TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 325.752 | Formula: C16H12ClN5O
H donors: 2 H acceptors: 4 LogP: 3.41 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: Clc1ccc(cc1)C=NNc1nnc(c(n1)O)c1ccccc1
InChi: 1S/C16H12ClN5O/c17-13-8-6-11(7-9-13)10-18-21-16-19-15(23)14(20-22-16)12-4-2-1-3-5-12/h1-10H,(H2,19,21,22,23)/b18-10+
InChiKey: GAKYGOHAGOJQHF-VCHYOVAHSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0054	0.0619	1
Leishmania major	short chain dehydrogenase-like protein	0.0008	0.0053	0.5
Schistosoma mansoni	3-hydroxyacyl-CoA dehydrogenase	0.0008	0.0053	0.0301
Schistosoma mansoni	adenoreceptor	0.0054	0.0619	0.3514
Leishmania major	short chain dehydrogenase, putative	0.0008	0.0053	0.5
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0054	0.0619	0.3514
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0054	0.0619	1
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0054	0.0619	0.3514
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0054	0.0619	0.3514
Trichomonas vaginalis	conserved hypothetical protein	0.0207	0.2469	0.2429
Schistosoma mansoni	hypothetical protein	0.0054	0.0619	0.3514
Echinococcus granulosus	retinol dehydrogenase 11	0.0008	0.0053	0.0301
Echinococcus granulosus	rhodopsin orphan GPCR	0.0054	0.0619	0.3514
Onchocerca volvulus		0.0054	0.0619	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0054	0.0619	0.3514
Brugia malayi	putative neuropeptide receptor NPR1	0.0054	0.0619	1
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Trypanosoma cruzi	hypothetical protein, conserved	0.0008	0.0053	0.5
Brugia malayi	hypothetical protein	0.0008	0.0053	0.0813
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Brugia malayi	GnHR receptor homolog	0.0054	0.0619	1
Onchocerca volvulus		0.0054	0.0619	1
Echinococcus multilocularis	neuropeptide s receptor	0.0054	0.0619	1
Onchocerca volvulus		0.0054	0.0619	1
Echinococcus multilocularis	g protein coupled receptor	0.0054	0.0619	1
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0054	0.0619	0.3514
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0054	0.0619	1
Echinococcus multilocularis	neuropeptide receptor	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0053	0.0856
Echinococcus multilocularis	neuropeptide Y receptor	0.0054	0.0619	1
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Trichomonas vaginalis	conserved hypothetical protein	0.0207	0.2469	0.2429
Brugia malayi	AKH receptor	0.0054	0.0619	1
Echinococcus granulosus	G protein coupled receptor 139	0.0054	0.0619	0.3514
Brugia malayi	sulfakinin receptor protein	0.0054	0.0619	1
Schistosoma mansoni	oxidoreductase short chain dehydrogenase/reductase family	0.0008	0.0053	0.0301
Brugia malayi	G protein-coupled receptor	0.0054	0.0619	1
Echinococcus multilocularis	sex peptide receptor	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Echinococcus multilocularis	carbonyl reductase 1	0.0008	0.0053	0.0856
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0054	0.0619	1
Entamoeba histolytica	modulator of drug activity B homolog, putative	0.0207	0.2469	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0054	0.0619	0.3514
Leishmania major	quinonoid dihydropteridine reductase	0.0008	0.0053	0.5
Echinococcus granulosus	fmrfamide receptor	0.0054	0.0619	0.3514
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0054	0.0619	1
Loa Loa (eye worm)	oxidoreductase	0.0008	0.0053	0.0856
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0054	0.0619	1
Leishmania major	quinonoid dihydropteridine reductase	0.0008	0.0053	0.5
Leishmania major	quinonoid dihydropteridine reductase	0.0008	0.0053	0.5
Trypanosoma brucei	short-chain dehydrogenase, putative	0.0008	0.0053	0.5
Echinococcus granulosus	g-protein coupled receptor	0.0054	0.0619	0.3514
Onchocerca volvulus		0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Echinococcus granulosus	neuropeptide Y receptor	0.0054	0.0619	0.3514
Echinococcus granulosus	neuropeptide receptor	0.0054	0.0619	0.3514
Leishmania major	hypothetical protein, conserved	0.0008	0.0053	0.5
Echinococcus multilocularis	serotonin receptor	0.0054	0.0619	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0054	0.0619	0.3514
Brugia malayi	hypothetical protein	0.0054	0.0619	1
Brugia malayi	dehydrogenases, short chain protein 2	0.0008	0.0053	0.0813
Brugia malayi	Dehydrogenases, short chain protein 2	0.0008	0.0053	0.0813
Mycobacterium tuberculosis	Possible formate hydrogenlyase HycD (FHL)	0.004	0.0446	0.06
Loa Loa (eye worm)	oxidoreductase	0.0008	0.0053	0.0856
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Trypanosoma cruzi	quinonoid dihydropteridine reductase, putative	0.0008	0.0053	0.5
Brugia malayi	G protein-coupled receptor F59B2.13	0.0054	0.0619	1
Echinococcus multilocularis	neuropeptide receptor	0.0054	0.0619	1
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0054	0.0619	1
Echinococcus multilocularis	3 ketodihydrosphingosine reductase	0.0008	0.0053	0.0856
Trypanosoma brucei	3-keto-dihydrosphingosine reductase	0.0008	0.0053	0.5
Schistosoma mansoni	neuropeptide receptor	0.0054	0.0619	0.3514
Schistosoma mansoni	opsin-like receptor	0.0054	0.0619	0.3514
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0054	0.0619	0.3514
Brugia malayi	Melatonin receptor type 1A	0.0054	0.0619	1
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0054	0.0619	0.3514
Echinococcus multilocularis	steroid dehydrogenase	0.0008	0.0053	0.0856
Echinococcus multilocularis	neuropeptide Y receptor	0.0054	0.0619	1
Echinococcus multilocularis	g protein coupled receptor	0.0054	0.0619	1
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Toxoplasma gondii	3-ketoacyl-CoA reductase, putative	0.0008	0.0053	0.5
Brugia malayi	hypothetical protein	0.0054	0.0619	1
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0054	0.0619	0.3514
Brugia malayi	ORL1-like opioid receptor	0.0054	0.0619	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0054	0.0619	0.3514
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0054	0.0619	1
Schistosoma mansoni	steroid dehydrogenase	0.0008	0.0053	0.0301
Echinococcus granulosus	rhodopsin orphan GPCR	0.0054	0.0619	0.3514
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Brugia malayi	hypothetical protein	0.0054	0.0619	1
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Onchocerca volvulus		0.0054	0.0619	1
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0054	0.0619	1
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Trypanosoma cruzi	short-chain dehydrogenase, putative	0.0008	0.0053	0.5
Schistosoma mansoni	opsin-like receptor	0.0054	0.0619	0.3514
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0054	0.0619	1
Leishmania major	quinonoid dihydropteridine reductase	0.0008	0.0053	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0008	0.0053	0.5
Toxoplasma gondii	carbonyl reductase 1, putative	0.0008	0.0053	0.5
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0003	0.0047
Toxoplasma gondii	sterol carrier protein-2 HAD-2SCP-2	0.0008	0.0053	0.5
Mycobacterium leprae	Probable short-chain type dehydrogenase/reductase	0.0008	0.0053	0.5
Trypanosoma cruzi	short-chain dehydrogenase, putative	0.0008	0.0053	0.5
Wolbachia endosymbiont of Brugia malayi	NADH dehydrogenase subunit H	0.0148	0.1761	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Trypanosoma cruzi	oxidoreductase-like protein, putative	0.0008	0.0053	0.5
Giardia lamblia	NADPH oxidoreductase, putative	0.0828	1	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0054	0.0619	0.3514
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	short chain dehydrogenase/reductase family oxidoreductase	0.0008	0.0053	0.0856
Schistosoma mansoni	neuropeptide receptor	0.0054	0.0619	0.3514
Brugia malayi	hypothetical protein	0.0008	0.0053	0.0813
Trypanosoma cruzi	3-keto-dihydrosphingosine reductase	0.0008	0.0053	0.5
Brugia malayi	putative neuropeptide receptor	0.0054	0.0619	1
Schistosoma mansoni	neuropeptide receptor	0.0054	0.0619	0.3514
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Echinococcus granulosus	hypothetical protein	0.0054	0.0619	0.3514
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Loa Loa (eye worm)	dehydrogenase	0.0008	0.0053	0.0856
Echinococcus granulosus	neuropeptide s receptor	0.0054	0.0619	0.3514
Echinococcus granulosus	neuropeptide receptor	0.0054	0.0619	0.3514
Echinococcus multilocularis	retinol dehydrogenase 11	0.0008	0.0053	0.0856
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Brugia malayi	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	oxidoreductase	0.0008	0.0053	0.0856
Echinococcus multilocularis	somatostatin receptor	0.0054	0.0619	1
Schistosoma mansoni	opsin-like receptor	0.0054	0.0619	0.3514
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0054	0.0619	0.3514
Echinococcus granulosus	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0008	0.0053	0.0301
Trichomonas vaginalis	conserved hypothetical protein	0.0207	0.2469	0.2429
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Schistosoma mansoni	carbonyl reductase	0.0008	0.0053	0.0301
Toxoplasma gondii	oxidoreductase, putative	0.0008	0.0053	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0008	0.0053	0.5
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Brugia malayi	hypothetical protein	0.0054	0.0619	1
Echinococcus granulosus	neuropeptide receptor A26	0.0054	0.0619	0.3514
Schistosoma mansoni	transient receptor potential channel	0.0003	0.0003	0.0017
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0054	0.0619	1
Schistosoma mansoni	amine GPCR	0.0054	0.0619	0.3514
Leishmania major	short chain dehydrogenase, putative	0.0008	0.0053	0.5
Echinococcus multilocularis	short transient receptor potential channel 6	0.0003	0.0003	0.0047
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0054	0.0619	1
Echinococcus granulosus	carbonyl reductase 1	0.0008	0.0053	0.0301
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0054	0.0619	1
Entamoeba histolytica	iron-sulfur flavoprotein, putative	0.0207	0.2469	1
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Schistosoma mansoni	neuropeptide F-like receptor	0.0054	0.0619	0.3514
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0054	0.0619	0.3514
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Schistosoma mansoni	amine GPCR	0.0054	0.0619	0.3514
Echinococcus multilocularis	retinol dehydrogenase 11	0.0008	0.0053	0.0856
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Echinococcus granulosus	short transient receptor potential channel 6	0.0003	0.0003	0.0017
Loa Loa (eye worm)	oxidoreductase	0.0008	0.0053	0.0856
Brugia malayi	hypothetical protein	0.0054	0.0619	1
Trypanosoma cruzi	hypothetical protein, conserved	0.0008	0.0053	0.5
Plasmodium vivax	hypothetical protein, conserved	0.0008	0.0053	0.5
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0054	0.0619	0.3514
Echinococcus granulosus	neuropeptide FF receptor 2	0.0054	0.0619	0.3514
Echinococcus granulosus	dro:myosuppressin receptor	0.0054	0.0619	0.3514
Onchocerca volvulus		0.004	0.0446	0.6943
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0054	0.0619	0.3514
Echinococcus granulosus	rhodopsin orphan GPCR	0.0054	0.0619	0.3514
Trypanosoma cruzi	NAD(P)-dependent oxidoreductase, putative	0.0008	0.0053	0.5
Echinococcus granulosus	retinol dehydrogenase 11	0.0008	0.0053	0.0301
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0054	0.0619	0.3514
Echinococcus granulosus	neuropeptides capa receptor	0.0054	0.0619	0.3514
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0054	0.0619	1
Trypanosoma brucei	beta-ketoacyl-ACP reductase 3, putative	0.0008	0.0053	0.5
Brugia malayi	G-protein coupled receptor	0.0054	0.0619	1
Echinococcus granulosus	orexin receptor type 2	0.0054	0.0619	0.3514
Onchocerca volvulus		0.0054	0.0619	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0054	0.0619	0.3514
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0054	0.0619	0.3514
Schistosoma mansoni	neuropeptide receptor	0.0054	0.0619	0.3514
Trypanosoma cruzi	3-ketoacyl-CoA reductase, putative	0.0008	0.0053	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0054	0.0619	0.3514
Trypanosoma brucei	short-chain dehydrogenase, putative	0.0008	0.0053	0.5
Echinococcus granulosus	transient receptor potential cation channel	0.0003	0.0003	0.0017
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0054	0.0619	1
Schistosoma mansoni	histamine h1 receptor	0.0054	0.0619	0.3514
Trichomonas vaginalis	conserved hypothetical protein	0.0621	0.7492	0.7478
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0054	0.0619	1
Leishmania major	quinonoid dihydropteridine reductase	0.0008	0.0053	0.5
Echinococcus multilocularis	Dehydrogenase:reductase SDR family	0.0008	0.0053	0.0856
Leishmania major	hypothetical protein, conserved	0.0008	0.0053	0.5
Schistosoma mansoni	steroid dehydrogenase	0.0008	0.0053	0.0301
Schistosoma mansoni	steroid dehydrogenase	0.0008	0.0053	0.0301
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0054	0.0619	1
Echinococcus multilocularis	transient receptor potential cation channel	0.0008	0.0053	0.0856
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Schistosoma mansoni	biogenic amine receptor	0.0054	0.0619	0.3514
Mycobacterium leprae	Probable short-chain type dehydrogenase/reductase	0.0008	0.0053	0.5
Echinococcus granulosus	biogenic amine 5HT receptor	0.0054	0.0619	0.3514
Leishmania major	pteridine reductase 1	0.0008	0.0053	0.5
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Onchocerca volvulus		0.0054	0.0619	1
Schistosoma mansoni	hypothetical protein	0.0054	0.0619	0.3514
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0054	0.0619	1
Echinococcus multilocularis	carbonyl reductase 1	0.0008	0.0053	0.0856
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0054	0.0619	0.3514
Echinococcus granulosus	3 ketodihydrosphingosine reductase	0.0008	0.0053	0.0301
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0054	0.0619	1
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Trypanosoma cruzi	3-ketoacyl-CoA reductase, putative	0.0008	0.0053	0.5
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0054	0.0619	1
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Loa Loa (eye worm)	oxidoreductase	0.0008	0.0053	0.0856
Brugia malayi	neuropeptide F receptor	0.0054	0.0619	1
Echinococcus multilocularis	dro:myosuppressin receptor	0.0054	0.0619	1
Echinococcus granulosus	serotonin receptor	0.0054	0.0619	0.3514
Brugia malayi	larval opioid receptor	0.0054	0.0619	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0054	0.0619	1
Trypanosoma cruzi	short chain dehydrogenase/reductase, putative	0.0008	0.0053	0.5
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0054	0.0619	1
Trypanosoma cruzi	short chain dehydrogenase/reductase, putative	0.0008	0.0053	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Schistosoma mansoni	biogenic amine receptor	0.0054	0.0619	0.3514
Trypanosoma cruzi	hypothetical protein, conserved	0.0008	0.0053	0.5
Trypanosoma brucei	beta-ketoacyl-ACP reductase 2	0.0008	0.0053	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0207	0.2469	0.2429
Loa Loa (eye worm)	G-protein coupled receptor	0.0054	0.0619	1
Echinococcus granulosus	g protein coupled receptor	0.0054	0.0619	0.3514
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Trypanosoma brucei	3-ketoacyl-CoA reductase, putative	0.0008	0.0053	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0054	0.0619	1
Onchocerca volvulus		0.0054	0.0619	1
Loa Loa (eye worm)	melatonin receptor type 1A	0.0054	0.0619	1
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Echinococcus multilocularis	transient receptor potential cation channel	0.0003	0.0003	0.0047
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0008	0.0053	0.5
Schistosoma mansoni	carbonyl reductase	0.0008	0.0053	0.0301
Brugia malayi	follicle stimulating hormone receptor	0.0054	0.0619	1
Echinococcus multilocularis	oxidoreductase	0.0008	0.0053	0.0856
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0054	0.0619	1
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Schistosoma mansoni	steroid dehydrogenase	0.0008	0.0053	0.0301
Schistosoma mansoni	steroid dehydrogenase	0.0008	0.0053	0.0301
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Brugia malayi	hypothetical protein	0.0054	0.0619	1
Echinococcus multilocularis	steroid dehydrogenase	0.0008	0.0053	0.0856
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Echinococcus multilocularis	serotonin receptor	0.0054	0.0619	1
Schistosoma mansoni	growth hormone secretagogue receptor	0.0054	0.0619	0.3514
Onchocerca volvulus		0.0054	0.0619	1
Trypanosoma cruzi	beta-ketoacyl-ACP reductase 2, putative	0.0008	0.0053	0.5
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0054	0.0619	0.3514
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0054	0.0619	0.3514
Brugia malayi	Hypothetical oxidoreductase F56D1.5	0.0008	0.0053	0.0813
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Brugia malayi	Dopamine receptor	0.0054	0.0619	1
Echinococcus granulosus	neuropeptide Y receptor	0.0054	0.0619	0.3514
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0054	0.0619	0.3514
Plasmodium falciparum	steroid dehydrogenase, putative	0.0008	0.0053	0.5
Toxoplasma gondii	oxidoreductase, putative	0.0008	0.0053	0.5
Echinococcus multilocularis	G protein coupled receptor 139	0.0054	0.0619	1
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0054	0.0619	1
Echinococcus granulosus	Dehydrogenase:reductase SDR family	0.0008	0.0053	0.0301
Echinococcus granulosus	carbonyl reductase 1	0.0008	0.0053	0.0301
Schistosoma mansoni	retinal dehydrogenase	0.0008	0.0053	0.0301
Echinococcus multilocularis	fmrfamide receptor	0.0054	0.0619	1
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0053	0.0856
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0053	0.0856
Brugia malayi	D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor	0.0008	0.0053	0.0813
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Trypanosoma cruzi	short chain dehydrogenase, putative	0.0008	0.0053	0.5
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0053	0.0856
Schistosoma mansoni	steroid dehydrogenase	0.0008	0.0053	0.0301
Brugia malayi	hypothetical protein	0.0054	0.0619	1
Trypanosoma brucei	short-chain dehydrogenase, putative	0.0008	0.0053	0.5
Leishmania major	short chain dehydrogenase/reductase, putative	0.0008	0.0053	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Loa Loa (eye worm)	TYRA-2 protein	0.0054	0.0619	1
Loa Loa (eye worm)	G-protein coupled receptor	0.0054	0.0619	1
Echinococcus granulosus	hypothetical protein	0.0008	0.0053	0.0301
Trichomonas vaginalis	conserved hypothetical protein	0.0207	0.2469	0.2429
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0054	0.0619	1
Schistosoma mansoni	biogenic amine receptor	0.0054	0.0619	0.3514
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Brugia malayi	dehydrogenases, short chain protein 9	0.0008	0.0053	0.0813
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0054	0.0619	1
Echinococcus granulosus	somatostatin receptor	0.0054	0.0619	0.3514
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0054	0.0619	0.3514
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0054	0.0619	1
Schistosoma mansoni	NADH dehydrogenase subunit 1	0.004	0.0446	0.2531
Schistosoma mansoni	steroid dehydrogenase	0.0008	0.0053	0.0301
Echinococcus multilocularis	g-protein coupled receptor	0.0054	0.0619	1
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Brugia malayi	RE15519p	0.0054	0.0619	1
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Loa Loa (eye worm)	oxidoreductase	0.0008	0.0053	0.0856
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0054	0.0619	0.3514
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Trichomonas vaginalis	conserved hypothetical protein	0.0207	0.2469	0.2429
Trypanosoma cruzi	short chain dehydrogenase, putative	0.0008	0.0053	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0054	0.0619	0.3514
Trichomonas vaginalis	FMN-dependent NADH-azoreductase, putative	0.0207	0.2469	0.2429
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.0828	1	1
Schistosoma mansoni	hypothetical protein	0.0054	0.0619	0.3514
Schistosoma mansoni	hypothetical protein	0.0054	0.0619	0.3514
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.0207	0.2469	0.2429
Onchocerca volvulus		0.004	0.0446	0.6943
Schistosoma mansoni	steroid dehydrogenase	0.0008	0.0053	0.0301
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0054	0.0619	0.3514
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Toxoplasma gondii	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.5
Onchocerca volvulus		0.0054	0.0619	1
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0054	0.0619	0.3514
Schistosoma mansoni	neuropeptide F-like receptor	0.0054	0.0619	0.3514
Mycobacterium ulcerans	NADH dehydrogenase subunit H	0.0148	0.1761	0.2608
Toxoplasma gondii	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.5
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0054	0.0619	0.3514
Trypanosoma cruzi	3-keto-dihydrosphingosine reductase	0.0008	0.0053	0.5
Leishmania major	hypothetical protein, conserved	0.0008	0.0053	0.5
Brugia malayi	hypothetical protein	0.004	0.0446	0.7191
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0054	0.0619	1
Echinococcus multilocularis	carbonyl reductase 1	0.0008	0.0053	0.0856
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Mycobacterium leprae	ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE	0.0008	0.0053	0.5
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0054	0.0619	1
Brugia malayi	Serotonin receptor	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Trypanosoma cruzi	hypothetical protein, conserved	0.0008	0.0053	0.5
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0054	0.0619	1
Schistosoma mansoni	amine GPCR	0.0054	0.0619	0.3514
Onchocerca volvulus		0.0054	0.0619	1
Onchocerca volvulus		0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0053	0.0856
Plasmodium falciparum	oxidoreductase, short-chain dehydrogenase family, putative	0.0008	0.0053	0.5
Echinococcus multilocularis	epidermal retinal dehydrogenase 2	0.0008	0.0053	0.0856
Loa Loa (eye worm)	neuropeptide F receptor	0.0054	0.0619	1
Leishmania major	3-oxoacyl-(acyl-carrier protein) reductase, putative	0.0008	0.0053	0.5
Echinococcus granulosus	allatostatin A receptor	0.0054	0.0619	0.3514
Echinococcus multilocularis	estradiol 17 beta dehydrogenase 12	0.0008	0.0053	0.0856
Echinococcus granulosus	NADH dehydrogenase subunit 1	0.0148	0.1761	1
Leishmania major	oxidoreductase-like protein	0.0008	0.0053	0.5
Onchocerca volvulus		0.0054	0.0619	1
Leishmania major	short chain dehydrogenase/reductase, putative	0.0008	0.0053	0.5
Schistosoma mansoni	neuropeptide f receptor 76f	0.0054	0.0619	0.3514
Echinococcus multilocularis	g protein coupled receptor	0.0054	0.0619	1
Trichomonas vaginalis	conserved hypothetical protein	0.0207	0.2469	0.2429
Echinococcus multilocularis	retinol dehydrogenase 13	0.0008	0.0053	0.0856
Trypanosoma brucei	beta-D-hydroxybutyrate dehydrogenase	0.0008	0.0053	0.5
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0054	0.0619	1
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0054	0.0619	1
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Trichomonas vaginalis	conserved hypothetical protein	0.0207	0.2469	0.2429
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Echinococcus multilocularis	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0008	0.0053	0.0856
Leishmania major	quinonoid dihydropteridine reductase	0.0008	0.0053	0.5
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0054	0.0619	0.3514
Schistosoma mansoni	myosin xvIII	0.0054	0.0619	0.3514
Schistosoma mansoni	3-keto-dihydrosphingosine reductase	0.0008	0.0053	0.0301
Toxoplasma gondii	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.5
Trypanosoma brucei	short-chain dehydrogenase, putative	0.0008	0.0053	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0054	0.0619	0.3514
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Onchocerca volvulus		0.0054	0.0619	1
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Mycobacterium tuberculosis	Probable oxidoreductase	0.0548	0.6601	1
Echinococcus multilocularis	carbonyl reductase 1	0.0008	0.0053	0.0856
Loa Loa (eye worm)	oxidoreductase	0.0008	0.0053	0.0856
Echinococcus granulosus	rhodopsin orphan GPCR	0.0054	0.0619	0.3514
Onchocerca volvulus		0.0054	0.0619	1
Brugia malayi	oxidoreductase	0.0008	0.0053	0.0813
Schistosoma mansoni	hypothetical protein	0.0148	0.1761	1
Toxoplasma gondii	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.5
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Loa Loa (eye worm)	oxidoreductase	0.0008	0.0053	0.0856
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0053	0.0856
Onchocerca volvulus		0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.0207	0.2469	0.2429
Brugia malayi	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0053	0.0856
Brugia malayi	Dopamine receptor protein 2	0.0054	0.0619	1
Schistosoma mansoni	carbonyl reductase	0.0008	0.0053	0.0301
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.0828	1	1
Entamoeba histolytica	hypothetical protein	0.0207	0.2469	1
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Onchocerca volvulus		0.0054	0.0619	1
Echinococcus granulosus	sex peptide receptor	0.0054	0.0619	0.3514
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Schistosoma mansoni	steroid dehydrogenase	0.0008	0.0053	0.0301
Brugia malayi	3-hydroxyacyl-CoA dehydrogenase type II	0.0008	0.0053	0.0813
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Brugia malayi	NADH dehydrogenase subunit 1	0.004	0.0446	0.7191
Loa Loa (eye worm)	dehydrogenase	0.0008	0.0053	0.0856
Mycobacterium leprae	Possible short-chain dehydrogenase EphD	0.0008	0.0053	0.5
Trypanosoma cruzi	oxidoreductase-like protein, putative	0.0008	0.0053	0.5
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Echinococcus granulosus	carbonyl reductase 1	0.0008	0.0053	0.0301
Echinococcus granulosus	epidermal retinal dehydrogenase 2	0.0008	0.0053	0.0301
Echinococcus multilocularis	conserved hypothetical protein	0.0008	0.0053	0.0856
Echinococcus multilocularis	neuropeptides capa receptor	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0054	0.0619	0.3514
Echinococcus multilocularis	orexin receptor type 2	0.0054	0.0619	1
Plasmodium vivax	steroid dehydrogenase, putative	0.0008	0.0053	0.5
Echinococcus granulosus	steroid dehydrogenase	0.0008	0.0053	0.0301
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0054	0.0619	0.3514
Brugia malayi	Dehydrogenases, short chain protein 30	0.0008	0.0053	0.0813
Leishmania major	dehydrogenase-like protein	0.0008	0.0053	0.5
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0054	0.0619	1
Schistosoma mansoni	short-chain dehydrogenase/reductase	0.0008	0.0053	0.0301
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0054	0.0619	0.3514
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Leishmania major	3-keto-dihydrosphingosine reductase	0.0008	0.0053	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.0813
Echinococcus granulosus	g protein coupled receptor	0.0054	0.0619	0.3514
Mycobacterium leprae	Probable oxidoreductase	0.0008	0.0053	0.5
Mycobacterium leprae	PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE	0.0008	0.0053	0.5
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0054	0.0619	0.3514
Brugia malayi	G-protein coupled receptor	0.0054	0.0619	1
Echinococcus multilocularis	neuropeptide receptor A26	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0053	0.0856
Toxoplasma gondii	2,4-dienoyl CoA reductase 2, peroxisomal family protein	0.0008	0.0053	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0008	0.0053	0.0301
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Toxoplasma gondii	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0008	0.0053	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0828	1	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Trypanosoma brucei	short-chain dehydrogenase, putative	0.0008	0.0053	0.5
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Brugia malayi	neuropeptide F receptor	0.0054	0.0619	1
Trichomonas vaginalis	conserved hypothetical protein	0.0207	0.2469	0.2429
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0054	0.0619	0.3514
Echinococcus multilocularis	neuropeptides capa receptor	0.0054	0.0619	1
Brugia malayi	Serotonin receptor	0.0054	0.0619	1
Trypanosoma cruzi	NAD(P)-dependent oxidoreductase, putative	0.0008	0.0053	0.5
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0054	0.0619	0.3514
Echinococcus multilocularis	fmrfamide receptor	0.0054	0.0619	1
Echinococcus granulosus	carbonyl reductase 1	0.0008	0.0053	0.0301
Echinococcus granulosus	7TM GPCR rhodopsin	0.0054	0.0619	0.3514
Echinococcus multilocularis	transient receptor potential cation channel	0.0003	0.0003	0.0047
Echinococcus granulosus	hypothetical protein	0.0008	0.0053	0.0301
Echinococcus granulosus	biogenic amine 5HT receptor	0.0054	0.0619	0.3514
Schistosoma mansoni	steroid dehydrogenase	0.0008	0.0053	0.0301
Brugia malayi	NADH dehydrogenase subunit 1, identical	0.004	0.0446	0.7191
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0053	0.0856
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0053	0.0856
Schistosoma mansoni	amine GPCR	0.0054	0.0619	0.3514
Echinococcus granulosus	g protein coupled receptor	0.0054	0.0619	0.3514
Loa Loa (eye worm)	neuropeptide F receptor	0.0054	0.0619	1
Giardia lamblia	NADPH oxidoreductase, putative	0.0828	1	1
Leishmania major	quinonoid dihydropteridine reductase	0.0008	0.0053	0.5
Trypanosoma cruzi	beta-ketoacyl-ACP reductase 2, putative	0.0008	0.0053	0.5
Echinococcus multilocularis	allatostatin A receptor	0.0054	0.0619	1
Echinococcus granulosus	WW domain containing oxidoreductase	0.0008	0.0053	0.0301
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0054	0.0619	0.3514
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0054	0.0619	0.3514
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.0828	1	1
Echinococcus granulosus	7tm_1 domain containing protein	0.0054	0.0619	0.3514
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Mycobacterium ulcerans	short chain dehydrogenase	0.0548	0.6601	1
Brugia malayi	Dopamine receptor protein 1	0.0054	0.0619	1
Trichomonas vaginalis	modulator of drug activity B, putative	0.0207	0.2469	0.2429
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Leishmania major	hypothetical protein, conserved	0.0008	0.0053	0.5
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Loa Loa (eye worm)	NADH dehydrogenase subunit 1	0.004	0.0446	0.7204
Loa Loa (eye worm)	oxidoreductase	0.0008	0.0053	0.0856
Leishmania major	hypothetical protein, conserved	0.0008	0.0053	0.5
Schistosoma mansoni	amine GPCR	0.0054	0.0619	0.3514
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0053	0.0856
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Echinococcus granulosus	neuropeptides capa receptor	0.0054	0.0619	0.3514
Brugia malayi	hypothetical protein	0.0054	0.0619	1
Mycobacterium ulcerans	formate hydrogenlyase HycD	0.004	0.0446	0.06
Brugia malayi	Retinol dehydrogenase 12	0.0008	0.0053	0.0813
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0619	1
Mycobacterium tuberculosis	Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H)	0.0148	0.1761	0.2608
Trypanosoma brucei	oxidoreductase-like protein	0.0008	0.0053	0.5
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0054	0.0619	1
Echinococcus granulosus	oxidoreductase	0.0008	0.0053	0.0301

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 884078