Detailed information for compound 877956

Basic information

Technical information
  • TDR Targets ID: 877956
  • Name: 7-[3-(3,4-dimethylphenoxy)-2-hydroxypropyl]-8 -(3-hydroxypropylamino)-1,3-dimethylpurine-2, 6-dione
  • MW: 431.485 | Formula: C21H29N5O5
  • H donors: 3 H acceptors: 5 LogP: 1.82 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCCNc1nc2c(n1CC(COc1ccc(c(c1)C)C)O)c(=O)n(c(=O)n2C)C
  • InChi: 1S/C21H29N5O5/c1-13-6-7-16(10-14(13)2)31-12-15(28)11-26-17-18(23-20(26)22-8-5-9-27)24(3)21(30)25(4)19(17)29/h6-7,10,15,27-28H,5,8-9,11-12H2,1-4H3,(H,22,23)
  • InChiKey: UUKBTPMVNCPRHB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 7-[3-(3,4-dimethylphenoxy)-2-hydroxy-propyl]-8-(3-hydroxypropylamino)-1,3-dimethyl-purine-2,6-dione
  • 7-[3-(3,4-dimethylphenoxy)-2-hydroxy-propyl]-8-(3-hydroxypropylamino)-1,3-dimethyl-xanthine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus granulosus serotonin receptor 0.0129 0.0568 0.0619
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0129 0.0568 0.056
Loa Loa (eye worm) AGC/PKA protein kinase 0.004 0.0133 0.0145
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0085 0.014
Brugia malayi Uncoordinated protein 44 0.0014 0.0009 0.000000009863
Brugia malayi neuropeptide F receptor 0.0129 0.0568 0.056
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0099 0.0108
Schistosoma mansoni biogenic amine (5HT) receptor 0.0129 0.0568 0.1027
Brugia malayi PXA domain containing protein 0.0019 0.0031 0.0023
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.1136 0.5457 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.008 0.0313
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0455 0.0496
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0455 0.0819
Echinococcus multilocularis rho guanine nucleotide exchange factor 16 0.0018 0.0029 0.0031
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0468 0.2212 0.4043
Brugia malayi G-protein coupled receptor 0.0129 0.0568 0.056
Onchocerca volvulus Neuropeptide F receptor homolog 0.0129 0.0568 0.5335
Echinococcus multilocularis G-protein coupled receptor, putative 0.0129 0.0568 0.0619
Brugia malayi hypothetical protein 0.0129 0.0568 0.056
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0129 0.0568 0.1027
Schistosoma mansoni histamine h1 receptor 0.0129 0.0568 0.1027
Brugia malayi hypothetical protein 0.0129 0.0568 0.056
Trichomonas vaginalis conserved hypothetical protein 0.0468 0.2212 0.8747
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0228 0.0385
Echinococcus granulosus geminin 0.0165 0.0742 0.0808
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.004 0.0133 0.0211
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.008 0.0313
Onchocerca volvulus 0.003 0.0085 0.0793
Mycobacterium leprae Probable pyruvate kinase PykA 0.0032 0.0099 0.1931
Onchocerca volvulus Rho guanine nucleotide exchange factor 3 homolog 0.0018 0.0029 0.0269
Entamoeba histolytica PH domain containing protein kinase, putative 0.004 0.0133 0.2444
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0228 0.4283
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0031 0.0034
Brugia malayi neuropeptide F receptor 0.0129 0.0568 0.056
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.004 0.0133 0.0243
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0031 0.0034
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Brugia malayi 6-phosphofructokinase 0.0106 0.0455 0.0446
Schistosoma mansoni biogenic amine (5HT) receptor 0.0129 0.0568 0.1027
Echinococcus multilocularis lamin dm0 0.0026 0.0068 0.0074
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0009 0.0001
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0184 0.0336
Brugia malayi hypothetical protein 0.0129 0.0568 0.056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.0032
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0129 0.0568 0.0619
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.0032
Loa Loa (eye worm) glutathione reductase 0.0046 0.0164 0.0179
Echinococcus granulosus tm gpcr rhodopsin 0.0129 0.0568 0.0619
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0029 0.002
Onchocerca volvulus 0.0026 0.0068 0.0637
Loa Loa (eye worm) neuropeptide F receptor 0.0129 0.0568 0.0619
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0095 0.3661
Echinococcus granulosus neuropeptide receptor 0.0129 0.0568 0.0619
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0036 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Schistosoma mansoni hypothetical protein 0.0165 0.0742 0.1346
Trichomonas vaginalis rotamase, putative 0.0033 0.0099 0.0388
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0184 0.0725
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0018 0.1807
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0031 0.0042
Onchocerca volvulus 0.0129 0.0568 0.5335
Echinococcus multilocularis Niemann Pick C1 protein 0.0468 0.2212 0.241
Leishmania major hypothetical protein, conserved 0.0018 0.0029 0.0052
Echinococcus granulosus expressed protein 0.0033 0.0099 0.0107
Onchocerca volvulus 0.0018 0.0029 0.0269
Brugia malayi phosphofructokinase 0.0106 0.0455 0.0446
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.1136 0.5457 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Trichomonas vaginalis AGC family protein kinase 0.004 0.0133 0.0525
Leishmania major paraflagellar rod protein-like protein 0.0018 0.0029 0.0052
Loa Loa (eye worm) hypothetical protein 0.0032 0.0099 0.0107
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0111 0.0102
Onchocerca volvulus 0.0129 0.0568 0.5335
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0031 0.0042
Loa Loa (eye worm) hypothetical protein 0.0026 0.0066 0.0072
Schistosoma mansoni biogenic amine receptor 0.0129 0.0568 0.1027
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Brugia malayi hypothetical protein 0.0129 0.0568 0.056
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0455 1
Echinococcus multilocularis neuropeptide receptor 0.0129 0.0568 0.0619
Schistosoma mansoni microtubule-associated protein tau 0.0672 0.3204 0.5865
Leishmania major pyruvate kinase 0.0032 0.0099 0.018
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0455 0.0819
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0184 0.02
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.004 0.0133 0.0145
Brugia malayi PXA domain containing protein 0.0019 0.0031 0.0023
Brugia malayi hypothetical protein 0.0019 0.0031 0.0023
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.0508 1
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0009 0.0009
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0036 0.0039
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0228 0.0402
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0184 0.02
Brugia malayi hypothetical protein 0.0129 0.0568 0.056
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.0455 1
Schistosoma mansoni neuropeptide F-like receptor 0.0129 0.0568 0.1027
Brugia malayi G protein-coupled receptor 0.0129 0.0568 0.056
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0018 0.0029 0.0032
Onchocerca volvulus 0.0129 0.0568 0.5335
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0031 0.0122
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Onchocerca volvulus 0.0129 0.0568 0.5335
Brugia malayi Protein kinase domain containing protein 0.0015 0.0013 0.0004
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0018 0.001
Schistosoma mansoni alpha-1 adrenergic receptor 0.0129 0.0568 0.1027
Leishmania major protein kinase A catalytic subunit 0.004 0.0133 0.0243
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0568 0.1027
Echinococcus multilocularis expressed protein 0.0364 0.1706 0.1859
Echinococcus multilocularis g protein coupled receptor 0.0129 0.0568 0.0619
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0032 0.0026
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.008 0.4201
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0129 0.0568 0.056
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0036 0.005
Echinococcus multilocularis protein kinase C and casein kinase substrate in 0.0018 0.0029 0.0031
Brugia malayi Cytochrome P450 family protein 0.0019 0.0032 0.0024
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.0508 1
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0031 0.0023
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus granulosus LIM and SH3 domain protein 1 0.0018 0.0029 0.0031
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0032
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0031 0.0023
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0533 0.2528 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0129 0.0568 0.0619
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0031 0.0034
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0009 0.0077
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Echinococcus multilocularis expressed protein 0.0033 0.0099 0.0107
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Brugia malayi Tachykinin-like peptides receptor 99D 0.0129 0.0568 0.056
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0455 0.0832
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0234 0.0413
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.008 0.8073
Schistosoma mansoni lamin 0.0026 0.0068 0.0109
Echinococcus granulosus neuropeptide Y receptor 0.0129 0.0568 0.0619
Leishmania major peroxin 13, putative;with=GeneDB:Tb927.10.14720 0.0018 0.0029 0.0052
Trichomonas vaginalis set domain proteins, putative 0.0231 0.1064 0.4206
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0031 0.0023
Schistosoma mansoni neuropeptide receptor 0.0129 0.0568 0.1027
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0289 0.0314
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0077 0.0083
Echinococcus granulosus microtubule associated protein 2 0.0672 0.3204 0.3491
Echinococcus granulosus fmrfamide receptor 0.0129 0.0568 0.0619
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0133 0.0228
Onchocerca volvulus 0.0129 0.0568 0.5335
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0032 0.0035
Echinococcus multilocularis pyruvate kinase 0.0017 0.0022 0.0023
Echinococcus granulosus sh3 containing grb2 protein 3 0.0018 0.0029 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0029 0.0113
Brugia malayi Pre-SET motif family protein 0.0203 0.0928 0.092
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0228 0.0402
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0036 0.0038
Schistosoma mansoni amine GPCR 0.0129 0.0568 0.1027
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.008 0.0313
Onchocerca volvulus 0.0028 0.0077 0.0715
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0031 0.0042
Brugia malayi hypothetical protein 0.0129 0.0568 0.056
Echinococcus multilocularis pyruvate kinase 0.0026 0.0065 0.0071
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0029 0.002
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0031 0.0042
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0099 0.0388
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0005 0.0008
Echinococcus multilocularis fmrfamide receptor 0.0129 0.0568 0.0619
Echinococcus multilocularis serotonin receptor 0.0129 0.0568 0.0619
Schistosoma mansoni hypothetical protein 0.0165 0.0742 0.1346
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0032
Echinococcus multilocularis neuropeptide Y receptor 0.0129 0.0568 0.0619
Echinococcus granulosus lamin dm0 0.0026 0.0068 0.0074
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0184 0.0725
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus multilocularis transfer RNA-Thr 0.1903 0.9176 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0129 0.0568 0.0619
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0031 0.0034
Brugia malayi CHE-14 protein 0.0468 0.2212 0.2205
Brugia malayi Pyruvate kinase, M2 isozyme 0.0032 0.0099 0.009
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0085 0.0092
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0029 0.002
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0032 0.0058
Trichomonas vaginalis p67phox protein, putative 0.0018 0.0029 0.0113
Brugia malayi G protein-coupled receptor F59B2.13 0.0129 0.0568 0.056
Onchocerca volvulus 0.0035 0.0111 0.1038
Echinococcus granulosus intersectin 2 0.0018 0.0029 0.0031
Echinococcus multilocularis tumor protein p63 0.0329 0.1539 0.1676
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0022 0.0166
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0171 0.0187
Echinococcus multilocularis neuropeptide receptor A26 0.0577 0.2744 0.299
Brugia malayi Protein kinase domain containing protein 0.1903 0.9176 0.9175
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.008 0.0313
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0184 0.0725
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0031 0.0034
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0085 0.014
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0031 0.0042
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.004 0.0133 0.0145
Brugia malayi G-protein coupled receptor 0.0129 0.0568 0.056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.0032
Plasmodium vivax pyruvate kinase, putative 0.0032 0.0099 0.5493
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.004 0.0133 0.0243
Loa Loa (eye worm) phosphofructokinase 0.0106 0.0455 0.0496
Echinococcus multilocularis NCK adaptor protein 0.0018 0.0029 0.0031
Mycobacterium ulcerans pyruvate kinase 0.0032 0.0099 0.0148
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0129 0.0568 0.1027
Echinococcus multilocularis protein dispatched 1 0.0468 0.2212 0.241
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus granulosus sterol regulatory element binding protein 0.0468 0.2212 0.241
Echinococcus multilocularis orexin receptor type 2 0.0129 0.0568 0.0619
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0184 0.0336
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0111 0.012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0032
Chlamydia trachomatis pyruvate kinase 0.0032 0.0099 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Onchocerca volvulus 0.0018 0.0029 0.0269
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0032 0.0099 0.164
Brugia malayi hypothetical protein 0.0018 0.0029 0.002
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0184 0.7901
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Entamoeba histolytica hypothetical protein 0.0019 0.0031 0.0054
Brugia malayi Pyruvate kinase, muscle isozyme 0.0032 0.0099 0.009
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0037
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.008 0.1186
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0085 0.014
Schistosoma mansoni lamin 0.0026 0.0068 0.0109
Loa Loa (eye worm) hypothetical protein 0.0048 0.0175 0.019
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0031 0.0023
Schistosoma mansoni pyruvate kinase 0.0017 0.0022 0.0024
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Brugia malayi Abl-interactor 1 0.0018 0.0029 0.002
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0029 0.002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0031 0.0042
Echinococcus granulosus alpha 1A adrenergic receptor 0.0129 0.0568 0.0619
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0129 0.0568 0.0619
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0184 0.0305
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0455 1
Loa Loa (eye worm) hypothetical protein 0.0738 0.3525 0.3842
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0095 0.0173
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.008 0.1406
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0184 0.02
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.0928 0.1011
Onchocerca volvulus 0.0026 0.0068 0.0637
Schistosoma mansoni pyruvate kinase 0.0032 0.0099 0.0165
Toxoplasma gondii pyruvate kinase PyK1 0.0032 0.0099 0.3828
Leishmania major pyruvate kinase 0.0032 0.0099 0.018
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0018 0.0029 0.0032
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.1136 0.5457 1
Echinococcus multilocularis geminin 0.0165 0.0742 0.0808
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.004 0.0133 0.7865
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0164 0.0179
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0095 0.0173
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0032
Schistosoma mansoni hematopoietic lineage cell specific protein 0.0018 0.0029 0.0037
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0129 0.0568 0.056
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.0455 0.8956
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0036 0.005
Echinococcus granulosus abl interactor 2 0.0018 0.0029 0.0031
Loa Loa (eye worm) hypothetical protein 0.0309 0.1441 0.157
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0018 0.0029 0.0037
Brugia malayi Variant SH3 domain containing protein 0.0019 0.0034 0.0025
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0228 0.0248
Brugia malayi Dopamine receptor protein 2 0.0129 0.0568 0.056
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0451 0.8878
Echinococcus multilocularis endophilin A3 0.0018 0.0029 0.0031
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0085 0.0092
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0085 0.0092
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Schistosoma mansoni growth hormone secretagogue receptor 0.0129 0.0568 0.1027
Brugia malayi hypoxia-induced factor 1 0.0147 0.0653 0.0645
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0018 0.0032
Onchocerca volvulus 0.0018 0.0029 0.0269
Echinococcus granulosus pyruvate kinase 0.0032 0.0099 0.0107
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.008 0.0313
Echinococcus granulosus rho guanine nucleotide exchange factor 16 0.0018 0.0029 0.0031
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0039 0.0129 0.014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.001
Brugia malayi Pre-SET motif family protein 0.003 0.0085 0.0076
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Echinococcus multilocularis LIM and SH3 domain protein 1 0.0018 0.0029 0.0031
Onchocerca volvulus 0.0129 0.0568 0.5335
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0133 0.0228
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.0032
Echinococcus granulosus single minded 2 0.0035 0.0111 0.012
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0129 0.0568 0.0619
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0099 0.0107
Brugia malayi putative neuropeptide receptor 0.0129 0.0568 0.056
Echinococcus multilocularis protein KINase family member (kin 25) 0.0738 0.3525 0.3842
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0018 0.0029 0.0032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0034
Brugia malayi ORL1-like opioid receptor 0.0129 0.0568 0.056
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0068 0.0074
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.0032
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0009 0.000000018088
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0184 0.0321
Echinococcus multilocularis pyruvate kinase 0.0032 0.0099 0.0107
Brugia malayi hypothetical protein 0.0035 0.0111 0.0102
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0129 0.0568 0.1027
Echinococcus granulosus neuropeptide Y receptor 0.0129 0.0568 0.0619
Entamoeba histolytica hypothetical protein 0.0035 0.0111 0.1921
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0568 0.1027
Echinococcus granulosus Ankyrin 0.0014 0.0009 0.001
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0037
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0031 0.0034
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0164 0.0179
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0095 0.1547
Onchocerca volvulus 0.0048 0.0175 0.1636
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0111 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0122
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0029 0.0052
Loa Loa (eye worm) neuropeptide F receptor 0.0129 0.0568 0.0619
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0738 0.3525 0.3842
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.008 0.0313
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0018 0.0029 0.0037
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0099 0.0921
Echinococcus granulosus RIMS binding protein 2 0.0018 0.0029 0.0031
Brugia malayi intermediate filament protein 0.0026 0.0068 0.006
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0129 0.0568 0.0619
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Giardia lamblia Pyruvate kinase 0.0017 0.0022 0.0014
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0111 0.0187
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0031 0.0034
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.004 0.0133 0.0125
Schistosoma mansoni opsin-like receptor 0.0129 0.0568 0.1027
Schistosoma mansoni biogenic amine receptor 0.0129 0.0568 0.1027
Schistosoma mansoni hypothetical protein 0.0129 0.0568 0.1027
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0018 0.0032
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.0455 0.0832
Schistosoma mansoni neuropeptide receptor 0.0129 0.0568 0.1027
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0129 0.0568 0.0619
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0022 0.0238
Echinococcus granulosus biogenic amine 5HT receptor 0.0129 0.0568 0.0619
Onchocerca volvulus 0.0129 0.0568 0.5335
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0031 0.0042
Brugia malayi sulfakinin receptor protein 0.0129 0.0568 0.056
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0171 0.0297
Echinococcus granulosus g protein coupled receptor 0.0129 0.0568 0.0619
Echinococcus granulosus neuropeptide s receptor 0.0577 0.2744 0.299
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0032 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0034
Brugia malayi AKH receptor 0.0129 0.0568 0.056
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0018 0.5
Entamoeba histolytica PH domain containing protein kinase, putative 0.004 0.0133 0.2444
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0164 0.03
Echinococcus multilocularis sh3 containing grb2 protein 3 0.0018 0.0029 0.0031
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0129 0.0568 0.1027
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0032
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0184 0.066
Schistosoma mansoni myosin xvIII 0.0129 0.0568 0.1027
Echinococcus granulosus growth factor receptor bound protein 2 0.0018 0.0029 0.0031
Entamoeba histolytica hypothetical protein 0.0035 0.0111 0.1921
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.004 0.0133 0.0145
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0129 0.0568 0.0619
Echinococcus granulosus orexin receptor type 2 0.0129 0.0568 0.0619
Brugia malayi 6-phosphofructokinase 0.0106 0.0455 0.0446
Echinococcus granulosus neuropeptide receptor A26 0.0577 0.2744 0.299
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0129 0.0568 0.0619
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0018 0.0032
Echinococcus multilocularis dro:myosuppressin receptor 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0023 0.0051 0.0055
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0029 0.002
Schistosoma mansoni neuropeptide receptor 0.0129 0.0568 0.1027
Brugia malayi hypothetical protein 0.0129 0.0568 0.056
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.0455 0.0495
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0129 0.0568 0.0619
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0568 0.1027
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0451 0.8837
Echinococcus granulosus Niemann Pick C1 protein 0.0468 0.2212 0.241
Schistosoma mansoni neuropeptide f receptor 76f 0.0129 0.0568 0.1027
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0533 0.2528 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0129 0.0568 0.1027
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0129 0.0568 0.0619
Schistosoma mansoni growth factor receptor-bound protein 0.0018 0.0029 0.0037
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0129 0.0568 0.056
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Schistosoma mansoni dynamin-associated protein 0.0018 0.0029 0.0037
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0018 0.0029 0.0032
Toxoplasma gondii AGC kinase 0.004 0.0133 0.5482
Brugia malayi RE15519p 0.0129 0.0568 0.056
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0111 0.012
Entamoeba histolytica hypothetical protein 0.0019 0.0031 0.0054
Loa Loa (eye worm) hypothetical protein 0.1136 0.5457 0.5947
Brugia malayi CXXC zinc finger family protein 0.0028 0.0077 0.0068
Toxoplasma gondii thioredoxin reductase 0.0046 0.0164 0.697
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.0032
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0184 0.0336
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0018 0.0032
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0009 0.001
Echinococcus multilocularis musashi 0.0026 0.0068 0.0074
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0228 0.0385
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0031 0.0034
Onchocerca volvulus 0.0232 0.1064 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0129 0.0568 0.0619
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0009 0.0009
Echinococcus multilocularis cpg binding protein 0.003 0.0084 0.0091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0568 0.1027
Echinococcus granulosus 7tm_1 domain containing protein 0.0129 0.0568 0.0619
Onchocerca volvulus 0.0129 0.0568 0.5335
Plasmodium vivax SET domain protein, putative 0.003 0.0085 0.4561
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.004 0.0133 0.0243
Echinococcus multilocularis Cbl interacting protein of 85 kDa 0.0018 0.0029 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.004 0.0133 0.5482
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0129 0.0568 0.1027
Schistosoma mansoni nebulin 0.0018 0.0029 0.0037
Schistosoma mansoni amine GPCR 0.0129 0.0568 0.1027
Loa Loa (eye worm) BAR domain-containing protein 0.0018 0.0029 0.0032
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0031 0.0034
Echinococcus granulosus allatostatin A receptor 0.0129 0.0568 0.0619
Echinococcus multilocularis neuropeptide receptor 0.0129 0.0568 0.0619
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0031 0.0034
Echinococcus granulosus neuropeptide FF receptor 2 0.0129 0.0568 0.0619
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0068 0.006
Schistosoma mansoni biogenic amine receptor 0.0129 0.0568 0.1027
Mycobacterium tuberculosis Probable reductase 0.0105 0.0451 0.8837
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0031 0.0034
Echinococcus granulosus sex peptide receptor 0.0129 0.0568 0.0619
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.1136 0.5457 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0203 0.8824
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0051 0.0055
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0031 0.0023
Echinococcus multilocularis sterol regulatory element binding protein 0.0468 0.2212 0.241
Schistosoma mansoni opsin-like receptor 0.0129 0.0568 0.1027
Brugia malayi MAP kinase sur-1 0.005 0.0184 0.0175
Echinococcus granulosus tm gpcr rhodopsin 0.0129 0.0568 0.0619
Echinococcus multilocularis fmrfamide receptor 0.0129 0.0568 0.0619
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0099 0.018
Loa Loa (eye worm) hypothetical protein 0.1903 0.9176 1
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.004 0.0133 0.0211
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0032
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.004 0.0133 0.0145
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0228 0.0417
Schistosoma mansoni hypothetical protein 0.0035 0.0111 0.0187
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.008 0.8073
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0031 0.0034
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.008 0.2928
Plasmodium falciparum glutathione reductase 0.0046 0.0164 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0133 0.0145
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0129 0.0568 0.056
Schistosoma mansoni amine GPCR 0.0129 0.0568 0.1027
Leishmania major protein kinase, putative 0.0013 0.0005 0.0008
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0729 0.3478 0.3791
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0029 0.002
Schistosoma mansoni opsin-like receptor 0.0129 0.0568 0.1027
Onchocerca volvulus 0.0018 0.0029 0.0269
Schistosoma mansoni cpg binding protein 0.003 0.0084 0.0139
Brugia malayi Cytochrome P450 family protein 0.0019 0.0032 0.0024
Onchocerca volvulus 0.0129 0.0568 0.5335
Leishmania major protein kinase, putative 0.0013 0.0005 0.0008
Leishmania major trypanothione reductase 0.0046 0.0164 0.03
Onchocerca volvulus 0.0129 0.0568 0.5335
Loa Loa (eye worm) abl-interactor 1 0.0018 0.0029 0.0032
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.008 0.4201
Trypanosoma brucei trypanothione reductase 0.0046 0.0164 0.0269
Brugia malayi hypothetical protein 0.0018 0.0029 0.002
Echinococcus granulosus Cbl interacting protein of 85 kDa 0.0018 0.0029 0.0031
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0451 0.8837
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0068 0.0074
Schistosoma mansoni single-minded 0.0047 0.0171 0.0297
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0022 0.0238
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0085 0.3179
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0028 0.0076 0.0082
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0018 0.007
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0051 0.0509
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0029 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.008 0.0313
Brugia malayi hypothetical protein 0.0159 0.0713 0.0704
Brugia malayi Serotonin receptor 0.0129 0.0568 0.056
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0184 0.02
Entamoeba histolytica hypothetical protein 0.0035 0.0111 0.1921
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Schistosoma mansoni amine GPCR 0.0129 0.0568 0.1027
Echinococcus granulosus pyruvate kinase 0.0017 0.0022 0.0023
Echinococcus granulosus G protein coupled receptor 139 0.0129 0.0568 0.0619
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0085 0.014
Onchocerca volvulus 0.0129 0.0568 0.5335
Schistosoma mansoni rotamase 0.0033 0.0099 0.0165
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0289 0.0314
Echinococcus granulosus protein of unknown function DUF2013 0.0018 0.0029 0.0031
Loa Loa (eye worm) hypothetical protein 0.003 0.0085 0.0093
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.0455 0.8918
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0129 0.0568 0.0619
Schistosoma mansoni cpg binding protein 0.003 0.0084 0.0139
Schistosoma mansoni hypothetical protein 0.0129 0.0568 0.1027
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0228 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0451 0.8837
Echinococcus granulosus pyruvate kinase 0.0032 0.0099 0.0107
Echinococcus multilocularis protein patched 0.0468 0.2212 0.241
Onchocerca volvulus 0.0129 0.0568 0.5335
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0455 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0184 0.0336
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0018 0.5
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0018 0.0029 0.0032
Echinococcus granulosus lamin 0.0026 0.0068 0.0074
Schistosoma mansoni amine GPCR 0.0129 0.0568 0.1027
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0031 0.0042
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0099 0.0388
Trypanosoma brucei pyruvate kinase 1, putative 0.0032 0.0099 0.0148
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0009 0.0009
Brugia malayi Death domain containing protein 0.0014 0.0009 0.000000009863
Brugia malayi hypothetical protein 0.0119 0.0516 0.0508
Onchocerca volvulus 0.0129 0.0568 0.5335
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0031 0.0034
Echinococcus granulosus tm gpcr rhodopsin 0.0129 0.0568 0.0619
Echinococcus granulosus Protein patched homolog 1 0.0468 0.2212 0.241
Schistosoma mansoni intermediate filament proteins 0.0026 0.0068 0.0109
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0228 0.0248
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.008 0.0245
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0026 0.0068 0.0074
Onchocerca volvulus 0.0129 0.0568 0.5335
Echinococcus granulosus protein kinase C and casein kinase substrate in 0.0018 0.0029 0.0031
Brugia malayi GnHR receptor homolog 0.0129 0.0568 0.056
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0129 0.0568 0.1027
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0164 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0034
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0451 0.8837
Echinococcus granulosus Src y 3 domain 0.0018 0.0029 0.0031
Schistosoma mansoni membrane traffic protein 0.0018 0.0029 0.0037
Onchocerca volvulus 0.0129 0.0568 0.5335
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0037
Brugia malayi Melatonin receptor type 1A 0.0129 0.0568 0.056
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0455 0.1797
Trypanosoma brucei paraflagellar rod protein 5, putative 0.0018 0.0029 0.002
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0031 0.0034
Brugia malayi putative neuropeptide receptor NPR1 0.0129 0.0568 0.056
Schistosoma mansoni adenoreceptor 0.0129 0.0568 0.1027
Trypanosoma brucei pyruvate kinase 1 0.0032 0.0099 0.0148
Trypanosoma brucei SH3 domain protein, conserved 0.0018 0.0029 0.002
Schistosoma mansoni neuropeptide receptor 0.0129 0.0568 0.1027
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.004 0.0133 0.0211
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0031 0.0034
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0032 0.0035
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.1136 0.5457 1
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0037
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus multilocularis lamin 0.0026 0.0068 0.0074
Plasmodium falciparum thioredoxin reductase 0.0046 0.0164 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0468 0.2212 0.241
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.004 0.0133 0.0145
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0032 0.0035
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Schistosoma mansoni sh3-containing grb2-like protein 3 (endophilin III) 0.0018 0.0029 0.0037
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0451 0.8837
Loa Loa (eye worm) AGC/PKA protein kinase 0.004 0.0133 0.0145
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.008 0.4201
Schistosoma mansoni tyrosine kinase 0.0738 0.3525 0.6455
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.1136 0.5457 0.5453
Echinococcus granulosus neuropeptides capa receptor 0.0129 0.0568 0.0619
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0002 0.0002
Echinococcus granulosus cpg binding protein 0.003 0.0084 0.0091
Toxoplasma gondii AGC kinase 0.004 0.0133 0.5482
Echinococcus multilocularis neuropeptide FF receptor 2 0.0129 0.0568 0.0619
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0036 0.005
Brugia malayi glutathione reductase 0.0046 0.0164 0.0156
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.0508 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0228 0.0385
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.0455 0.0495
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0129 0.0568 0.0619
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0031 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0122
Echinococcus multilocularis Ankyrin 0.0014 0.0009 0.001
Loa Loa (eye worm) G-protein coupled receptor 0.0129 0.0568 0.0619
Brugia malayi Dopamine receptor protein 1 0.0129 0.0568 0.056
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0031 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0568 0.1027
Echinococcus multilocularis G protein coupled receptor 139 0.0129 0.0568 0.0619
Giardia lamblia Kinase, AGC PKA 0.004 0.0133 0.0458
Leishmania major protein kinase A catalytic subunit isoform 2 0.004 0.0133 0.0243
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0129 0.0568 0.1027
Brugia malayi Dopamine receptor 0.0129 0.0568 0.056
Loa Loa (eye worm) hypothetical protein 0.0468 0.2212 0.241
Trypanosoma brucei protein kinase, putative 0.005 0.0184 0.0305
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0002 0.0002
Echinococcus multilocularis allatostatin A receptor 0.0129 0.0568 0.0619
Brugia malayi hypothetical protein 0.0129 0.0568 0.056
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0129 0.0568 0.0619
Echinococcus multilocularis pyruvate kinase 0.0017 0.0022 0.0023
Echinococcus multilocularis RIMS binding protein 2 0.0018 0.0029 0.0031
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0129 0.0568 0.1027
Echinococcus multilocularis pyruvate kinase 0.0032 0.0099 0.0107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0568 0.1027
Onchocerca volvulus 0.0129 0.0568 0.5335
Giardia lamblia Pyruvate kinase 0.0032 0.0099 0.032
Brugia malayi Thioredoxin reductase 0.0046 0.0164 0.0156
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus multilocularis pyruvate kinase 0.0017 0.0022 0.0023
Loa Loa (eye worm) TKL/MLK/MLK protein kinase 0.0019 0.0034 0.0037
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0455 0.1797
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.0653 0.0711
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0099 0.0921
Brugia malayi follicle stimulating hormone receptor 0.0129 0.0568 0.056
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0184 0.0725
Schistosoma mansoni tyrosine kinase 0.0028 0.0076 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0029 0.0052
Echinococcus granulosus g protein coupled receptor 0.0129 0.0568 0.0619
Echinococcus multilocularis g protein coupled receptor 0.0129 0.0568 0.0619
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0164 0.2985
Echinococcus multilocularis g protein coupled receptor 0.0129 0.0568 0.0619
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.004 0.0133 0.0243
Loa Loa (eye worm) TYRA-2 protein 0.0129 0.0568 0.0619
Echinococcus multilocularis somatostatin receptor 0.0129 0.0568 0.0619
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.1136 0.5457 0.5947
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0111 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0122
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0032 0.0026
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0099 0.0107
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0184 0.0336
Echinococcus granulosus expressed protein 0.0364 0.1706 0.1859
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0129 0.0568 0.0619
Brugia malayi hypothetical protein 0.0019 0.0031 0.0023
Loa Loa (eye worm) hypothetical protein 0.1893 0.9128 0.9949
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.004 0.0133 0.0145
Echinococcus multilocularis neuropeptides capa receptor 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0034
Echinococcus granulosus death domain containing protein 0.0014 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0122
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Schistosoma mansoni cpg binding protein 0.0028 0.0077 0.0124
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.008 0.2928
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0129 0.0568 0.1027
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0031 0.0042
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0175 0.0304
Echinococcus granulosus hypothetical protein 0.0129 0.0568 0.0619
Echinococcus granulosus intermediate filament protein 0.0026 0.0068 0.0074
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0122
Echinococcus granulosus neuropeptides capa receptor 0.0129 0.0568 0.0619
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0455 0.0496
Echinococcus multilocularis g-protein coupled receptor 0.0129 0.0568 0.0619
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0129 0.0568 0.1027
Schistosoma mansoni patched 1 0.0468 0.2212 0.4043
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0005 0.0008
Echinococcus granulosus g protein coupled receptor 0.0129 0.0568 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0099 0.0388
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0036 0.0038
Echinococcus granulosus biogenic amine 5HT receptor 0.0129 0.0568 0.0619
Echinococcus multilocularis microtubule associated protein 2 0.0672 0.3204 0.3491
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0029 0.002
Echinococcus multilocularis intersectin 2 0.0018 0.0029 0.0031
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0455 0.1797
Echinococcus multilocularis abl interactor 2 0.0018 0.0029 0.0031
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0184 0.0336
Brugia malayi Cytochrome P450 family protein 0.0048 0.0171 0.0163
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0129 0.0568 0.0619
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0031 0.0034
Echinococcus granulosus somatostatin receptor 0.0129 0.0568 0.0619
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.004 0.0133 0.7865
Schistosoma mansoni hypothetical protein 0.0129 0.0568 0.1027
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0031 0.0034
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0099 0.009
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0533 0.2528 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0129 0.0568 0.1027
Leishmania major hypothetical protein, conserved 0.0018 0.0029 0.0052
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.008 0.4201
Echinococcus granulosus pyruvate kinase 0.0017 0.0022 0.0023
Echinococcus granulosus tachykinin peptides receptor 99D 0.0129 0.0568 0.0619
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0099 0.018
Plasmodium falciparum pyruvate kinase 0.0032 0.0099 0.5493
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0184 0.02
Echinococcus multilocularis neuropeptide s receptor 0.0577 0.2744 0.299
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0129 0.0568 0.5335
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0036 0.0027
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0018 0.0032
Brugia malayi larval opioid receptor 0.0129 0.0568 0.056
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.0508 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0129 0.0568 0.0619
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0455 0.1797
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0077 0.0083
Echinococcus granulosus activated cdc42 kinase 1 0.1903 0.9176 1
Echinococcus multilocularis serotonin receptor 0.0129 0.0568 0.0619
Echinococcus granulosus dro:myosuppressin receptor 0.0129 0.0568 0.0619
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0164 0.0179
Loa Loa (eye worm) G-protein coupled receptor 0.0129 0.0568 0.0619
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0568 0.1027
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0029 0.002
Brugia malayi hypothetical protein 0.0129 0.0568 0.056
Onchocerca volvulus 0.0129 0.0568 0.5335
Echinococcus granulosus pyruvate kinase 0.0017 0.0022 0.0023
Echinococcus granulosus peptide allatostatin:somatostatin 0.0129 0.0568 0.0619
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0129 0.0568 0.1027
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0032
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0455 0.0803
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0034
Brugia malayi hypothetical protein 0.0129 0.0568 0.056
Schistosoma mansoni neuropeptide F-like receptor 0.0129 0.0568 0.1027
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0031 0.0034
Schistosoma mansoni hypothetical protein 0.0129 0.0568 0.1027
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0018 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0122
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0129 0.0568 0.0619
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0533 0.2528 1
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0099 0.0107
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.004 0.0133 0.0145
Echinococcus multilocularis Src y 3 domain 0.0018 0.0029 0.0031
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0039 0.0129 0.014
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Entamoeba histolytica hypothetical protein 0.0019 0.0031 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0133 0.0228
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0032
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0018 0.0019
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0129 0.0568 0.0619
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.0032
Leishmania major cytochrome p450-like protein 0.0019 0.0032 0.0058
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0005 0.0008
Echinococcus multilocularis activated cdc42 kinase 1 0.1903 0.9176 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0568 0.1027
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0018 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.001
Echinococcus granulosus tumor protein p63 0.0329 0.1539 0.1676
Echinococcus multilocularis protein of unknown function DUF2013 0.0018 0.0029 0.0031
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.1136 0.5457 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0018 0.0029 0.0031
Echinococcus multilocularis neuropeptides capa receptor 0.0129 0.0568 0.0619
Entamoeba histolytica hypothetical protein 0.0035 0.0111 0.1921
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.1136 0.5457 0.5947
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0029 0.002
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0012 0.0001 0.0001
Trichomonas vaginalis rotamase, putative 0.0032 0.0095 0.0374
Loa Loa (eye worm) hypothetical protein 0.0729 0.3478 0.3791
Loa Loa (eye worm) melatonin receptor type 1A 0.0129 0.0568 0.0619
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0095 0.0141
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0099 0.0921
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0009 0.001
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0129 0.0568 0.0619
Schistosoma mansoni pyruvate kinase 0.0032 0.0099 0.0165
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0095 0.0173
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.0455 0.0803
Echinococcus granulosus activated cdc42 kinase 1 0.1903 0.9176 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0031 0.0042
Plasmodium vivax glutathione reductase, putative 0.0046 0.0164 1
Echinococcus multilocularis neuropeptide Y receptor 0.0129 0.0568 0.0619
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0129 0.0568 0.0619
Echinococcus granulosus neuropeptide receptor 0.0129 0.0568 0.0619
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.008 0.2928
Brugia malayi PAS domain containing protein 0.0047 0.0171 0.0162
Echinococcus granulosus tyrosine protein kinase Src42A 0.0018 0.0029 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0568 0.1027
Echinococcus multilocularis sex peptide receptor 0.0129 0.0568 0.0619
Echinococcus granulosus g-protein coupled receptor 0.0129 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0159 0.0713 0.0777
Echinococcus granulosus 7TM GPCR rhodopsin 0.0129 0.0568 0.0619
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0031 0.0042
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0028 0.0076 0.0082
Loa Loa (eye worm) hypothetical protein 0.0129 0.0568 0.0619
Leishmania major protein kinase A catalytic subunit isoform 1 0.004 0.0133 0.0243

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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