Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.1199 | 0.1728 |
Loa Loa (eye worm) | bromodomain containing protein | 0.002 | 0.1197 | 0.0967 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0 | 0.5 |
Schistosoma mansoni | zinc finger protein | 0.0018 | 0.0943 | 0.1338 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.2687 | 0.4001 |
Echinococcus multilocularis | zinc finger protein | 0.0025 | 0.1578 | 0.2597 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.2687 | 0.4001 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.215 | 0.1782 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0071 | 0.5883 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0042 | 0.3157 | 0.5313 |
Schistosoma mansoni | cpg binding protein | 0.0037 | 0.2764 | 0.4119 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.689 | 0.6809 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0 | 0.5 |
Echinococcus granulosus | cpg binding protein | 0.0037 | 0.2764 | 0.4637 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.2687 | 0.2495 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.1132 | 0.1625 |
Onchocerca volvulus | 0.0033 | 0.2383 | 0.5 | |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.002 | 0.1132 | 0.183 |
Trichomonas vaginalis | helicase, putative | 0.0008 | 0 | 0.5 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0255 | 0.0323 |
Schistosoma mansoni | bromodomain containing protein | 0.0075 | 0.6268 | 0.9469 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 1 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0 | 0.5 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0037 | 0.2687 | 0.4504 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.2383 | 0.3537 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0066 | 0.5394 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.3419 | 0.3247 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0116 | 1 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.1132 | 0.1625 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.4054 | 0.3898 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0024 | 0.1516 | 0.1294 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0079 | 0.6615 | 0.6456 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0 | 0.5 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.002 | 0.1132 | 0.183 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1199 | 0.0968 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0037 | 0.2687 | 0.2344 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0037 | 0.2687 | 0.4504 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.1199 | 0.1728 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.6615 | 0.6526 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0037 | 0.2687 | 0.2495 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0071 | 0.5838 | 0.8814 |
Schistosoma mansoni | cpg binding protein | 0.0037 | 0.2764 | 0.4119 |
Brugia malayi | Bromodomain containing protein | 0.0044 | 0.3411 | 0.3102 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.2687 | 0.4001 |
Trypanosoma cruzi | ISWI complex protein | 0.0018 | 0.0943 | 0.5 |
Echinococcus granulosus | zinc finger protein | 0.0025 | 0.1578 | 0.2597 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.3673 | 0.3507 |
Trypanosoma brucei | ISWI complex protein | 0.0018 | 0.0943 | 0.5 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.2383 | 0.2184 |
Echinococcus multilocularis | GPCR, family 2 | 0.0037 | 0.2687 | 0.4504 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0037 | 0.2687 | 0.4504 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0116 | 1 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0042 | 0.3157 | 0.5313 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.002 | 0.1199 | 0.1946 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.002 | 0.1199 | 0.1946 |
Echinococcus multilocularis | cpg binding protein | 0.0037 | 0.2764 | 0.4637 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.2383 | 0.2026 |
Schistosoma mansoni | zinc finger protein | 0.0025 | 0.1578 | 0.2307 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0037 | 0.2687 | 0.2344 |
Brugia malayi | Bromodomain containing protein | 0.0089 | 0.7525 | 0.7409 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0028 | 0.1896 | 0.3145 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0071 | 0.5883 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0037 | 0.2687 | 0.4504 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0255 | 0.0323 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0028 | 0.1896 | 0.3145 |
Echinococcus granulosus | GPCR family 2 | 0.0037 | 0.2687 | 0.4504 |
Trypanosoma cruzi | ISWI complex protein | 0.0018 | 0.0943 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0028 | 0.1896 | 0.2793 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0943 | 0.1338 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0018 | 0.0943 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.6615 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.2687 | 0.4001 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.1516 | 0.2212 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.