0.0009 0.0896
Echinococcus multilocularis tyrosine protein kinase pr2 0.0044 0.0009 0.0029
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0167 0.014 1
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1073 0.1106 0.3647
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0043 0.0042
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0044 0.0009 0.0002
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0087 0.0055 0.0057
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0044 0.001 0.0709
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0019 0.002
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0042 0.0008 0.0023
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0008 0.0007
Echinococcus granulosus tyrosine kinase 0.0084 0.0053 0.0171
Loa Loa (eye worm) hypothetical protein 0.0188 0.0163 0.017
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0044 0.0009 0.0009
Schistosoma mansoni protein kinase 0.0077 0.0044 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0025 0.0018
Echinococcus granulosus Immunoglobulin subtype 0.0042 0.0008 0.0023
Schistosoma mansoni serine/threonine kinase 0.0087 0.0055 0.005
Echinococcus multilocularis mitogen activated protein kinase 11 0.0167 0.014 0.0462
Trypanosoma cruzi cdc2-related kinase 3 0.0079 0.0046 0.3292
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0047 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0075 0.0043 0.0044
Entamoeba histolytica receptor protein kinase, putative 0.0044 0.0009 0.0896
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0087 0.0055 0.3925
Schistosoma mansoni neuroglian 0.0075 0.0043 0.0037
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Brugia malayi basement membrane proteoglycan 0.0042 0.0008 0.0007
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0088 0.0057 0.0185
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0044 0.0009 0.0029
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0044 0.0009 0.0029
Echinococcus granulosus lachesin 0.0075 0.0043 0.0139
Onchocerca volvulus 0.0044 0.0009 0.0025
Brugia malayi SRC-1 0.0088 0.0057 0.0056
Entamoeba histolytica ankyrin repeat protein 0.0044 0.0009 0.0896
Brugia malayi Protein kinase domain containing protein 0.1073 0.1106 0.1105
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0009 0.0009
Plasmodium vivax glycogen synthase kinase 3, putative 0.0084 0.0052 0.7576
Echinococcus multilocularis receptor type guanylyl cyclase 0.0044 0.0009 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0009 0.0009
Brugia malayi Protein kinase domain containing protein 0.8983 0.9534 0.9534
Loa Loa (eye worm) TK/FAK protein kinase 0.0044 0.0009 0.0009
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0044 0.0009 0.0896
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0052 0.0017 0.2239
Loa Loa (eye worm) hypothetical protein 0.0146 0.0118 0.0123
Brugia malayi Protein kinase domain containing protein 0.02 0.0175 0.0175
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0188 0.0163 0.0536
Entamoeba histolytica hypothetical protein 0.0044 0.0009 0.0896
Echinococcus granulosus Immunoglobulin 0.0042 0.0008 0.0023
Schistosoma mansoni tyrosine kinase 0.0088 0.0057 0.0052
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0055 0.5226
Echinococcus granulosus roundabout 2 0.0075 0.0043 0.0139
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0055 0.0021 0.0067
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0042 0.0008 0.0731
Schistosoma mansoni serine/threonine-protein kinase 0.0057 0.0023 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0105 0.0102
Onchocerca volvulus Tyrosine kinase homolog 0.1997 0.209 0.6896
Plasmodium vivax tyrosine kinase-like protein, putative 0.0044 0.0009 0.1373
Echinococcus granulosus titin 0.0066 0.0033 0.0106
Echinococcus granulosus serine:threonine protein kinase WNK1 0.0094 0.0063 0.0206
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Echinococcus granulosus low density lipoprotein receptor ldl 0.0042 0.0008 0.0023
Onchocerca volvulus 0.0044 0.0009 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0033 0.0027
Echinococcus multilocularis hemicentin 1 0.0075 0.0043 0.0139
Echinococcus granulosus cyclin dependent kinase 1 0.0079 0.0046 0.0151
Echinococcus multilocularis Immunoglobulin 0.0042 0.0008 0.0023
Onchocerca volvulus 0.0044 0.0009 0.0025
Entamoeba histolytica protein kinase 2, putative 0.0055 0.0021 0.2003
Schistosoma mansoni tyrosine kinase 0.1441 0.1498 0.1565
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.0006 0.0017
Brugia malayi bone morphogenetic protein type 1 receptor 0.0044 0.0009 0.0009
Echinococcus multilocularis rac serine:threonine kinase 0.0057 0.0023 0.0075
Trichomonas vaginalis AGC family protein kinase 0.0111 0.008 0.7675
Echinococcus multilocularis mitogen activated protein kinase 14 0.0167 0.014 0.0462
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0044 0.0009 0.0896
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0088 0.0057 0.0185
Loa Loa (eye worm) hypothetical protein 0.0221 0.0198 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0046 0.0041
Brugia malayi Protein kinase domain containing protein 0.0087 0.0055 0.0054
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Echinococcus granulosus RNA directed DNA polymerase 0.0042 0.0007 0.0023
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Loa Loa (eye worm) TK protein kinase 0.0044 0.0009 0.0009
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0279 0.0259 0.0854
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0075 0.0043 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0043 0.0042
Echinococcus multilocularis lachesin 0.0075 0.0043 0.0139
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0075 0.0043 0.0044
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Loa Loa (eye worm) RGC/RGC protein kinase 0.0044 0.0009 0.0009
Echinococcus granulosus serine/threonine protein kinase 0.0057 0.0023 0.0075
Brugia malayi Prion-like- 0.0075 0.0043 0.0042
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0044 0.0009 0.0009
Loa Loa (eye worm) TK/INSR protein kinase 0.1073 0.1106 0.1159
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0009 0.0896
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Loa Loa (eye worm) AGC/AKT protein kinase 0.0111 0.008 0.0084
Echinococcus granulosus protein kinase C gamma type 0.013 0.0101 0.0332
Trichomonas vaginalis CMGC family protein kinase 0.0079 0.0046 0.4412
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Echinococcus multilocularis tyrosine protein kinase csk 0.0044 0.0009 0.0029
Schistosoma mansoni protein kinase 0.0094 0.0063 0.0058
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0111 0.008 0.7675
Echinococcus multilocularis serine:threonine protein kinase N2 0.0087 0.0055 0.0179
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0279 0.0259 0.0272
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0052 0.4945
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus granulosus mitogen activated protein kinase 14 0.0167 0.014 0.0462
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0087 0.0055 0.0179
Echinococcus granulosus insulin receptor 0.1073 0.1106 0.3647
Brugia malayi basement membrane proteoglycan precursor 0.0042 0.0008 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0055 0.005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0042 0.0008 0.0007
Echinococcus multilocularis heat shock protein 70 0.0044 0.0009 0.0029
Trichomonas vaginalis STE family protein kinase 0.0094 0.0063 0.6017
Echinococcus granulosus tyrosine protein kinase Lyn 0.0121 0.0092 0.0301
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0077 0.0045 0.0145
Trichomonas vaginalis STE family protein kinase 0.0099 0.0068 0.6526
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0079 0.0046 0.0048
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0084 0.0052 0.369
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0057 0.0024 0.0017
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Schistosoma mansoni serine/threonine-protein kinase 0.0057 0.0023 0.0017
Entamoeba histolytica hypothetical protein 0.0044 0.0009 0.0896
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0009 0.0002
Loa Loa (eye worm) hypothetical protein 0.0221 0.0198 0.0207
Echinococcus granulosus NDR protein kinase 0.0087 0.0055 0.0179
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus granulosus tyrosine protein kinase csk 0.0044 0.0009 0.0029
Trypanosoma brucei polo-like protein kinase 0.0133 0.0105 0.7463
Brugia malayi protein kinase C3,putative 0.0047 0.0013 0.0013
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0076 0.0044 0.0045
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0088 0.0057 0.0185
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0088 0.0057 0.0185
Loa Loa (eye worm) hypothetical protein 0.0057 0.0023 0.0023
Loa Loa (eye worm) TK protein kinase 0.0044 0.0009 0.0009
Schistosoma mansoni protein kinase 0.0044 0.0009 0.0002
Echinococcus multilocularis c src tyrosine kinase 0.0057 0.0024 0.0076
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Echinococcus multilocularis insulin receptor 0.1073 0.1106 0.3647
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Brugia malayi Protein kinase domain containing protein 0.0916 0.0938 0.0938
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0019 0.002
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0133 0.0105 0.0109
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0055 0.0021 0.1495
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0019 0.002
Schistosoma mansoni nephrin 0.0075 0.0043 0.0037
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0075 0.0043 0.0139
Onchocerca volvulus Diphthamide biosynthesis protein 7 homolog 0.2879 0.303 1
Toxoplasma gondii protein kinase 0.0044 0.0009 0.1203
Schistosoma mansoni pyruvate dehydrogenase 0.0127 0.0098 0.0095
Brugia malayi protein unc-22 0.0066 0.0033 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni tyrosine kinase 0.1441 0.1498 0.1565
Brugia malayi hypothetical protein 0.0146 0.0118 0.0118
Brugia malayi Immunoglobulin domain containing protein 0.0042 0.0008 0.0007
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.0384 0.1266
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0068 0.6526
Entamoeba histolytica protein kinase, putative 0.0111 0.008 0.7675
Schistosoma mansoni pyruvate dehydrogenase 0.012 0.0091 0.0087
Echinococcus granulosus Protein kinase C brain isozyme 0.0145 0.0117 0.0383
Brugia malayi Protein kinase domain containing protein 0.0053 0.0019 0.0019
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Onchocerca volvulus 0.0044 0.0009 0.0025
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Schistosoma mansoni atypical protein kinase C 0.0101 0.007 0.0066
Echinococcus multilocularis serine:threonine protein kinase N2 0.0275 0.0256 0.0843
Schistosoma mansoni protein kinase 0.0077 0.0044 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0014 0.0006
Echinococcus multilocularis protein kinase 0.0044 0.0009 0.0029
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0047 0.0013 0.0013
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0088 0.0057 0.0185
Echinococcus multilocularis kinase suppressor of Ras 1 0.0044 0.0009 0.0029
Echinococcus granulosus dnaJ subfamily B 0.0396 0.0384 0.1266
Entamoeba histolytica protein kinase, putative 0.0108 0.0078 0.7452
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0087 0.0055 0.0179
Schistosoma mansoni cell adhesion molecule 0.0075 0.0043 0.0037
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0084 0.0053 0.0171
Loa Loa (eye worm) TK protein kinase 0.0044 0.0009 0.0009
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Loa Loa (eye worm) TK protein kinase 0.0075 0.0043 0.0044
Echinococcus granulosus tyrosine protein kinase Blk 0.0084 0.0053 0.0171
Loa Loa (eye worm) AGC/NDR protein kinase 0.0087 0.0055 0.0057
Echinococcus multilocularis epidermal growth factor receptor 0.2549 0.2678 0.8838
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Entamoeba histolytica PH domain containing protein kinase, putative 0.0057 0.0023 0.2226
Loa Loa (eye worm) hypothetical protein 0.0042 0.0008 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.8983 0.9534 1
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0084 0.0052 0.6635
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0087 0.0055 0.3925
Echinococcus multilocularis serine:threonine protein kinase 38 0.0087 0.0055 0.0179
Brugia malayi Tyrosine-protein kinase abl-1 0.0057 0.0024 0.0023
Schistosoma mansoni septate junction protein 0.0075 0.0043 0.0037
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0044 0.0009 0.0009
Brugia malayi oxidative-stress responsive 1 0.0138 0.011 0.0109
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Onchocerca volvulus 0.0053 0.0019 0.0058
Echinococcus granulosus protein kinase c epsilon type 0.0102 0.0072 0.0235
Schistosoma mansoni ephrin receptor 0.0044 0.0009 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0088 0.0057 0.0185
Echinococcus multilocularis tyrosine kinase 0.0044 0.0009 0.0029
Entamoeba histolytica tyrosin kinase, putative 0.0044 0.0009 0.0896
Plasmodium vivax tyrosine kinase-like protein, putative 0.0044 0.0009 0.1373
Entamoeba histolytica tyrosin kinase, putative 0.0052 0.0017 0.1669
Echinococcus granulosus netrin receptor unc 5 0.0042 0.0008 0.0023
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0042 0.0008 0.0023
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0105 1
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0075 0.0043 0.0135
Trichomonas vaginalis protein tyrosine kinase, putative 0.0044 0.0009 0.0896
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0044 0.0009 0.0029
Loa Loa (eye worm) TK/ACK protein kinase 0.0044 0.0009 0.0009
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0044 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Brugia malayi C-terminal src kinase protein 1 0.0044 0.0009 0.0009
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0077 0.0045 0.0145
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Brugia malayi hypothetical protein 0.0053 0.0019 0.0019
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0053 0.0019 0.0062
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Onchocerca volvulus 0.0044 0.0009 0.0025
Brugia malayi Immunoglobulin I-set domain containing protein 0.0066 0.0033 0.0032
Echinococcus granulosus defective proboscis extension response 0.0146 0.0118 0.0388
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0044 0.0009 0.0002
Schistosoma mansoni cell adhesion molecule 0.0075 0.0043 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0043 0.0042
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0042 0.0008 0.0023
Echinococcus granulosus tyrosine protein kinase ABL1 0.0053 0.0019 0.0062
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0009 0.0009
Echinococcus multilocularis protein KINase family member (kin 25) 0.0044 0.0009 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0009 0.0896
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0044 0.0009 0.1203
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0066 0.0033 0.0034
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0053 0.0019 0.0062
Trypanosoma brucei protein kinase, putative 0.0084 0.0052 0.369
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0044 0.0009 0.0029
Echinococcus multilocularis 0.0777 0.0791 0.2608
Entamoeba histolytica hypothetical protein 0.0044 0.0009 0.0896
Echinococcus granulosus tyrosine protein kinase Srms 0.0053 0.0019 0.0062
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0108 0.0078 0.0081
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Entamoeba histolytica protein kinase, putative 0.0075 0.0043 0.4062
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0084 0.0052 0.0054
Echinococcus multilocularis tyrosine kinase 0.0053 0.0019 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0052 0.4945
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0044 0.001 0.1274
Echinococcus multilocularis tyrosine protein kinase Abl 0.0057 0.0024 0.0076
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus multilocularis serine:threonine protein kinase WNK1 0.0094 0.0063 0.0206
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Echinococcus multilocularis mitogen activated protein kinase 3 0.0087 0.0055 0.018
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0044 0.0009 0.0025
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0053 0.0019 0.185
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0042 0.0008 0.0023
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0008 0.0007
Brugia malayi MAP kinase sur-1 0.0087 0.0055 0.0055
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0044 0.0009 0.0002
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0044 0.0009 0.0009
Loa Loa (eye worm) TK/RYK protein kinase 0.0044 0.0009 0.0009
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Echinococcus granulosus natriuretic peptide receptor 1 0.0044 0.0009 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Entamoeba histolytica serine/threonine kinase, putative 0.0044 0.0009 0.0896
Echinococcus granulosus tyrosine protein kinase pr2 0.0044 0.0009 0.0029
Schistosoma mansoni tyrosine kinase 0.1397 0.1451 0.1516
Loa Loa (eye worm) TK protein kinase 0.0044 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0044 0.0009 0.0896
Leishmania major developmentally regulated phosphoprotein-like protein 0.0127 0.0098 0.698
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0042 0.0008 0.0007
Trypanosoma brucei protein kinase, putative 0.0077 0.0044 0.3165
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0079 0.0046 0.3292
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Brugia malayi serine/threonine-protein kinase plk-2 0.0133 0.0105 0.0104
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus granulosus hemicentin 1 0.0075 0.0043 0.0139
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0044 0.0009 0.0896
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0008 0.0007
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0055 0.0021 0.405
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Trypanosoma brucei Pseudokinase, putative 0.0044 0.0009 0.0669
Loa Loa (eye worm) TK/KIN16 protein kinase 0.2152 0.2256 0.2365
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0043 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0055 0.0021 0.3069
Brugia malayi Steroid receptor seven-up type 2 0.0107 0.0076 0.0076
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0051 0.4821
Echinococcus granulosus mitogen activated protein kinase 11 0.0167 0.014 0.0462
Echinococcus granulosus neuroglian 0.0179 0.0153 0.0504
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0042 0.0008 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0044 0.0009 0.0002
Brugia malayi Peroxidasin 0.0075 0.0043 0.0042
Loa Loa (eye worm) TK/CSK protein kinase 0.0044 0.0009 0.0009
Brugia malayi Protein kinase domain containing protein 0.0516 0.0512 0.0512
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Trichomonas vaginalis AGC family protein kinase 0.0111 0.008 0.7675
Brugia malayi Protein kinase domain containing protein 0.0079 0.0046 0.0046
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0055 0.5226
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0044 0.001 0.0709
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0075 0.0043 0.0044
Onchocerca volvulus 0.0044 0.0009 0.0025
Loa Loa (eye worm) TK protein kinase 0.0044 0.0009 0.0009
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0077 0.0044 0.5691
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0044 0.0009 0.0025
Echinococcus granulosus retinal guanylyl cyclase 2 0.0044 0.0009 0.0029
Echinococcus granulosus tyrosine protein kinase shark 0.0053 0.0019 0.0062
Brugia malayi ephrin receptor 1 precursor 0.0044 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0013 0.0006
Echinococcus multilocularis peroxidasin 0.0075 0.0043 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni cell adhesion molecule 0.0188 0.0163 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0013 0.0006
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0044 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Plasmodium falciparum protein kinase, putative 0.0077 0.0044 0.8577
Schistosoma mansoni tyrosine kinase 0.1073 0.1106 0.1152
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0077 0.0044 0.3165
Giardia lamblia Kinase, CMGC CDK 0.0079 0.0046 0.3862
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Schistosoma mansoni cell adhesion molecule 0.0075 0.0043 0.0037
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Onchocerca volvulus Serine\/threonine kinase homolog 0.0133 0.0105 0.034
Brugia malayi Tyrosine-protein kinase PR2 0.0044 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0044 0.0009 0.0896
Loa Loa (eye worm) hypothetical protein 0.0042 0.0008 0.0007
Giardia lamblia Kinase, AGC PKA 0.0055 0.0021 0.1215
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Entamoeba histolytica serine/threonine kinase, putative 0.0044 0.0009 0.0896
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0055 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0019 0.002
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0102 0.0072 0.0075
Echinococcus multilocularis integrin linked protein kinase 0.0044 0.0009 0.0029
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Echinococcus granulosus retinal guanylyl cyclase 2 0.0044 0.0009 0.0029
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0007
Loa Loa (eye worm) protein kinase domain-containing protein 0.0044 0.0009 0.0009
Echinococcus granulosus tyrosine protein kinase Src42A 0.0088 0.0057 0.0185
Brugia malayi Protein kinase domain containing protein 0.0295 0.0277 0.0277
Brugia malayi C1-like domain containing protein 0.0047 0.0013 0.0013
Toxoplasma gondii protein kinase domain-containing protein 0.0044 0.0009 0.1203
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0107 0.0076 0.025
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0084 0.0052 0.0054
Schistosoma mansoni tyrosine protein kinase 0.0044 0.0009 0.0002
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0055 0.0021 0.0067
Loa Loa (eye worm) hypothetical protein 0.0075 0.0043 0.0044
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0008 0.0007
Brugia malayi Immunoglobulin domain containing protein 0.0042 0.0008 0.0007
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0044 0.0009 0.0029
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Echinococcus multilocularis Cyclin dependent kinase 2 associated protein 0.2879 0.303 1
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) thyroid receptor interactor 0.0156 0.0129 0.0135
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0046 0.0041
Echinococcus multilocularis ephrin type A receptor 4 A 0.0044 0.0009 0.0029
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Echinococcus granulosus STE20:SPS1 proline alanine rich protein 0.0138 0.011 0.0361
Brugia malayi SH2 domain containing protein 0.0053 0.0019 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0055 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0009 0.0009
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0044 0.0009 0.0669
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0167 0.014 1
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0087 0.0055 0.0057
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 2 0.0066 0.0033 0.2374
Entamoeba histolytica hypothetical protein 0.0044 0.0009 0.0896
Echinococcus multilocularis Immunoglobulin subtype 0.0042 0.0008 0.0023
Echinococcus multilocularis FL cytokine receptor 0.0044 0.0009 0.0029
Echinococcus granulosus raf serine:threonine protein kinase 0.0058 0.0025 0.008
Brugia malayi hypothetical protein 0.0044 0.0009 0.0009
Echinococcus granulosus protein kinase 0.0044 0.0009 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0117 0.0114
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0042 0.0008 0.0023
Echinococcus granulosus protein kinase shaggy 0.0084 0.0052 0.0169
Echinococcus granulosus titin 0.0066 0.0033 0.0106
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0044 0.0009 0.1203
Brugia malayi Fibronectin type III domain containing protein 0.0146 0.0118 0.0118
Schistosoma mansoni hypothetical protein 0.0396 0.0384 0.0395
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.8983 0.9534 1
Echinococcus multilocularis tyrosine protein kinase 0.0044 0.0009 0.0029
Echinococcus multilocularis hemicentin 1 0.0075 0.0043 0.0139
Echinococcus granulosus activated cdc42 kinase 1 0.0044 0.0009 0.0029
Brugia malayi Protein kinase domain containing protein 0.0196 0.0172 0.0171
Schistosoma mansoni tyrosine kinase 0.0057 0.0024 0.0017
Echinococcus multilocularis cyclin dependent kinase 5 0.0079 0.0046 0.0151
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0044 0.0009 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0075 0.0043 0.0037
Brugia malayi Protein kinase domain containing protein 0.0087 0.0055 0.0054
Entamoeba histolytica cell division protein kinase 2, putative 0.0079 0.0046 0.4412
Schistosoma mansoni septate junction protein 0.0075 0.0043 0.0037
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0044 0.0009 0.0896
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0075 0.0043 0.0139
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0087 0.0055 0.3925
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0163 0.0163
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0075 0.0043 0.0139
Echinococcus multilocularis RNA directed DNA polymerase 0.0042 0.0007 0.0023
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0044 0.0009 0.0029
Loa Loa (eye worm) hypothetical protein 0.0221 0.0198 0.0207
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0079 0.0046 0.0151
Giardia lamblia Kinase, CMGC MAPK 0.0087 0.0055 0.4793
Loa Loa (eye worm) TK/EGFR protein kinase 0.2549 0.2678 0.2809
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0019 0.002
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Trichomonas vaginalis CMGC family protein kinase 0.0079 0.0046 0.4412
Echinococcus multilocularis natriuretic peptide receptor 1 0.0044 0.0009 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0033 0.0027
Loa Loa (eye worm) hypothetical protein 0.0147 0.012 0.0125
Schistosoma mansoni nephrin 0.0179 0.0153 0.0153
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Onchocerca volvulus 0.0084 0.0052 0.0165
Brugia malayi Immunoglobulin I-set domain containing protein 0.0146 0.0118 0.0118
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0146 0.0118 0.0388
Entamoeba histolytica tyrosin kinase, putative 0.0044 0.0009 0.0896
Echinococcus granulosus tyrosine protein kinase HCK 0.0075 0.0043 0.0138
Echinococcus granulosus Immunoglobulin 0.0042 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) hypothetical protein 0.0075 0.0043 0.0044
Loa Loa (eye worm) hypothetical protein 0.2879 0.303 0.3178
Trypanosoma cruzi polo-like protein kinase, putative 0.0133 0.0105 0.7463
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0047 0.0013 0.0041
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0087 0.0055 0.3925
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Echinococcus multilocularis Immunoglobulin 0.0146 0.0118 0.0388
Giardia lamblia Kinase, CMGC CDK 0.0079 0.0046 0.3862
Schistosoma mansoni protein kinase 0.0044 0.0009 0.0002
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Echinococcus multilocularis twitchin 0.0066 0.0033 0.0106
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) STE/STE20/FRAY protein kinase 0.0138 0.011 0.0115
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0044 0.0009 0.0009
Brugia malayi Fes/CIP4 homology domain containing protein 0.0156 0.0129 0.0129
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0088 0.0057 0.0185
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0044 0.0009 0.0029
Entamoeba histolytica protein kinase, putative 0.0042 0.0008 0.0731
Schistosoma mansoni deleted in oral cancer 1/cdk2-associated protein-like 0.2879 0.303 0.3173
Schistosoma mansoni protein kinase 0.0044 0.0009 0.0002
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0088 0.0057 0.0185
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0105 1
Echinococcus granulosus kinase suppressor of Ras 1 0.0044 0.0009 0.0029
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0079 0.0046 0.0048
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0044 0.0009 0.0029
Echinococcus granulosus neuroglian 0.0075 0.0043 0.0139
Entamoeba histolytica protein kinase, putative 0.0084 0.0052 0.4945
Trichomonas vaginalis AGC family protein kinase 0.0111 0.008 0.7675
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0084 0.0052 0.0046
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0516 0.0512 0.0537
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0087 0.0055 0.0179
Trypanosoma cruzi cdc2-related kinase 1 0.0079 0.0046 0.3292
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Echinococcus multilocularis roundabout 2 0.0221 0.0198 0.0653
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0044 0.0009 0.0029
Echinococcus granulosus protein kinase c iota type 0.0101 0.007 0.023
Echinococcus multilocularis activin receptor type 0.0077 0.0044 0.0145
Echinococcus multilocularis epidermal growth factor receptor 0.1441 0.1498 0.4943
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Loa Loa (eye worm) TK/EPH protein kinase 0.0044 0.0009 0.0009
Schistosoma mansoni protein tyrosine kinase 0.0044 0.0009 0.0002
Schistosoma mansoni tyrosine kinase 0.0119 0.009 0.0086
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0044 0.0009 0.0009
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Brugia malayi Protein kinase c protein 2 0.0091 0.0059 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0009 0.0896
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0146 0.0118 0.0116
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0047 0.0013 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0009 0.0896
Echinococcus multilocularis protein kinase c iota type 0.0101 0.007 0.023
Schistosoma mansoni tyrosine kinase 0.0057 0.0024 0.0017
Schistosoma mansoni pyruvate dehydrogenase 0.012 0.0091 0.0087
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Echinococcus granulosus activin receptor type 0.0077 0.0044 0.0145
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Brugia malayi Guanylyl cyclase protein 23 0.0044 0.0009 0.0009
Echinococcus granulosus Cyclin dependent kinase 2 associated protein 0.2879 0.303 1
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Trichomonas vaginalis AGC family protein kinase 0.0111 0.008 0.7675
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0009 0.0896
Echinococcus granulosus tyrosine protein kinase otk 0.0075 0.0043 0.0139
Onchocerca volvulus 0.0066 0.0033 0.0103
Onchocerca volvulus 0.0044 0.0009 0.0025
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Echinococcus granulosus serine:threonine protein kinase N2 0.0362 0.0348 0.1148
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0044 0.0009 0.0029
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Loa Loa (eye worm) hypothetical protein 0.0147 0.012 0.0125
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0072 0.0067
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus multilocularis mitogen activated protein kinase 14 0.0167 0.014 0.0462
Entamoeba histolytica protein kinase domain containing protein 0.0077 0.0044 0.4241
Toxoplasma gondii STE kinase 0.0044 0.0009 0.1203
Entamoeba histolytica hypothetical protein 0.0044 0.0009 0.0896
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0009 0.0009
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Echinococcus multilocularis tyrosine protein kinase shark 0.0053 0.0019 0.0062
Brugia malayi Heparan sulfate 0.0042 0.0008 0.0007
Entamoeba histolytica serine/threonine kinase, putative 0.0044 0.0009 0.0896
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0043 0.0042
Loa Loa (eye worm) TK/ABL protein kinase 0.0053 0.0019 0.002
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Echinococcus multilocularis neuroglian 0.0075 0.0043 0.0139
Echinococcus granulosus roundabout 2 0.0075 0.0043 0.0139
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0087 0.0055 0.3925
Onchocerca volvulus 0.0053 0.0019 0.0058
Entamoeba histolytica protein kinase, putative 0.0087 0.0055 0.5226
Echinococcus granulosus tyrosine protein kinase Fyn 0.0088 0.0057 0.0185
Schistosoma mansoni serine/threonine protein kinase 0.0362 0.0348 0.0358
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0079 0.0046 0.3292
Onchocerca volvulus 0.0053 0.0019 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus granulosus contactin 0.0075 0.0043 0.0139
Giardia lamblia Kinase, Wnk 0.0094 0.0063 0.5625
Trichomonas vaginalis CMGC family protein kinase 0.0079 0.0046 0.4412
Loa Loa (eye worm) SRC-1 0.0088 0.0057 0.0059
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0087 0.0055 0.3925
Giardia lamblia Kinase, CMGC GSK 0.0084 0.0052 0.4447
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0084 0.0052 0.0169
Schistosoma mansoni protein kinase 0.0044 0.0009 0.0002
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0044 0.0009 0.0896
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 2 0.0099 0.0068 0.487
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Plasmodium vivax protein kinase, putative 0.0044 0.0009 0.1373
Loa Loa (eye worm) LAD-2 short isoform 0.0042 0.0008 0.0007
Onchocerca volvulus 0.0044 0.0009 0.0025
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0146 0.0118 0.0116
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Brugia malayi Stress-activated protein kinase jnk-1 0.0279 0.0259 0.0259
Entamoeba histolytica hypothetical protein 0.0044 0.0009 0.0896
Schistosoma mansoni protein kinase C mu 0.0047 0.0013 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni protein kinase 0.0044 0.0009 0.0002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0055 0.526
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0105 1
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Echinococcus multilocularis raf serine:threonine protein kinase 0.0058 0.0025 0.008
Brugia malayi protein-tyrosine kinase 0.0084 0.0053 0.0052
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0127 0.0098 0.698
Echinococcus multilocularis protein kinase 0.0044 0.0009 0.0029
Plasmodium falciparum protein kinase 5 0.0079 0.0046 0.8923
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0019 0.002
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Brugia malayi Raf kinase 0.0044 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) hypothetical protein 0.0075 0.0043 0.0044
Schistosoma mansoni serine/threonine RGC 0.0044 0.0009 0.0002
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0084 0.0053 0.0171
Brugia malayi hypothetical protein 0.0044 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Trypanosoma brucei rac serine-threonine kinase, putative 0.0111 0.008 0.5727
Schistosoma mansoni protein kinase 0.0138 0.011 0.0107
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0634 0.0638 0.2103
Trypanosoma cruzi Protein kinase B 0.0057 0.0023 0.1661
Entamoeba histolytica tyrosin kinase, putative 0.0044 0.0009 0.0896
Loa Loa (eye worm) hypothetical protein 0.0153 0.0125 0.0131
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0044 0.0009 0.0029
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0075 0.0043 0.0044
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0044 0.001 0.0709
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0167 0.014 0.0147
Entamoeba histolytica hypothetical protein 0.0044 0.0009 0.0896
Leishmania major protein kinase, putative 0.0044 0.0009 0.0669
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0025 0.0019
Entamoeba histolytica protein kinase domain containing protein 0.0084 0.0052 0.4945
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0044 0.0009 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Trypanosoma cruzi protein kinase, putative 0.0044 0.0009 0.0669
Onchocerca volvulus 0.0053 0.0019 0.0058
Echinococcus granulosus receptor type guanylyl cyclase 0.0044 0.0009 0.0029
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0042 0.0007 0.0023
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0105 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Schistosoma mansoni protein kinase 0.0044 0.0009 0.0002
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0044 0.0009 0.0009
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0145 0.0117 0.0383
Loa Loa (eye worm) hypothetical protein 0.0061 0.0028 0.0029
Echinococcus granulosus serine threonine protein kinase nrc 0.0055 0.0021 0.0067
Echinococcus multilocularis cyclin dependent kinase 1 0.0079 0.0046 0.0151
Onchocerca volvulus 0.0044 0.0009 0.0025
Echinococcus granulosus mitogen activated protein kinase 0.0087 0.0055 0.018
Echinococcus multilocularis transfer RNA-Thr 0.0044 0.0009 0.0029
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Entamoeba histolytica serine/threonine kinase, putative 0.0044 0.0009 0.0896
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Echinococcus multilocularis cyclin dependent kinase 0.0079 0.0046 0.0151
Echinococcus multilocularis titin 0.0066 0.0033 0.0106
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Entamoeba histolytica cysteine surface protein, putative 0.0044 0.0009 0.0896
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0167 0.014 1
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0009 0.0009
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0133 0.0105 0.0344
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Echinococcus granulosus twitchin 0.0212 0.0188 0.062
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0077 0.0044 0.0145
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.0006 0.0017
Brugia malayi Protein kinase domain containing protein 0.0111 0.008 0.008
Plasmodium vivax protein kinase Crk2 0.0079 0.0046 0.676
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0057 0.5449
Toxoplasma gondii AGC kinase 0.0108 0.0078 1
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0055 0.526
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Schistosoma mansoni tyrosine kinase 0.2549 0.2678 0.2803
Echinococcus multilocularis roundabout 2 0.0075 0.0043 0.0139
Loa Loa (eye worm) nuclear hormone receptor 0.0101 0.007 0.0073
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0044 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0047 0.0013 0.0013
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0075 0.0043 0.0139
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0044 0.0009 0.0009
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0077 0.0044 0.3165
Plasmodium falciparum protein kinase, putative 0.0044 0.0009 0.1813
Echinococcus multilocularis tyrosine protein kinase Blk 0.0084 0.0053 0.0171
Brugia malayi intracellular kinase 0.0084 0.0052 0.0051
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0044 0.0009 0.0002
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0044 0.0009 0.0002
Echinococcus multilocularis serine:threonine protein kinase N2 0.0362 0.0348 0.1148
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Schistosoma mansoni tyrosine kinase 0.0053 0.0019 0.0012
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Entamoeba histolytica receptor protein kinase, putative 0.0044 0.0009 0.0896
Entamoeba histolytica serine/threonine kinase, putative 0.0044 0.0009 0.0896
Echinococcus multilocularis netrin receptor unc 5 0.0042 0.0008 0.0023
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Loa Loa (eye worm) hypothetical protein 0.0146 0.0118 0.0123
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0105 1
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Echinococcus multilocularis Immunoglobulin 0.0042 0.0008 0.0023
Echinococcus multilocularis protein kinase 0.0061 0.0028 0.009
Echinococcus multilocularis tyrosine protein kinase otk 0.0075 0.0043 0.0139
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0057 0.0024 0.0076
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0105 1
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0009 0.0009
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0259 0.0264
Trichomonas vaginalis protein kinase atn1, putative 0.0044 0.0009 0.0896
Echinococcus multilocularis tyrosine protein kinase csk 0.0044 0.0009 0.0029
Plasmodium falciparum protein kinase, putative 0.0044 0.0009 0.1813
Brugia malayi Protein kinase domain containing protein 0.0053 0.0019 0.0019
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0042 0.0008 0.0023
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0044 0.0009 0.0029
Schistosoma mansoni protein kinase 0.0044 0.0009 0.0002
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Loa Loa (eye worm) RGC/RGC protein kinase 0.0044 0.0009 0.0009
Echinococcus granulosus activated cdc42 kinase 1 0.0044 0.0009 0.0029
Brugia malayi Protein kinase domain containing protein 0.0047 0.0013 0.0013
Echinococcus multilocularis tyrosine protein kinase csk 0.0044 0.0009 0.0029
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0044 0.0009 0.0029
Entamoeba histolytica protein kinase, putative 0.0111 0.008 0.7675
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1073 0.1106 0.3647
Brugia malayi Furin-like cysteine rich region family protein 0.2549 0.2678 0.2678
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0108 0.0078 0.0081
Echinococcus multilocularis tyrosine protein kinase csk 0.0044 0.0009 0.0029
Echinococcus granulosus mitogen activated protein kinase 3 0.0087 0.0055 0.018
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus granulosus basement membrane specific heparan sulfate 0.0042 0.0008 0.0023
Giardia lamblia Kinase, PLK 0.0133 0.0105 1
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0105 1
Brugia malayi Protein kinase domain containing protein 0.0053 0.0019 0.0019
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Brugia malayi hypothetical protein 0.0042 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0127 0.0098 0.0102
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0225 0.0202 0.0211
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0127 0.0098 0.0322
Trichomonas vaginalis STE family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) TK protein kinase 0.0084 0.0053 0.0054
Brugia malayi cell division control protein 2 homolog 0.0079 0.0046 0.0046
Schistosoma mansoni tyrosine kinase 0.1397 0.1451 0.1516
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0053 0.0019 0.0062
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0044 0.0009 0.0029
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Brugia malayi SH2 domain containing protein 0.0053 0.0019 0.0019
Echinococcus granulosus tyrosine protein kinase csk 0.0044 0.0009 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) RGC/RGC protein kinase 0.0044 0.0009 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0043 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0009 0.0002
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0019 0.002
Echinococcus granulosus tyrosine protein kinase 0.0044 0.0009 0.0029
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0044 0.0009 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.0077 0.0045 0.0044
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0008 0.0007
Echinococcus multilocularis protein kinase shaggy 0.0084 0.0052 0.0169
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0087 0.0055 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0111 0.008 0.7675
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0044 0.0009 0.0896
Entamoeba histolytica PH domain containing protein kinase, putative 0.0057 0.0023 0.2226
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0084 0.0052 0.369
Trypanosoma brucei protein kinase, putative 0.0087 0.0055 0.3925
Echinococcus multilocularis STE20:SPS1 proline alanine rich protein 0.0138 0.011 0.0361
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0043 0.0042
Loa Loa (eye worm) RGC/RGC protein kinase 0.0044 0.0009 0.0009
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Brugia malayi integrin-linked kinase 0.0044 0.0009 0.0009
Entamoeba histolytica serine/threonine protein kinase, putative 0.0133 0.0105 1
Brugia malayi Receptor family ligand binding region containing protein 0.0044 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus granulosus ephrin type A receptor 4 A 0.0044 0.0009 0.0029
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0225 0.0202 0.0665
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0075 0.0043 0.0037
Trypanosoma cruzi polo-like protein kinase, putative 0.0133 0.0105 0.7463
Brugia malayi map kinase activated protein kinase protein 2 0.0225 0.0202 0.0201
Loa Loa (eye worm) TK protein kinase 0.0077 0.0045 0.0046
Schistosoma mansoni hypothetical protein 0.0044 0.0009 0.0002
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0088 0.0057 0.0185
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0111 0.008 0.7675
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Loa Loa (eye worm) hypothetical protein 0.0102 0.0071 0.0074
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0057 0.0024 0.0076
Schistosoma mansoni titin 0.0075 0.0043 0.0037
Loa Loa (eye worm) hypothetical protein 0.0053 0.0019 0.002
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 2 0.0099 0.0068 0.487
Plasmodium falciparum tyrosine kinase-like protein 0.0044 0.0009 0.1813
Trypanosoma brucei eukaryotic translation initiation factor 2-alpha kinase 2 0.0099 0.0068 0.487
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Leishmania major hypothetical protein, conserved 0.0044 0.0009 0.0669
Loa Loa (eye worm) hypothetical protein 0.0044 0.0009 0.0009
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0054 0.002 0.1882
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0055 0.005
Plasmodium vivax serine/threonine protein kinase, putative 0.0099 0.0068 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Brugia malayi Protein kinase domain containing protein 0.0053 0.0019 0.0019
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Leishmania major protein kinase, putative 0.0077 0.0044 0.3165
Schistosoma mansoni tyrosine kinase 0.0053 0.0019 0.0012
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0044 0.0009 0.0029
Echinococcus granulosus peroxidasin 0.0075 0.0043 0.0139
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0087 0.0055 0.7058
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0009 0.0896
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0044 0.0009 0.0009
Echinococcus granulosus epidermal growth factor receptor 0.2549 0.2678 0.8838
Schistosoma mansoni tyrosine kinase 0.1397 0.1451 0.1516
Loa Loa (eye worm) hypothetical protein 0.0146 0.0118 0.0123
Brugia malayi protein kinase C II. 0.0102 0.0072 0.0071
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0133 0.0105 0.0344
Loa Loa (eye worm) WNK protein kinase 0.02 0.0175 0.0183
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Schistosoma mansoni tyrosine kinase 0.1073 0.1106 0.1152
Schistosoma mansoni tyrosine kinase 0.0044 0.0009 0.0002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0234 0.0212 0.0222
Echinococcus multilocularis activated cdc42 kinase 1 0.0044 0.0009 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0017 0.1669
Schistosoma mansoni kinase 0.0084 0.0052 0.0047
Onchocerca volvulus 0.0188 0.0163 0.0532
Echinococcus granulosus tyrosine protein kinase Fyn 0.0088 0.0057 0.0185
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0042 0.0008 0.0023
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Onchocerca volvulus 0.0147 0.012 0.0389
Trypanosoma cruzi cdc2-related kinase 1 0.0079 0.0046 0.3292
Echinococcus multilocularis mitogen activated protein kinase 0.0087 0.0055 0.018
Echinococcus multilocularis tyrosine protein kinase HCK 0.0075 0.0043 0.0138
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) hypothetical protein 0.0042 0.0008 0.0007
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0087 0.0055 0.0179
Loa Loa (eye worm) hypothetical protein 0.0075 0.0043 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0117 0.0114
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0077 0.0044 0.0145
Trypanosoma brucei developmentally regulated phosphoprotein 0.0127 0.0098 0.698
Onchocerca volvulus 0.0053 0.0019 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0009 0.0896
Loa Loa (eye worm) AGC/PKN protein kinase 0.0362 0.0348 0.0365
Echinococcus granulosus tyrosine protein kinase csk 0.0044 0.0009 0.0029
Echinococcus granulosus Immunoglobulin 0.0146 0.0118 0.0388
Loa Loa (eye worm) hypothetical protein 0.0146 0.0118 0.0123
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0079 0.0046 0.592
Loa Loa (eye worm) TK/Met protein kinase 0.0044 0.0009 0.0009
Schistosoma mansoni titin 0.0066 0.0033 0.0027
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0088 0.0057 0.0185
Entamoeba histolytica hypothetical protein 0.0044 0.0009 0.0896
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0079 0.0046 0.0048
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0088 0.0057 0.0185
Echinococcus granulosus retinal guanylyl cyclase 2 0.0044 0.0009 0.0029
Echinococcus granulosus cyclin dependent kinase 5 0.0079 0.0046 0.0151
Entamoeba histolytica tyrosine kinase, putative 0.0044 0.0009 0.0896
Loa Loa (eye worm) TK protein kinase 0.0044 0.0009 0.0009
Echinococcus granulosus c src tyrosine kinase 0.0057 0.0024 0.0076
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1441 0.1498 0.4943
Loa Loa (eye worm) hypothetical protein 0.0147 0.012 0.0125
Echinococcus multilocularis serine threonine protein kinase 0.013 0.0101 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0009 0.0896
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0044 0.0009 0.0029
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0044 0.0009 0.0896
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0044 0.0009 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Echinococcus multilocularis protein tyrosine kinase 0.0044 0.0009 0.0029
Brugia malayi Protein kinase domain containing protein 0.0044 0.0009 0.0009
Entamoeba histolytica hypothetical protein, conserved 0.0044 0.0009 0.0896
Echinococcus granulosus protein tyrosine kinase 0.0044 0.0009 0.0029
Schistosoma mansoni protein kinase 0.0044 0.0009 0.0002
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0133 0.0105 0.7463
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Entamoeba histolytica hypothetical protein 0.0044 0.0009 0.0896
Echinococcus multilocularis Immunoglobulin 0.0146 0.0118 0.0388
Echinococcus granulosus tyrosine kinase 0.0053 0.0019 0.0062
Brugia malayi Protein kinase domain containing protein 0.0053 0.0019 0.0019
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0044 0.0009 0.0896
Schistosoma mansoni protein kinase 0.0077 0.0044 0.0039
Loa Loa (eye worm) hypothetical protein 0.0046 0.0011 0.0011
Entamoeba histolytica serine/threonine kinase, putative 0.0044 0.0009 0.0896
Entamoeba histolytica protein kinase, putative 0.0044 0.0009 0.0896
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Trypanosoma brucei cdc2-related kinase 3 0.0079 0.0046 0.3292
Loa Loa (eye worm) CAMK protein kinase 0.0066 0.0033 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0202 0.0204
Trichomonas vaginalis TK family protein kinase 0.0044 0.0009 0.0896
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0127 0.0098 0.0322
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0916 0.0938 0.0984
Loa Loa (eye worm) hypothetical protein 0.0146 0.0118 0.0123
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0167 0.014 1
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) TK/DDR protein kinase 0.0044 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0146 0.0118 0.0123
Echinococcus multilocularis neuroglian 0.0179 0.0153 0.0504
Trichomonas vaginalis TKL family protein kinase 0.0044 0.0009 0.0896
Loa Loa (eye worm) TK/ALK protein kinase 0.0295 0.0277 0.029
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0055 0.526
Echinococcus multilocularis roundabout 2 0.0075 0.0043 0.0139
Echinococcus granulosus tyrosine protein kinase Fyn 0.0088 0.0057 0.0185
Loa Loa (eye worm) hypothetical protein 0.0075 0.0043 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0009 0.0896
Leishmania major protein kinase, putative,eukaryotic translation initiation factor 2-alpha kinase precursor, putative 0.0099 0.0068 0.487
Trypanosoma cruzi cdc2-related kinase 3 0.0079 0.0046 0.3292
Echinococcus granulosus roundabout 2 0.0221 0.0198 0.0653

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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