Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0077 | 0.0108 | 0.0108 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0271 | 0.049 | 0.049 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0271 | 0.049 | 0.049 |
Brugia malayi | Peptidase family M1 containing protein | 0.0271 | 0.049 | 0.1071 |
Onchocerca volvulus | 0.0271 | 0.049 | 0.5 | |
Loa Loa (eye worm) | aminopeptidase N | 0.0271 | 0.049 | 0.049 |
Onchocerca volvulus | 0.0271 | 0.049 | 0.5 | |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0271 | 0.049 | 0.5 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0271 | 0.049 | 0.5 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0271 | 0.049 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.51 | 1 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0271 | 0.049 | 0.049 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0271 | 0.049 | 0.049 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0084 | 0.0122 | 0.0122 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0271 | 0.049 | 0.049 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0271 | 0.049 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0088 | 0.0088 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0271 | 0.049 | 0.049 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0271 | 0.049 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0271 | 0.049 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0271 | 0.049 | 1 |
Brugia malayi | hypothetical protein | 0.2345 | 0.4574 | 1 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0271 | 0.049 | 0.049 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0271 | 0.049 | 0.5 |
Echinococcus granulosus | aminopeptidase N | 0.0271 | 0.049 | 0.049 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0271 | 0.049 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0271 | 0.049 | 0.1071 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0271 | 0.049 | 0.5 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0077 | 0.0108 | 0.0108 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0271 | 0.049 | 0.5 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0077 | 0.0108 | 0.0236 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0077 | 0.0108 | 0.0108 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0271 | 0.049 | 0.049 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0271 | 0.049 | 0.049 |
Brugia malayi | Peptidase family M1 containing protein | 0.0271 | 0.049 | 0.1071 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0271 | 0.049 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0271 | 0.049 | 0.049 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0271 | 0.049 | 0.049 |
Toxoplasma gondii | aminopeptidase N protein | 0.0271 | 0.049 | 0.5 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0271 | 0.049 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0271 | 0.049 | 0.049 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0271 | 0.049 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0271 | 0.049 | 0.049 |
Brugia malayi | TATA binding protein associated factor | 0.0271 | 0.049 | 0.1071 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0271 | 0.049 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0271 | 0.049 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0271 | 0.049 | 0.049 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0271 | 0.049 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0271 | 0.049 | 0.5 |
Trypanosoma brucei | aminopeptidase, putative | 0.0271 | 0.049 | 0.5 |
Onchocerca volvulus | 0.0271 | 0.049 | 0.5 | |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0271 | 0.049 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0271 | 0.049 | 0.5 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0271 | 0.049 | 0.5 |
Entamoeba histolytica | aminopeptidase, putative | 0.0271 | 0.049 | 0.5 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.51 | 1 | 1 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0271 | 0.049 | 0.5 |
Brugia malayi | hypothetical protein | 0.0271 | 0.049 | 0.1071 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0271 | 0.049 | 0.5 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0271 | 0.049 | 0.5 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0271 | 0.049 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0271 | 0.049 | 0.049 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0271 | 0.049 | 0.049 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0271 | 0.049 | 0.049 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0084 | 0.0122 | 0.0122 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0271 | 0.049 | 0.049 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0271 | 0.049 | 0.5 |
Brugia malayi | hypothetical protein | 0.0271 | 0.049 | 0.1071 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0271 | 0.049 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0271 | 0.049 | 0.049 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0271 | 0.049 | 0.049 |
Echinococcus multilocularis | aminopeptidase N | 0.0271 | 0.049 | 0.049 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.51 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.