Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0059 | 0.0324 | 0.1087 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0103 | 0.1109 | 0.3728 |
Schistosoma mansoni | pol-related | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0059 | 0.0324 | 0.1087 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0103 | 0.1109 | 0.3728 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0205 | 0.2975 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0205 | 0.2975 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0205 | 0.2975 | 1 |
Giardia lamblia | Aldose reductase | 0.0205 | 0.2975 | 1 |
Brugia malayi | NADH-dependent xylose reductase | 0.0059 | 0.0324 | 0.1087 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0205 | 0.2975 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0205 | 0.2975 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0205 | 0.2975 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0103 | 0.1109 | 0.3728 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.055 | 0.9242 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0205 | 0.2975 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0205 | 0.2975 | 1 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0059 | 0.0324 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0103 | 0.1109 | 0.3728 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0103 | 0.1109 | 0.3728 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0205 | 0.2975 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0205 | 0.2975 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0103 | 0.1109 | 0.2963 |
Echinococcus multilocularis | aldo keto reductase | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0103 | 0.1109 | 0.2963 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0205 | 0.2975 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0205 | 0.2975 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0205 | 0.2975 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2975 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0205 | 0.2975 | 0.3219 |
Echinococcus granulosus | hypothetical protein | 0.0205 | 0.2975 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0205 | 0.2975 | 1 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0592 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0205 | 0.2975 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0205 | 0.2975 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0205 | 0.2975 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0205 | 0.2975 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0059 | 0.0324 | 0.035 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0103 | 0.1109 | 0.3728 |
Plasmodium vivax | aldehyde reductase, putative | 0.0059 | 0.0324 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0103 | 0.1109 | 0.3728 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0103 | 0.1109 | 0.3728 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0103 | 0.1109 | 0.2963 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0103 | 0.1109 | 0.3728 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0103 | 0.1109 | 0.3728 |
Onchocerca volvulus | 0.0205 | 0.2975 | 1 | |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0042 | 0 | 0.5 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0059 | 0.0324 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Onchocerca volvulus | 0.0205 | 0.2975 | 1 | |
Loa Loa (eye worm) | oxidoreductase | 0.0205 | 0.2975 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0205 | 0.2975 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0103 | 0.1109 | 0.3728 |
Echinococcus granulosus | aldehyde reductase | 0.0146 | 0.1894 | 0.6366 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0103 | 0.1109 | 0.2963 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0205 | 0.2975 | 1 |
Toxoplasma gondii | aldo-keto reductase | 0.0059 | 0.0324 | 0.1087 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0103 | 0.1109 | 0.3728 |
Onchocerca volvulus | 0.0205 | 0.2975 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0205 | 0.2975 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0205 | 0.2975 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0205 | 0.2975 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0205 | 0.2975 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0205 | 0.2975 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0205 | 0.2975 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0205 | 0.2975 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0205 | 0.2975 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0205 | 0.2975 | 1 |
Onchocerca volvulus | 0.0059 | 0.0324 | 0.1087 | |
Mycobacterium ulcerans | oxidoreductase | 0.0205 | 0.2975 | 0.2975 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0205 | 0.2975 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0205 | 0.2975 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0205 | 0.2975 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0103 | 0.1109 | 0.3728 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0205 | 0.2975 | 1 |
Onchocerca volvulus | 0.0205 | 0.2975 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0205 | 0.2975 | 1 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0059 | 0.0324 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0205 | 0.2975 | 1 |
Onchocerca volvulus | 0.0205 | 0.2975 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0146 | 0.1894 | 0.6366 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0205 | 0.2975 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0146 | 0.1894 | 0.6366 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0059 | 0.0324 | 0.1087 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0059 | 0.0324 | 0.1087 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0205 | 0.2975 | 1 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0059 | 0.0324 | 0.1087 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0205 | 0.2975 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0059 | 0.0324 | 0.1087 |
Entamoeba histolytica | aldose reductase, putative | 0.0205 | 0.2975 | 1 |
Onchocerca volvulus | 0.0205 | 0.2975 | 1 | |
Mycobacterium leprae | Possible oxidoreductase | 0.0059 | 0.0324 | 0.1087 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0205 | 0.2975 | 1 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0059 | 0.0324 | 0.1087 |
Giardia lamblia | Aldose reductase | 0.0205 | 0.2975 | 1 |
Schistosoma mansoni | potassium channel beta | 0.0059 | 0.0324 | 0.1087 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0205 | 0.2975 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0205 | 0.2975 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0205 | 0.2975 | 1 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0059 | 0.0324 | 0.1087 |
Mycobacterium ulcerans | hypothetical protein | 0.0059 | 0.0324 | 0.0324 |
Entamoeba histolytica | aldose reductase, putative | 0.0205 | 0.2975 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0103 | 0.1109 | 0.3728 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0059 | 0.0324 | 0.1087 |
Leishmania major | prostaglandin f synthase, putative | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0205 | 0.2975 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0205 | 0.2975 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0103 | 0.1109 | 0.2963 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0205 | 0.2975 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0205 | 0.2975 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0205 | 0.2975 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0103 | 0.1109 | 0.2963 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.