Detailed information for compound 883210

Basic information

Technical information
  • TDR Targets ID: 883210
  • Name: methyl 3-[(2,4-difluorophenyl)sulfonylamino]- 4-methylbenzoate
  • MW: 341.33 | Formula: C15H13F2NO4S
  • H donors: 1 H acceptors: 3 LogP: 2.86 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccc(c(c1)NS(=O)(=O)c1ccc(cc1F)F)C
  • InChi: 1S/C15H13F2NO4S/c1-9-3-4-10(15(19)22-2)7-13(9)18-23(20,21)14-6-5-11(16)8-12(14)17/h3-8,18H,1-2H3
  • InChiKey: LPRRTNOIYGGNIO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • methyl 3-[(2,4-difluorophenyl)sulfonylamino]-4-methyl-benzoate
  • 3-[(2,4-difluorophenyl)sulfonylamino]-4-methylbenzoic acid methyl ester
  • 3-[(2,4-difluorophenyl)sulfonylamino]-4-methyl-benzoic acid methyl ester
  • T5341233
  • ZINC03432502

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus integrin alpha ps 0.014 0.0148 0.0148
Brugia malayi Protein kinase domain containing protein 0.0032 0.0012 0.0012
Schistosoma mansoni dock 0.0035 0.0017 0.0016
Plasmodium vivax plasmepsin V, putative 0.0254 0.0291 0.4596
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Schistosoma mansoni hypothetical protein 0.0046 0.003 0.0029
Loa Loa (eye worm) TK/ALK protein kinase 0.0046 0.003 0.0029
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0057 0.0044 0.0043
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0251 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0237 0.0269 0.0269
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.004 0.0022 0.0513
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.3094 0.3857 0.3857
Plasmodium vivax LCCL domain-containing protein 0.0035 0.0017 0.0254
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0049 0.0034 0.0034
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0049 0.0034 0.0042
Plasmodium falciparum plasmepsin V 0.0254 0.0291 0.4596
Mycobacterium ulcerans Type I modular polyketide synthase 0.0027 0.0006 0.0129
Echinococcus multilocularis SWI:SNF complex subunit SMARCC2 0.0041 0.0024 0.0029
Schistosoma mansoni amine oxidase 0.0099 0.0097 0.0096
Loa Loa (eye worm) glutamate receptor 1 0.0033 0.0013 0.0013
Echinococcus granulosus glutamate receptor subunit protein glur 0.0033 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0034 0.0015 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0099 0.0097 0.1521
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0488 0.0585 0.0732
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0034 0.0014 0.0014
Toxoplasma gondii subtilisin SUB10 0.0365 0.043 0.6791
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0034 0.0054
Brugia malayi hypothetical protein 0.0299 0.0347 0.0347
Giardia lamblia High cysteine membrane protein Group 2 0.2931 0.3653 1
Brugia malayi Glutamate receptor 2 precursor 0.0033 0.0013 0.0013
Toxoplasma gondii aspartyl protease ASP5 0.0232 0.0263 0.4148
Echinococcus granulosus discoidin domain containing receptor 2 0.0035 0.0017 0.0016
Mycobacterium tuberculosis Possible oxidoreductase 0.0099 0.0097 0.225
Schistosoma mansoni glutamate receptor NMDA 0.0049 0.0034 0.0034
Brugia malayi angiogenesis inhibito 0.0133 0.014 0.0139
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0099 0.0097 0.225
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Loa Loa (eye worm) glutamate receptor 2 0.0033 0.0013 0.0013
Echinococcus granulosus glutamate receptor 2 0.0049 0.0034 0.0034
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0028 0.0008 0.0178
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Brugia malayi EGF-like domain containing protein 0.0089 0.0085 0.0084
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0227 0.0258 0.0257
Brugia malayi metalloprotease 0.0063 0.0051 0.0051
Schistosoma mansoni discoidin domain receptor 0.0035 0.0017 0.0016
Echinococcus granulosus fibrillin 1 0.0092 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.1595 0.1976 0.1976
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0049 0.0034 0.048
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Onchocerca volvulus 0.0032 0.0012 0.0182
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0084 0.0077 0.1794
Leishmania major subtilisin-like serine peptidase 0.0365 0.043 1
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0228 0.0259 0.0258
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0365 0.043 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.003 0.0029
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0365 0.043 0.0537
Trichomonas vaginalis hypothetical protein 0.1595 0.1976 0.3231
Schistosoma mansoni protein kinase 0.0123 0.0127 0.0126
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0331 0.0388 0.8377
Loa Loa (eye worm) hypothetical protein 0.0133 0.014 0.0139
Schistosoma mansoni SWI/SNF complex-related 0.0041 0.0024 0.0024
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0007 0.0006
Brugia malayi Subtilase family protein 0.0365 0.043 0.043
Brugia malayi Disintegrin family protein 0.0095 0.0091 0.009
Echinococcus multilocularis integrin alpha ps 0.014 0.0148 0.0185
Echinococcus granulosus lysine specific histone demethylase 1A 0.0099 0.0097 0.0096
Trypanosoma brucei subtilisin peptidase 0.0365 0.043 0.9378
Schistosoma mansoni glutamate receptor AMPA 0.0033 0.0013 0.0013
Leishmania major UDP-galactopyranose mutase 0.0099 0.0097 0.2025
Echinococcus multilocularis tissue type plasminogen activator 0.0032 0.0012 0.0015
Toxoplasma gondii subtilisin SUB12 0.0365 0.043 0.6791
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0028 0.0008 0.0178
Toxoplasma gondii subtilisin SUB1 0.0526 0.0633 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.4891 0.6115 1
Echinococcus multilocularis nuclear receptor 2C2 associated protein 0.0035 0.0017 0.002
Loa Loa (eye worm) transcriptional regulator 0.0049 0.0034 0.0033
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0034 0.0015 0.0014
Brugia malayi NAD-dependent deacetylase SIRT1 0.0049 0.0034 0.0033
Trichomonas vaginalis WD repeat domain, putative 0.0134 0.0141 0.0229
Schistosoma mansoni site-1 peptidase (S08 family) 0.0365 0.043 0.043
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0016
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0049 0.0034 0.0779
Loa Loa (eye worm) hypothetical protein 0.0041 0.0024 0.0024
Echinococcus granulosus discoidin domain containing receptor 2 0.0035 0.0017 0.0016
Echinococcus multilocularis discoidin domain containing receptor 2 0.0035 0.0017 0.002
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0365 0.043 0.043
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0025 0.0003 0.0078
Brugia malayi Kringle domain containing protein 0.0032 0.0012 0.0012
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0034 0.0015 0.0014
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0033 0.0013 0.0016
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0034 0.0054
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0123 0.0127 0.0126
Loa Loa (eye worm) hypothetical protein 0.0057 0.0044 0.0043
Echinococcus granulosus SWI:SNF complex subunit SMARCC2 0.0041 0.0024 0.0024
Plasmodium vivax subtilisin-like protease 2, putative 0.0365 0.043 0.6791
Echinococcus multilocularis fibrillin 2 0.0089 0.0085 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.1595 0.1976 0.3231
Trichomonas vaginalis conserved hypothetical protein 0.1595 0.1976 0.3231
Giardia lamblia Tenascin-X 0.0089 0.0085 0.0167
Echinococcus multilocularis fibrillin 1 0.0105 0.0104 0.0129
Schistosoma mansoni integrin alpha-ps 0.0073 0.0064 0.0063
Toxoplasma gondii hypothetical protein 0.0089 0.0085 0.1327
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.1595 0.1976 0.3231
Loa Loa (eye worm) endoprotease bli-4 0.7984 1 1
Schistosoma mansoni hypothetical protein 0.0134 0.0141 0.014
Loa Loa (eye worm) TK/EGFR protein kinase 0.054 0.0651 0.065
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0049 0.0034 0.0042
Loa Loa (eye worm) hypothetical protein 0.0228 0.0259 0.0258
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0667 0.081 0.081
Echinococcus granulosus epidermal growth factor receptor 0.054 0.0651 0.065
Schistosoma mansoni glutamate receptor kainate 0.0033 0.0013 0.0013
Echinococcus multilocularis integrin alpha ps 0.0067 0.0057 0.007
Mycobacterium leprae Possible secreted protease 0.0365 0.043 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Trypanosoma cruzi subtilisin peptidase 0.0365 0.043 0.9408
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0035 0.0017 0.0026
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0027 0.0006 0.0129
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0331 0.0388 0.8455
Schistosoma mansoni tyrosine kinase 0.054 0.0651 0.065
Schistosoma mansoni glutamate receptor kainate 0.0033 0.0013 0.0013
Giardia lamblia Tenascin-37 0.0089 0.0085 0.0167
Echinococcus granulosus tissue type plasminogen activator 0.0032 0.0012 0.0012
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0488 0.0585 0.0585
Echinococcus multilocularis integrin alpha ps 0.014 0.0148 0.0185
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0228 0.0259 0.0258
Brugia malayi neuroendocrine convertase 1 precursor 0.5054 0.6319 0.6319
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0049 0.0034 0.0042
Schistosoma mansoni hypothetical protein 0.0057 0.0044 0.0043
Plasmodium vivax subtilisin-like serine protease, putative 0.0365 0.043 0.6791
Chlamydia trachomatis protoporphyrinogen oxidase 0.0099 0.0097 1
Mycobacterium leprae Polyketide synthase Pks13 0.004 0.0022 0.0513
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0025 0.0003 0.0003
Echinococcus multilocularis protein jagged 2 0.0089 0.0085 0.0105
Echinococcus granulosus glutamate NMDA receptor subunit 0.0275 0.0318 0.0317
Schistosoma mansoni chromatin regulatory protein sir2 0.0331 0.0388 0.0387
Echinococcus multilocularis disintegrin and metalloproteinase 0.0095 0.0091 0.0113
Loa Loa (eye worm) hypothetical protein 0.0646 0.0784 0.0783
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.1595 0.1976 0.3231
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Schistosoma mansoni ADAMTS14 peptidase (M12 family) 0.0063 0.0051 0.0051
Onchocerca volvulus 0.0025 0.0003 0.0044
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0365 0.043 1
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Loa Loa (eye worm) hypothetical protein 0.0046 0.003 0.0029
Schistosoma mansoni dihydroceramide desaturase 0.0095 0.0091 0.009
Brugia malayi ADAMTS-like protease 0.0133 0.014 0.0139
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0049 0.0034 0.0026
Loa Loa (eye worm) hypothetical protein 0.0488 0.0585 0.0585
Giardia lamblia hypothetical protein 0.0089 0.0085 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Toxoplasma gondii subtilisin SUB4 0.0365 0.043 0.6791
Trichomonas vaginalis conserved hypothetical protein 0.0365 0.043 0.0703
Toxoplasma gondii kringle domain-containing protein 0.0032 0.0012 0.0184
Echinococcus multilocularis chromatin regulatory protein sir2 0.0331 0.0388 0.0484
Mycobacterium ulcerans oxidoreductase 0.0099 0.0097 0.225
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.196 0.2434 0.398
Echinococcus multilocularis 0.0099 0.0097 0.012
Giardia lamblia Neurogenic locus Notch protein precursor 0.0089 0.0085 0.0167
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0365 0.043 1
Echinococcus granulosus Coagulation factor 5 8 type C terminal 0.0035 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0016
Plasmodium falciparum subtilisin-like protease 1 0.0526 0.0633 1
Echinococcus multilocularis integrin beta 2 0.3103 0.387 0.4839
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0099 0.0097 0.1521
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0035 0.0017 0.0026
Brugia malayi Will die slowly protein 0.0134 0.0141 0.014
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0365 0.043 1
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0027 0.0006 0.0129
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Onchocerca volvulus 0.0134 0.0141 0.2204
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0049 0.0034 0.0041
Schistosoma mansoni hypothetical protein 0.0067 0.0057 0.0056
Brugia malayi transcriptional regulator, Sir2 family protein 0.0331 0.0388 0.0387
Echinococcus granulosus c-Jun N-terminal kinases 0.0251 0.0287 0.0287
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0099 0.0097 0.225
Schistosoma mansoni chromatin regulatory protein sir2 0.0049 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.007 0.0061 0.006
Trichomonas vaginalis conserved hypothetical protein 0.1595 0.1976 0.3231
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0049 0.0034 0.0041
Toxoplasma gondii F5/8 type C domain-containing protein 0.0035 0.0017 0.0254
Brugia malayi proprotein convertase 2 0.5054 0.6319 0.6319
Schistosoma mansoni chromatin regulatory protein sir2 0.0049 0.0034 0.0033
Schistosoma mansoni chromatin regulatory protein sir2 0.0049 0.0034 0.0033
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0365 0.043 0.9408
Toxoplasma gondii SWIRM domain-containing protein 0.0041 0.0024 0.0372
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0028 0.0008 0.0178
Trichomonas vaginalis beta-hexosaminidase B, putative 0.0035 0.0017 0.0026
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0049 0.0034 0.0034
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0084 0.0077 0.5
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0049 0.0034 0.0033
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0116 0.0118 0.0147
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0331 0.0388 0.0387
Loa Loa (eye worm) hypothetical protein 0.0089 0.0085 0.0084
Mycobacterium tuberculosis Possible arabinofuranosyltransferase AftD 0.0035 0.0017 0.0386
Brugia malayi Protein kinase domain containing protein 0.0046 0.003 0.0029
Brugia malayi hypothetical protein 0.0046 0.003 0.0029
Loa Loa (eye worm) metalloprotease 0.0063 0.0051 0.0051
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0049 0.0034 0.0041
Loa Loa (eye worm) hypothetical protein 0.0046 0.003 0.0029
Schistosoma mansoni site-1 peptidase (S08 family) 0.0365 0.043 0.043
Onchocerca volvulus 0.0035 0.0017 0.0252
Toxoplasma gondii subtilisin SUB8 0.0365 0.043 0.6791
Mycobacterium ulcerans polyketide synthase Pks13 0.004 0.0022 0.0513
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0049 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0365 0.043 0.0703
Loa Loa (eye worm) hypothetical protein 0.0141 0.0149 0.0148
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.196 0.2434 0.398
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0089 0.0085 0.0137
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0331 0.0388 0.0484
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0331 0.0388 1
Echinococcus multilocularis glutamate receptor 2 0.0033 0.0013 0.0016
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0331 0.0388 0.0633
Schistosoma mansoni chromatin regulatory protein sir2 0.0331 0.0388 0.0387
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.196 0.2434 0.398
Echinococcus multilocularis discoidin domain containing receptor 2 0.0035 0.0017 0.002
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0049 0.0034 0.051
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0095 0.0091 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0024 0.0038
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0049 0.0034 0.0521
Brugia malayi Stress-activated protein kinase jnk-1 0.0251 0.0287 0.0287
Loa Loa (eye worm) reprolysin 0.0228 0.0259 0.0258
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0099 0.0097 0.1521
Schistosoma mansoni hypothetical protein 0.0057 0.0044 0.0043
Echinococcus multilocularis protein will die slowly 0.0134 0.0141 0.0175
Toxoplasma gondii F5/8 type C domain-containing protein 0.0035 0.0017 0.0254
Echinococcus granulosus serine:threonine protein kinase N2 0.007 0.006 0.0059
Brugia malayi Calcium binding EGF domain containing protein 0.003 0.001 0.0009
Echinococcus multilocularis protein kinase c epsilon type 0.0085 0.008 0.0099
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0034 0.0054
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0095 0.0091 0.009
Brugia malayi Protein kinase domain containing protein 0.0035 0.0017 0.0016
Echinococcus multilocularis discoidin domain containing receptor 2 0.0035 0.0017 0.002
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0099 0.0097 0.1521
Loa Loa (eye worm) hypothetical protein 0.0049 0.0034 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Onchocerca volvulus 0.0046 0.003 0.0467
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0033 0.0013 0.0016
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0057 0.0044 0.0054
Schistosoma mansoni integrin alpha-ps 0.014 0.0148 0.0148
Plasmodium vivax hypothetical protein, conserved 0.0099 0.0097 0.1521
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Loa Loa (eye worm) transcriptional regulator 0.0331 0.0388 0.0387
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0228 0.0259 0.0323
Toxoplasma gondii PA14 domain-containing protein 0.0035 0.0017 0.0254
Loa Loa (eye worm) hypothetical protein 0.0089 0.0085 0.0084
Brugia malayi Glutamate receptor 1 precursor 0.0033 0.0013 0.0013
Brugia malayi Kelch motif family protein 0.0667 0.081 0.081
Trichomonas vaginalis conserved hypothetical protein 0.1595 0.1976 0.3231
Echinococcus granulosus MAM 0.0046 0.003 0.0029
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0365 0.043 1
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0386 0.0456 1
Trichomonas vaginalis conserved hypothetical protein 0.1595 0.1976 0.3231
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Echinococcus granulosus membrane bound transcription factor site 1 0.0365 0.043 0.043
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0107 0.0107 0.0107
Toxoplasma gondii subtilisin SUB5 0.0365 0.043 0.6791
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0084 0.0077 0.5
Schistosoma mansoni glutamate receptor AMPA 0.0033 0.0013 0.0013
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Brugia malayi protein kinase C II. 0.0085 0.008 0.0079
Giardia lamblia Neurogenic locus notch-like protein 0.0089 0.0085 0.0167
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0099 0.0097 0.225
Schistosoma mansoni hypothetical protein 0.0046 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0045 0.0028 0.0028
Plasmodium vivax LCCL domain-containing protein 0.0035 0.0017 0.0254
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0057 0.0044 0.0043
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0713 0.0868 0.0867
Plasmodium falciparum protoporphyrinogen oxidase 0.0099 0.0097 0.1521
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Schistosoma mansoni furin-1 (S08 family) 0.3458 0.4315 0.4315
Echinococcus multilocularis neuroendocrine convertase 2 0.5054 0.6319 0.7903
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0365 0.043 0.043
Plasmodium falciparum LCCL domain-containing protein 0.0035 0.0017 0.0254
Schistosoma mansoni integrin alpha 0.0313 0.0365 0.0365
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0386 0.0456 1
Brugia malayi ADAM-TS Spacer 1 family protein 0.0133 0.014 0.0139
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0085 0.008 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.1595 0.1976 0.3231
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0099 0.0097 0.0096
Echinococcus granulosus integrin alpha 3 0.024 0.0273 0.0273
Giardia lamblia High cysteine protein 0.0089 0.0085 0.0167
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0032 0.0012 0.0184
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0365 0.043 1
Leishmania major sir2-family protein-like protein 0.0049 0.0034 0.051
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Trichomonas vaginalis conserved hypothetical protein 0.1595 0.1976 0.3231
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0365 0.043 0.043
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0049 0.0034 0.0521
Giardia lamblia Sirtuin type 2 0.0049 0.0034 0.0026
Echinococcus granulosus discoidin domain receptor 0.0035 0.0017 0.0016
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0331 0.0388 0.8455
Mycobacterium ulcerans monoamine oxidase 0.0099 0.0097 0.225
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0027 0.0006 0.0129
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0251 0.0287 0.0359
Echinococcus granulosus lysine specific histone demethylase 1A 0.0488 0.0585 0.0585
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.1595 0.1976 0.3231
Loa Loa (eye worm) hypothetical protein 0.053 0.0637 0.0637
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0099 0.0097 0.225
Loa Loa (eye worm) WD40 repeat protein 0.0134 0.0141 0.014
Entamoeba histolytica PH domain containing protein kinase, putative 0.007 0.006 0.0985
Leishmania major silent information regulator 2, putative 0.0331 0.0388 0.8987
Loa Loa (eye worm) hypothetical protein 0.0133 0.014 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Plasmodium falciparum subtilisin-like protease 3 0.0365 0.043 0.6791
Loa Loa (eye worm) TK/ROR protein kinase 0.0032 0.0012 0.0012
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0228 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0089 0.0085 0.0084
Trypanosoma cruzi UDP-galactopyranose mutase 0.0099 0.0097 0.1905
Echinococcus granulosus adam 17 protease 0.0095 0.0091 0.009
Echinococcus granulosus neuroendocrine convertase 2 0.5054 0.6319 0.6319
Schistosoma mansoni protein kinase 0.0123 0.0127 0.0126
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0028 0.0008 0.0178
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.196 0.2434 0.398
Loa Loa (eye worm) angiogenesis inhibito 0.0063 0.0051 0.0051
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0386 0.0456 1
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0033 0.0013 0.0013
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0237 0.0269 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0024 0.0038
Echinococcus multilocularis MAM 0.0046 0.003 0.0037
Echinococcus granulosus furin 0.7984 1 1
Trichomonas vaginalis conserved hypothetical protein 0.1595 0.1976 0.3231
Giardia lamblia Transcriptional regulator, Sir2 family 0.0049 0.0034 0.0026
Schistosoma mansoni hypothetical protein 0.0033 0.0013 0.0013
Echinococcus granulosus Furin 1 0.196 0.2434 0.2434
Trichomonas vaginalis hypothetical protein 0.0089 0.0085 0.0137
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Echinococcus multilocularis protoporphyrinogen oxidase 0.0099 0.0097 0.012
Loa Loa (eye worm) hypothetical protein 0.0067 0.0057 0.0056
Plasmodium vivax NAD-dependent deacetylase, putative 0.0049 0.0034 0.0521
Toxoplasma gondii subtilisin SUB11 0.0365 0.043 0.6791
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0049 0.0034 0.048
Brugia malayi hypothetical protein 0.0099 0.0097 0.0096
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0365 0.043 0.043
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0365 0.043 0.043
Trichomonas vaginalis conserved hypothetical protein 0.0365 0.043 0.0703
Onchocerca volvulus 0.0365 0.043 0.6747
Schistosoma mansoni protein kinase 0.0123 0.0127 0.0126
Echinococcus multilocularis NMDA receptor 0.0033 0.0013 0.0016
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0033 0.0013 0.0016
Loa Loa (eye worm) proprotein convertase 2 0.196 0.2434 0.2434
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0057 0.0044 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.1595 0.1976 0.3231
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0034 0.0054
Toxoplasma gondii histone deacetylase SIR2-like 0.0049 0.0034 0.0521
Mycobacterium ulcerans Type I modular polyketide synthase 0.0027 0.0006 0.0129
Onchocerca volvulus 0.053 0.0637 1
Onchocerca volvulus 0.0046 0.003 0.0462
Mycobacterium ulcerans polyketide synthase 0.0028 0.0008 0.0178
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0026 0.0005 0.0106
Onchocerca volvulus 0.0138 0.0145 0.227
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0027 0.0006 0.0129
Loa Loa (eye worm) fatty acid synthase 0.0026 0.0005 0.0005
Echinococcus multilocularis nmda type glutamate receptor 0.0116 0.0118 0.0147
Giardia lamblia Tenascin-like 0.0089 0.0085 0.0167
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0049 0.0034 0.0033
Onchocerca volvulus Fatty acid synthase homolog 0.0048 0.0032 0.05
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0049 0.0034 0.026
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0034 0.0054
Loa Loa (eye worm) hypothetical protein 0.0089 0.0085 0.0084
Giardia lamblia Tenascin precursor 0.0089 0.0085 0.0167
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0034 0.0054
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Echinococcus granulosus integrin beta 2 0.3103 0.387 0.387
Echinococcus granulosus disintegrin and metalloproteinase 0.0095 0.0091 0.009
Schistosoma mansoni ATP-binding cassette transporter 0.0033 0.0013 0.0013
Toxoplasma gondii type I fatty acid synthase, putative 0.0028 0.0008 0.0112
Schistosoma mansoni hypothetical protein 0.0035 0.0017 0.0016
Loa Loa (eye worm) integrin beta-2 0.4206 0.5255 0.5254
Trichomonas vaginalis conserved hypothetical protein 0.1595 0.1976 0.3231
Mycobacterium tuberculosis Conserved hypothetical protein 0.0099 0.0097 0.225
Echinococcus multilocularis membrane bound transcription factor site 1 0.0365 0.043 0.0537
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Loa Loa (eye worm) apoptosis regulator protein 0.0057 0.0044 0.0043
Giardia lamblia High cysteine protein 0.0089 0.0085 0.0167
Loa Loa (eye worm) transcriptional regulator 0.0049 0.0034 0.0033
Echinococcus multilocularis glutamate receptor 2 0.0049 0.0034 0.0042
Trypanosoma cruzi UDP-galactopyranose mutase 0.0099 0.0097 0.1905
Onchocerca volvulus 0.0089 0.0085 0.1319
Loa Loa (eye worm) integrin alpha pat-2 0.0482 0.0578 0.0578
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0033 0.0013 0.0013
Brugia malayi transcriptional regulator, Sir2 family protein 0.0049 0.0034 0.0033
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.125 0.1542 0.1542
Loa Loa (eye worm) hypothetical protein 0.7984 1 1
Mycobacterium tuberculosis Polyketide synthase Pks13 0.004 0.0022 0.0513
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0027 0.0006 0.0129
Echinococcus granulosus protein kinase c epsilon type 0.0085 0.008 0.0079
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0123 0.0127 0.0158
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0287 0.0287
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0034 0.0054
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.4891 0.6115 1
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0099 0.0097 0.1521
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0713 0.0868 0.1085
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0049 0.0034 0.0034
Schistosoma mansoni amine oxidase 0.0099 0.0097 0.0096
Echinococcus multilocularis Furin 1 0.196 0.2434 0.3043
Echinococcus multilocularis Tolloid protein 1 0.0034 0.0015 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Toxoplasma gondii subtilisin SUB2 0.0365 0.043 0.6791
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0107 0.0107 0.0107
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0033 0.0013 0.0013
Brugia malayi amine oxidase, flavin-containing family protein 0.0141 0.0149 0.0148
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0049 0.0034 0.0033
Echinococcus granulosus protein will die slowly 0.0134 0.0141 0.014
Toxoplasma gondii histone deacetylase SIR2 0.0049 0.0034 0.0521
Giardia lamblia Hypothetical protein 0.0331 0.0388 0.1002
Mycobacterium leprae PROBABLE CONSERVED TRANSMEMBRANE PROTEIN 0.0035 0.0017 0.0386
Echinococcus granulosus discoidin domain containing receptor 2 0.0035 0.0017 0.0016
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0365 0.043 1
Brugia malayi Integrin beta pat-3 precursor 0.4206 0.5255 0.5254
Plasmodium falciparum cysteine repeat modular protein 1 0.0032 0.0012 0.0184
Mycobacterium leprae Probable polyketide synthase Pks1 0.0028 0.0008 0.0178
Brugia malayi Reprolysin 0.0134 0.014 0.0139
Brugia malayi EGF-like domain containing protein 0.0089 0.0085 0.0084
Echinococcus granulosus fibrillin 2 0.0089 0.0085 0.0084
Loa Loa (eye worm) hypothetical protein 0.0488 0.0585 0.0585
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.196 0.2434 0.398
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0331 0.0388 0.0633
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0027 0.0006 0.0005
Onchocerca volvulus Putative cubilin 0.003 0.001 0.0146
Schistosoma mansoni septate junction protein 0.0044 0.0028 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.008 0.0079
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Plasmodium vivax hypothetical protein, conserved 0.0049 0.0034 0.0521
Echinococcus multilocularis epidermal growth factor receptor 0.054 0.0651 0.0813
Schistosoma mansoni hypothetical protein 0.0032 0.0012 0.0012
Brugia malayi transcriptional regulator, Sir2 family protein 0.0049 0.0034 0.0033
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0275 0.0318 0.0397
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.196 0.2434 0.2434
Schistosoma mansoni btb and poz domain-containing protein 0.0035 0.0017 0.0016
Plasmodium vivax subtilisin-like protease 1 0.0526 0.0633 1
Schistosoma mansoni integrin beta subunit 0.2457 0.3058 0.3058
Brugia malayi EGF-like domain containing protein 0.0089 0.0085 0.0084
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Schistosoma mansoni chromatin regulatory protein sir2 0.0049 0.0034 0.0033
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0049 0.0034 0.0042
Mycobacterium ulcerans Type I modular polyketide synthase 0.0027 0.0006 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Loa Loa (eye worm) hypothetical protein 0.0069 0.0059 0.0059
Toxoplasma gondii subtilisin SUB6 0.0365 0.043 0.6791
Echinococcus granulosus nmda type glutamate receptor 0.0116 0.0118 0.0118
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.7984 1 1
Schistosoma mansoni discoidin domain receptor 0.0035 0.0017 0.0016
Schistosoma mansoni glutamate receptor kainate 0.0033 0.0013 0.0013
Brugia malayi celfurPC protein 0.6389 0.7996 0.7996
Toxoplasma gondii F5/8 type C domain-containing protein 0.0035 0.0017 0.0254
Echinococcus multilocularis discoidin domain receptor 0.0035 0.0017 0.002
Trichomonas vaginalis conserved hypothetical protein 0.1595 0.1976 0.3231
Loa Loa (eye worm) hypothetical protein 0.0032 0.0012 0.0012
Echinococcus multilocularis Coagulation factor 5 8 type, C terminal 0.0035 0.0017 0.002
Brugia malayi Furin-like cysteine rich region family protein 0.054 0.0651 0.065
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.005 0.0035 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0365 0.043 0.0703
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0049 0.0034 0.026
Plasmodium falciparum LCCL domain-containing protein 0.0035 0.0017 0.0254
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0331 0.0388 1
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0026 0.0005 0.0106
Brugia malayi SWIRM domain containing protein 0.053 0.0637 0.0637
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0365 0.043 1
Brugia malayi hypothetical protein 0.0646 0.0784 0.0783
Schistosoma mansoni chromatin regulatory protein sir2 0.0331 0.0388 0.0387
Loa Loa (eye worm) hypothetical protein 0.0063 0.0051 0.0051
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0028 0.0008 0.0178
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0034 0.0054
Brugia malayi SWIRM domain containing protein 0.0041 0.0024 0.0024
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0027 0.0006 0.0129
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0028 0.0008 0.0178
Mycobacterium ulcerans NAD-dependent deacetylase 0.0049 0.0034 0.0779
Brugia malayi Integrin alpha pat-2 precursor 0.0313 0.0365 0.0365
Onchocerca volvulus 0.0046 0.003 0.0462
Loa Loa (eye worm) hypothetical protein 0.0099 0.0097 0.0096
Mycobacterium ulcerans Sir2-like regulatory protein 0.0049 0.0034 0.0779
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0017 0.0026
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Onchocerca volvulus 0.0035 0.0017 0.0252
Echinococcus multilocularis 0.6389 0.7996 1
Toxoplasma gondii histone lysine-specific demethylase 0.0099 0.0097 0.1521
Echinococcus granulosus Tolloid protein 1 0.0034 0.0015 0.0014
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0007 0.0006
Mycobacterium ulcerans polyketide synthase 0.0027 0.0006 0.0129
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0028 0.0008 0.0178
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0365 0.043 1
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.4891 0.6115 0.7647
Echinococcus multilocularis integrin alpha 3 0.024 0.0273 0.0341
Echinococcus granulosus chromatin regulatory protein sir2 0.0331 0.0388 0.0387
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0084 0.0077 0.1794
Loa Loa (eye worm) hypothetical protein 0.0246 0.0281 0.028
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0099 0.0097 0.1521
Mycobacterium ulcerans dehydrogenase 0.0099 0.0097 0.225
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0365 0.043 0.043
Schistosoma mansoni apoptosis regulator bax 0.0057 0.0044 0.0043
Toxoplasma gondii subtilisin SUB9 0.0365 0.043 0.6791
Echinococcus granulosus integrin alpha ps 0.0067 0.0057 0.0056
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0299 0.0347 0.0347
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Loa Loa (eye worm) hypothetical protein 0.0095 0.0091 0.009
Entamoeba histolytica hypothetical protein, conserved 0.0049 0.0034 0.026
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.4891 0.6115 0.6115
Brugia malayi EGF-like domain containing protein 0.0089 0.0085 0.0084
Loa Loa (eye worm) sirtuin 4 0.0049 0.0034 0.0033
Echinococcus multilocularis adam 0.0388 0.046 0.0574
Echinococcus granulosus adam 0.0388 0.046 0.0459
Loa Loa (eye worm) hypothetical protein 0.0073 0.0064 0.0063
Toxoplasma gondii subtilisin SUB7 0.0365 0.043 0.6791
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.196 0.2434 0.398
Giardia lamblia Furin precursor putative serine protease 0.1595 0.1976 0.5379
Loa Loa (eye worm) subtilase 0.0365 0.043 0.043
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Loa Loa (eye worm) hypothetical protein 0.0173 0.0189 0.0188
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0034 0.0054
Schistosoma mansoni hypothetical protein 0.0057 0.0044 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0365 0.043 0.0703
Loa Loa (eye worm) hypothetical protein 0.0099 0.0097 0.0096
Echinococcus multilocularis serine:threonine protein kinase N2 0.0078 0.007 0.0087
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0365 0.043 0.0703
Plasmodium falciparum subtilisin-like protease 2 0.0365 0.043 0.6791
Schistosoma mansoni glutamate receptor NMDA 0.0275 0.0318 0.0317
Trichomonas vaginalis hypothetical protein 0.0035 0.0017 0.0026

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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