TDR Targets

Basic information

Technical information

TDR Targets ID: 883730
Name: butyl 2-[[3-(diethylcarbamoyl)piperidine-1-ca rbonyl]amino]benzoate
MW: 403.515 | Formula: C22H33N3O4
H donors: 1 H acceptors: 3 LogP: 3.45 Rotable bonds: 12
Rule of 5 violations (Lipinski): 1
SMILES: CCCCOC(=O)c1ccccc1NC(=O)N1CCCC(C1)C(=O)N(CC)CC
InChi: 1S/C22H33N3O4/c1-4-7-15-29-21(27)18-12-8-9-13-19(18)23-22(28)25-14-10-11-17(16-25)20(26)24(5-2)6-3/h8-9,12-13,17H,4-7,10-11,14-16H2,1-3H3,(H,23,28)
InChiKey: HIVBOBKLZIWKHT-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

2-[[[3-(diethylamino-oxomethyl)-1-piperidinyl]-oxomethyl]amino]benzoic acid butyl ester
2-[[3-(diethylcarbamoyl)piperidine-1-carbonyl]amino]benzoic acid butyl ester
butyl 2-[[3-(diethylcarbamoyl)piperidin-1-yl]carbonylamino]benzoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	7tm_1 domain containing protein	0.0091	0.0247	0.023
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.007	0.0123	0.0105
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0054	0.0031	0.0013
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0142	0.0555	0.0539
Echinococcus multilocularis	neuropeptides capa receptor	0.0091	0.0247	0.03
Brugia malayi	G-protein coupled receptor	0.0091	0.0247	0.023
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Brugia malayi	hypothetical protein	0.0091	0.0247	0.023
Loa Loa (eye worm)	peptidase family M1 containing protein	0.0192	0.0854	0.0838
Trichomonas vaginalis	conserved hypothetical protein	0.0388	0.2032	0.3847
Echinococcus multilocularis		0.0054	0.0031	0.0017
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Brugia malayi	Trypsin family protein	0.0106	0.0338	0.0321
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Loa Loa (eye worm)	hypothetical protein	0.0093	0.0262	0.0245
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Onchocerca volvulus		0.0091	0.0247	0.1696
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0311	0.1569	0.1554
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0091	0.0247	0.03
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0054	0.0031	0.064
Schistosoma mansoni	neuropeptide receptor	0.0091	0.0247	0.023
Onchocerca volvulus		0.0093	0.0262	0.1796
Mycobacterium tuberculosis	Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase)	0.0161	0.067	0.5481
Echinococcus multilocularis	somatostatin receptor	0.0091	0.0247	0.03
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.007	0.0123	0.0137
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Loa Loa (eye worm)	neuropeptide F receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	TYRA-2 protein	0.0091	0.0247	0.023
Echinococcus multilocularis	protoporphyrinogen oxidase	0.0054	0.0031	0.0017
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Echinococcus multilocularis	orexin receptor type 2	0.0091	0.0247	0.03
Brugia malayi	Peptidase family M13 containing protein	0.0188	0.0829	0.0813
Toxoplasma gondii	subtilisin SUB5	0.0086	0.0219	0.2355
Toxoplasma gondii	subtilisin SUB9	0.0086	0.0219	0.2355
Brugia malayi	neuropeptide F receptor	0.0091	0.0247	0.023
Echinococcus multilocularis	fmrfamide receptor	0.0091	0.0247	0.03
Echinococcus multilocularis	neuropeptide receptor	0.0091	0.0247	0.03
Trypanosoma brucei	serine peptidase, clan SB, family S8-like protein	0.0086	0.0219	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0091	0.0247	0.023
Echinococcus granulosus	fmrfamide receptor	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0524	0.2841	0.538
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0031	0.0013
Plasmodium vivax	subtilisin-like protease 1	0.0086	0.0219	0.293
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0091	0.0247	0.03
Trichomonas vaginalis	cyclin A, putative	0.0052	0.0018	0.0033
Mycobacterium ulcerans	aminopeptidase N PepN	0.007	0.0123	0.0789
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Trypanosoma cruzi	Aminopeptidase M1, putative	0.007	0.0123	0.522
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.007	0.0123	0.0137
Trypanosoma cruzi	subtilisin peptidase	0.0086	0.0219	1
Echinococcus multilocularis	G protein coupled receptor 139	0.0091	0.0247	0.03
Trypanosoma brucei	Aminopeptidase M1, putative	0.007	0.0123	0.522
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Echinococcus multilocularis	lysine specific histone demethylase 1A	0.0268	0.1309	0.1687
Echinococcus multilocularis	neuropeptide Y receptor	0.0091	0.0247	0.03
Schistosoma mansoni	tripeptidyl-peptidase II (S08 family)	0.0086	0.0219	0.0201
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0524	0.2841	0.538
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Leishmania major	aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1	0.007	0.0123	0.073
Echinococcus granulosus	neuropeptides capa receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0188	0.0829	0.0813
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0091	0.0247	0.03
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0139	0.0536	0.0519
Loa Loa (eye worm)	G-protein coupled receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	cuticular endochitinase	0.0292	0.1456	0.144
Brugia malayi	Endochitinase	0.0292	0.1456	0.144
Echinococcus granulosus	somatostatin receptor	0.0091	0.0247	0.023
Echinococcus multilocularis	neuropeptides capa receptor	0.0091	0.0247	0.03
Brugia malayi	Peptidase family M1 containing protein	0.007	0.0123	0.0105
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0091	0.0247	0.023
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.0162	0.0673	1
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Trypanosoma cruzi	serine peptidase, clan SB, family S8-like protein	0.0086	0.0219	1
Onchocerca volvulus	Putative endochitinase	0.0292	0.1456	1
Onchocerca volvulus		0.0091	0.0247	0.1696
Schistosoma mansoni	cytosol alanyl aminopeptidase (M01 family)	0.007	0.0123	0.0105
Schistosoma mansoni	amine oxidase	0.0054	0.0031	0.0013
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0091	0.0247	0.023
Schistosoma mansoni	Lysine-specific histone demethylase 1	0.0268	0.1309	0.1294
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0091	0.0247	0.03
Echinococcus multilocularis	dro:myosuppressin receptor	0.0091	0.0247	0.03
Brugia malayi	larval opioid receptor	0.0091	0.0247	0.023
Brugia malayi	celfurPC protein	0.133	0.7673	0.7669
Echinococcus granulosus	rhodopsin orphan GPCR	0.0091	0.0247	0.023
Mycobacterium tuberculosis	Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5)	0.0086	0.0219	0.1612
Loa Loa (eye worm)	hypothetical protein	0.0188	0.0829	0.0813
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.007	0.0123	0.0137
Schistosoma mansoni	Protoporphyrinogen oxidase chloroplast/mitochondrial precursor	0.0054	0.0031	0.0013
Brugia malayi	SWIRM domain containing protein	0.029	0.1445	0.143
Trichomonas vaginalis	conserved hypothetical protein	0.0086	0.0219	0.0414
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0091	0.0247	0.023
Schistosoma mansoni	intracisternal A-particle retropepsin (A02 family)	0.1225	0.7044	0.7039
Echinococcus granulosus	orexin receptor type 2	0.0091	0.0247	0.023
Trypanosoma cruzi	metallo-peptidase, clan MA(E), family M1, putative	0.007	0.0123	0.522
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Mycobacterium leprae	probable zinc metalloprotease	0.0188	0.0829	1
Schistosoma mansoni	neuropeptide F-like receptor	0.0091	0.0247	0.023
Toxoplasma gondii	subtilisin SUB2	0.0086	0.0219	0.2355
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.0085	0.0214	0.0197
Loa Loa (eye worm)	hypothetical protein	0.0077	0.0166	0.0149
Echinococcus multilocularis	endothelin converting enzyme 1	0.0188	0.0829	0.106
Mycobacterium tuberculosis	Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like)	0.0086	0.0219	0.1612
Brugia malayi	hypothetical protein	0.0054	0.0031	0.0013
Brugia malayi	amine oxidase, flavin-containing family protein	0.0077	0.0166	0.0149
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.007	0.0123	0.0105
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0091	0.0247	0.023
Echinococcus granulosus	dro:myosuppressin receptor	0.0091	0.0247	0.023
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0091	0.0247	0.03
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0188	0.0829	0.0813
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0311	0.1569	0.2027
Schistosoma mansoni	hypothetical protein	0.0388	0.2032	0.2018
Schistosoma mansoni	opsin-like receptor	0.0091	0.0247	0.023
Schistosoma mansoni	amine GPCR	0.0091	0.0247	0.023
Brugia malayi	hypothetical protein	0.0091	0.0247	0.023
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0091	0.0247	0.03
Trichomonas vaginalis	conserved hypothetical protein	0.0388	0.2032	0.3847
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0091	0.0247	0.03
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.1718	1	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0091	0.0247	0.023
Onchocerca volvulus	Putative endochitinase	0.0292	0.1456	1
Echinococcus multilocularis	Furin 1	0.0524	0.2841	0.3689
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0091	0.0247	0.03
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0091	0.0247	0.03
Toxoplasma gondii	subtilisin SUB11	0.0086	0.0219	0.2355
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0091	0.0247	0.03
Loa Loa (eye worm)	hypothetical protein	0.0142	0.0555	0.0539
Echinococcus multilocularis	serotonin receptor	0.0091	0.0247	0.03
Trichomonas vaginalis	cyclin B, putative	0.0052	0.0018	0.0033
Echinococcus granulosus	g protein coupled receptor	0.0091	0.0247	0.023
Brugia malayi	hypothetical protein	0.0091	0.0247	0.023
Schistosoma mansoni	hypothetical protein	0.0091	0.0247	0.023
Brugia malayi	hypothetical protein	0.0091	0.0247	0.023
Onchocerca volvulus		0.0091	0.0247	0.1696
Echinococcus multilocularis	neuropeptide receptor A26	0.0091	0.0247	0.03
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0091	0.0247	0.023
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0091	0.0247	0.023
Trichomonas vaginalis	conserved hypothetical protein	0.0388	0.2032	0.3847
Brugia malayi	proprotein convertase 2	0.1311	0.756	0.7556
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Brugia malayi	Dopamine receptor protein 2	0.0091	0.0247	0.023
Echinococcus granulosus	biogenic amine 5HT receptor	0.0091	0.0247	0.023
Mycobacterium ulcerans	proline rich membrane-anchored mycosin MycP5	0.0086	0.0219	0.1612
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0054	0.0031	0.064
Schistosoma mansoni	neuropeptide receptor	0.0091	0.0247	0.023
Echinococcus granulosus	neuropeptide Y receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Echinococcus granulosus	g protein coupled receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Schistosoma mansoni	amine GPCR	0.0091	0.0247	0.023
Plasmodium vivax	subtilisin-like serine protease, putative	0.0086	0.0219	0.293
Brugia malayi	endochitinase	0.0292	0.1456	0.144
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Echinococcus multilocularis	g-protein coupled receptor	0.0091	0.0247	0.03
Loa Loa (eye worm)	subtilase	0.0086	0.0219	0.0201
Brugia malayi	hypothetical protein	0.0091	0.0247	0.023
Trichomonas vaginalis	conserved hypothetical protein	0.0388	0.2032	0.3847
Brugia malayi	Subtilase family protein	0.0086	0.0219	0.0201
Toxoplasma gondii	subtilisin SUB4	0.0086	0.0219	0.2355
Schistosoma mansoni	biogenic amine receptor	0.0091	0.0247	0.023
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	neuropeptide F receptor	0.0091	0.0247	0.023
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0268	0.1309	0.1294
Echinococcus granulosus	tm gpcr rhodopsin	0.0091	0.0247	0.023
Trichomonas vaginalis	conserved hypothetical protein	0.0086	0.0219	0.0414
Echinococcus multilocularis	sex peptide receptor	0.0091	0.0247	0.03
Mycobacterium tuberculosis	Possible chitinase	0.0249	0.1198	1
Onchocerca volvulus		0.0091	0.0247	0.1696
Echinococcus multilocularis	sortilin	0.0068	0.0111	0.0122
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0524	0.2841	0.538
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Schistosoma mansoni	site-1 peptidase (S08 family)	0.0086	0.0219	0.0201
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Loa Loa (eye worm)	hypothetical protein	0.0268	0.1309	0.1294
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0031	0.0013
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0091	0.0247	0.023
Echinococcus granulosus	neuropeptide receptor A26	0.0091	0.0247	0.023
Plasmodium falciparum	subtilisin-like protease 3	0.0086	0.0219	0.293
Schistosoma mansoni	neuropeptide receptor	0.0091	0.0247	0.023
Mycobacterium leprae	PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3)	0.0086	0.0219	0.2355
Trypanosoma cruzi	aminopeptidase, putative	0.007	0.0123	0.522
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Echinococcus multilocularis	neuropeptide s receptor	0.0091	0.0247	0.03
Brugia malayi	Melatonin receptor type 1A	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Plasmodium vivax	subtilisin-like protease 2, putative	0.0086	0.0219	0.293
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0091	0.0247	0.03
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Brugia malayi	Serotonin receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Onchocerca volvulus	Putative endochitinase	0.0292	0.1456	1
Trichomonas vaginalis	conserved hypothetical protein	0.0388	0.2032	0.3847
Loa Loa (eye worm)	hypothetical protein	0.0106	0.0338	0.0321
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.007	0.0123	0.0105
Schistosoma mansoni	myosin xvIII	0.0091	0.0247	0.023
Mycobacterium ulcerans	chitinase/cellulase	0.0249	0.1198	1
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0139	0.0536	0.0519
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0091	0.0247	0.023
Trichomonas vaginalis	conserved hypothetical protein	0.0388	0.2032	0.3847
Toxoplasma gondii	cathepsin CPC2	0.0162	0.0673	0.8037
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0095	0.0272	0.0255
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0091	0.0247	0.03
Schistosoma mansoni	opsin-like receptor	0.0091	0.0247	0.023
Schistosoma mansoni	hypothetical protein	0.0091	0.0247	0.023
Entamoeba histolytica	aminopeptidase, putative	0.007	0.0123	0.073
Schistosoma mansoni	neuropeptide f receptor 76f	0.0091	0.0247	0.023
Brugia malayi	Peptidase family M1 containing protein	0.0237	0.1125	0.1109
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Echinococcus multilocularis	membrane bound transcription factor site 1	0.0086	0.0219	0.0263
Leishmania major	chitinase	0.0292	0.1456	1
Toxoplasma gondii	subtilisin SUB12	0.0086	0.0219	0.2355
Brugia malayi	hypothetical protein	0.0091	0.0247	0.023
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0091	0.0247	0.03
Echinococcus granulosus	rhodopsin orphan GPCR	0.0091	0.0247	0.023
Brugia malayi	Membrane-bound transcription factor site-1 protease precursor	0.0086	0.0219	0.0201
Trichomonas vaginalis	conserved hypothetical protein	0.0086	0.0219	0.0414
Brugia malayi	ORL1-like opioid receptor	0.0091	0.0247	0.023
Toxoplasma gondii	subtilisin SUB1	0.0086	0.0219	0.2355
Mycobacterium tuberculosis	Probable zinc metalloprotease Zmp1	0.0188	0.0829	0.6845
Brugia malayi	Hypothetical subtilase-type proteinase F21H12.6 in chromosome II	0.0086	0.0219	0.0201
Brugia malayi	putative neuropeptide receptor NPR1	0.0091	0.0247	0.023
Mycobacterium leprae	Possible secreted protease	0.0086	0.0219	0.2355
Schistosoma mansoni	neprilysin-2 (M13 family)	0.0095	0.0272	0.0255
Trypanosoma brucei	subtilisin peptidase	0.0086	0.0219	1
Brugia malayi	Hypothetical zinc metalloproteinase T16A9.4	0.0188	0.0829	0.0813
Echinococcus multilocularis	g protein coupled receptor	0.0091	0.0247	0.03
Trichomonas vaginalis	proprotein convertase subtilisin/kexin type, putative	0.0438	0.2327	0.4407
Onchocerca volvulus		0.0091	0.0247	0.1696
Schistosoma mansoni	adenoreceptor	0.0091	0.0247	0.023
Schistosoma mansoni	site-1 peptidase (S08 family)	0.0086	0.0219	0.0201
Onchocerca volvulus		0.0091	0.0247	0.1696
Onchocerca volvulus		0.0091	0.0247	0.1696
Onchocerca volvulus		0.0091	0.0247	0.1694
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.007	0.0123	0.0105
Trichomonas vaginalis	neuroendocrine convertase 2 precursor, putative	0.0438	0.2327	0.4407
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Schistosoma mansoni	neuropeptide F-like receptor	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0135	0.0514	0.0974
Toxoplasma gondii	subtilisin SUB8	0.0086	0.0219	0.2355
Brugia malayi	Dopamine receptor	0.0091	0.0247	0.023
Echinococcus multilocularis	neuropeptide Y receptor	0.0091	0.0247	0.03
Brugia malayi	hypothetical protein	0.0091	0.0247	0.023
Echinococcus multilocularis	neuropeptide receptor	0.0091	0.0247	0.03
Echinococcus multilocularis	g protein coupled receptor	0.0091	0.0247	0.03
Trypanosoma cruzi	subtilisin-like serine peptidase, putative	0.0086	0.0219	1
Echinococcus multilocularis	allatostatin A receptor	0.0091	0.0247	0.03
Schistosoma mansoni	amine GPCR	0.0091	0.0247	0.023
Brugia malayi	follicle stimulating hormone receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Schistosoma mansoni	family M13 non-peptidase homologue (M13 family)	0.0095	0.0272	0.0255
Echinococcus multilocularis	Peptidase S8 S53, subtilisin kexin sedolisin	0.0086	0.0219	0.0263
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.007	0.0123	0.0232
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0091	0.0247	0.03
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0091	0.0247	0.023
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Echinococcus granulosus	neuroendocrine convertase 2	0.1311	0.756	0.7556
Chlamydia trachomatis	protoporphyrinogen oxidase	0.0054	0.0031	0.5
Brugia malayi	G-protein coupled receptor	0.0091	0.0247	0.023
Giardia lamblia	High cysteine membrane protein Group 2	0.0456	0.244	1
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Leishmania major	subtilisin-like serine peptidase	0.0086	0.0219	0.1398
Loa Loa (eye worm)	microfilarial chitinase	0.0249	0.1198	0.1182
Loa Loa (eye worm)	aminopeptidase N	0.007	0.0123	0.0105
Loa Loa (eye worm)	endoprotease bli-4	0.1718	1	1
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Loa Loa (eye worm)	hypothetical protein	0.0311	0.1569	0.1554
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0091	0.0247	0.023
Echinococcus multilocularis	Peptidase M1, membrane alanine aminopeptidase, N terminal	0.007	0.0123	0.0137
Loa Loa (eye worm)	proprotein convertase 2	0.0524	0.2841	0.2829
Loa Loa (eye worm)	hypothetical protein	0.0139	0.0536	0.0519
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Brugia malayi	hypothetical protein	0.0091	0.0247	0.023
Echinococcus granulosus	neuropeptide receptor	0.0091	0.0247	0.023
Echinococcus multilocularis	g protein coupled receptor	0.0091	0.0247	0.03
Echinococcus granulosus	rhodopsin orphan GPCR	0.0091	0.0247	0.023
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0091	0.0247	0.03
Loa Loa (eye worm)	hypothetical protein	0.0837	0.4719	0.471
Echinococcus multilocularis	neuroendocrine convertase 2	0.1311	0.756	0.9853
Loa Loa (eye worm)	hypothetical protein	0.0213	0.0978	0.0962
Loa Loa (eye worm)	hypothetical protein	0.0188	0.0829	0.0813
Toxoplasma gondii	subtilisin SUB10	0.0086	0.0219	0.2355
Onchocerca volvulus		0.0091	0.0247	0.1696
Mycobacterium ulcerans	chitinase/cellulase	0.0249	0.1198	1
Plasmodium falciparum	sortilin	0.0068	0.0111	0.1254
Onchocerca volvulus		0.0091	0.0247	0.1696
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0091	0.0247	0.023
Trichomonas vaginalis	conserved hypothetical protein	0.0388	0.2032	0.3847
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0091	0.0247	0.03
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Schistosoma mansoni	neuropeptide receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0106	0.0338	0.0321
Schistosoma mansoni	growth hormone secretagogue receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0142	0.0555	0.0539
Trichomonas vaginalis	hypothetical protein	0.0388	0.2032	0.3847
Toxoplasma gondii	subtilisin SUB7	0.0086	0.0219	0.2355
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Onchocerca volvulus		0.0091	0.0247	0.1696
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0091	0.0247	0.1696
Loa Loa (eye worm)	hypothetical protein	0.0139	0.0536	0.0519
Schistosoma mansoni	tyrosine kinase	0.0259	0.1254	0.1239
Trichomonas vaginalis	leucine-rich repeat protein, BspA family	0.0388	0.2032	0.3847
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Echinococcus multilocularis	fmrfamide receptor	0.0091	0.0247	0.03
Onchocerca volvulus		0.029	0.1445	0.9926
Brugia malayi	G protein-coupled receptor F59B2.13	0.0091	0.0247	0.023
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0142	0.0555	0.0539
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0524	0.2841	0.538
Trypanosoma brucei	metallo-peptidase, Clan MA(E) Family M1	0.007	0.0123	0.522
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0091	0.0247	0.023
Echinococcus granulosus	peptidase s8 s53 subtilisin kexin sedolisin	0.0086	0.0219	0.0201
Echinococcus multilocularis	proprotein convertase subtilisin:kexin type 5	0.0931	0.5281	0.6876
Trichomonas vaginalis	cyclins, putative	0.0052	0.0018	0.0033
Loa Loa (eye worm)	hypothetical protein	0.0361	0.1868	0.1854
Schistosoma mansoni	biogenic amine receptor	0.0091	0.0247	0.023
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0106	0.0338	0.0321
Plasmodium falciparum	dipeptidyl aminopeptidase 3	0.0162	0.0673	1
Brugia malayi	hypothetical protein	0.0091	0.0247	0.023
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0091	0.0247	0.023
Echinococcus granulosus	rhodopsin orphan GPCR	0.0091	0.0247	0.023
Brugia malayi	Dopamine receptor protein 1	0.0091	0.0247	0.023
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0091	0.0247	0.023
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0091	0.0247	0.023
Trypanosoma brucei	Aminopeptidase M1, putative	0.007	0.0123	0.522
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Echinococcus multilocularis	epidermal growth factor receptor	0.0259	0.1254	0.1616
Echinococcus granulosus	furin	0.1718	1	1
Echinococcus granulosus	neuropeptide Y receptor	0.0091	0.0247	0.023
Echinococcus granulosus	neuropeptide FF receptor 2	0.0311	0.1569	0.1554
Mycobacterium tuberculosis	Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4)	0.0086	0.0219	0.1612
Schistosoma mansoni	amine GPCR	0.0091	0.0247	0.023
Trypanosoma cruzi	subtilisin-like serine peptidase, putative	0.0086	0.0219	1
Echinococcus granulosus	proprotein convertase subtilisin:kexin type 5	0.0931	0.5281	0.5273
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0091	0.0247	0.03
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0091	0.0247	0.03
Echinococcus granulosus	biogenic amine 5HT receptor	0.0091	0.0247	0.023
Mycobacterium ulcerans	zinc metalloprotease	0.0188	0.0829	0.6845
Loa Loa (eye worm)	hypothetical protein	0.0142	0.0555	0.0539
Echinococcus granulosus	endothelin converting enzyme 1	0.0188	0.0829	0.0813
Onchocerca volvulus		0.0106	0.0338	0.2322
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.007	0.0123	0.0137
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Brugia malayi	hypothetical protein	0.007	0.0123	0.0105
Brugia malayi	Serotonin receptor	0.0091	0.0247	0.023
Trichomonas vaginalis	conserved hypothetical protein	0.0388	0.2032	0.3847
Trichomonas vaginalis	conserved hypothetical protein	0.0388	0.2032	0.3847
Onchocerca volvulus		0.0086	0.0219	0.15
Echinococcus granulosus	g protein coupled receptor	0.0091	0.0247	0.023
Echinococcus granulosus	rhodopsin orphan GPCR	0.0091	0.0247	0.023
Trichomonas vaginalis	cyclin B, putative	0.0052	0.0018	0.0033
Trichomonas vaginalis	conserved hypothetical protein	0.0086	0.0219	0.0414
Loa Loa (eye worm)	hypothetical protein	0.029	0.1445	0.143
Trichomonas vaginalis	cyclins, putative	0.0052	0.0018	0.0033
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0091	0.0247	0.023
Echinococcus granulosus	g-protein coupled receptor	0.0091	0.0247	0.023
Trichomonas vaginalis	cyclins, putative	0.0052	0.0018	0.0033
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Echinococcus granulosus	rhodopsin orphan GPCR	0.0091	0.0247	0.023
Echinococcus granulosus	serotonin receptor	0.0091	0.0247	0.023
Brugia malayi	GnHR receptor homolog	0.0091	0.0247	0.023
Echinococcus granulosus	tm gpcr rhodopsin	0.0091	0.0247	0.023
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0091	0.0247	0.023
Schistosoma mansoni	amine GPCR	0.0091	0.0247	0.023
Schistosoma mansoni	biogenic amine receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0167	0.0707	0.069
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0091	0.0247	0.023
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0091	0.0247	0.023
Onchocerca volvulus	Putative endochitinase	0.0292	0.1456	1
Echinococcus granulosus	sortilin	0.0068	0.0111	0.0094
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0091	0.0247	0.023
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0524	0.2841	0.538
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0524	0.2841	0.538
Loa Loa (eye worm)	hypothetical protein	0.0142	0.0555	0.0539
Schistosoma mansoni	hypothetical protein	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Loa Loa (eye worm)	hypothetical protein	0.0268	0.1309	0.1294
Brugia malayi	AKH receptor	0.0091	0.0247	0.023
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0091	0.0247	0.023
Brugia malayi	sulfakinin receptor protein	0.0091	0.0247	0.023
Trichomonas vaginalis	conserved hypothetical protein	0.0086	0.0219	0.0414
Schistosoma mansoni	Nep2 peptidase (M13 family)	0.0095	0.0272	0.0255
Onchocerca volvulus		0.007	0.0123	0.0839
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.1718	1	1
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Echinococcus multilocularis		0.133	0.7673	1
Plasmodium falciparum	subtilisin-like protease 1	0.0086	0.0219	0.293
Toxoplasma gondii	sortilin, putative	0.0068	0.0111	0.1008
Trichomonas vaginalis	conserved hypothetical protein	0.0388	0.2032	0.3847
Toxoplasma gondii	subtilisin SUB6	0.0086	0.0219	0.2355
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0091	0.0247	0.023
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0139	0.0536	0.0519
Echinococcus granulosus	allatostatin A receptor	0.0091	0.0247	0.023
Onchocerca volvulus	Putative endochitinase	0.0292	0.1456	1
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0091	0.0247	0.023
Loa Loa (eye worm)	chitinase I	0.0292	0.1456	0.144
Giardia lamblia	Furin precursor putative serine protease	0.0438	0.2327	0.9535
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0091	0.0247	0.023
Plasmodium falciparum	subtilisin-like protease 2	0.0086	0.0219	0.293
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.007	0.0123	0.0137
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Loa Loa (eye worm)	G-protein coupled receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.007	0.0123	0.0232
Schistosoma mansoni	opsin-like receptor	0.0091	0.0247	0.023
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0091	0.0247	0.03
Onchocerca volvulus		0.0091	0.0247	0.1696
Echinococcus granulosus	7TM GPCR rhodopsin	0.0091	0.0247	0.023
Toxoplasma gondii	peptidase family M13 protein	0.0188	0.0829	1
Echinococcus granulosus	membrane bound transcription factor site 1	0.0086	0.0219	0.0201
Mycobacterium tuberculosis	Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3)	0.0086	0.0219	0.1612
Schistosoma mansoni	furin-1 (S08 family)	0.0873	0.4938	0.4929
Plasmodium vivax	sortilin, putative	0.0068	0.0111	0.1254
Trichomonas vaginalis	cyclins, putative	0.0052	0.0018	0.0033
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0091	0.0247	0.03
Schistosoma mansoni	histamine h1 receptor	0.0091	0.0247	0.023
Echinococcus granulosus	neuropeptides capa receptor	0.0091	0.0247	0.023
Schistosoma mansoni	subfamily S8B non-peptidase homologue (S08 family)	0.0524	0.2841	0.2829
Brugia malayi	Furin-like cysteine rich region family protein	0.0259	0.1254	0.1239
Leishmania major	UDP-galactopyranose mutase	0.0054	0.0031	0.0089
Mycobacterium leprae	PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5)	0.0086	0.0219	0.2355
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0091	0.0247	0.03
Echinococcus granulosus	sex peptide receptor	0.0091	0.0247	0.023
Onchocerca volvulus		0.0091	0.0247	0.1696
Onchocerca volvulus		0.0091	0.0247	0.1696
Onchocerca volvulus		0.0091	0.0247	0.1696
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Echinococcus multilocularis	serotonin receptor	0.0091	0.0247	0.03
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0095	0.0272	0.0255
Brugia malayi	neuropeptide F receptor	0.0091	0.0247	0.023
Brugia malayi	hypothetical protein	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0139	0.0536	0.0519
Onchocerca volvulus		0.0091	0.0247	0.1696
Echinococcus multilocularis	aminopeptidase N	0.0237	0.1125	0.1446
Mycobacterium ulcerans	epoxide hydrolase EphA	0.0161	0.067	0.5481
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0091	0.0247	0.023
Brugia malayi	G protein-coupled receptor	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0931	0.5281	1
Schistosoma mansoni	hypothetical protein	0.0091	0.0247	0.023
Echinococcus granulosus	epidermal growth factor receptor	0.0259	0.1254	0.1239
Echinococcus granulosus	hypothetical protein	0.0091	0.0247	0.023
Brugia malayi	RE15519p	0.0091	0.0247	0.023
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0259	0.1254	0.1239
Onchocerca volvulus		0.0237	0.1125	0.7728
Echinococcus granulosus	Furin 1	0.0524	0.2841	0.2829
Echinococcus granulosus	aminopeptidase N	0.0237	0.1125	0.1109
Trichomonas vaginalis	conserved hypothetical protein	0.0388	0.2032	0.3847
Echinococcus granulosus	neuropeptide receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0091	0.0247	0.023
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0091	0.0247	0.023
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0106	0.0338	0.0321
Brugia malayi	putative neuropeptide receptor	0.0091	0.0247	0.023
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.0135	0.0514	0.0497
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0091	0.0247	0.03
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0219	0.0201
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Schistosoma mansoni	family A2 unassigned peptidase (A02 family)	0.0223	0.1039	0.1023
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Onchocerca volvulus		0.0091	0.0247	0.1696
Brugia malayi	endochitinase	0.0292	0.1456	0.144
Onchocerca volvulus		0.0091	0.0247	0.1696
Entamoeba histolytica	chitinase, putative	0.0292	0.1456	1
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0091	0.0247	0.1696
Trichomonas vaginalis	cyclin B, putative	0.0052	0.0018	0.0033
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0091	0.0247	0.023
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Echinococcus granulosus	G protein coupled receptor 139	0.0091	0.0247	0.023
Echinococcus granulosus	tm gpcr rhodopsin	0.0091	0.0247	0.023
Onchocerca volvulus		0.0052	0.0018	0.0118
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0091	0.0247	0.03
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0086	0.0219	0.0414
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0247	0.023
Mycobacterium ulcerans	membrane-anchored mycosin MycP3	0.0086	0.0219	0.1612
Echinococcus granulosus	neuropeptide s receptor	0.0091	0.0247	0.023
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0091	0.0247	0.023
Loa Loa (eye worm)	hypothetical protein	0.0249	0.1198	0.1182
Mycobacterium ulcerans	membrane-anchored serine protease (mycosin), MycP4	0.0086	0.0219	0.1612
Brugia malayi	neuroendocrine convertase 1 precursor	0.1623	0.9429	0.9428
Leishmania major	aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1	0.007	0.0123	0.073
Trichomonas vaginalis	cyclin B, putative	0.0052	0.0018	0.0033
Schistosoma mansoni	amine oxidase	0.0054	0.0031	0.0013
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0931	0.5281	1
Loa Loa (eye worm)	melatonin receptor type 1A	0.0091	0.0247	0.023

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 883730