Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0036 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0036 | 1 | 0.5 |
Onchocerca volvulus | 0.0036 | 1 | 0.5 | |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0036 | 1 | 0.5 |
Onchocerca volvulus | 0.0036 | 1 | 0.5 | |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0036 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0036 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0036 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0036 | 1 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0036 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Onchocerca volvulus | 0.0036 | 1 | 0.5 | |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0036 | 1 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0036 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0036 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0036 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0036 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0036 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0036 | 1 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0036 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0036 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0036 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0036 | 1 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0036 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0036 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0036 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0036 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0036 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0036 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Onchocerca volvulus | 0.0036 | 1 | 0.5 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0036 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0036 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0036 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0036 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0036 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Onchocerca volvulus | 0.0036 | 1 | 0.5 | |
Loa Loa (eye worm) | oxidoreductase | 0.0036 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0036 | 1 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0036 | 1 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0036 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0036 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0036 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0036 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0036 | 1 | 1 |
Schistosoma mansoni | pol-related | 0.0036 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0036 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0036 | 1 | 1 |
Onchocerca volvulus | 0.0036 | 1 | 0.5 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0036 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0036 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0036 | 1 | 0.5 |
Trypanosoma brucei | prostaglandin f synthase | 0.0036 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0036 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0036 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0036 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0036 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0036 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0036 | 1 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0036 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0036 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0036 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0036 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0036 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0036 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0036 | 1 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0036 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0036 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0036 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0036 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.