Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | protein kinase c epsilon type | 0.0333 | 0.5623 | 0.5202 |
Loa Loa (eye worm) | hypothetical protein | 0.029 | 0.432 | 0.0031 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0405 | 0.7792 | 0.758 |
Echinococcus granulosus | protein kinase c iota type | 0.0176 | 0.0877 | 0.0877 |
Brugia malayi | Protein kinase c protein 2 | 0.0377 | 0.6944 | 1 |
Onchocerca volvulus | 0.029 | 0.432 | 0.5 | |
Echinococcus granulosus | RNA directed DNA polymerase | 0.029 | 0.431 | 0.431 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0333 | 0.5623 | 0.419 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0147 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0478 | 1 | 1 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0304 | 0.4736 | 0.1361 |
Echinococcus granulosus | protein kinase C gamma type | 0.0405 | 0.7792 | 0.7792 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0333 | 0.5623 | 0.5623 |
Loa Loa (eye worm) | hypothetical protein | 0.0393 | 0.7443 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.6528 | 0.7079 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0248 | 0.3056 | 0.2388 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.029 | 0.431 | 0.3763 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0333 | 0.5623 | 0.5202 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.029 | 0.431 | 0.3763 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0478 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.029 | 0.432 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.029 | 0.432 | 0.0031 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0478 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0362 | 0.6518 | 0.7049 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.