Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Pre-SET motif family protein | 0.0066 | 0.0171 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0296 | 0.046 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0126 | 0.034 |
Echinococcus granulosus | importin subunit beta 1 | 0.0123 | 0.0396 | 0.0396 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.006 | 0.0147 | 0.0147 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.006 | 0.0147 | 0.0388 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.0085 | 0.0132 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.024 | 0.0865 | 0.0865 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0068 | 0.0106 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0236 | 0.0848 | 0.0848 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0401 | 0.1503 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0138 | 0.0456 | 0.7009 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.0201 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0178 | 0.0277 |
Echinococcus multilocularis | Peptidase C54 | 0.0062 | 0.0156 | 0.0156 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.006 | 0.0147 | 0.0388 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0187 | 0.0651 | 0.5112 |
Loa Loa (eye worm) | hypothetical protein | 0.112 | 0.4369 | 0.6797 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.009 | 0.0267 | 0.0725 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0055 | 0.0126 | 0.5 |
Leishmania major | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0062 | 0.0156 | 0.0424 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.095 | 0.3689 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.024 | 0.0865 | 0.0865 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0068 | 0.0106 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.0201 | 0.0313 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.024 | 0.0865 | 0.1346 |
Echinococcus multilocularis | muscleblind protein | 0.112 | 0.4369 | 0.4369 |
Entamoeba histolytica | peptidase, C54 family | 0.0024 | 0.0005 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0305 | 0.0474 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0052 | 0.0116 | 0.0181 |
Brugia malayi | Pre-SET motif family protein | 0.0437 | 0.1649 | 0.2566 |
Schistosoma mansoni | jumonji domain containing protein | 0.0486 | 0.1842 | 0.1842 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0057 | 0.0136 | 0.0136 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0118 | 0.0376 | 0.0585 |
Echinococcus multilocularis | jumonji domain containing protein | 0.026 | 0.0942 | 0.0942 |
Giardia lamblia | PHD finger protein 15 | 0.0187 | 0.0651 | 0.3634 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0187 | 0.0651 | 0.5112 |
Echinococcus multilocularis | peregrin | 0.019 | 0.0665 | 0.0665 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0046 | 0.0093 | 0.0093 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0437 | 0.1649 | 0.2566 |
Schistosoma mansoni | hypothetical protein | 0.1268 | 0.4959 | 0.4959 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0046 | 0.0093 | 0.0093 |
Plasmodium falciparum | importin beta, putative | 0.0123 | 0.0396 | 0.6089 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0055 | 0.0126 | 0.034 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0071 | 0.0192 | 0.0299 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0062 | 0.0156 | 0.0243 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0097 | 0.0296 | 0.0624 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.009 | 0.0267 | 0.0713 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.0201 | 0.0201 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0158 | 0.0537 | 0.0537 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1074 | 0.4186 | 0.6512 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0491 | 0.0764 |
Trichomonas vaginalis | set domain proteins, putative | 0.0497 | 0.1888 | 0.2937 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0052 | 0.0116 | 0.0181 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0068 | 0.0178 | 0.0178 |
Brugia malayi | AF-10 protein | 0.0061 | 0.0151 | 0.0234 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0052 | 0.0116 | 0.0181 |
Plasmodium falciparum | glutathione reductase | 0.0158 | 0.0537 | 0.8245 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0147 | 0.0229 |
Echinococcus multilocularis | muscleblind protein 1 | 0.112 | 0.4369 | 0.4369 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.009 | 0.0267 | 0.0267 |
Plasmodium falciparum | thioredoxin reductase | 0.0055 | 0.0126 | 0.1929 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0055 | 0.0126 | 0.0328 |
Entamoeba histolytica | hypothetical protein | 0.01 | 0.0304 | 0.3256 |
Plasmodium vivax | importin-beta 2, putative | 0.0123 | 0.0396 | 0.6089 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0144 | 0.0482 | 0.0751 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0062 | 0.0156 | 0.0243 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0123 | 0.0396 | 0.1074 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0055 | 0.0126 | 0.0195 |
Toxoplasma gondii | autophagy-related cysteine peptidase atg4, putative | 0.0024 | 0.0005 | 0.0036 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0214 | 0.0762 | 0.1185 |
Entamoeba histolytica | hypothetical protein | 0.0153 | 0.0518 | 0.5555 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0068 | 0.0106 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.009 | 0.0267 | 0.0416 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0061 | 0.0151 | 0.0408 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.006 | 0.0146 | 0.0146 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.009 | 0.0267 | 0.0713 |
Schistosoma mansoni | ets-related | 0.0217 | 0.0772 | 0.0772 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0258 | 0.0933 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1074 | 0.4186 | 0.6512 |
Schistosoma mansoni | hypothetical protein | 0.0061 | 0.0151 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0151 | 0.0235 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0445 | 0.1682 | 0.2616 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0126 | 0.0328 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.007 | 0.0188 | 0.0188 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.01 | 0.0304 | 0.0812 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.024 | 0.0865 | 0.0865 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0147 | 0.0229 |
Brugia malayi | CHE-14 protein | 0.0391 | 0.1465 | 0.2278 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0024 | 0.0038 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0138 | 0.0456 | 0.1226 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0391 | 0.1465 | 0.2278 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0045 | 0.0085 | 0.0116 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0611 | 0.2342 | 0.2342 |
Schistosoma mansoni | gabp alpha | 0.0071 | 0.0192 | 0.0192 |
Plasmodium falciparum | phd finger protein, putative | 0.0187 | 0.0651 | 1 |
Leishmania major | trypanothione reductase | 0.0158 | 0.0537 | 0.1455 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.095 | 0.3689 | 0.574 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0187 | 0.0651 | 0.0651 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0391 | 0.1465 | 0.2278 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0123 | 0.0396 | 0.3113 |
Echinococcus multilocularis | dnaJ subfamily B | 0.2534 | 1 | 1 |
Brugia malayi | glutathione reductase | 0.0158 | 0.0537 | 0.0835 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.009 | 0.0267 | 0.21 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.024 | 0.0865 | 0.0865 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0042 | 0.0077 | 0.0119 |
Brugia malayi | Ets-domain containing protein | 0.0071 | 0.0192 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 0.0762 | 0.1185 |
Echinococcus granulosus | jumonji domain containing 1A | 0.006 | 0.0147 | 0.0147 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.004 | 0.0068 | 0.0105 |
Schistosoma mansoni | ran | 0.009 | 0.0267 | 0.0267 |
Brugia malayi | MH2 domain containing protein | 0.0241 | 0.0868 | 0.1351 |
Brugia malayi | hypothetical protein | 0.0138 | 0.0456 | 0.071 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0068 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0171 | 0.0266 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0042 | 0.0077 | 0.1177 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.0147 | 0.0229 |
Entamoeba histolytica | peptidase, C54 family | 0.0024 | 0.0005 | 0.0049 |
Brugia malayi | hypothetical protein | 0.0153 | 0.0518 | 0.0807 |
Loa Loa (eye worm) | hypothetical protein | 0.0463 | 0.1751 | 0.2725 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.0154 | 0.0154 |
Trypanosoma cruzi | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0062 | 0.0156 | 0.0412 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.095 | 0.3689 | 1 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0445 | 0.1682 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0178 | 0.0178 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0055 | 0.0126 | 0.0195 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0046 | 0.0093 | 0.0093 |
Schistosoma mansoni | cpg binding protein | 0.0188 | 0.0657 | 0.0657 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0214 | 0.0762 | 0.1185 |
Brugia malayi | hypothetical protein | 0.0089 | 0.0262 | 0.0407 |
Brugia malayi | Ets-domain containing protein | 0.0071 | 0.0192 | 0.0299 |
Entamoeba histolytica | peptidase, C54 family | 0.0024 | 0.0005 | 0.0049 |
Plasmodium falciparum | thioredoxin reductase | 0.0158 | 0.0537 | 0.8245 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0401 | 0.1503 | 1 |
Trichomonas vaginalis | helicase, putative | 0.004 | 0.0068 | 0.0106 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.1074 | 0.4186 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0158 | 0.0537 | 0.0537 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0391 | 0.1465 | 0.1465 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0138 | 0.0456 | 0.1237 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.038 | 0.142 | 0.142 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0445 | 0.1682 | 0.2616 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1132 | 0.4416 | 0.687 |
Leishmania major | hypothetical protein, conserved | 0.0138 | 0.0456 | 0.1237 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.004 | 0.0068 | 0.0105 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1074 | 0.4186 | 0.6512 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0158 | 0.0537 | 0.0835 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.0201 | 0.0201 |
Entamoeba histolytica | peptidase, C54 family | 0.0024 | 0.0005 | 0.0049 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0055 | 0.0126 | 0.5 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0144 | 0.0482 | 0.0482 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0153 | 0.0518 | 0.0518 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.0201 | 0.0201 |
Onchocerca volvulus | Alhambra homolog | 0.0187 | 0.0651 | 0.148 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0258 | 0.0933 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0158 | 0.0537 | 0.8245 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0123 | 0.0396 | 0.0396 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0147 | 0.0491 | 0.0764 |
Onchocerca volvulus | 0.0497 | 0.1888 | 0.4462 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0126 | 0.0328 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0178 | 0.0178 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.0201 | 0.0313 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0236 | 0.0848 | 0.0848 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0055 | 0.0126 | 0.0328 |
Plasmodium vivax | hypothetical protein, conserved | 0.0187 | 0.0651 | 1 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.01 | 0.0304 | 0.0473 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0068 | 0.0178 | 0.0178 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.0063 | 0.0961 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0241 | 0.0868 | 0.1351 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0055 | 0.0126 | 0.1929 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0066 | 0.0171 | 0.0171 |
Onchocerca volvulus | 0.0078 | 0.0219 | 0.0439 | |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0055 | 0.0126 | 0.034 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.003 | 0.0047 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1637 | 0.6428 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1637 | 0.6428 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0138 | 0.0456 | 0.3583 |
Schistosoma mansoni | hypothetical protein | 0.0153 | 0.0518 | 0.0518 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0126 | 0.0328 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0055 | 0.0126 | 0.0986 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.009 | 0.0267 | 0.0267 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0068 | 0.0178 | 0.0277 |
Plasmodium vivax | JmjC domain containing protein | 0.006 | 0.0147 | 0.2266 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0401 | 0.1503 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.0201 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0156 | 0.0243 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0391 | 0.1465 | 0.1465 |
Plasmodium vivax | SET domain protein, putative | 0.0066 | 0.0171 | 0.2622 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0055 | 0.0126 | 0.0389 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0158 | 0.0537 | 0.1444 |
Brugia malayi | CXXC zinc finger family protein | 0.0178 | 0.0616 | 0.0959 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0178 | 0.0178 |
Brugia malayi | Fli-1 protein | 0.0217 | 0.0772 | 0.1201 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0401 | 0.1503 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0057 | 0.0136 | 0.0136 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0066 | 0.0171 | 0.0171 |
Brugia malayi | Muscleblind-like protein | 0.112 | 0.4369 | 0.6797 |
Echinococcus multilocularis | cysteine protease atg4b | 0.0062 | 0.0156 | 0.0156 |
Echinococcus granulosus | cpg binding protein | 0.0188 | 0.0657 | 0.0657 |
Schistosoma mansoni | cpg binding protein | 0.0188 | 0.0657 | 0.0657 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0055 | 0.0126 | 0.1929 |
Brugia malayi | hypothetical protein | 0.01 | 0.0305 | 0.0474 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0042 | 0.0077 | 0.0602 |
Echinococcus multilocularis | GPCR, family 2 | 0.0068 | 0.0178 | 0.0178 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0061 | 0.0151 | 0.1182 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.009 | 0.0267 | 0.1265 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0305 | 0.0474 |
Schistosoma mansoni | protein phosphatase 2C | 0.006 | 0.0147 | 0.0147 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0491 | 0.0491 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.006 | 0.0147 | 0.1158 |
Schistosoma mansoni | eyes absent homolog | 0.01 | 0.0305 | 0.0305 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0126 | 0.0328 |
Brugia malayi | Phospholipase A2 family protein | 0.0097 | 0.0296 | 0.046 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.0063 | 0.067 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0126 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.0396 | 0.0617 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0055 | 0.0126 | 0.0328 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0052 | 0.0116 | 0.0181 |
Brugia malayi | jmjC domain containing protein | 0.0236 | 0.0848 | 0.1319 |
Echinococcus multilocularis | protein patched | 0.0391 | 0.1465 | 0.1465 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.036 | 0.1343 | 0.8837 |
Trypanosoma brucei | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0062 | 0.0156 | 0.0424 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0055 | 0.0126 | 0.034 |
Plasmodium falciparum | cysteine protease ATG4, putative | 0.0024 | 0.0005 | 0.007 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0123 | 0.0396 | 0.1074 |
Schistosoma mansoni | hypothetical protein | 0.2534 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0187 | 0.0651 | 0.0651 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.009 | 0.0267 | 0.0416 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0913 | 0.3544 | 0.3544 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.006 | 0.0147 | 0.0147 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.014 | 0.0466 | 0.0466 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0138 | 0.0456 | 0.7009 |
Echinococcus multilocularis | protein dispatched 1 | 0.0391 | 0.1465 | 0.1465 |
Echinococcus multilocularis | phd:f box containing protein | 0.006 | 0.0147 | 0.0147 |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.0072 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.0456 | 0.071 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.036 | 0.1343 | 0.8837 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.0147 | 0.0229 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0055 | 0.0126 | 0.1929 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.095 | 0.3689 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0066 | 0.0171 | 0.0171 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.024 | 0.0865 | 0.0865 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0042 | 0.0077 | 0.0602 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0024 | 0.0038 |
Brugia malayi | Bromodomain containing protein | 0.019 | 0.0665 | 0.1035 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0055 | 0.0126 | 0.034 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0055 | 0.0126 | 0.034 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.0147 | 0.0229 |
Loa Loa (eye worm) | histone methyltransferase | 0.0057 | 0.0136 | 0.0211 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.095 | 0.3689 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0158 | 0.0537 | 0.8245 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.0651 | 0.1013 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0147 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0037 | 0.0057 |
Echinococcus granulosus | GPCR family 2 | 0.0068 | 0.0178 | 0.0178 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1074 | 0.4186 | 0.6512 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.006 | 0.0147 | 0.0147 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0178 | 0.0616 | 0.0959 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0147 | 0.0229 |
Brugia malayi | Importin beta-1 subunit | 0.0123 | 0.0396 | 0.0617 |
Brugia malayi | Peptidase family C54 containing protein | 0.0062 | 0.0156 | 0.0243 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.006 | 0.0147 | 0.1158 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.006 | 0.0147 | 0.2266 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0187 | 0.0651 | 0.1013 |
Entamoeba histolytica | hypothetical protein | 0.0153 | 0.0518 | 0.5555 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0068 | 0.0106 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0028 | 0.0018 | 0.0018 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.095 | 0.3689 | 0.3689 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0107 | 0.0336 | 0.0336 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.006 | 0.0147 | 0.0147 |
Toxoplasma gondii | thioredoxin reductase | 0.0158 | 0.0537 | 0.4215 |
Schistosoma mansoni | ran | 0.009 | 0.0267 | 0.0267 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0062 | 0.0154 | 0.0154 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0042 | 0.0065 |
Entamoeba histolytica | peptidase, C54 family | 0.0062 | 0.0156 | 0.1675 |
Loa Loa (eye worm) | acetyltransferase | 0.0144 | 0.0482 | 0.0751 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0445 | 0.1682 | 0.2616 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0062 | 0.0156 | 0.0243 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1637 | 0.6428 | 1 |
Brugia malayi | PHD-finger family protein | 0.0187 | 0.0651 | 0.1013 |
Brugia malayi | PHD-finger family protein | 0.0071 | 0.0191 | 0.0297 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.0147 | 0.0229 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0236 | 0.0848 | 0.1319 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0144 | 0.0482 | 0.0482 |
Schistosoma mansoni | cpg binding protein | 0.0178 | 0.0616 | 0.0616 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0042 | 0.0077 | 0.0077 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0062 | 0.0156 | 0.0243 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0055 | 0.0126 | 0.1929 |
Onchocerca volvulus | 0.0178 | 0.0616 | 0.1397 | |
Entamoeba histolytica | Ran family GTPase | 0.009 | 0.0267 | 0.2864 |
Schistosoma mansoni | autophagin-1 (C54 family) | 0.0062 | 0.0156 | 0.0156 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0611 | 0.2342 | 0.2342 |
Loa Loa (eye worm) | glutathione reductase | 0.0158 | 0.0537 | 0.0835 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0191 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.1182 | 0.1839 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0066 | 0.0171 | 0.0171 |
Entamoeba histolytica | hypothetical protein | 0.0153 | 0.0518 | 0.5555 |
Schistosoma mansoni | hypothetical protein | 0.1268 | 0.4959 | 0.4959 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.007 | 0.0188 | 0.0188 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0066 | 0.0171 | 0.134 |
Treponema pallidum | NADH oxidase | 0.0055 | 0.0126 | 0.5 |
Echinococcus granulosus | geminin | 0.1268 | 0.4959 | 0.4959 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0055 | 0.0126 | 0.034 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0066 | 0.0171 | 0.0171 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.036 | 0.1343 | 0.8837 |
Brugia malayi | Thioredoxin reductase | 0.0158 | 0.0537 | 0.0835 |
Echinococcus granulosus | Peptidase C54 | 0.0062 | 0.0156 | 0.0156 |
Echinococcus granulosus | jumonji domain containing protein | 0.026 | 0.0942 | 0.0942 |
Loa Loa (eye worm) | fli-1 protein | 0.0217 | 0.0772 | 0.1201 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0241 | 0.0868 | 0.1351 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0062 | 0.0154 | 0.0154 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0061 | 0.0151 | 0.0408 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.024 | 0.0865 | 0.1346 |
Plasmodium falciparum | glutathione reductase | 0.0055 | 0.0126 | 0.1929 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.024 | 0.0865 | 0.0865 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0463 | 0.1751 | 0.4132 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0055 | 0.0126 | 0.0126 |
Echinococcus granulosus | peregrin | 0.019 | 0.0665 | 0.0665 |
Loa Loa (eye worm) | hypothetical protein | 0.095 | 0.3689 | 0.574 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0055 | 0.0126 | 0.0126 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0052 | 0.0116 | 0.0181 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.1637 | 0.6428 | 1 |
Schistosoma mansoni | phd/f-box containing protein | 0.006 | 0.0147 | 0.0147 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C54, putative | 0.0024 | 0.0005 | 0.0012 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0078 | 0.0219 | 0.0219 |
Schistosoma mansoni | hypothetical protein | 0.131 | 0.5126 | 0.5126 |
Schistosoma mansoni | family C54 unassigned peptidase (C54 family) | 0.0062 | 0.0156 | 0.0156 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.0085 | 0.0132 |
Echinococcus multilocularis | snurportin 1 | 0.131 | 0.5126 | 0.5126 |
Schistosoma mansoni | family C54 unassigned peptidase (C54 family) | 0.0062 | 0.0156 | 0.0156 |
Echinococcus multilocularis | cpg binding protein | 0.0188 | 0.0657 | 0.0657 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0391 | 0.1465 | 0.1465 |
Echinococcus multilocularis | geminin | 0.1268 | 0.4959 | 0.4959 |
Brugia malayi | RNA, U transporter 1 | 0.0349 | 0.1298 | 0.2019 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.0072 | 0.0194 | 0.2976 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.1637 | 0.6428 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0343 | 0.1273 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1074 | 0.4186 | 0.6512 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0072 | 0.0112 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1637 | 0.6428 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0611 | 0.2342 | 0.3644 |
Plasmodium vivax | hypothetical protein, conserved | 0.0072 | 0.0194 | 0.2976 |
Loa Loa (eye worm) | hypothetical protein | 0.0391 | 0.1465 | 0.2278 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.036 | 0.1343 | 0.8837 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1074 | 0.4186 | 0.6512 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0214 | 0.0762 | 0.1185 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0074 | 0.0201 | 0.0313 |
Leishmania major | hypothetical protein, conserved | 0.006 | 0.0147 | 0.04 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.095 | 0.3689 | 0.3689 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0147 | 0.0229 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0391 | 0.1465 | 0.1465 |
Trichomonas vaginalis | importin beta-1, putative | 0.01 | 0.0304 | 0.0473 |
Echinococcus granulosus | cysteine protease atg4b | 0.0062 | 0.0156 | 0.0156 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.006 | 0.0147 | 0.0147 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.009 | 0.0267 | 0.4107 |
Trichomonas vaginalis | ran, putative | 0.009 | 0.0267 | 0.0416 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0071 | 0.0192 | 0.0192 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.131 | 0.5126 | 0.7975 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0391 | 0.1465 | 0.1465 |
Entamoeba histolytica | hypothetical protein | 0.0153 | 0.0518 | 0.5555 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.095 | 0.3689 | 0.3689 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0153 | 0.0518 | 0.0518 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0062 | 0.0156 | 0.0243 |
Schistosoma mansoni | jumonji domain containing protein | 0.006 | 0.0147 | 0.0147 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.009 | 0.0267 | 0.4107 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0126 | 0.0328 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.006 | 0.0147 | 0.0147 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0055 | 0.0126 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1132 | 0.4416 | 0.687 |
Schistosoma mansoni | phosphatidylserine receptor | 0.006 | 0.0147 | 0.0147 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0187 | 0.0651 | 0.0651 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0138 | 0.0456 | 0.7009 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0068 | 0.0106 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0034 | 0.0042 | 0.0065 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0068 | 0.0106 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0391 | 0.1465 | 0.1465 |
Brugia malayi | Heterochromatin protein 1 | 0.0074 | 0.0201 | 0.0313 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0226 | 0.0807 | 0.0807 |
Schistosoma mansoni | importin beta-1 | 0.0123 | 0.0396 | 0.0396 |
Leishmania major | importin beta-1 subunit, putative | 0.01 | 0.0304 | 0.0824 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0055 | 0.0126 | 0.0126 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1637 | 0.6428 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0068 | 0.0178 | 0.0277 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.006 | 0.0147 | 0.04 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1637 | 0.6428 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.036 | 0.1343 | 0.8837 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0068 | 0.0178 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0258 | 0.0933 | 0.1452 |
Echinococcus granulosus | snurportin 1 | 0.131 | 0.5126 | 0.5126 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0178 | 0.0178 |
Trypanosoma brucei | trypanothione reductase | 0.0158 | 0.0537 | 0.1455 |
Toxoplasma gondii | WD domain, G-beta repeat-containing protein | 0.0061 | 0.0151 | 0.1182 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0068 | 0.0106 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0138 | 0.0456 | 0.1226 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.024 | 0.0865 | 0.0865 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0042 | 0.0077 | 0.0119 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0052 | 0.0116 | 0.0181 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0385 | 0.1443 | 0.2244 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0068 | 0.0178 | 0.0178 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0052 | 0.0116 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0072 | 0.0112 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.0201 | 0.0201 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0126 | 0.034 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0055 | 0.0126 | 0.0195 |
Leishmania major | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0024 | 0.0005 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.112 | 0.4369 | 0.6797 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.095 | 0.3689 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0052 | 0.0116 | 0.0181 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0066 | 0.0171 | 0.0171 |
Echinococcus granulosus | phd:f box containing protein | 0.006 | 0.0147 | 0.0147 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0055 | 0.0126 | 0.0986 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0071 | 0.0192 | 0.0192 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0046 | 0.0093 | 0.0093 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1074 | 0.4186 | 0.6512 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0153 | 0.0518 | 0.0518 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0187 | 0.0651 | 0.0651 |
Echinococcus granulosus | muscleblind protein | 0.112 | 0.4369 | 0.4369 |
Leishmania major | GTP-binding protein, putative | 0.009 | 0.0267 | 0.0725 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0072 | 0.0112 |
Schistosoma mansoni | patched 1 | 0.0391 | 0.1465 | 0.1465 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0068 | 0.0178 | 0.0178 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0236 | 0.0848 | 0.0848 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0158 | 0.0537 | 0.2985 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0072 | 0.0086 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0068 | 0.0106 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.01 | 0.0304 | 0.0473 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.036 | 0.1343 | 0.8837 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.