Detailed information for compound 88405

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 784.972 | Formula: C44H64O12
  • H donors: 2 H acceptors: 7 LogP: 6.25 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)O[C@H]1C(=O)[C@]2(C)[C@@H](OC(=O)CCC3CCC4C(C3)CCCC4)C[C@@H]3[C@]([C@H]2[C@@H]([C@]2(C(C1=C(C)[C@@H](O)C2)(C)C)O)OC(=O)C1CCCCC1)(CO3)OC(=O)C
  • InChi: 1S/C44H64O12/c1-24-31(47)22-44(51)39(55-40(50)29-13-8-7-9-14-29)37-42(6,38(49)36(53-25(2)45)35(24)41(44,4)5)32(21-33-43(37,23-52-33)56-26(3)46)54-34(48)19-17-27-16-18-28-12-10-11-15-30(28)20-27/h27-33,36-37,39,47,51H,7-23H2,1-6H3/t27?,28?,30?,31-,32-,33+,36+,37-,39-,42+,43-,44+/m0/s1
  • InChiKey: IBQIONGNMRNFST-MADAAADLSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus neuropeptide s receptor 0.0503 0.6944 0.6955
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0006 0.0004 0.0004
Mycobacterium ulcerans beta-lactamase 0.0113 0.15 0.2465
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0009 0.0054 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0343 0.0448
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0318 0.0638
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0029 0.0325 0.0326
Echinococcus multilocularis muscleblind protein 1 0.0043 0.0517 0.0518
Plasmodium vivax nucleoside-diphosphatase mig-23, putative 0.0012 0.009 0.023
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0409 0.0853
Echinococcus granulosus lamin 0.0025 0.0268 0.0268
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0008 0.0028 0.0028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0121 0.0121
Plasmodium vivax multidomain scavenger receptor, putative 0.001 0.0067 0.0066
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Echinococcus granulosus intermediate filament protein 0.0025 0.0268 0.0268
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0041 0.0491 0.1019
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0325 0.0326
Echinococcus granulosus G protein coupled receptor 139 0.0029 0.0325 0.0326
Loa Loa (eye worm) beta-lactamase 0.0113 0.15 0.3205
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0018 0.0177 0.0194
Trichomonas vaginalis adenylate cyclase, putative 0.0009 0.0054 0.0112
Brugia malayi G protein-coupled receptor F59B2.13 0.0029 0.0325 0.0424
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0447 0.0921
Trypanosoma brucei RNA helicase, putative 0.0333 0.4576 1
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0118 0.1575 0.1578
Trichomonas vaginalis reverse transcriptases, putative 0.0008 0.0028 0.0059
Plasmodium falciparum nucleoside-diphosphatase, putative 0.0012 0.009 0.0234
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0186 0.0896
Mycobacterium tuberculosis Probable esterase LipL 0.0113 0.15 0.1476
Echinococcus granulosus FTZ F1 alpha 0.003 0.0343 0.0344
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0029 0.0325 0.0326
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0602 0.0603
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0012 0.0095 0.0067
Echinococcus granulosus dna polymerase eta 0.0018 0.0178 0.0178
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0166 0.0209
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Trypanosoma brucei unspecified product 0.0011 0.0076 0.0106
Loa Loa (eye worm) brix domain-containing protein 0.0025 0.0272 0.0582
Leishmania major nucleoside phosphatase, putative,guanosine diphosphatase, putative 0.0018 0.0177 0.0852
Loa Loa (eye worm) hypothetical protein 0.0013 0.0105 0.0224
Trichomonas vaginalis adenosine diphosphatase, putative 0.0012 0.009 0.0188
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0087 0.04
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Loa Loa (eye worm) CHromoDomain protein family member 0.0006 0.0004 0.0008
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0316 0.1955
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0254 0.053
Loa Loa (eye worm) hypothetical protein 0.003 0.0343 0.0733
Schistosoma mansoni neuropeptide receptor 0.0029 0.0325 0.0326
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0028 0.0315 0.0315
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0325 0.0326
Mycobacterium tuberculosis Probable dehydrogenase 0.0026 0.028 0.0253
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0343 0.0344
Brugia malayi beta-lactamase family protein 0.0113 0.15 0.1958
Schistosoma mansoni aryl hydrocarbon receptor 0.0036 0.0426 0.0427
Echinococcus multilocularis somatostatin receptor 0.0029 0.0325 0.0326
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Onchocerca volvulus 0.0008 0.0028 0.0059
Echinococcus multilocularis cpg binding protein 0.0013 0.0105 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0548 0.1143
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0186 0.1075
Schistosoma mansoni opsin-like receptor 0.0029 0.0325 0.0326
Trypanosoma brucei nucleoside phosphatase, putative 0.0018 0.0177 0.0327
Loa Loa (eye worm) hypothetical protein 0.0113 0.15 0.3205
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0017 0.0166 0.0139
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0017 0.0159 0.0289
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0379 0.2249
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0008 0.0028 0.0028
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0083 0.108 0.1409
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0028 0.0315 0.1805
Schistosoma mansoni intermediate filament proteins 0.0025 0.0268 0.0268
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0316 0.0659
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.039 0.0814
Entamoeba histolytica brix domain containing protein 0.0025 0.0272 0.1977
Schistosoma mansoni inositol monophosphatase 0.0038 0.0454 0.0455
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0454 0.0455
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0032 0.0367 0.0479
Echinococcus multilocularis dro:myosuppressin receptor 0.0029 0.0325 0.0326
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0197 0.1283
Loa Loa (eye worm) hypothetical protein 0.0016 0.0145 0.0309
Loa Loa (eye worm) hypothetical protein 0.0009 0.0046 0.0098
Leishmania major eukaryotic translation initiation factor-like protein 0.0028 0.0315 0.1805
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0121 0.0259
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0343 0.0344
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0227 0.0474
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0197 0.2086
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0343 0.0733
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0076 0.0978 0.8267
Chlamydia trachomatis endonuclease IV 0.0083 0.108 0.1739
Entamoeba histolytica hypothetical protein 0.0037 0.0433 0.3408
Echinococcus multilocularis serotonin receptor 0.0029 0.0325 0.0326
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.0067 0.0067
Brugia malayi hypothetical protein 0.0014 0.0121 0.0158
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0343 0.0344
Brugia malayi cation channel family protein 0.0049 0.0602 0.0786
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0316 0.0659
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0325 0.0326
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0316 0.0659
Loa Loa (eye worm) hypothetical protein 0.001 0.0062 0.0133
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0017 0.0159 0.016
Trypanosoma cruzi metacaspase, putative 0.0045 0.0548 0.353
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0181 0.0181
Toxoplasma gondii hypothetical protein 0.0048 0.0599 0.0911
Schistosoma mansoni caspase-7 (C14 family) 0.0086 0.113 0.1132
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0447 0.0933
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0076 0.0106
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0172 0.08
Echinococcus multilocularis pyruvate kinase 0.0018 0.0172 0.0173
Schistosoma mansoni zinc finger protein 0.0014 0.0121 0.0121
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0017 0.0159 0.0892
Brugia malayi steroid hormone receptor 0.003 0.0343 0.0448
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0325 0.0326
Mycobacterium tuberculosis Probable reductase 0.0026 0.028 0.0253
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0246 0.048
Mycobacterium ulcerans epimerase 0.0022 0.0227 0.0311
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0028 0.0316 0.0659
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0343 0.0344
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Brugia malayi hypothetical protein 0.0029 0.0326 0.0425
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0028 0.0315 0.0657
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0379 0.0771
Echinococcus granulosus apoptotic protease activating factor 1 0.0042 0.0505 0.0506
Mycobacterium leprae conserved hypothetical protein 0.0113 0.15 0.2465
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0341 0.468 1
Brugia malayi hypothetical protein 0.0008 0.0028 0.0037
Brugia malayi hypothetical protein 0.0018 0.0178 0.0232
Loa Loa (eye worm) hypothetical protein 0.0042 0.0505 0.1079
Trypanosoma cruzi ribonuclease H1, putative 0.0016 0.0141 0.0767
Schistosoma mansoni peter pan-related 0.0025 0.0272 0.0273
Echinococcus multilocularis aryl hydrocarbon receptor 0.0009 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0044 0.0536 0.1145
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0035 0.0416 0.3454
Brugia malayi cytoplasmic intermediate filament protein 0.0013 0.0108 0.014
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0197 0.0197
Schistosoma mansoni P2X receptor subunit 0.0039 0.0463 0.0463
Leishmania major DNA polymerase eta, putative 0.0018 0.0178 0.0858
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.009 0.1173 0.2506
Loa Loa (eye worm) hypothetical protein 0.0009 0.0054 0.0115
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0017 0.0166 0.0209
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0325 0.0695
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0029 0.0325 0.0695
Schistosoma mansoni biogenic amine receptor 0.0029 0.0325 0.0326
Echinococcus granulosus caspase 0.0118 0.1575 0.1578
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0017 0.0166 0.0209
Brugia malayi ImpB/MucB/SamB family protein 0.0011 0.0076 0.01
Plasmodium falciparum apyrase, putative 0.0012 0.009 0.0234
Brugia malayi MAP kinase sur-1 0.0015 0.0125 0.0164
Mycobacterium ulcerans DNA polymerase IV 0.0011 0.0076 0.0056
Leishmania major pyruvate kinase 0.0035 0.0409 0.2458
Brugia malayi conserved hypotetical protein 0.0014 0.0121 0.0158
Echinococcus granulosus ryanodine receptor 44f 0.0018 0.0169 0.017
Echinococcus multilocularis expressed protein 0.0033 0.039 0.0391
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.3585 0.7479
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Schistosoma mansoni P2X receptor subunit 0.0039 0.0463 0.0463
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Echinococcus granulosus p2X purinoceptor 4 0.0039 0.0463 0.0463
Mycobacterium tuberculosis Probable lipase LipD 0.0113 0.15 0.1476
Echinococcus granulosus pyruvate kinase 0.0018 0.0172 0.0173
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0029 0.0325 0.0326
Mycobacterium tuberculosis Conserved protein 0.0113 0.15 0.1476
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0432 0.5954 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0015 0.0125 0.0107
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0325 0.0326
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0121 0.0253
Trichomonas vaginalis maltase-glucoamylase, putative 0.0076 0.0978 0.2041
Trypanosoma brucei glycosyl hydrolase-like protein 0.0028 0.0316 0.0633
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0029 0.0325 0.0424
Brugia malayi Cytochrome P450 family protein 0.0012 0.0087 0.0114
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0165 0.0165
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0011 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0121 0.0158
Brugia malayi RNase H family protein 0.0016 0.0141 0.0184
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0454 0.0937
Mycobacterium leprae Possible regulatory protein 0.0009 0.0054 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0076 0.0106
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0017 0.0159 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0548 0.1143
Echinococcus granulosus peptide allatostatin:somatostatin 0.0029 0.0325 0.0326
Brugia malayi hypothetical protein 0.0029 0.0325 0.0424
Onchocerca volvulus 0.003 0.0343 0.0716
Toxoplasma gondii exonuclease III APE 0.0019 0.0186 0.0211
Brugia malayi putative neuropeptide receptor NPR1 0.0029 0.0325 0.0424
Echinococcus granulosus somatostatin receptor 0.0029 0.0325 0.0326
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0781 0.0782
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Schistosoma mansoni neuropeptide receptor 0.0029 0.0325 0.0326
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0325 0.0326
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.15 0.313
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0325 0.0326
Echinococcus multilocularis neuropeptide receptor A26 0.0503 0.6944 0.6955
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0343 0.0344
Trichomonas vaginalis esterase, putative 0.0113 0.15 0.313
Echinococcus granulosus ribonuclease H1 0.0016 0.0141 0.0141
Echinococcus granulosus raf serine:threonine protein kinase 0.0019 0.0181 0.0181
Echinococcus multilocularis p2X purinoceptor 4 0.0039 0.0463 0.0463
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0042 0.0514 0.0514
Brugia malayi reverse transcriptase 0.0008 0.0028 0.0037
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0307 0.4202 0.8979
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0409 0.0853
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0065 0.0836 0.0837
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.009 0.0188
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0172 0.0187
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0197 0.0256
Trypanosoma brucei ingi protein (ORF1) 0.0023 0.0246 0.048
Trichomonas vaginalis ferritin, putative 0.0009 0.0043 0.009
Echinococcus granulosus mitogen activated protein kinase 3 0.0015 0.0125 0.0126
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.0003
Trypanosoma cruzi metacaspase, putative 0.0045 0.0548 0.353
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0166 0.0209
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0325 0.0326
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.15 0.313
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0186 0.0389
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0009 0.0043 0.0043
Schistosoma mansoni alpha-glucosidase 0.0293 0.4018 0.4024
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0028 0.0313 0.0313
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0015 0.0136 0.029
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0168 0.227 0.2249
Loa Loa (eye worm) intermediate filament protein 0.0025 0.0268 0.0572
Leishmania major metacaspase, putative 0.0045 0.0548 0.3416
Brugia malayi hypothetical protein 0.0029 0.0325 0.0424
Schistosoma mansoni amine GPCR 0.0029 0.0325 0.0326
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0113 0.15 0.3205
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0008 0.0028 0.0028
Brugia malayi hypothetical protein 0.0016 0.0145 0.0189
Trichomonas vaginalis DNA polymerase eta, putative 0.0011 0.0076 0.0159
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0325 0.0326
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0076 0.0978 0.2041
Loa Loa (eye worm) pyruvate kinase 0.0007 0.0025 0.0054
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0121 0.0121
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0027 0.0298 0.0593
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0398 0.0601
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0432 0.5954 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0029 0.0325 0.0326
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0029 0.0325 0.0424
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0009 0.005 0.005
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0409 0.0619
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0343 0.0344
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0009 0.005 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0325 0.0326
Onchocerca volvulus 0.0029 0.0325 0.0678
Echinococcus granulosus g protein coupled receptor 0.0029 0.0325 0.0326
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0325 0.0695
Loa Loa (eye worm) ryanodine receptor 0.0009 0.0043 0.0091
Loa Loa (eye worm) hypothetical protein 0.0024 0.0262 0.0559
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Echinococcus granulosus aryl hydrocarbon receptor 0.0009 0.0054 0.0054
Schistosoma mansoni neuropeptide receptor 0.0029 0.0325 0.0326
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0325 0.0326
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.009 0.1173 1
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0028 0.0315 0.063
Mycobacterium tuberculosis Probable hydrolase 0.0113 0.15 0.1476
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0343 0.0344
Schistosoma mansoni adenoreceptor 0.0029 0.0325 0.0326
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0012 0.009 0.0188
Loa Loa (eye worm) hypothetical protein 0.0045 0.0548 0.117
Brugia malayi reverse transcriptase 0.0008 0.0028 0.0037
Echinococcus multilocularis peter pan 0.0025 0.0272 0.0273
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0121 0.0121
Echinococcus granulosus RUN 0.001 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0009 0.005 0.0107
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0121 0.0121
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0409 0.0838
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0186 0.0918
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0065 0.0081
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0325 0.0326
Echinococcus multilocularis zinc finger protein 0.002 0.0209 0.0209
Echinococcus granulosus neuropeptide receptor 0.0029 0.0325 0.0326
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0028 0.0315 0.0657
Leishmania major alpha glucosidase II subunit, putative 0.0076 0.0978 0.6394
Trichomonas vaginalis ssf, putative 0.0025 0.0272 0.0568
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0145 0.0145
Trypanosoma cruzi nucleoside phosphatase, putative 0.0018 0.0177 0.101
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0781 0.0782
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0028 0.0316 0.2366
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0186 0.1212
Brugia malayi ecdysteroid receptor 0.003 0.0343 0.0448
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0012 0.0092 0.0432
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0447 0.2846
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0548 0.0824
Loa Loa (eye worm) hypothetical protein 0.0026 0.0284 0.0608
Mycobacterium ulcerans hypothetical protein 0.0017 0.0166 0.0209
Trypanosoma brucei metacaspase MCA2 0.0045 0.0548 0.1143
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0065 0.0836 0.0837
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0029 0.0325 0.0424
Brugia malayi RNase H family protein 0.0016 0.0141 0.0184
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0029 0.0325 0.0326
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Leishmania major 4-coumarate:coa ligase-like protein 0.0017 0.0166 0.0779
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0318 0.2484
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0379 0.2383
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0186 0.0187
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0013 0.0105 0.0087
Trypanosoma cruzi trypanothione reductase, putative 0.0011 0.0079 0.0349
Leishmania major protein kinase, putative 0.001 0.0055 0.0013
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0065 0.0004
Onchocerca volvulus Neuropeptide F receptor homolog 0.0029 0.0325 0.0678
Toxoplasma gondii Nucleoside-diphosphatase 0.0012 0.009 0.0047
Leishmania major 4-coumarate:coa ligase-like protein 0.0017 0.0166 0.0779
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0113 0.15 0.1476
Loa Loa (eye worm) hypothetical protein 0.0016 0.0145 0.0309
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0548 0.1143
Brugia malayi hypothetical protein 0.0016 0.0145 0.0189
Loa Loa (eye worm) TYRA-2 protein 0.0029 0.0325 0.0695
Brugia malayi sulfakinin receptor protein 0.0029 0.0325 0.0424
Plasmodium falciparum thioredoxin reductase 0.0011 0.0079 0.0128
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0325 0.0326
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0121 0.0253
Onchocerca volvulus 0.0017 0.0166 0.0347
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0548 0.0824
Toxoplasma gondii hypothetical protein 0.0017 0.0159 0.0165
Brugia malayi PHD-finger family protein 0.0026 0.0284 0.0371
Loa Loa (eye worm) hypothetical protein 0.0016 0.0145 0.0309
Echinococcus multilocularis caspase 3 0.0074 0.095 0.0952
Echinococcus multilocularis beta LACTamase domain containing family member 0.0113 0.15 0.1502
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0343 0.0344
Onchocerca volvulus 0.0029 0.0325 0.0678
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0186 0.1075
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0343 0.0448
Onchocerca volvulus 0.0029 0.0325 0.0678
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0166 0.0209
Brugia malayi Glycosyl hydrolases family 31 protein 0.0028 0.0316 0.0412
Plasmodium vivax glutathione reductase, putative 0.0011 0.0079 0.0156
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0409 0.0874
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0015 0.0125 0.0661
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0009 0.0043 0.0015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.1305 0.1307
Schistosoma mansoni opsin-like receptor 0.0029 0.0325 0.0326
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.0072 0.0926 0.1977
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0029 0.0325 0.0326
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0121 0.0259
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0028 0.0315 0.0657
Brugia malayi Cytochrome P450 family protein 0.0012 0.0087 0.0114
Echinococcus multilocularis survival motor neuron protein 1 0.0067 0.0864 0.0865
Leishmania major 4-coumarate:coa ligase-like protein 0.0017 0.0166 0.0779
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0054 0.0112
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0254 0.1534
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0087 0.0186
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0008 0.0028 0.0028
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0012 0.0092 0.014
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0017 0.0159 0.0208
Loa Loa (eye worm) hypothetical protein 0.0013 0.0105 0.0224
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0262 0.3585 0.7659
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0029 0.0325 0.0326
Trypanosoma brucei hypothetical protein, conserved 0.0113 0.15 0.3237
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0026 0.028 0.0281
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0121 0.0158
Echinococcus multilocularis transcription factor Dp 1 0.0052 0.0646 0.0647
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0026 0.0282 0.1561
Trichomonas vaginalis adenosine diphosphatase, putative 0.0012 0.009 0.0188
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0379 0.2383
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0009 0.005 0.0107
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0227 0.0311
Brugia malayi hypothetical protein 0.0121 0.1612 0.2104
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0029 0.0325 0.0326
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0121 0.0121
Echinococcus granulosus neuropeptide receptor 0.0029 0.0325 0.0326
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.001 0.0055 0.0185
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0072 0.0016
Toxoplasma gondii thioredoxin reductase 0.0011 0.0079 0.0029
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0343 0.0344
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Brugia malayi Glycosyl hydrolases family 31 protein 0.0076 0.0978 0.1277
Trypanosoma brucei metacaspase 0.0045 0.0548 0.1143
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0454 0.0696
Echinococcus multilocularis neuropeptide s receptor 0.0503 0.6944 0.6955
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0076 0.0978 0.1555
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0343 0.0344
Schistosoma mansoni hypothetical protein 0.0013 0.01 0.01
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0017 0.0159 0.0731
Schistosoma mansoni hypothetical protein 0.0029 0.0325 0.0326
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0343 0.0716
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0447 0.3534
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.108 0.7086
Loa Loa (eye worm) hypothetical protein 0.003 0.034 0.0726
Onchocerca volvulus 0.0029 0.0325 0.0678
Echinococcus granulosus expressed protein 0.0009 0.0043 0.0043
Brugia malayi Thioredoxin reductase 0.0011 0.0079 0.0104
Brugia malayi M-phase phosphoprotein, mpp8 0.0029 0.0326 0.0425
Echinococcus granulosus muscleblind protein 0.0043 0.0517 0.0518
Brugia malayi Bromodomain containing protein 0.0039 0.0466 0.0608
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0325 0.0326
Echinococcus multilocularis caspase 8 0.0045 0.0548 0.0549
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0145 0.0145
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0009 0.005 0.005
Onchocerca volvulus 0.0029 0.0325 0.0678
Onchocerca volvulus 0.0197 0.2674 0.558
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0548 0.1143
Trichomonas vaginalis adenosine diphosphatase, putative 0.0012 0.009 0.0188
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0254 0.1814
Mycobacterium ulcerans putative regulatory protein 0.0027 0.0295 0.0427
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0017 0.0166 0.0209
Schistosoma mansoni lamin 0.0025 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Brugia malayi nuclear receptor NHR-88 0.0014 0.0121 0.0158
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0343 0.0344
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0017 0.0166 0.0209
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0343 0.0344
Echinococcus multilocularis microtubule associated protein 2 0.0721 0.9984 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0325 0.0326
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0173 0.037
Brugia malayi hypothetical protein 0.0029 0.0325 0.0424
Loa Loa (eye worm) hypothetical protein 0.0113 0.15 0.3205
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.3585 0.7479
Echinococcus multilocularis apoptotic protease activating factor 1 0.0042 0.0505 0.0506
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Loa Loa (eye worm) DR-78 0.0014 0.0121 0.0259
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0325 0.0326
Mycobacterium ulcerans hypothetical protein 0.0045 0.0556 0.0868
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0325 0.0326
Schistosoma mansoni cpg binding protein 0.0013 0.0105 0.0106
Loa Loa (eye worm) hypothetical protein 0.003 0.0343 0.0733
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Loa Loa (eye worm) hypothetical protein 0.0017 0.0166 0.0355
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0011 0.0076 0.0157
Onchocerca volvulus 0.0029 0.0325 0.0678
Trichomonas vaginalis adenosine diphosphatase, putative 0.0012 0.009 0.0188
Echinococcus granulosus caspase 3 0.0074 0.095 0.0952
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0012 0.0092 0.0432
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0017 0.0159 0.016
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0029 0.0325 0.0326
Trichomonas vaginalis CMGC family protein kinase 0.0015 0.0125 0.0262
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.039 0.0833
Echinococcus granulosus bloom syndrome protein 0.0039 0.0474 0.0475
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0026 0.028 0.0402
Echinococcus granulosus fmrfamide receptor 0.0029 0.0325 0.0326
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0009 0.005 0.0105
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0017 0.0166 0.0217
Schistosoma mansoni rab6-interacting 0.001 0.0067 0.0067
Brugia malayi translation initiation factor 4E 0.0028 0.0315 0.0411
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.2455 0.5121
Trypanosoma brucei DNA polymerase IV, putative 0.0011 0.0076 0.0106
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0029 0.0325 0.0424
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0009 0.005 0.0107
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0065 0.0077
Echinococcus granulosus beta LACTamase domain containing family member 0.0113 0.15 0.1502
Echinococcus granulosus g protein coupled receptor 0.0029 0.0325 0.0326
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0029 0.0325 0.0326
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0017 0.0166 0.0209
Brugia malayi AMP-binding enzyme family protein 0.0017 0.0166 0.0217
Trypanosoma cruzi DNA polymerase eta, putative 0.0011 0.0072 0.0296
Mycobacterium ulcerans lipase LipD 0.0113 0.15 0.2465
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0087 0.0186
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0325 0.0326
Schistosoma mansoni blooms syndrome DNA helicase 0.0029 0.0334 0.0335
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0778 0.0779
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0015 0.0129 0.0683
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0447 0.272
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0028 0.0315 0.0428
Schistosoma mansoni cpg binding protein 0.0013 0.0105 0.0106
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0325 0.0326
Brugia malayi nuclear hormone receptor 0.003 0.0343 0.0448
Schistosoma mansoni ferritin 0.0009 0.0043 0.0043
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0009 0.005 0.005
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0433 0.0434
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0325 0.0326
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0262 0.1885
Brugia malayi hypothetical protein 0.0029 0.0325 0.0424
Echinococcus granulosus 3'partial|ectonucleoside triphosphate diphosphohydrolase 0.0012 0.009 0.009
Echinococcus granulosus serotonin receptor 0.0029 0.0325 0.0326
Echinococcus multilocularis neuropeptide FF receptor 2 0.0029 0.0325 0.0326
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0343 0.0448
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0015 0.0125 0.0661
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0325 0.0326
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0076 0.0978 0.2041
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0325 0.0326
Loa Loa (eye worm) hypothetical protein 0.003 0.0343 0.0733
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Schistosoma mansoni thyroid hormone receptor 0.003 0.0343 0.0344
Onchocerca volvulus 0.0029 0.0325 0.0678
Echinococcus granulosus KRAB A domain containing protein 0.0008 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Onchocerca volvulus 0.0029 0.0325 0.0678
Trypanosoma brucei ribonuclease H1 0.0016 0.0141 0.0248
Schistosoma mansoni terminal deoxycytidyl transferase 0.0011 0.0076 0.0076
Brugia malayi nuclear receptor NHR-67 0.0014 0.0121 0.0158
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0316 0.0659
Trypanosoma brucei DNA polymerase IV, putative 0.0011 0.0076 0.0106
Echinococcus granulosus Polycystic kidney disease protein 0.001 0.0067 0.0067
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0028 0.032 0.0293
Echinococcus multilocularis expressed protein 0.0009 0.0043 0.0043
Echinococcus multilocularis pyruvate kinase 0.0018 0.0172 0.0173
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0047 0.0575 0.0576
Plasmodium vivax SET domain protein, putative 0.0044 0.0539 0.3342
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Loa Loa (eye worm) glutathione reductase 0.0011 0.0079 0.017
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0343 0.0344
Trypanosoma cruzi metacaspase 5, putative 0.0045 0.0548 0.353
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0159 0.0892
Onchocerca volvulus 0.0029 0.0326 0.068
Brugia malayi hypothetical protein 0.0029 0.0325 0.0424
Schistosoma mansoni lamin 0.0025 0.0268 0.0268
Echinococcus granulosus pyruvate kinase 0.0018 0.0172 0.0173
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0118 0.1575 0.1578
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0186 0.1959
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0121 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0548 0.1143
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0325 0.0326
Leishmania major peter pan protein, putative 0.0025 0.0272 0.1512
Onchocerca volvulus 0.0025 0.0268 0.0559
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2325 0.4852
Brugia malayi Serotonin receptor 0.0029 0.0325 0.0424
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0778 0.0779
Echinococcus multilocularis mitogen activated protein kinase 0.0015 0.0125 0.0126
Entamoeba histolytica hypothetical protein 0.0037 0.0433 0.3408
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0409 0.0382
Echinococcus multilocularis mitogen activated protein kinase 3 0.0015 0.0125 0.0126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0343 0.0733
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0409 0.2588
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0343 0.0733
Loa Loa (eye worm) hypothetical protein 0.003 0.0347 0.0742
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.009 0.0188
Entamoeba histolytica acyl-CoA synthetase, putative 0.0017 0.0166 0.1034
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0076 0.0978 0.2091
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0076 0.0106
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.15 0.1502
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0009 0.0054 0.0112
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0009 0.0054 0.0054
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0001 0.0003
Plasmodium falciparum glutathione reductase 0.0011 0.0079 0.0128
Echinococcus granulosus caspase 8 0.0045 0.0548 0.0549
Trypanosoma brucei ISWI complex protein 0.0016 0.014 0.0245
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0316 0.0659
Mycobacterium tuberculosis Probable oxidoreductase 0.0028 0.032 0.0293
Leishmania major hypothetical protein, conserved 0.0016 0.014 0.0595
Schistosoma mansoni rab6-interacting 0.001 0.0067 0.0067
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0262 0.056
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0009 0.005 0.005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0447 0.0933
Loa Loa (eye worm) inositol-1 0.0038 0.0454 0.097
Echinococcus multilocularis tumor protein p63 0.0333 0.4564 0.4571
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0009 0.005 0.005
Onchocerca volvulus 0.0029 0.0325 0.0678
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0012 0.0087 0.0075
Brugia malayi Bloom's syndrome protein homolog 0.0039 0.0474 0.0618
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0343 0.0448
Trichomonas vaginalis DNA helicase recq, putative 0.0039 0.0474 0.0989
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0343 0.0448
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0343 0.0733
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0343 0.0344
Schistosoma mansoni alpha-glucosidase 0.0293 0.4018 0.4024
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0087 0.04
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0009 0.0054 0.0112
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0168 0.227 0.3768
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0083 0.108 0.1754
Schistosoma mansoni amine GPCR 0.0029 0.0325 0.0326
Brugia malayi Raf kinase 0.0019 0.0181 0.0236
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0186 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0227 0.0485
Schistosoma mansoni hypothetical protein 0.0359 0.4938 0.4946
Trichomonas vaginalis reverse transcriptases, putative 0.0008 0.0028 0.0059
Brugia malayi Zinc knuckle family protein 0.0008 0.0028 0.0037
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0083 0.108 0.1054
Schistosoma mansoni pyruvate kinase 0.0035 0.0409 0.041
Loa Loa (eye worm) hypothetical protein 0.0083 0.108 0.2307
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0454 0.0947
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0781 0.0782
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0325 0.0326
Schistosoma mansoni hypothetical protein 0.0037 0.0433 0.0434
Mycobacterium ulcerans hypothetical protein 0.0113 0.15 0.2465
Trypanosoma cruzi DNA polymerase eta, putative 0.0018 0.0178 0.1016
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0065 0.0249
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Schistosoma mansoni caspase-3 (C14 family) 0.0118 0.1575 0.1578
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0343 0.0448
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0447 0.0448
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0548 0.1143
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0012 0.009 0.0188
Trypanosoma cruzi metacaspase 5, putative 0.0045 0.0548 0.353
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0076 0.0106
Leishmania major hypothetical protein, conserved 0.0018 0.0178 0.0857
Echinococcus multilocularis RUN 0.001 0.0067 0.0067
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.009 0.1173 0.1175
Brugia malayi neuropeptide F receptor 0.0029 0.0325 0.0424
Echinococcus granulosus p2X purinoceptor 4 0.0039 0.0463 0.0463
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0318 0.197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0029 0.0325 0.0326
Schistosoma mansoni ryanodine receptor related 0.0032 0.0367 0.0368
Echinococcus multilocularis pyruvate kinase 0.0028 0.0307 0.0307
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0076 0.0106
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0325 0.0326
Schistosoma mansoni biogenic amine receptor 0.0029 0.0325 0.0326
Leishmania major ATP diphosphohydrolase 0.0018 0.0177 0.0852
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0009 0.005 0.0105
Mycobacterium ulcerans hypothetical protein 0.0022 0.0227 0.0311
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0008 0.0028 0.0028
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0017 0.0166 0.0355
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0026 0.028 0.0253
Schistosoma mansoni lipoxygenase 0.0047 0.0575 0.0576
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0166 0.0209
Trichomonas vaginalis reverse transcriptase [C. elegans], putative 0.0008 0.0028 0.0059
Echinococcus granulosus caspase 2 0.0086 0.113 0.1132
Trichomonas vaginalis DNA helicase recq1, putative 0.0039 0.0474 0.0989
Loa Loa (eye worm) hypothetical protein 0.0086 0.113 0.2414
Echinococcus granulosus single minded 2 0.0027 0.0295 0.0296
Trypanosoma cruzi metacaspase, putative 0.0045 0.0548 0.353
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0409 0.0589
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0012 0.0095 0.0067
Loa Loa (eye worm) hypothetical protein 0.0113 0.15 0.3205
Schistosoma mansoni nuclear receptor 0.0014 0.0121 0.0121
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0343 0.0716
Brugia malayi ecdysone receptor 0.0014 0.0121 0.0158
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0029 0.0325 0.0326
Schistosoma mansoni zinc finger protein 0.002 0.0209 0.0209
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0121 0.0121
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0113 0.15 0.2465
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.108 1
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0065 0.0836 0.1743
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0264 0.3606 0.6028
Brugia malayi Cytochrome P450 family protein 0.0022 0.0224 0.0293
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0121 0.0121
Schistosoma mansoni hypothetical protein 0.0029 0.0325 0.0326
Echinococcus multilocularis serotonin receptor 0.0029 0.0325 0.0326
Brugia malayi hypothetical protein 0.001 0.0067 0.0087
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Chlamydia trachomatis pyruvate kinase 0.0035 0.0409 0.0602
Schistosoma mansoni protein kinase 0.0008 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0011 0.0083 0.0177
Brugia malayi AMP-binding enzyme family protein 0.0017 0.0166 0.0217
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.009 0.1173 0.2517
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0008 0.0028 0.0028
Brugia malayi reverse transcriptase 0.0008 0.0028 0.0037
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0008 0.0028 0.0028
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.009 0.1173 0.7739
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0009 0.0054 0.0112
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0145 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0447 0.0933
Brugia malayi Muscleblind-like protein 0.0043 0.0517 0.0675
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0433 0.0434
Schistosoma mansoni P2X receptor subunit 0.0039 0.0463 0.0463
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.15 0.313
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0017 0.0166 0.0209
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0012 0.0089 0.0089
Brugia malayi Dopamine receptor protein 2 0.0029 0.0325 0.0424
Schistosoma mansoni hypothetical protein 0.0359 0.4938 0.4946
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0343 0.0344
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0197 0.0228
Brugia malayi Serotonin receptor 0.0029 0.0325 0.0424
Echinococcus granulosus 7TM GPCR rhodopsin 0.0029 0.0325 0.0326
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0008 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0009 0.005 0.0107
Schistosoma mansoni guanosine-diphosphatase 0.0012 0.009 0.009
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.001 0.0055 0.0185
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0008 0.0028 0.0028
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0013 0.0105 0.0077
Echinococcus multilocularis bloom syndrome protein 0.0039 0.0474 0.0475
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0012 0.009 0.009
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0145 0.0309
Giardia lamblia Ribonuclease H 0.0016 0.0141 0.1398
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0343 0.0448
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0325 0.0326
Trypanosoma cruzi metacaspase, putative 0.0045 0.0548 0.353
Toxoplasma gondii endonuclease IV APN 0.0083 0.108 0.1727
Schistosoma mansoni growth hormone secretagogue receptor 0.0029 0.0325 0.0326
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0325 0.0695
Onchocerca volvulus Peter pan protein homolog 0.0025 0.0272 0.0568
Echinococcus granulosus 7tm_1 domain containing protein 0.0029 0.0325 0.0326
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0076 0.0978 0.8267
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0029 0.0325 0.0326
Brugia malayi Glycosyl hydrolases family 31 protein 0.0341 0.468 0.6108
Loa Loa (eye worm) hypothetical protein 0.0025 0.0268 0.0572
Echinococcus granulosus zinc finger protein 0.002 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Onchocerca volvulus 0.0007 0.0025 0.0052
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0318 0.197
Echinococcus granulosus g-protein coupled receptor 0.0029 0.0325 0.0326
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0325 0.0326
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0012 0.0092 0.0432
Loa Loa (eye worm) hypothetical protein 0.0121 0.1612 0.3444
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0062 0.0062
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0231 0.3151 0.6733
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0009 0.0054 0.0173
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0008 0.0028 0.0028
Schistosoma mansoni loxhd1 0.001 0.0067 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0343 0.0448
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0009 0.005 0.005
Echinococcus granulosus p2X purinoceptor 4 0.0039 0.0463 0.0463
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0009 0.005 0.0105
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2325 0.4852
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.0268 0.035
Schistosoma mansoni hypothetical protein 0.0029 0.0325 0.0326
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.3585 0.7479
Echinococcus multilocularis pyruvate kinase 0.0035 0.0409 0.041
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.001 0.0055 0.0185
Leishmania major hypothetical protein, conserved 0.0113 0.15 1
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0009 0.005 0.005
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0008 0.0028 0.0059
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0454 0.3597
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0186 0.0243
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0015 0.0125 0.0268
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0065 0.0836 0.5395
Echinococcus multilocularis thioredoxin glutathione reductase 0.0011 0.0079 0.008
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0254 0.1385
Loa Loa (eye worm) hypothetical protein 0.0035 0.0409 0.0874
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.1305 0.1307
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0029 0.0325 0.0678
Schistosoma mansoni P2X receptor subunit 0.0039 0.0463 0.0463
Schistosoma mansoni hypothetical protein 0.0042 0.0505 0.0506
Schistosoma mansoni zinc finger protein 0.0016 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0065 0.0836 0.1785
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0318 0.0434
Onchocerca volvulus 0.0029 0.0325 0.0678
Onchocerca volvulus 0.0029 0.0325 0.0678
Echinococcus multilocularis caspase 0.0118 0.1575 0.1578
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0325 0.0326
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0325 0.0326
Brugia malayi Doublecortin family protein 0.001 0.0067 0.0087
Schistosoma mansoni pyruvate kinase 0.0018 0.0172 0.0173
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0001 0.0003
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0017 0.0159 0.0972
Schistosoma mansoni myosin xvIII 0.0029 0.0325 0.0326
Trypanosoma cruzi DNA polymerase kappa, putative 0.0011 0.0076 0.0327
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0548 0.1143
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0325 0.0326
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0015 0.0125 0.0661
Schistosoma mansoni ferritin 0.0009 0.0043 0.0043
Schistosoma mansoni 3-dehydroquinate synthase 0.0168 0.227 0.2274
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0011 0.0076 0.0076
Schistosoma mansoni adenosine diphosphatase 0.0018 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0062 0.0781 0.1669
Echinococcus multilocularis allatostatin A receptor 0.0029 0.0325 0.0326
Leishmania major DNA polymerase eta, putative 0.0011 0.0072 0.0126
Brugia malayi PAS domain containing protein 0.0036 0.0426 0.0556
Plasmodium falciparum acyl-CoA synthetase 0.0013 0.0105 0.0377
Brugia malayi Inositol-1 0.0038 0.0454 0.0593
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0121 0.0259
Trichomonas vaginalis rotamase, putative 0.0033 0.0379 0.0791
Trypanosoma brucei Metacaspase-4 0.0045 0.0548 0.1143
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0013 0.0108 0.023
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0065 0.0836 0.0837
Brugia malayi hypothetical protein 0.0029 0.0325 0.0424
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.01 0.01
Loa Loa (eye worm) RecQ helicase 0.0039 0.0474 0.1012
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0048 0.0599 0.125
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Echinococcus multilocularis muscleblind protein 0.0043 0.0517 0.0518
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0026 0.0284 0.0285
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0045 0.0548 0.0549
Brugia malayi nuclear hormone receptor 0.0014 0.0121 0.0158
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.1305 0.1307
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0186 0.0243
Brugia malayi Zinc knuckle family protein 0.0008 0.0028 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0325 0.0326
Toxoplasma gondii NTPase II 0.0012 0.009 0.0047
Echinococcus multilocularis musashi 0.0025 0.0268 0.0268
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0343 0.0344
Schistosoma mansoni coup transcription factor 0.003 0.0343 0.0344
Brugia malayi nuclear receptor NHR-88 0.003 0.0343 0.0448
Brugia malayi G-protein coupled receptor 0.0029 0.0325 0.0424
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0277 0.0364
Schistosoma mansoni nuclear hormone receptor 0.003 0.0343 0.0344
Onchocerca volvulus 0.0011 0.007 0.0146
Schistosoma mansoni microtubule-associated protein tau 0.0721 0.9984 1
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.0012 0.009 0.009
Echinococcus granulosus geminin 0.0359 0.4938 0.4946
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.0031 0.0356 0.076
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0012 0.0095 0.0067
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0145 0.0145
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.001 0.0065 0.0061
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0012 0.009 0.0047
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.009 0.1173 0.7778
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0017 0.0159 0.0341
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.0012 0.009 0.009
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0017 0.0159 0.016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0548 0.1143
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0168 0.227 0.2249
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0325 0.0695
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0028 0.0315 0.0657
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0029 0.0325 0.0326
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0065 0.0836 0.6994
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0168 0.227 0.3768
Schistosoma mansoni polycystin 1-related 0.001 0.0067 0.0067
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0197 0.042
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.3585 0.7479
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0325 0.0326
Giardia lamblia DINP protein human, muc B family 0.0011 0.0076 0.0597
Trypanosoma brucei DNA polymerase IV, putative 0.0011 0.0076 0.0106
Echinococcus multilocularis RNA directed DNA polymerase 0.0008 0.0028 0.0028
Onchocerca volvulus 0.0014 0.0121 0.0253
Echinococcus multilocularis dna polymerase eta 0.0018 0.0178 0.0178
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0029 0.0325 0.0695
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0257 0.0258
Echinococcus multilocularis ferritin 0.0009 0.0043 0.0043
Schistosoma mansoni ferritin 0.0009 0.0043 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0325 0.0326
Plasmodium vivax hypothetical protein, conserved 0.0113 0.15 1
Trypanosoma brucei metacaspase 5, putative 0.0045 0.0548 0.1143
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0262 0.3585 0.4678
Leishmania major glycosyl hydrolase-like protein 0.0028 0.0316 0.1814
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0548 0.1143
Schistosoma mansoni alpha glucosidase 0.0076 0.0978 0.098
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0013 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.001 0.0067 0.0142
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0012 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Trichomonas vaginalis guanylate cyclase, putative 0.0009 0.0054 0.0112
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.0003
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0017 0.0159 0.0289
Onchocerca volvulus 0.0017 0.0159 0.0333
Loa Loa (eye worm) hypothetical protein 0.0023 0.0241 0.0514
Brugia malayi putative neuropeptide receptor 0.0029 0.0325 0.0424
Leishmania major mitochondrial DNA polymerase beta 0.0086 0.1124 0.7403
Trypanosoma brucei nucleoside diphosphatase, putative 0.0018 0.0177 0.0327
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0159 0.0289
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Echinococcus multilocularis ryanodine receptor 44f 0.0023 0.0241 0.0241
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0076 0.0106
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0026 0.028 0.0281
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0409 0.0838
Loa Loa (eye worm) hypothetical protein 0.0013 0.0105 0.0224
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0325 0.0326
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2325 0.4852
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0121 0.0121
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0539 0.054
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.15 0.313
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0978 0.2041
Echinococcus granulosus thioredoxin glutathione reductase 0.0011 0.0079 0.008
Schistosoma mansoni hypothetical protein 0.0016 0.014 0.014
Mycobacterium tuberculosis Probable lipase LipE 0.0113 0.15 0.1476
Leishmania major ribonuclease H1, putative 0.0016 0.0141 0.0604
Echinococcus granulosus dro:myosuppressin receptor 0.0029 0.0325 0.0326
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0017 0.0159 0.0289
Echinococcus multilocularis transfer RNA-Lys 0.0027 0.0295 0.0296
Entamoeba histolytica acyl-CoA synthetase, putative 0.0017 0.0166 0.1034
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0012 0.009 0.009
Schistosoma mansoni histamine h1 receptor 0.0029 0.0325 0.0326
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0186 0.0402
Trypanosoma brucei DNA polymerase kappa, putative 0.0008 0.0029 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0083 0.0177
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0011 0.0076 0.0163
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0325 0.0326
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.001 0.0055 0.0185
Brugia malayi hypothetical protein 0.0042 0.0505 0.0659
Entamoeba histolytica hypothetical protein 0.0037 0.0433 0.3408
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0029 0.0325 0.0695
Trypanosoma cruzi DNA polymerase kappa, putative 0.0011 0.0076 0.0327
Mycobacterium tuberculosis Conserved hypothetical protein 0.0011 0.0076 0.0048
Plasmodium falciparum BRIX domain, putative 0.0025 0.0272 0.2031
Onchocerca volvulus 0.0349 0.4793 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0447 0.0448
Trypanosoma brucei ingi protein (ORF1) 0.0023 0.0246 0.048
Onchocerca volvulus 0.0014 0.0121 0.0253
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0026 0.028 0.0253
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0015 0.0125 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0548 0.1143
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0447 0.0448
Schistosoma mansoni hypothetical protein 0.0014 0.0115 0.0115
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0325 0.0326
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0447 0.0448
Echinococcus granulosus survival motor neuron protein 1 0.0067 0.0864 0.0865
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0186 0.1182
Trichomonas vaginalis CMGC family protein kinase 0.0015 0.0125 0.0262
Brugia malayi hypothetical protein 0.0067 0.0864 0.1127
Brugia malayi hypothetical protein 0.001 0.0067 0.0087
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0029 0.0325 0.0326
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0272 0.1492
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0548 0.3401
Loa Loa (eye worm) hypothetical protein 0.0039 0.0467 0.0997
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0026 0.028 0.0253
Trichomonas vaginalis CMGC family protein kinase 0.0015 0.0125 0.0262
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0028 0.0315 0.1947
Brugia malayi CHD4 protein 0.0006 0.0004 0.0005
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0318 0.2484
Echinococcus granulosus tachykinin peptides receptor 99D 0.0029 0.0325 0.0326
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Brugia malayi Nucleoside-diphosphatase mig-23 0.0012 0.009 0.0118
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0076 0.0106
Brugia malayi pyruvate kinase 0.0007 0.0025 0.0033
Echinococcus granulosus mitogen activated protein kinase 0.0015 0.0125 0.0126
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0009 0.0043 0.0015
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0008 0.0028 0.0028
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0548 0.1143
Leishmania major protein kinase, putative 0.001 0.0055 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0015 0.0125 0.0262
Brugia malayi ORL1-like opioid receptor 0.0029 0.0325 0.0424
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.0067 0.0067
Loa Loa (eye worm) melatonin receptor type 1A 0.0029 0.0325 0.0695
Echinococcus multilocularis pyruvate kinase 0.0035 0.0409 0.041
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0009 0.0054 0.0054
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0028 0.0315 0.0315
Giardia lamblia Peter pan protein 0.0025 0.0272 0.3023
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.039 0.0509
Trypanosoma cruzi ISWI complex protein 0.0016 0.014 0.0758
Onchocerca volvulus Cell death protein 3 homolog 0.0086 0.113 0.2357
Trichomonas vaginalis rotamase, putative 0.0033 0.039 0.0814
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0454 0.0455
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.3585 0.7479
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0172 0.1044
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0017 0.0166 0.078
Trichomonas vaginalis adenosine/guanosine diphosphatase, putative 0.0012 0.009 0.0188
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0113 0.15 0.1476
Loa Loa (eye worm) hypothetical protein 0.0029 0.0326 0.0696
Echinococcus granulosus hypothetical protein 0.0029 0.0325 0.0326
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0409 0.0874
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.0067 0.0067
Onchocerca volvulus Ribonuclease H1 homolog 0.0016 0.0141 0.0294
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0065 0.0249
Plasmodium falciparum pyruvate kinase 0.0035 0.0409 0.3381
Brugia malayi Pre-SET motif family protein 0.0307 0.4202 0.5484
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0023 0.0246 0.048
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0781 0.0782
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2325 0.4852
Mycobacterium ulcerans DNA polymerase IV 0.0011 0.0076 0.0056
Trypanosoma cruzi peter pan protein, putative 0.0025 0.0272 0.1659
Schistosoma mansoni hypothetical protein 0.001 0.0067 0.0067
Brugia malayi nuclear receptor RXR 0.0016 0.0145 0.0189
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0029 0.0325 0.0326
Trichomonas vaginalis maltase-glucoamylase, putative 0.0028 0.0316 0.0659
Onchocerca volvulus 0.0047 0.0585 0.122
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0028 0.0315 0.2356
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Loa Loa (eye worm) doublecortin family protein 0.001 0.0067 0.0142
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0343 0.0344
Echinococcus granulosus cpg binding protein 0.0013 0.0105 0.0106
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0325 0.0326
Schistosoma mansoni biogenic amine receptor 0.0029 0.0325 0.0326
Loa Loa (eye worm) hypothetical protein 0.003 0.0343 0.0733
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0186 0.0402
Schistosoma mansoni ap endonuclease 0.0019 0.0186 0.0187
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.0067 0.0067
Brugia malayi G protein-coupled receptor 0.0029 0.0325 0.0424
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0044 0.0539 0.081
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0325 0.0326
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0006 0.0004 0.0004
Onchocerca volvulus 0.001 0.0067 0.0139
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.009 0.1173 0.1175
Entamoeba histolytica recQ family DNA helicase 0.001 0.0062 0.0107
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0086 0.1124 0.2411
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0054 0.0112
Schistosoma mansoni bromodomain containing protein 0.0065 0.0828 0.083
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.01 0.01
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0325 0.0326
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.3585 0.7479
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0325 0.0326
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0191
Schistosoma mansoni DNA helicase recq5 0.002 0.0197 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.0008 0.0029 0.0001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0227 0.0199
Mycobacterium tuberculosis Conserved hypothetical protein 0.0045 0.0556 0.0529
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0012 0.009 0.0047
Mycobacterium ulcerans endonuclease IV 0.0083 0.108 0.1754
Echinococcus granulosus tumor protein p63 0.0333 0.4564 0.4571
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0343 0.0344
Echinococcus multilocularis dna polymerase kappa 0.0011 0.0076 0.0076
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0008 0.0028 0.0028
Echinococcus granulosus lamin dm0 0.0025 0.0268 0.0268
Echinococcus granulosus g protein coupled receptor 0.0029 0.0325 0.0326
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2325 0.4852
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0548 0.1143
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.15 0.313
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0432 0.0433
Schistosoma mansoni neuropeptide receptor 0.0029 0.0325 0.0326
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.009 0.1173 0.1531
Onchocerca volvulus 0.0029 0.0325 0.0678
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Schistosoma mansoni phosphoglucomutase 0.0016 0.0141 0.0141
Mycobacterium leprae Probable lipase LipE 0.0113 0.15 0.2465
Brugia malayi glutathione reductase 0.0011 0.0079 0.0104
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0548 0.1143
Echinococcus multilocularis G protein coupled receptor 139 0.0029 0.0325 0.0326
Schistosoma mansoni inositol monophosphatase 0.0038 0.0454 0.0455
Entamoeba histolytica acyl-coA synthetase, putative 0.0017 0.0166 0.1034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0343 0.0448
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.1305 0.1307
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0065 0.0836 0.7591
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0159 0.0892
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.2325 0.4852
Brugia malayi ImpB/MucB/SamB family protein 0.0018 0.0178 0.0232
Loa Loa (eye worm) hypothetical protein 0.0016 0.0145 0.0309
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0086 0.1124 0.7448
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0197 0.0228
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0343 0.0716
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0325 0.0326
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.15 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.0003
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0447 0.0448
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0491 0.3148
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Schistosoma mansoni single-minded 0.0036 0.0426 0.0427
Onchocerca volvulus 0.0113 0.15 0.313
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0008 0.0028 0.0028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0343 0.0344
Echinococcus granulosus neuropeptide receptor A26 0.0503 0.6944 0.6955
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0017 0.0159 0.0916
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0409 0.0853
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0009 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0326 0.0696
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0121 0.0158
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0009 0.005 0.0105
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0447 0.0448
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0065 0.0836 0.109
Brugia malayi neuropeptide F receptor 0.0029 0.0325 0.0424
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0978 0.6456
Echinococcus granulosus microtubule associated protein 2 0.0721 0.9984 1
Trichomonas vaginalis NeSL-1_NeSL reverse transcriptases, putative 0.0008 0.0028 0.0059
Loa Loa (eye worm) hypothetical protein 0.0043 0.0517 0.1105
Entamoeba histolytica hypothetical protein 0.0037 0.0433 0.3408
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0011 0.0076 0.0048
Trichomonas vaginalis guanylate cyclase, putative 0.0009 0.0054 0.0112
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0017 0.0166 0.0167
Schistosoma mansoni DNA polymerase eta 0.0018 0.0178 0.0178
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0016 0.0141 0.0275
Treponema pallidum ribonuclease H (rnhA) 0.0016 0.0141 0.0275
Plasmodium vivax metacaspase 1, putative 0.0045 0.0548 0.3401
Brugia malayi Cell death protein 3 precursor 0.0086 0.113 0.1475
Brugia malayi RE15519p 0.0029 0.0325 0.0424
Schistosoma mansoni DNA helicase recq1 0.002 0.0197 0.0197
Toxoplasma gondii brix domain-containing protein 0.0025 0.0272 0.0356
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0197 0.0256
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0017 0.0159 0.0892
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0015 0.0125 0.0497
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0113 0.15 0.1958
Echinococcus multilocularis lamin 0.0025 0.0268 0.0268
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0197 0.0197
Onchocerca volvulus 0.0049 0.0602 0.1256
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0343 0.0344
Echinococcus granulosus dna polymerase kappa 0.0011 0.0076 0.0076
Onchocerca volvulus 0.0009 0.0054 0.0112
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0029 0.0325 0.0326
Schistosoma mansoni ap endonuclease 0.0019 0.0186 0.0187
Loa Loa (eye worm) CXXC zinc finger family protein 0.0011 0.007 0.0149
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0316 0.0659
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0008 0.0028 0.0028
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0028 0.0315 0.1947
Onchocerca volvulus 0.0014 0.0115 0.0239
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0076 0.0106
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0029 0.0325 0.0326
Trypanosoma cruzi DNA polymerase kappa, putative 0.0011 0.0076 0.0327
Brugia malayi RNase H family protein 0.0016 0.0141 0.0184
Brugia malayi Tachykinin-like peptides receptor 99D 0.0029 0.0325 0.0424
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Echinococcus multilocularis lysosomal alpha glucosidase 0.0341 0.468 0.4688
Trichomonas vaginalis set domain proteins, putative 0.0349 0.4793 1
Toxoplasma gondii ABC1 family protein 0.0113 0.15 0.244
Schistosoma mansoni scy1(yeast) protein kinase-like 0.0008 0.0028 0.0028
Echinococcus multilocularis g-protein coupled receptor 0.0029 0.0325 0.0326
Echinococcus granulosus orexin receptor type 2 0.0029 0.0325 0.0326
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0454 0.1154
Schistosoma mansoni apoferritin-2 0.0009 0.0043 0.0043
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0227 0.0311
Echinococcus multilocularis p2X purinoceptor 4 0.0039 0.0463 0.0463
Schistosoma mansoni alpha-1 adrenergic receptor 0.0029 0.0325 0.0326
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0432 0.0433
Onchocerca volvulus 0.0113 0.15 0.313
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0006 0.001 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.1305 0.1307
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0027 0.0298 0.1831
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0379 0.2928
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0379 0.0537
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0009 0.005 0.0066
Schistosoma mansoni peter pan-related 0.0025 0.0272 0.0273
Echinococcus multilocularis raf serine:threonine protein kinase 0.0019 0.0181 0.0181
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0978 0.6456
Trypanosoma cruzi ribonuclease H1, putative 0.0016 0.0141 0.0767
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0343 0.0344
Toxoplasma gondii histone lysine methyltransferase SET1 0.0024 0.0258 0.0332
Trypanosoma brucei DNA polymerase kappa, putative 0.0008 0.0029 0.0001
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0227 0.0296
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0978 0.2041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Brugia malayi hypothetical protein 0.0028 0.0318 0.0415
Schistosoma mansoni apoferritin-2 0.0009 0.0043 0.0043
Brugia malayi hypothetical protein 0.0008 0.0028 0.0037
Leishmania major pyruvate kinase 0.0035 0.0409 0.2458
Schistosoma mansoni ferritin 0.0009 0.0043 0.0043
Loa Loa (eye worm) translation initiation factor 4E 0.0028 0.0315 0.0672
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0029 0.0325 0.0424
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0009 0.0054 0.0173
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Loa Loa (eye worm) hypothetical protein 0.0024 0.0262 0.056
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2325 0.4852
Leishmania major hypothetical protein, conserved 0.0028 0.0318 0.1829
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0047 0.0575 0.0576
Loa Loa (eye worm) raf kinase 0.0019 0.0181 0.0387
Toxoplasma gondii hypothetical protein 0.0014 0.0117 0.0092
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Loa Loa (eye worm) hypothetical protein 0.0013 0.0105 0.0224
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.009 0.1173 0.7778
Echinococcus multilocularis orexin receptor type 2 0.0029 0.0325 0.0326
Loa Loa (eye worm) hypothetical protein 0.002 0.0197 0.042
Schistosoma mansoni ferritin light chain 0.0009 0.0043 0.0043
Brugia malayi Pre-SET motif family protein 0.0044 0.0539 0.0704
Plasmodium falciparum metacaspase 1 0.0045 0.0548 0.475
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0454 0.0665
Schistosoma mansoni ATP-diphosphohydrolase 1 0.0012 0.009 0.009
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0343 0.0448
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0343 0.0733
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0454 0.2769
Loa Loa (eye worm) hypothetical protein 0.003 0.0343 0.0733
Entamoeba histolytica recQ family helicase, putative 0.001 0.0057 0.006
Brugia malayi hypothetical protein 0.0029 0.0325 0.0424
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0009 0.005 0.0066
Echinococcus multilocularis p2X purinoceptor 4 0.0039 0.0463 0.0463
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0121 0.0158
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0343 0.0733
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0454 0.0947
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0026 0.028 0.0281
Trichomonas vaginalis ribonuclease H1, putative 0.0016 0.0141 0.0294
Onchocerca volvulus 0.0113 0.15 0.313
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0409 0.0619
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0165 0.0165
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0017 0.0166 0.0167
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0017 0.0159 0.071
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0264 0.3606 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0602 0.1286
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.1305 0.1307
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Onchocerca volvulus 0.0025 0.0268 0.0559
Giardia lamblia Rab geranylgeranyltransferase 0.0017 0.0159 0.1626
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0028 0.032 0.0469
Brugia malayi beta-lactamase 0.0113 0.15 0.1958
Schistosoma mansoni phosphoglucomutase 0.0016 0.0141 0.0141
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0409 0.0534
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0343 0.0448
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0186 0.0187
Schistosoma mansoni hypothetical protein 0.0021 0.0215 0.0216
Echinococcus multilocularis lamin dm0 0.0025 0.0268 0.0268
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2325 0.4852
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.15 0.1502
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0014 0.0115 0.015
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0325 0.0326
Brugia malayi AKH receptor 0.0029 0.0325 0.0424
Trypanosoma brucei cytochrome P450, putative 0.0012 0.0087 0.013
Trichomonas vaginalis sucrase-isomaltase, putative 0.0076 0.0978 0.2041
Echinococcus multilocularis Polycystic kidney disease protein 0.001 0.0067 0.0067
Schistosoma mansoni guanosine-diphosphatase 0.0012 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Brugia malayi follicle stimulating hormone receptor 0.0231 0.3151 0.4113
Schistosoma mansoni amine GPCR 0.0029 0.0325 0.0326
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0343 0.0344
Plasmodium vivax acyl-CoA synthetase, putative 0.0013 0.0105 0.0331
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0254 0.0496
Brugia malayi nuclear receptor RXR 0.0014 0.0121 0.0158
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0978 0.2041
Loa Loa (eye worm) hypoxia-induced factor 1 0.0112 0.1481 0.3165
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0251 0.0251
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0197 0.0197
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0011 0.007 0.0091
Toxoplasma gondii ribonuclease HI protein 0.0016 0.0141 0.0134
Loa Loa (eye worm) hypothetical protein 0.0009 0.005 0.0107
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.0003
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0343 0.0344
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0125 0.0126
Onchocerca volvulus 0.0029 0.0325 0.0678
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0054 0.0112
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0409 0.0853
Trypanosoma cruzi DNA polymerase kappa, putative 0.0011 0.0076 0.0327
Onchocerca volvulus 0.001 0.0067 0.0139
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0409 0.0534
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.0268 0.0572
Schistosoma mansoni hypothetical protein 0.0008 0.0028 0.0028
Entamoeba histolytica deoxycytidyl transferase, putative 0.0011 0.0076 0.0232
Schistosoma mansoni ferritin light chain 0.0009 0.0043 0.0043
Brugia malayi G-protein coupled receptor 0.0029 0.0325 0.0424
Echinococcus multilocularis ribonuclease H1 0.0016 0.0141 0.0141
Leishmania major DNA polymerase kappa, putative 0.0011 0.0076 0.0157
Echinococcus multilocularis caspase 2 0.0086 0.113 0.1132
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0447 0.0583
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0029 0.0325 0.0695
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0264 0.3606 0.6021
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0447 0.5189
Echinococcus multilocularis G-protein coupled receptor, putative 0.0029 0.0325 0.0326
Brugia malayi larval opioid receptor 0.0029 0.0325 0.0424
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0316 0.0659
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0017 0.0159 0.016
Giardia lamblia Kinase, CMGC MAPK 0.0015 0.0125 0.1206
Loa Loa (eye worm) hypothetical protein 0.0041 0.05 0.1069
Brugia malayi hypothetical protein 0.0008 0.0028 0.0037
Schistosoma mansoni rotamase 0.0033 0.039 0.0391
Trypanosoma cruzi nucleoside phosphatase, putative 0.0012 0.009 0.0422
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0409 0.0874
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0009 0.0054 0.0112
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0325 0.0326
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0325 0.0326
Trypanosoma brucei brix domain containing protein, putative 0.0025 0.0272 0.0537
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0029 0.0325 0.0326
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0325 0.0326
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0028 0.032 0.0293
Schistosoma mansoni neuropeptide f receptor 76f 0.0029 0.0325 0.0326
Loa Loa (eye worm) hypothetical protein 0.003 0.0343 0.0733
Loa Loa (eye worm) hypothetical protein 0.0038 0.0447 0.0955
Leishmania major trypanothione reductase 0.0011 0.0079 0.0179
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0447 0.0448
Echinococcus multilocularis zinc finger protein 598 0.0025 0.027 0.0271
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Brugia malayi CXXC zinc finger family protein 0.0011 0.007 0.0091
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0454 0.2894
Echinococcus multilocularis ryanodine receptor 44f 0.0018 0.0169 0.017
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0121 0.0158
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.009 0.1173 0.1175
Onchocerca volvulus 0.0029 0.0325 0.0678
Loa Loa (eye worm) hypothetical protein 0.0012 0.009 0.0193
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0318 0.181
Schistosoma mansoni opsin-like receptor 0.0029 0.0325 0.0326
Trypanosoma brucei unspecified product 0.0023 0.0246 0.048
Leishmania major eukaryotic translation initiation factor-like 0.0028 0.0315 0.1805
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Loa Loa (eye worm) hypothetical protein 0.0013 0.0105 0.0224
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0186 0.0398
Schistosoma mansoni nuclear receptor 0.0014 0.0121 0.0121
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0011 0.0076 0.0159
Schistosoma mansoni hypothetical protein 0.0016 0.0148 0.0149
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0145 0.0189
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0028 0.0315 0.0315
Echinococcus multilocularis neutral alpha glucosidase AB 0.0076 0.0978 0.098
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0012 0.009 0.0188
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Brugia malayi hypoxia-induced factor 1 0.0112 0.1481 0.1933
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0343 0.0448
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0044 0.0539 0.054
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0009 0.005 0.005
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0029 0.0325 0.0326
Schistosoma mansoni hypothetical protein 0.0333 0.4576 0.4583
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0017 0.0166 0.0139
Loa Loa (eye worm) thioredoxin reductase 0.0011 0.0079 0.017
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0121 0.0121
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0009 0.0054 0.0115
Onchocerca volvulus 0.0008 0.0028 0.0059
Brugia malayi tailless protein 0.0014 0.0121 0.0158
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0409 0.244
Schistosoma mansoni survival motor neuron protein 0.0014 0.0115 0.0115
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.1305 0.1307
Treponema pallidum ATP-dependent DNA helicase 0.001 0.0062 0.0054
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0009 0.005 0.005
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0409 0.2588
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0017 0.0166 0.0209
Echinococcus granulosus expressed protein 0.0033 0.039 0.0391
Schistosoma mansoni caspase-7 (C14 family) 0.0118 0.1575 0.1578
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0343 0.0344
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0343 0.0344
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0433 0.0434
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.2455 0.5121
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0343 0.0448
Brugia malayi GnHR receptor homolog 0.0555 0.7662 1
Plasmodium falciparum metacaspase-like protein 0.0045 0.0548 0.475
Brugia malayi Pao retrotransposon peptidase family protein 0.0008 0.0028 0.0037
Trypanosoma brucei unspecified product 0.0008 0.0029 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0517 0.1105
Trypanosoma brucei glucosidase, putative 0.0076 0.0978 0.209
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0011 0.0079 0.0052
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0343 0.0448
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0145 0.0145
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0015 0.0125 0.0497
Echinococcus multilocularis pyruvate kinase 0.0018 0.0172 0.0173
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0009 0.005 0.0066
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0028 0.0315 0.2356
Loa Loa (eye worm) hypothetical protein 0.0067 0.0864 0.1845
Onchocerca volvulus 0.0027 0.0295 0.0616
Brugia malayi Protein kinase domain containing protein 0.0009 0.0047 0.0062
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0121 0.0121
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0121 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.15 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0491 0.3027
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0017 0.0159 0.0892
Echinococcus granulosus transcription factor Dp 1 0.0052 0.0646 0.0647
Loa Loa (eye worm) hypothetical protein 0.0113 0.15 0.3205
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0343 0.0733
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0017 0.0166 0.0167
Echinococcus granulosus pyruvate kinase 0.0035 0.0409 0.041
Onchocerca volvulus 0.0029 0.0325 0.0678
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0121 0.0121
Schistosoma mansoni amine GPCR 0.0029 0.0325 0.0326
Brugia malayi pyruvate kinase, muscle isozyme 0.0007 0.0025 0.0033
Trypanosoma brucei unspecified product 0.0008 0.0029 0.0001
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0006 0.0004 0.0004
Echinococcus granulosus pyruvate kinase 0.0035 0.0409 0.041
Onchocerca volvulus 0.0029 0.0326 0.068
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0432 0.5954 1
Echinococcus granulosus sex peptide receptor 0.0029 0.0325 0.0326
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0121 0.0121
Giardia lamblia Rab geranylgeranyltransferase 0.0065 0.0836 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0325 0.0326
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0978 0.2041
Loa Loa (eye worm) CYP4Cod1 0.0012 0.0087 0.0186
Echinococcus granulosus RNA directed DNA polymerase 0.0008 0.0028 0.0028
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0548 0.0824
Onchocerca volvulus 0.0042 0.0505 0.1053
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0113 0.15 0.1476
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0026 0.028 0.0281
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0447 0.2846
Brugia malayi Dopamine receptor protein 1 0.0029 0.0325 0.0424
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0086 0.1124 0.7448
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0454 0.2894
Schistosoma mansoni hypothetical protein 0.0008 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0113 0.15 0.3205
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0325 0.0326
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0012 0.0089 0.0089
Schistosoma mansoni cpg binding protein 0.0011 0.007 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.003 0.003
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0065 0.0836 0.1743
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0398 0.0371
Echinococcus granulosus peter pan 0.0025 0.0272 0.0273
Echinococcus multilocularis sex peptide receptor 0.0029 0.0325 0.0326
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0165 0.0165
Schistosoma mansoni inositol 145-trisphosphate receptor 0.004 0.0476 0.0476
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0065 0.0836 0.1743
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0447 0.0448
Plasmodium vivax thioredoxin reductase, putative 0.0011 0.0079 0.0156
Mycobacterium tuberculosis Conserved protein 0.0113 0.15 0.1476
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0454 0.0947
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Echinococcus granulosus neutral alpha glucosidase AB 0.0076 0.0978 0.098
Onchocerca volvulus 0.0029 0.0325 0.0678
Brugia malayi hypothetical protein 0.0029 0.0325 0.0424
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0076 0.0106
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0343 0.0448
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0343 0.0733
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0012 0.009 0.009
Brugia malayi hypothetical protein 0.0037 0.0433 0.0565
Leishmania major cytochrome p450-like protein 0.0012 0.0087 0.0231
Trypanosoma brucei protein kinase, putative 0.0015 0.0125 0.0214
Brugia malayi F/Y-rich N-terminus family protein 0.0007 0.0017 0.0023
Mycobacterium tuberculosis Conserved protein 0.0113 0.15 0.1476
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0062 0.0232
Loa Loa (eye worm) hypothetical protein 0.001 0.0067 0.0142
Brugia malayi bHLH-PAS transcription factor 0.0027 0.0295 0.0386
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0316 0.1955
Brugia malayi hypothetical protein 0.0029 0.0325 0.0424
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0121 0.0158
Loa Loa (eye worm) hypothetical protein 0.0017 0.0166 0.0355
Giardia lamblia Pyruvate kinase 0.0018 0.0172 0.1786
Echinococcus granulosus lysosomal alpha glucosidase 0.0341 0.468 0.4688
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0978 0.2041
Trypanosoma cruzi ISWI complex protein 0.0016 0.014 0.0758
Schistosoma mansoni lipoxygenase 0.0028 0.0316 0.0317
Brugia malayi Brix domain containing protein 0.0025 0.0272 0.0355
Trypanosoma brucei trypanothione reductase 0.0011 0.0079 0.0113
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0166 0.0139
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0215 0.046
Brugia malayi beta-lactamase family protein 0.0113 0.15 0.1958
Loa Loa (eye worm) hypothetical protein 0.0113 0.15 0.3205
Brugia malayi intermediate filament protein 0.0025 0.0268 0.035
Echinococcus multilocularis geminin 0.0359 0.4938 0.4946
Loa Loa (eye worm) hypothetical protein 0.0016 0.0145 0.0309
Brugia malayi Bromodomain containing protein 0.0077 0.0995 0.1298
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0548 0.1143
Chlamydia trachomatis dehyroquinate synthase 0.0168 0.227 0.3757
Schistosoma mansoni phosphoglucomutase 0.0016 0.0141 0.0141
Brugia malayi AMP-binding enzyme family protein 0.0017 0.0166 0.0217
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0076 0.0106
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0343 0.0448
Trypanosoma brucei metacaspase MCA3 0.0045 0.0548 0.1143
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0548 0.1143
Trypanosoma cruzi peter pan protein, putative 0.0025 0.0272 0.1659
Loa Loa (eye worm) hypothetical protein 0.0014 0.0121 0.0259
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0012 0.0095 0.0067
Brugia malayi Melatonin receptor type 1A 0.0029 0.0325 0.0424
Brugia malayi hypothetical protein 0.0014 0.0121 0.0158
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0186 0.0159
Echinococcus granulosus ryanodine receptor 44f 0.0023 0.0241 0.0241
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0045 0.0548 0.0715
Loa Loa (eye worm) hypothetical protein 0.0028 0.0316 0.0675
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0343 0.0344
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0065 0.0836 0.1785
Onchocerca volvulus 0.0029 0.0325 0.0678
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0186 0.0348
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0026 0.028 0.0253
Echinococcus granulosus zinc finger protein 598 0.0025 0.027 0.0271
Brugia malayi hypothetical protein 0.0029 0.0325 0.0424
Trypanosoma brucei DNA polymerase eta, putative 0.0018 0.0178 0.0329
Schistosoma mansoni amine GPCR 0.0029 0.0325 0.0326
Giardia lamblia Pyruvate kinase 0.0035 0.0409 0.4718
Schistosoma mansoni pyruvate kinase 0.0035 0.0409 0.041
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0015 0.0125 0.0214
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0224 0.048
Echinococcus multilocularis lysosomal alpha glucosidase 0.0341 0.468 0.4688
Echinococcus granulosus neuropeptide FF receptor 2 0.0029 0.0325 0.0326
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0409 0.0853
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0695
Brugia malayi Dopamine receptor 0.0029 0.0325 0.0424
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0432 0.5954 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0047 0.0585 0.0586
Mycobacterium ulcerans esterase/lipase LipP 0.0113 0.15 0.2465
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0325 0.0326
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.1305 0.2789
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0029 0.0325 0.0326
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.0003
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0062 0.0232
Brugia malayi hypothetical protein 0.0008 0.0028 0.0037
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.1305 0.1704
Echinococcus granulosus ferritin 0.0009 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0178 0.038
Schistosoma mansoni thyroid hormone receptor 0.003 0.0343 0.0344
Loa Loa (eye worm) hypothetical protein 0.003 0.0343 0.0733
Loa Loa (eye worm) hypothetical protein 0.0028 0.0318 0.068
Loa Loa (eye worm) hypothetical protein 0.003 0.0343 0.0733
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0264 0.3606 1
Echinococcus granulosus allatostatin A receptor 0.0029 0.0325 0.0326
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0121 0.0121
Echinococcus granulosus pyruvate kinase 0.0018 0.0172 0.0173
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0325 0.0326

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 160 nM Cytotoxicity of the compound was evaluated at 1 microM concentration in MCF7-R cell line when co-administered with Paclitaxel ChEMBL. 9871652
IC50 (functional) = 160 nM Cytotoxicity of the compound was evaluated at 1 microM concentration in MCF7-R cell line when co-administered with Paclitaxel ChEMBL. 9871652
Reduction (functional) = 81 % Compound was evaluated for multi-drug resistance (MDR) reversal at 1 microM concentration in MCF7-R cell line when co-administered with Paclitaxel ChEMBL. 9871652
Reduction (functional) = 81 % Compound was evaluated for multi-drug resistance (MDR) reversal at 1 microM concentration in MCF7-R cell line when co-administered with Paclitaxel ChEMBL. 9871652

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 9871652

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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