Detailed information for compound 881263

Basic information

Technical information
  • TDR Targets ID: 881263
  • Name: N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)- 4-(trifluoromethoxy)benzenesulfonamide
  • MW: 378.39 | Formula: C14H13F3N2O3S2
  • H donors: 1 H acceptors: 3 LogP: 4.07 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: FC(Oc1ccc(cc1)S(=O)(=O)Nc1nc2c(s1)CCCC2)(F)F
  • InChi: 1S/C14H13F3N2O3S2/c15-14(16,17)22-9-5-7-10(8-6-9)24(20,21)19-13-18-11-3-1-2-4-12(11)23-13/h5-8H,1-4H2,(H,18,19)
  • InChiKey: YCJKKUWETIWHEA-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0057 0.0066
Entamoeba histolytica hypothetical protein 0.0036 0.089 0.089
Echinococcus granulosus cathepsin L 0.0009 0.0005 0.0005
Plasmodium vivax vivapain-1 0.0009 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0325 0.0375
Brugia malayi EGF-like domain containing protein 0.0087 0.2598 0.2997
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Mycobacterium tuberculosis Conserved protein 0.0047 0.127 0.2683
Echinococcus granulosus protein jagged 2 0.0087 0.2598 0.2997
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0146 0.0169
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Mycobacterium tuberculosis Conserved protein 0.0047 0.127 0.2683
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Brugia malayi Papain family cysteine protease containing protein 0.0009 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Mycobacterium ulcerans glyoxalase GloA 0.0047 0.127 0.2683
Echinococcus granulosus neurogenic locus notch protein 4 0.0087 0.2598 0.2997
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0536 0.0619
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0363 0.0363
Echinococcus granulosus neurogenic locus protein delta 0.0087 0.2598 0.2997
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0146 0.0226
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Plasmodium vivax vivapain-3 0.0009 0.0005 0.0007
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0363 0.0561
Onchocerca volvulus Putative protein 0.0047 0.127 0.1465
Brugia malayi Cathepsin L-like precursor 0.0018 0.0291 0.0335
Echinococcus multilocularis cysteine protease 0.0018 0.0291 0.0335
Loa Loa (eye worm) hypothetical protein 0.0012 0.0088 0.0102
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Echinococcus granulosus neurogenic locus notch protein 0.0087 0.2598 0.2997
Brugia malayi lactoylglutathione lyase 0.0203 0.648 0.7476
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.089 0.1027
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0057 0.0066
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0363 0.0419
Schistosoma mansoni glucose transport protein 0.0059 0.1658 0.1912
Leishmania major cathepsin L-like protease 0.0018 0.0291 0.0449
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1949 1
Brugia malayi EGF-like domain containing protein 0.0087 0.2598 0.2997
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0057 0.0066
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0536 0.1133
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0291 0.0335
Toxoplasma gondii glyoxalase I, putative 0.0203 0.648 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0536 0.0536
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0057 0.0066
Brugia malayi Papain family cysteine protease containing protein 0.0009 0.0005 0.0005
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0536 0.0619
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0057 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.0005 0.0005
Onchocerca volvulus 0.0018 0.0291 0.0335
Loa Loa (eye worm) hypothetical protein 0.0203 0.648 0.7476
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0057 0.0066
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0057 0.0066
Schistosoma mansoni glucose transport protein 0.0059 0.1658 0.1912
Echinococcus multilocularis fat cadherin tumor suppressor 0.0087 0.2598 0.2997
Echinococcus granulosus neural cadherin 0.0087 0.2598 0.2997
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0057 0.0066
Loa Loa (eye worm) ctsf protein 0.0018 0.0291 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0146 0.0146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1949 1
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Entamoeba histolytica cysteine proteinase, putative 0.0009 0.0005 0.0005
Onchocerca volvulus Dual oxidase homolog 0.0269 0.8668 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1949 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1949 1
Brugia malayi Carboxylesterase family protein 0.0012 0.0088 0.0102
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.1995 0.2302
Entamoeba histolytica hypothetical protein 0.0036 0.089 0.089
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0291 0.0335
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0291 0.0615
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0146 0.0146
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.1213 0.14
Brugia malayi Calcium binding EGF domain containing protein 0.0087 0.2598 0.2997
Echinococcus granulosus fibropellin Ia 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0019 0.0325 0.0375
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0291 0.0291
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0146 0.0146
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0203 0.648 1
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0066
Echinococcus granulosus cathepsin l1 0.0012 0.0096 0.011
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0146 0.0146
Brugia malayi hypothetical protein 0.0269 0.8668 1
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.089 0.1027
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0536 0.0536
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.0047 0.127 0.1465
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.0047 0.127 0.2683
Schistosoma mansoni notch 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Leishmania major cathepsin L-like protease 0.0018 0.0291 0.0449
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.0047 0.127 0.2683
Onchocerca volvulus Peroxidase homolog 0.0269 0.8668 1
Echinococcus multilocularis neurogenic locus notch protein 0.0087 0.2598 0.2997
Leishmania major protein kinase, putative 0.0013 0.0146 0.0226
Schistosoma mansoni ap endonuclease 0.002 0.0363 0.0419
Leishmania major cathepsin L-like protease 0.0067 0.1949 0.3007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0066
Brugia malayi Cathepsin L-like precursor 0.0012 0.0096 0.011
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0363 0.0419
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0066
Onchocerca volvulus 0.0018 0.0291 0.0335
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0087 0.2598 0.2997
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0291 0.0615
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0087 0.2598 0.2997
Echinococcus multilocularis fibropellin Ia 0.0087 0.2598 0.2997
Schistosoma mansoni glucose transport protein 0.0059 0.1658 0.1912
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0291 0.0291
Brugia malayi notch-like transmembrane receptor 0.0087 0.2598 0.2997
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.1213 0.14
Brugia malayi hypothetical protein 0.0036 0.089 0.1027
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.127 0.2683
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0057 0.0066
Brugia malayi Animal haem peroxidase family protein 0.0269 0.8668 1
Brugia malayi Cathepsin L-like precursor 0.0018 0.0291 0.0335
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0363 0.0768
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Onchocerca volvulus Peroxidasin homolog 0.0269 0.8668 1
Echinococcus granulosus BC026374 protein S09 family 0.0012 0.0088 0.0102
Loa Loa (eye worm) hypothetical protein 0.0019 0.0325 0.0375
Onchocerca volvulus 0.0013 0.0146 0.0169
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Onchocerca volvulus Chorion peroxidase homolog 0.0269 0.8668 1
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Trypanosoma cruzi cysteine proteinase, putative 0.0009 0.0005 0.0007
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0536 0.1133
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0088 0.0102
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Trypanosoma cruzi cysteine peptidase, putative 0.0009 0.0005 0.0007
Plasmodium vivax glyoxalase I, putative 0.0203 0.648 1
Brugia malayi PAS domain containing protein 0.0051 0.1415 0.1632
Brugia malayi cathepsin L-like precursor 0.0012 0.0096 0.011
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0291 0.0335
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0363 0.0363
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.0047 0.127 0.1465
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0291 0.0291
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0059 0.1658 0.1912
Brugia malayi Calcium binding EGF domain containing protein 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.011
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.1949 0.3007
Schistosoma mansoni coup transcription factor 0.0011 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0025 0.0536 0.0619
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0059 0.1658 0.1912
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0291 0.0449
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0.0005 0.0005
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0146 0.0169
Echinococcus multilocularis para nitrobenzyl esterase 0.0012 0.0088 0.0102
Mycobacterium ulcerans carboxylesterase, LipT 0.0012 0.0088 0.0187
Onchocerca volvulus 0.0269 0.8668 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1949 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0057 0.0066
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0057 0.0066
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0057 0.0066
Echinococcus granulosus neurogenic locus notch protein 0.0087 0.2598 0.2997
Echinococcus granulosus peroxidasin 0.0269 0.8668 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.1213 0.14
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0057 0.0066
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0291 0.0335
Loa Loa (eye worm) carboxylesterase 0.0012 0.0088 0.0102
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0012 0.0088 0.0187
Loa Loa (eye worm) Notch2 0.0087 0.2598 0.2997
Echinococcus granulosus delta-like protein 1 0.0087 0.2598 0.2997
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0012 0.0088 0.0102
Brugia malayi hypothetical protein 0.0012 0.0088 0.0102
Trypanosoma cruzi cruzipain precursor, putative 0.0067 0.1949 0.3007
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0057 0.0066
Schistosoma mansoni ap endonuclease 0.002 0.0363 0.0419
Brugia malayi hypoxia-induced factor 1 0.0159 0.5006 0.5776
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0536 0.1133
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0057 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0057 0.0066
Schistosoma mansoni acetylcholinesterase 0.0012 0.0088 0.0102
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0363 0.0363
Brugia malayi Carboxylesterase family protein 0.0069 0.1995 0.2302
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0057 0.0066
Schistosoma mansoni BC026374 protein (S09 family) 0.0012 0.0088 0.0102
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.1213 0.14
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0363 0.0419
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0291 0.0335
Echinococcus granulosus protein jagged 2 0.0087 0.2598 0.2997
Plasmodium falciparum cysteine proteinase falcipain 1 0.0009 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0536 0.1133
Schistosoma mansoni hypothetical protein 0.0087 0.2598 0.2997
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0291 0.0335
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0536 0.0827
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Brugia malayi Animal haem peroxidase family protein 0.0269 0.8668 1
Brugia malayi Blistered cuticle protein 3 0.0269 0.8668 1
Mycobacterium ulcerans hypothetical protein 0.0047 0.127 0.2683
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0291 0.0449
Echinococcus multilocularis carboxylesterase 5A 0.0069 0.1995 0.2302
Brugia malayi MH2 domain containing protein 0.0118 0.3649 0.4209
Echinococcus granulosus notch 0.0087 0.2598 0.2997
Brugia malayi Carboxylesterase family protein 0.0012 0.0088 0.0102
Onchocerca volvulus 0.0012 0.0088 0.0102
Brugia malayi EGF-like domain containing protein 0.0087 0.2598 0.2997
Brugia malayi Carboxylesterase family protein 0.0069 0.1995 0.2302
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.1949 0.3007
Echinococcus multilocularis neurogenic locus protein delta 0.0087 0.2598 0.2997
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.127 0.127
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0059 0.1658 0.1912
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0363 0.0561
Echinococcus granulosus cathepsin l1 0.0018 0.0291 0.0335
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0363 0.0561
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1949 1
Echinococcus granulosus cysteine protease 0.0009 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0146 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.127 0.127
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0291 0.0449
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0969 0.1118
Brugia malayi EGF-like domain containing protein 0.0087 0.2598 0.2997
Onchocerca volvulus 0.0012 0.0088 0.0102
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0536 0.1133
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0146 0.0226
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Schistosoma mansoni septate junction protein 0.0087 0.2598 0.2997
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0325 0.0687
Loa Loa (eye worm) carboxylesterase 0.0069 0.1995 0.2302
Onchocerca volvulus 0.0012 0.0088 0.0102
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0012 0.0088 0.0187
Echinococcus multilocularis neural cadherin 0.0087 0.2598 0.2997
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0012 0.0088 0.0102
Entamoeba histolytica cysteine protease, putative 0.0018 0.0291 0.0291
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.1213 0.14
Onchocerca volvulus 0.0087 0.2598 0.2997
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0069 0.1995 0.2302
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.1213 0.14
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0146 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0096 0.0096
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0146 0.0226
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0291 0.0335
Brugia malayi Animal haem peroxidase family protein 0.0269 0.8668 1
Onchocerca volvulus 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Mycobacterium ulcerans hypothetical protein 0.0047 0.127 0.2683
Leishmania major cathepsin L-like protease 0.0018 0.0291 0.0449
Treponema pallidum fructose-bisphosphate aldolase 0.0309 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0057 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0057 0.0066
Trypanosoma cruzi cysteine protease, putative 0.0009 0.0005 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0057 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0536 0.0619
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Echinococcus multilocularis BC026374 protein (S09 family) 0.0012 0.0088 0.0102
Brugia malayi Animal haem peroxidase family protein 0.0269 0.8668 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0291 0.0291
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0291 0.0335
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0203 0.648 0.7476
Onchocerca volvulus 0.0018 0.0291 0.0335
Entamoeba histolytica cysteine proteinase 2 0.0009 0.0005 0.0005
Onchocerca volvulus 0.0018 0.0291 0.0335
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0536 0.1133
Onchocerca volvulus Neurogenic locus notch homolog 0.0087 0.2598 0.2997
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0057 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0057 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0203 0.648 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0146 0.0226
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0291 0.0291
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0057 0.0066
Plasmodium vivax glyoxalase I, putative 0.0047 0.127 0.1959
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.0012 0.0088 0.0102
Onchocerca volvulus 0.0269 0.8668 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0291 0.0291
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0012 0.0088 0.0102
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0057 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0057 0.0066
Trichomonas vaginalis spcc417.12 protein, putative 0.0012 0.0088 0.0088
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0203 0.648 1
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0057 0.0066
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0057 0.0066
Entamoeba histolytica cysteine proteinase, putative 0.0009 0.0005 0.0005
Brugia malayi GCC2 and GCC3 family protein 0.0087 0.2598 0.2997
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Leishmania major cathepsin L-like protease 0.0067 0.1949 0.3007
Onchocerca volvulus Slit protein homolog 0.0087 0.2598 0.2997
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.0047 0.127 0.1465
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Brugia malayi nuclear hormone receptor 0.0011 0.0057 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0096 0.0096
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0363 0.5
Echinococcus granulosus cathepsin L cysteine protease 0.0009 0.0005 0.0005
Plasmodium falciparum glyoxalase I 0.0047 0.127 0.1959
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Leishmania major cathepsin L-like protease 0.0067 0.1949 0.3007
Onchocerca volvulus 0.0018 0.0291 0.0335
Brugia malayi nuclear receptor NHR-88 0.0011 0.0057 0.0066
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0291 0.0449
Loa Loa (eye worm) animal heme peroxidase 0.0269 0.8668 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0363 0.1865
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0291 0.0615
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0363 0.0363
Brugia malayi Cathepsin L-like precursor 0.0012 0.0096 0.011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0291 0.0615
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0057 0.0066
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0291 0.0335
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Schistosoma mansoni laminin gamma-3 chain 0.0087 0.2598 0.2997
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0057 0.0066
Plasmodium vivax hexose transporter 0.0059 0.1658 0.2558
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0.0005 0.0005
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0173 0.5452 0.629
Schistosoma mansoni gynecophoral canal protein 0.0047 0.127 0.1465
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Mycobacterium tuberculosis Carboxylesterase LipT 0.0012 0.0088 0.0187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1949 1
Brugia malayi Cadherin domain containing protein 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0066
Onchocerca volvulus 0.0012 0.0088 0.0102
Onchocerca volvulus 0.0087 0.2598 0.2997
Loa Loa (eye worm) cysteine protease 0.0018 0.0291 0.0335
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0146 0.0226
Onchocerca volvulus 0.0269 0.8668 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Brugia malayi Sugar transporter family protein 0.0059 0.1658 0.1912
Mycobacterium ulcerans hypothetical protein 0.0047 0.127 0.2683
Brugia malayi Muscle positioning protein 4 0.0087 0.2598 0.2997
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.3649 0.4209
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0057 0.0066
Entamoeba histolytica cysteine proteinase 1, putative 0.0009 0.0005 0.0005
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0146 0.0146
Loa Loa (eye worm) notch protein 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0069 0.1995 0.2302
Onchocerca volvulus Peroxidase homolog 0.0269 0.8668 1
Plasmodium vivax unspecified product 0.0009 0.0005 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.1213 0.14
Toxoplasma gondii cathepsin CPL 0.0018 0.0291 0.0449
Echinococcus multilocularis slit 2 protein 0.0087 0.2598 0.2997
Echinococcus multilocularis cysteine protease 0.0018 0.0291 0.0335
Toxoplasma gondii exonuclease III APE 0.002 0.0363 0.0561
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0325 0.0687
Toxoplasma gondii glyoxalase family protein 0.0047 0.127 0.1959
Onchocerca volvulus 0.0018 0.0291 0.0335
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0057 0.0066
Onchocerca volvulus 0.0011 0.0057 0.0066
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0057 0.0066
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0969 0.1118
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.1213 0.14
Mycobacterium ulcerans hypothetical protein 0.0025 0.0536 0.1133
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Entamoeba histolytica cysteine proteinase, putative 0.0009 0.0005 0.0005
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.1468 0.2265
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0009 0.0005 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.1658 0.1658
Plasmodium falciparum glyoxalase I 0.0203 0.648 1
Echinococcus granulosus carboxylesterase 5A 0.0069 0.1995 0.2302
Echinococcus granulosus protein jagged 1 0.0087 0.2598 0.2997
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0057 0.0066
Schistosoma mansoni neuroligin 3 (S09 family) 0.0012 0.0088 0.0102
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0057 0.0066
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0536 0.0536
Schistosoma mansoni hypothetical protein 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0291 0.0449
Brugia malayi Cathepsin L-like precursor 0.0018 0.0291 0.0335
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0057 0.0066
Leishmania major cathepsin L-like protease 0.0018 0.0291 0.0449
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0151 0.4732 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0536 0.1133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1949 1
Echinococcus multilocularis neuroligin 0.0012 0.0088 0.0102
Onchocerca volvulus 0.0025 0.0536 0.0619
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0059 0.1658 0.1912
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.011
Echinococcus multilocularis cathepsin L 0.0009 0.0005 0.0005
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0363 0.0561
Mycobacterium tuberculosis Conserved protein TB27.3 0.0047 0.127 0.2683
Plasmodium vivax vivapain-2 0.0018 0.0291 0.0449
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0291 0.0291
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0018 0.0291 0.0335
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0057 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0066
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0057 0.0066
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0146 0.0169
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0363 0.0561
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.3649 0.4209
Loa Loa (eye worm) sugar transporter 0.0059 0.1658 0.1912
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Brugia malayi ecdysteroid receptor 0.0011 0.0057 0.0066
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0012 0.0088 0.0088
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0059 0.1658 0.1912
Toxoplasma gondii EGF family domain-containing protein 0.0087 0.2598 0.4009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0146 0.0146
Leishmania major protein kinase, putative 0.0013 0.0146 0.0226
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0066
Brugia malayi Carboxylesterase family protein 0.0012 0.0088 0.0102
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0291 0.0291
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0057 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0291 0.0291
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Schistosoma mansoni notch 0.0087 0.2598 0.2997
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0291 0.0335
Loa Loa (eye worm) animal heme peroxidase 0.0269 0.8668 1
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0291 0.0335
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.0005 0.0005
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0151 0.4732 1
Brugia malayi Cathepsin L-like precursor 0.0018 0.0291 0.0335
Loa Loa (eye worm) animal heme peroxidase 0.0269 0.8668 1
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0291 0.0335
Mycobacterium ulcerans hypothetical protein 0.0047 0.127 0.2683
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0536 0.0827
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Schistosoma mansoni hypothetical protein 0.0087 0.2598 0.2997
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0012 0.0088 0.0102
Brugia malayi Animal haem peroxidase family protein 0.0269 0.8668 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.0005 0.0024
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0325 1
Mycobacterium ulcerans hypothetical protein 0.0047 0.127 0.2683
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 1 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Schistosoma mansoni hypothetical protein 0.0059 0.1658 0.1912
Mycobacterium ulcerans glyoxalase GloA 0.0047 0.127 0.2683
Loa Loa (eye worm) hypothetical protein 0.0019 0.0325 0.0375
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0057 0.0066
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0291 0.0335
Brugia malayi EGF-like domain containing protein 0.0087 0.2598 0.2997
Mycobacterium ulcerans hypothetical protein 0.0047 0.127 0.2683
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0536 0.1133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1949 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0363 0.0768
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0536 0.1133
Echinococcus granulosus acetylcholinesterase 0.0069 0.1995 0.2302
Schistosoma mansoni peroxidasin 0.0269 0.8668 1
Onchocerca volvulus 0.0012 0.0096 0.011
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0057 0.0066
Giardia lamblia High cysteine protein 0.0087 0.2598 0.2598
Echinococcus multilocularis acetylcholinesterase 0.0069 0.1995 0.2302
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.1213 0.14
Plasmodium vivax vivapain-2 0.0018 0.0291 0.0449
Echinococcus granulosus para nitrobenzyl esterase 0.0012 0.0088 0.0102
Loa Loa (eye worm) hypothetical protein 0.0012 0.0088 0.0102
Entamoeba histolytica hypothetical protein 0.0036 0.089 0.089
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.1415 0.1632
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Schistosoma mansoni hypothetical protein 0.0087 0.2598 0.2997
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Echinococcus granulosus protein jagged 1 0.0087 0.2598 0.2997
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0096 0.011
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Entamoeba histolytica cysteine proteinase, putative 0.0009 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Echinococcus multilocularis neurogenic locus protein delta 0.0087 0.2598 0.2997
Brugia malayi hypothetical protein 0.0173 0.5452 0.629
Brugia malayi EGF-like domain containing protein 0.0087 0.2598 0.2997
Schistosoma mansoni hypothetical protein 0.0036 0.089 0.1027
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0057 0.0066
Mycobacterium leprae Possible regulatory protein 0.0013 0.0146 0.0309
Echinococcus multilocularis General substrate transporter 0.0053 0.1465 0.169
Echinococcus granulosus acetylcholinesterase 0.0069 0.1995 0.2302
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.011
Loa Loa (eye worm) carboxylesterase 0.0012 0.0088 0.0102
Loa Loa (eye worm) acetylcholinesterase 1 0.0069 0.1995 0.2302
Giardia lamblia Fructose-bisphosphate aldolase 0.0309 1 1
Onchocerca volvulus 0.0018 0.0291 0.0335
Loa Loa (eye worm) hypothetical protein 0.0012 0.0088 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Schistosoma mansoni notch 0.0087 0.2598 0.2997
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0057 0.0066
Echinococcus multilocularis acetylcholinesterase 0.0069 0.1995 0.2302
Loa Loa (eye worm) hypothetical protein 0.0025 0.0536 0.0619
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1949 1
Schistosoma mansoni cell polarity protein 0.0087 0.2598 0.2997
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Loa Loa (eye worm) blistered cuticle protein 3 0.0269 0.8668 1
Onchocerca volvulus Peroxidasin homolog 0.0269 0.8668 1
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.1949 0.3007
Schistosoma mansoni slit 0.0087 0.2598 0.2997
Echinococcus multilocularis neurogenic locus notch protein 0.0087 0.2598 0.2997
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0088 0.0102
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Echinococcus multilocularis notch 0.0087 0.2598 0.2997
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0057 0.0066
Brugia malayi Peroxidasin 0.0269 0.8668 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0088 0.0102
Echinococcus multilocularis neurogenic locus notch protein 4 0.0087 0.2598 0.2997
Schistosoma mansoni gliotactin 0.0012 0.0088 0.0102
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0146 0.0146
Echinococcus multilocularis protein jagged 1 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypoxia-induced factor 1 0.0159 0.5006 0.5776
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0325 0.0501
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0057 0.0066
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0536 0.0827
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0057 0.0066
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0291 0.0291
Schistosoma mansoni hypothetical protein 0.0087 0.2598 0.2997
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.1754 0.2706
Onchocerca volvulus 0.0087 0.2598 0.2997
Echinococcus multilocularis protein jagged 2 0.0087 0.2598 0.2997
Schistosoma mansoni notch 0.0087 0.2598 0.2997
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0057 0.0066
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0536 0.1133
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0146 0.0169
Schistosoma mansoni single-minded 0.0051 0.1415 0.1632
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0057 0.0066
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0059 0.1658 0.1912
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0363 0.0419
Schistosoma mansoni notch 0.0087 0.2598 0.2997
Mycobacterium leprae conserved hypothetical protein 0.0047 0.127 0.2683
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0146 0.0226
Loa Loa (eye worm) hypothetical protein 0.0013 0.0146 0.0169
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.089 0.1027
Brugia malayi EGF-like domain containing protein 0.0087 0.2598 0.2997
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0151 0.4732 1
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Brugia malayi Calcium binding EGF domain containing protein 0.0087 0.2598 0.2997
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0969 0.2049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0057 0.0066
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Echinococcus granulosus single minded 2 0.0038 0.0969 0.1118
Brugia malayi Carboxylesterase family protein 0.0012 0.0088 0.0102
Brugia malayi Cathepsin L-like precursor 0.0018 0.0291 0.0335
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0325 0.0501
Loa Loa (eye worm) hypothetical protein 0.0019 0.0325 0.0375
Leishmania major cathepsin L-like protease 0.0018 0.0291 0.0449
Echinococcus granulosus slit 2 protein 0.0087 0.2598 0.2997
Entamoeba histolytica cysteine protease, putative 0.0009 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0087 0.2598 0.2997
Loa Loa (eye worm) hypothetical protein 0.0269 0.8668 1
Onchocerca volvulus 0.0038 0.0969 0.1118
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0096 0.011
Toxoplasma gondii facilitative glucose transporter GT1 0.0059 0.1658 0.2558
Echinococcus granulosus General substrate transporter 0.0053 0.1465 0.169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.0005 0.0024
Echinococcus multilocularis peroxidasin 0.0269 0.8668 1
Loa Loa (eye worm) fibroinase 0.0018 0.0291 0.0335
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1949 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0057 0.0066
Brugia malayi Cadherin domain containing protein 0.0087 0.2598 0.2997
Brugia malayi steroid hormone receptor 0.0011 0.0057 0.0066
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0291 0.0335
Trypanosoma cruzi cysteine proteinase, putative 0.0009 0.0005 0.0007
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0059 0.1658 0.1912
Onchocerca volvulus 0.0087 0.2598 0.2997
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0057 0.0066
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0087 0.2598 0.2997
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0291 0.0291
Brugia malayi Delta serrate ligand family protein 0.0087 0.2598 0.2997
Loa Loa (eye worm) animal heme peroxidase 0.0269 0.8668 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0536 0.0619
Echinococcus multilocularis protein jagged 1 0.0087 0.2598 0.2997
Plasmodium falciparum hexose transporter 0.0059 0.1658 0.2558
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0146 0.0226
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Entamoeba histolytica hypothetical protein 0.0036 0.089 0.089
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0536 0.1133
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0088 0.0102
Schistosoma mansoni notch 0.0087 0.2598 0.2997
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0146 0.0169
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0059 0.1658 0.1912
Schistosoma mansoni peroxidasin 0.0269 0.8668 1
Schistosoma mansoni hypothetical protein 0.0087 0.2598 0.2997
Onchocerca volvulus 0.0012 0.0088 0.0102
Onchocerca volvulus Putative cubilin 0.0087 0.2598 0.2997
Brugia malayi Cathepsin L-like precursor 0.0018 0.0291 0.0335
Echinococcus granulosus neuroligin 0.0012 0.0088 0.0102

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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