Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | NADH dehydrogenase I subunit F | 0.0177 | 0.5904 | 0.5 |
Brugia malayi | NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor | 0.0177 | 0.5904 | 0.4379 |
Trichomonas vaginalis | NADH-ubiquinone oxidoreductase flavoprotein, putative | 0.0177 | 0.5904 | 0.5 |
Leishmania major | NADH-ubiquinone oxidoreductase, mitochondrial, putative | 0.0177 | 0.5904 | 0.5 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase I (chain F) NuoF (NADH-ubiquinone oxidoreductase chain F) | 0.0177 | 0.5904 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.5533 | 0.8839 |
Wolbachia endosymbiont of Brugia malayi | NADH dehydrogenase I subunit F | 0.0177 | 0.5904 | 0.5 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0132 | 0.2712 | 0.5 |
Trypanosoma brucei | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, putative | 0.0177 | 0.5904 | 0.5 |
Echinococcus granulosus | NADH dehydrogenase ubiquinone flavoprotein 1 | 0.0177 | 0.5904 | 1 |
Echinococcus granulosus | geminin | 0.0172 | 0.5533 | 0.8839 |
Trypanosoma cruzi | NADH-ubiquinone oxidoreductase, mitochondrial, putative | 0.0177 | 0.5904 | 0.5 |
Trichomonas vaginalis | NADH-ubiquinone oxidoreductase flavoprotein, putative | 0.0177 | 0.5904 | 0.5 |
Schistosoma mansoni | NADH-ubiquinone oxidoreductase | 0.0177 | 0.5904 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.5533 | 0.8839 |
Echinococcus multilocularis | geminin | 0.0172 | 0.5533 | 0.8839 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0234 | 1 | 1 |
Loa Loa (eye worm) | NADH-ubiquinone oxidoreductase 51 kDa subunit | 0.0177 | 0.5904 | 0.4379 |
Trypanosoma cruzi | NADH-ubiquinone oxidoreductase, mitochondrial, putative | 0.0177 | 0.5904 | 0.5 |
Trypanosoma brucei | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | 0.0177 | 0.5904 | 0.5 |
Onchocerca volvulus | 0.0132 | 0.2712 | 1 | |
Echinococcus multilocularis | NADH dehydrogenase (ubiquinone) flavoprotein 1 | 0.0177 | 0.5904 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.