Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0144 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0144 | 0 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0144 | 0 | 0.5 |
Brugia malayi | ecdysteroid receptor | 0.1283 | 0.4714 | 0.4714 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0144 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.256 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0144 | 0 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0144 | 0 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0144 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0144 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0144 | 0 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.1283 | 0.4714 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0144 | 0 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0144 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0144 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0144 | 0 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0144 | 0 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0144 | 0 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0144 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0144 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0144 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1283 | 0.4714 | 0.4714 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0144 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.249 | 0.971 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.