Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | histone deacetylase, putative | 0.0214 | 0.551 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0109 | 0.1137 | 0.2063 |
Leishmania major | histone deacetylase, putative | 0.0214 | 0.551 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0321 | 1 | 1 |
Onchocerca volvulus | 0.0321 | 1 | 1 | |
Echinococcus multilocularis | histone deacetylase 7 | 0.0109 | 0.1137 | 0.1137 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 0.551 | 0.551 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0214 | 0.551 | 0.5 |
Echinococcus granulosus | histone deacetylase 6 | 0.0109 | 0.1137 | 0.1137 |
Echinococcus granulosus | histone deacetylase 7 | 0.0109 | 0.1137 | 0.1137 |
Giardia lamblia | Histone deacetylase | 0.0214 | 0.551 | 0.5 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0321 | 1 | 1 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0109 | 0.1137 | 0.1137 |
Trypanosoma brucei | histone deacetylase 4 | 0.0109 | 0.1137 | 0.2063 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0214 | 0.551 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0321 | 1 | 1 |
Echinococcus granulosus | peroxidasin | 0.0321 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0214 | 0.551 | 0.5 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0214 | 0.551 | 0.551 |
Plasmodium falciparum | histone deacetylase 1 | 0.0214 | 0.551 | 1 |
Trypanosoma brucei | histone deacetylase 1 | 0.0214 | 0.551 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0321 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0321 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0109 | 0.1137 | 0.1137 |
Brugia malayi | Animal haem peroxidase family protein | 0.0321 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0214 | 0.551 | 0.5 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0214 | 0.551 | 0.551 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0214 | 0.551 | 0.551 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0214 | 0.551 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0214 | 0.551 | 0.551 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0214 | 0.551 | 0.551 |
Entamoeba histolytica | histone deacetylase, putative | 0.0214 | 0.551 | 0.5 |
Echinococcus granulosus | histone deacetylase 3 | 0.0214 | 0.551 | 0.551 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0115 | 0.1386 | 0.1386 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0109 | 0.1137 | 0.2063 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0109 | 0.1137 | 0.1137 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0214 | 0.551 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0115 | 0.1386 | 0.1386 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0109 | 0.1137 | 0.2063 |
Onchocerca volvulus | Peroxidasin homolog | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase | 0.0109 | 0.1137 | 0.1137 |
Onchocerca volvulus | 0.0321 | 1 | 1 | |
Echinococcus granulosus | histone deacetylase 6 | 0.0115 | 0.1386 | 0.1386 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0109 | 0.1137 | 0.1137 |
Onchocerca volvulus | 0.0321 | 1 | 1 | |
Leishmania major | histone deacetylase, putative | 0.0214 | 0.551 | 1 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0214 | 0.551 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0321 | 1 | 1 |
Echinococcus granulosus | histone deacetylase | 0.0109 | 0.1137 | 0.1137 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0214 | 0.551 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0109 | 0.1137 | 0.2063 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0214 | 0.551 | 0.5 |
Brugia malayi | Peroxidasin | 0.0321 | 1 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.0321 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0214 | 0.551 | 0.5 |
Brugia malayi | Histone deacetylase 1 | 0.0214 | 0.551 | 0.551 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0109 | 0.1137 | 0.2063 |
Schistosoma mansoni | histone deacetylase | 0.0214 | 0.551 | 0.551 |
Trypanosoma brucei | histone deacetylase, putative | 0.0109 | 0.1137 | 0.2063 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0214 | 0.551 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0321 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0321 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0321 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0214 | 0.551 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0321 | 1 | 1 |
Plasmodium vivax | histone deacetylase, putative | 0.0109 | 0.1137 | 0.2063 |
Brugia malayi | Histone deacetylase family protein | 0.0109 | 0.1137 | 0.1137 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase | 0.0109 | 0.1137 | 0.1137 |
Echinococcus granulosus | histone deacetylase 1 | 0.0214 | 0.551 | 0.551 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0214 | 0.551 | 0.551 |
Brugia malayi | Blistered cuticle protein 3 | 0.0321 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0214 | 0.551 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0109 | 0.1137 | 0.1137 |
Trypanosoma brucei | histone deacetylase 3 | 0.0109 | 0.1137 | 0.2063 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0214 | 0.551 | 0.551 |
Schistosoma mansoni | peroxidasin | 0.0321 | 1 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0109 | 0.1137 | 0.1137 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0109 | 0.1137 | 0.1137 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.