Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 1 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0021 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 1 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0021 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 1 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 1 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 1 | 0.5 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0021 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 1 | 0.5 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0021 | 1 | 0.5 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 1 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 1 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0021 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 1 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0021 | 1 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 1 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0021 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 1 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 1 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0021 | 1 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 1 | 0.5 |
Trypanosoma brucei | unspecified product | 0.0021 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 1 | 0.5 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0021 | 1 | 0.5 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0021 | 1 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0021 | 1 | 0.5 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0021 | 1 | 0.5 |
Echinococcus granulosus | dna polymerase eta | 0.0021 | 1 | 0.5 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0021 | 1 | 0.5 |
Echinococcus granulosus | dna polymerase kappa | 0.0021 | 1 | 0.5 |
Schistosoma mansoni | DNA polymerase eta | 0.0021 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.