TDR Targets

Basic information

Technical information

TDR Targets ID: 882718
Name: methyl 4-[6,7-dimethyl-2-(5-methyl-1,2-oxazol -3-yl)-3,9-dioxo-1H-chromeno[3,2-c]pyrrol-1-y l]benzoate
MW: 444.436 | Formula: C25H20N2O6
H donors: 0 H acceptors: 4 LogP: 3.81 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: COC(=O)c1ccc(cc1)C1N(c2noc(c2)C)C(=O)c2c1c(=O)c1c(o2)cc(c(c1)C)C
InChi: 1S/C25H20N2O6/c1-12-9-17-18(10-13(12)2)32-23-20(22(17)28)21(15-5-7-16(8-6-15)25(30)31-4)27(24(23)29)19-11-14(3)33-26-19/h5-11,21H,1-4H3
InChiKey: NBCPGNBTODCLNS-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

methyl 4-[6,7-dimethyl-2-(5-methylisoxazol-3-yl)-3,9-dioxo-1H-chromeno[3,2-c]pyrrol-1-yl]benzoate
4-[6,7-dimethyl-2-(5-methyl-3-isoxazolyl)-3,9-dioxo-1H-chromeno[3,2-c]pyrrol-1-yl]benzoic acid methyl ester
4-[3,9-diketo-6,7-dimethyl-2-(5-methylisoxazol-3-yl)-1H-chromeno[3,2-c]pyrrol-1-yl]benzoic acid methyl ester
STOCK5S-79638

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma cruzi	cysteine peptidase, putative	0.0158	0.3145	0.2733
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.011	0.21	0.5255
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0473	1	1
Onchocerca volvulus		0.004	0.0566	0.0837
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0088	0.1612	0.3583
Echinococcus granulosus	cathepsin L cysteine protease	0.0088	0.1612	0.1612
Echinococcus multilocularis	cathepsin L	0.0088	0.1612	0.1612
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0473	1	1
Onchocerca volvulus		0.0158	0.3145	1
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0158	0.3145	1
Brugia malayi	cathepsin F-like cysteine proteinase	0.004	0.0566	0.0534
Plasmodium vivax	vivapain-2	0.0158	0.3145	1
Echinococcus granulosus	cathepsin l1	0.0158	0.3145	0.3145
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0473	1	1
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0174	0.3484	0.3093
Brugia malayi	cathepsin L-like cysteine proteinase	0.004	0.0566	0.0534
Trypanosoma cruzi	cysteine proteinase, putative	0.0088	0.1612	0.1108
Schistosoma mansoni	cathepsin s	0.0048	0.0737	0.0419
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Brugia malayi	Cathepsin L-like precursor	0.0158	0.3145	0.3122
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0088	0.1612	0.1108
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.004	0.0566	0.0566
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0319	0.0319
Loa Loa (eye worm)	ctsf protein	0.0158	0.3145	0.3145
Echinococcus granulosus	cysteine protease	0.0088	0.1612	0.1612
Entamoeba histolytica	cysteine proteinase, putative	0.011	0.21	0.5946
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0174	0.3484	0.3261
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Onchocerca volvulus	Cathepsin L homolog	0.0158	0.3145	1
Onchocerca volvulus	Cathepsin L homolog	0.004	0.0566	0.0837
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.0016	0.0034	0.0034
Echinococcus granulosus	lamin dm0	0.0029	0.0331	0.0331
Brugia malayi	Papain family cysteine protease containing protein	0.004	0.0566	0.0534
Loa Loa (eye worm)	intermediate filament protein	0.0029	0.0331	0.0331
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Entamoeba histolytica	cysteine proteinase 1, putative	0.0088	0.1612	0.4054
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.004	0.0566	0.0243
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.004	0.0566	0.0534
Brugia malayi	Cathepsin L-like cysteine proteinase	0.011	0.21	0.2073
Giardia lamblia	Cathepsin B precursor	0.0174	0.3484	1
Brugia malayi	Papain family cysteine protease containing protein	0.004	0.0566	0.0534
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0158	0.3145	0.8838
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Echinococcus multilocularis	cathepsin b	0.0473	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0158	0.3145	0.8838
Brugia malayi	cathepsin L-like precursor	0.011	0.21	0.2073
Loa Loa (eye worm)	hypothetical protein	0.004	0.0566	0.0566
Brugia malayi	Cathepsin L-like precursor	0.0158	0.3145	0.3122
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0158	0.3145	0.8189
Entamoeba histolytica	cysteine proteinase, putative	0.0088	0.1612	0.4054
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0158	0.3145	0.8838
Loa Loa (eye worm)	hypothetical protein	0.004	0.0566	0.0566
Brugia malayi	Intermediate filament tail domain containing protein	0.0029	0.0331	0.0298
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0158	0.3145	0.8189
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0088	0.1612	0.1325
Echinococcus multilocularis	musashi	0.0029	0.0331	0.0331
Brugia malayi	Cathepsin L-like precursor	0.0158	0.3145	0.3122
Brugia malayi	cathepsin L precursor	0.004	0.0566	0.0534
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0737	0.0737
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0088	0.1612	0.1325
Loa Loa (eye worm)	fibroinase	0.0158	0.3145	0.3145
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0158	0.3145	0.8189
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0737	0.0737
Giardia lamblia	Cathepsin B precursor	0.0174	0.3484	1
Brugia malayi	Papain family cysteine protease containing protein	0.004	0.0566	0.0534
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.004	0.0566	0.0566
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.011	0.21	0.1625
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0158	0.3145	0.8189
Echinococcus granulosus	cathepsin l1	0.011	0.21	0.21
Plasmodium vivax	vivapain-2	0.0158	0.3145	1
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0158	0.3145	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Brugia malayi	Cathepsin L-like precursor	0.011	0.21	0.2073
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0158	0.3145	0.8838
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.004	0.0566	0.0243
Brugia malayi	Papain family cysteine protease containing protein	0.0088	0.1612	0.1583
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0737	0.0737
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0158	0.3145	0.8838
Echinococcus multilocularis	cysteine protease	0.0158	0.3145	0.3145
Echinococcus granulosus	lamin	0.0029	0.0331	0.0331
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0473	1	1
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0174	0.3484	1
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.004	0.0566	0.0243
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0331	0.0331
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Loa Loa (eye worm)	hypothetical protein	0.0473	1	1
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.004	0.0566	0.0566
Echinococcus multilocularis	lamin dm0	0.0029	0.0331	0.0331
Onchocerca volvulus		0.011	0.21	0.6285
Loa Loa (eye worm)	hypothetical protein	0.004	0.0566	0.0566
Giardia lamblia	Cathepsin B precursor	0.0174	0.3484	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0158	0.3145	0.8189
Onchocerca volvulus		0.0158	0.3145	1
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0158	0.3145	0.3145
Brugia malayi	Papain family cysteine protease containing protein	0.0088	0.1612	0.1583
Loa Loa (eye worm)	hypothetical protein	0.011	0.21	0.21
Brugia malayi	cathepsin Z-like cysteine proteinase	0.004	0.0566	0.0534
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0088	0.1612	0.1325
Plasmodium vivax	vivapain-1	0.0088	0.1612	0.4054
Trypanosoma cruzi	cysteine peptidase, putative	0.0158	0.3145	0.2733
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0048	0.0737	0.0737
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0158	0.3145	0.3145
Loa Loa (eye worm)	hypothetical protein	0.0158	0.3145	0.3145
Schistosoma mansoni	cathepsin B (C01 family)	0.004	0.0566	0.0243
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0158	0.3145	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.004	0.0566	0.0243
Echinococcus granulosus	cathepsin b	0.0473	1	1
Echinococcus multilocularis	lamin	0.0029	0.0331	0.0331
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0088	0.1612	0.4054
Trypanosoma cruzi	cysteine peptidase, putative	0.0158	0.3145	0.2733
Plasmodium vivax	unspecified product	0.0088	0.1612	0.4054
Brugia malayi	Cathepsin L-like precursor	0.011	0.21	0.2073
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0158	0.3145	0.8189
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.011	0.21	0.5255
Entamoeba histolytica	cysteine proteinase, putative	0.0088	0.1612	0.4054
Trypanosoma cruzi	cruzipain precursor, putative	0.0048	0.0737	0.018
Trypanosoma cruzi	cysteine protease, putative	0.0088	0.1612	0.1108
Schistosoma mansoni	cathepsin F (C01 family)	0.0158	0.3145	0.291
Echinococcus multilocularis	cathepsin L cysteine protease	0.0158	0.3145	0.3145
Echinococcus granulosus	cathepsin L	0.004	0.0566	0.0566
Brugia malayi	intermediate filament protein	0.0029	0.0331	0.0298
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0158	0.3145	0.8189
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0029	0.0331	0.0331
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0174	0.3484	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0158	0.3145	0.8189
Onchocerca volvulus	Cathepsin L homolog	0.0158	0.3145	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.004	0.0566	0.0243
Brugia malayi	Cathepsin L-like precursor	0.0158	0.3145	0.3122
Brugia malayi	Cathepsin L-like precursor	0.0158	0.3145	0.3122
Echinococcus multilocularis	cathepsin L	0.004	0.0566	0.0566
Plasmodium vivax	vivapain-3	0.0088	0.1612	0.4054
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.004	0.0566	0.0243
Brugia malayi	Cathepsin L-like precursor	0.0048	0.0737	0.0705
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0158	0.3145	0.3145
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Schistosoma mansoni	cathepsin F (C01 family)	0.011	0.21	0.1829
Toxoplasma gondii	cathepsin B	0.0174	0.3484	1
Echinococcus granulosus	intermediate filament protein	0.0029	0.0331	0.0331
Brugia malayi	cathepsin F-like cysteine proteinase	0.0048	0.0737	0.0705
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Entamoeba histolytica	cysteine proteinase 2	0.0088	0.1612	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Entamoeba histolytica	cysteine proteinase, putative	0.0158	0.3145	1
Onchocerca volvulus		0.0158	0.3145	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0473	1	1
Entamoeba histolytica	cysteine proteinase, putative	0.0088	0.1612	0.4054
Toxoplasma gondii	cathepsin CPL	0.0158	0.3145	0.8838
Entamoeba histolytica	cysteine protease, putative	0.0158	0.3145	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0158	0.3145	0.8838
Loa Loa (eye worm)	hypothetical protein	0.011	0.21	0.21
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0158	0.3145	0.3145
Onchocerca volvulus	Cathepsin F homolog	0.0158	0.3145	1
Plasmodium vivax	unspecified product	0.0048	0.0737	0.066
Echinococcus granulosus	cathepsin b	0.0473	1	1
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.004	0.0566	0.0243
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Schistosoma mansoni	cathepsin S (C01 family)	0.004	0.0566	0.0243
Echinococcus multilocularis	cathepsin b	0.0473	1	1
Schistosoma mansoni	cathepsin C	0.004	0.0566	0.0243
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0158	0.3145	0.3145
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.004	0.0566	0.0243
Onchocerca volvulus		0.0158	0.3145	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0088	0.1612	0.3583
Loa Loa (eye worm)	cysteine protease	0.0158	0.3145	0.3145
Loa Loa (eye worm)	hypothetical protein	0.004	0.0566	0.0566
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Entamoeba histolytica	cysteine proteinase, putative	0.0158	0.3145	1
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Loa Loa (eye worm)	cathepsin B	0.0174	0.3484	0.3484
Loa Loa (eye worm)	hypothetical protein	0.004	0.0566	0.0566
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Brugia malayi	Papain family cysteine protease containing protein	0.0158	0.3145	0.3122
Trypanosoma cruzi	cysteine peptidase, putative	0.0048	0.0737	0.018
Onchocerca volvulus		0.0158	0.3145	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0158	0.3145	0.8838
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0158	0.3145	0.3145
Onchocerca volvulus		0.0158	0.3145	1
Loa Loa (eye worm)	hypothetical protein	0.004	0.0566	0.0566
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0158	0.3145	0.8838
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.0048	0.0737	0.0705
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Echinococcus multilocularis	cysteine protease	0.0158	0.3145	0.3145
Schistosoma mansoni	cathepsin F (C01 family)	0.0158	0.3145	0.291
Brugia malayi	Cathepsin L-like precursor	0.0158	0.3145	0.3122
Trypanosoma cruzi	cysteine peptidase, putative	0.0088	0.1612	0.1108
Trypanosoma cruzi	cysteine proteinase, putative	0.0088	0.1612	0.1108
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0158	0.3145	0.8838
Trypanosoma cruzi	cysteine peptidase, putative	0.0158	0.3145	0.2733
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0158	0.3145	0.8189
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0158	0.3145	0.8838
Entamoeba histolytica	cysteine proteinase, putative	0.0088	0.1612	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0158	0.3145	0.8189
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.004	0.0566	0.0243
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0158	0.3145	0.8838
Trypanosoma cruzi	cruzipain precursor, putative	0.0158	0.3145	0.2733
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0158	0.3145	0.8838
Onchocerca volvulus		0.0158	0.3145	1
Brugia malayi	cathepsin Z-like cysteine proteinase	0.004	0.0566	0.0534
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0158	0.3145	0.8189
Entamoeba histolytica	cysteine protease, putative	0.0088	0.1612	0.4054
Loa Loa (eye worm)	hypothetical protein	0.011	0.21	0.21
Echinococcus multilocularis	cathepsin L cysteine protease	0.0158	0.3145	0.3145
Echinococcus granulosus	cathepsin L	0.0088	0.1612	0.1612
Brugia malayi	fibroinase precursor	0.004	0.0566	0.0534
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0174	0.3484	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 882718