TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 370.203 | Formula: C16H12BrN5O
H donors: 2 H acceptors: 4 LogP: 3.48 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: Brc1ccc(cc1)C=NNc1nnc(c(n1)O)c1ccccc1
InChi: 1S/C16H12BrN5O/c17-13-8-6-11(7-9-13)10-18-21-16-19-15(23)14(20-22-16)12-4-2-1-3-5-12/h1-10H,(H2,19,21,22,23)/b18-10+
InChiKey: OLCPNOMOUQRVCU-VCHYOVAHSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	amine GPCR	0.0116	0.2087	0.2087
Echinococcus granulosus	somatostatin receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0116	0.2087	0.2087
Brugia malayi	hypothetical protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	AMP deaminase	0.0126	0.239	0.239
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	P2X receptor subunit	0.0266	0.6461	0.6461
Echinococcus granulosus	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	hypothetical protein	0.0116	0.2087	0.2087
Brugia malayi	sulfakinin receptor protein	0.0116	0.2087	0.2087
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	adenosine deaminase	0.0388	1	1
Echinococcus granulosus	neuropeptide receptor	0.0116	0.2087	0.2087
Plasmodium falciparum	adenosine deaminase	0.0388	1	1
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0116	0.2087	0.2087
Brugia malayi	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus granulosus	dro:myosuppressin receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Loa Loa (eye worm)	TYRA-2 protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	G-protein coupled receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	myosin xvIII	0.0116	0.2087	0.2087
Echinococcus multilocularis	neuropeptide Y receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	neuropeptides capa receptor	0.0116	0.2087	0.2087
Brugia malayi	Dopamine receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	P2X receptor subunit	0.0266	0.6461	0.6461
Brugia malayi	follicle stimulating hormone receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0261	0.6323	0.6323
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus multilocularis	somatostatin receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	g protein coupled receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	amine GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0116	0.2087	0.2087
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	hypothetical protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0116	0.2087	0.2087
Loa Loa (eye worm)	melatonin receptor type 1A	0.0116	0.2087	0.2087
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0116	0.2087	0.2087
Trypanosoma brucei	AMP deaminase, putative	0.0126	0.239	0.5
Echinococcus multilocularis	neuropeptide Y receptor	0.0116	0.2087	0.2087
Brugia malayi	AKH receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Brugia malayi	hypothetical protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0388	1	1
Schistosoma mansoni	hypothetical protein	0.0116	0.2087	0.2087
Entamoeba histolytica	adenosine deaminase, putative	0.0388	1	1
Echinococcus granulosus	adenosine deaminase	0.0388	1	1
Loa Loa (eye worm)	hypothetical protein	0.0261	0.6323	0.6323
Brugia malayi	hypothetical protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	neuropeptide receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	neuropeptide Y receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	p2X purinoceptor 4	0.0266	0.6461	0.6461
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0116	0.2087	0.2087
Brugia malayi	Serotonin receptor	0.0116	0.2087	0.2087
Mycobacterium tuberculosis	Probable adenosine deaminase Add (adenosine aminohydrolase)	0.0388	1	0.5
Echinococcus multilocularis	serotonin receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0116	0.2087	0.2087
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	opsin-like receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	G protein coupled receptor 139	0.0116	0.2087	0.2087
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0261	0.6323	0.6323
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus multilocularis	g protein coupled receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	neuropeptide s receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	7TM GPCR rhodopsin	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus granulosus	fmrfamide receptor	0.0116	0.2087	0.2087
Brugia malayi	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	P2X receptor subunit	0.0132	0.2555	0.2555
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0116	0.2087	0.2087
Echinococcus multilocularis	AMP deaminase 2	0.0126	0.239	0.239
Echinococcus granulosus	neuropeptide receptor	0.0116	0.2087	0.2087
Trypanosoma brucei	adenosine monophosphate deaminase, putative	0.0126	0.239	0.5
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0261	0.6323	0.6323
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0116	0.2087	0.2087
Mycobacterium ulcerans	adenosine deaminase	0.0388	1	0.5
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Trypanosoma cruzi	AMP deaminase 2, putative	0.0126	0.239	0.5
Schistosoma mansoni	opsin-like receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus granulosus	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	neuropeptide FF receptor 2	0.0116	0.2087	0.2087
Brugia malayi	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus granulosus	G protein coupled receptor 139	0.0116	0.2087	0.2087
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0116	0.2087	0.2087
Echinococcus multilocularis	fmrfamide receptor	0.0116	0.2087	0.2087
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0126	0.239	0.239
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Trypanosoma brucei	AMP deaminase, putative	0.0126	0.239	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0116	0.2087	0.2087
Brugia malayi	Serotonin receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus granulosus	allatostatin A receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0116	0.2087	0.2087
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0116	0.2087	0.2087
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0116	0.2087	0.2087
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Brugia malayi	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	neuropeptide F-like receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Entamoeba histolytica	adenosine deaminase, putative	0.0388	1	1
Schistosoma mansoni	neuropeptide F-like receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0116	0.2087	0.2087
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	histamine h1 receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	neuropeptide receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0116	0.2087	0.2087
Brugia malayi	adenosine monophosphate deaminase	0.0126	0.239	0.239
Brugia malayi	G-protein coupled receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	adenosine deaminase-related	0.0388	1	1
Echinococcus multilocularis	p2X purinoceptor 4	0.0266	0.6461	0.6461
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0116	0.2087	0.2087
Toxoplasma gondii	Adenosine/AMP deaminase domain-containing protein	0.0388	1	1
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	biogenic amine receptor	0.0116	0.2087	0.2087
Brugia malayi	G protein-coupled receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	G-protein coupled receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0116	0.2087	0.2087
Echinococcus granulosus	g protein coupled receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Brugia malayi	G protein-coupled receptor F59B2.13	0.0116	0.2087	0.2087
Trypanosoma cruzi	AMP deaminase, putative	0.0126	0.239	0.5
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0116	0.2087	0.2087
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0116	0.2087	0.2087
Brugia malayi	neuropeptide F receptor	0.0116	0.2087	0.2087
Trypanosoma cruzi	AMP deaminase, putative	0.0126	0.239	0.5
Echinococcus granulosus	p2X purinoceptor 4	0.0266	0.6461	0.6461
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	growth hormone secretagogue receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0116	0.2087	0.2087
Echinococcus granulosus	neuropeptide Y receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus multilocularis	allatostatin A receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	serotonin receptor	0.0116	0.2087	0.2087
Brugia malayi	RE15519p	0.0116	0.2087	0.2087
Echinococcus granulosus	serotonin receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	biogenic amine receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	tm gpcr rhodopsin	0.0116	0.2087	0.2087
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	AMP deaminase	0.0126	0.239	0.239
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	g protein coupled receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	fmrfamide receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	neuropeptide s receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0116	0.2087	0.2087
Trypanosoma cruzi	adenosine monophosphate deaminase-like protein, putative	0.0126	0.239	0.5
Schistosoma mansoni	amine GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	biogenic amine receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	AMP deaminase 2	0.0126	0.239	0.239
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus granulosus	biogenic amine 5HT receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	P2X receptor subunit	0.0132	0.2555	0.2555
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0116	0.2087	0.2087
Brugia malayi	Melatonin receptor type 1A	0.0116	0.2087	0.2087
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0116	0.2087	0.2087
Schistosoma mansoni	opsin-like receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Brugia malayi	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus granulosus	tm gpcr rhodopsin	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Echinococcus multilocularis	dro:myosuppressin receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0116	0.2087	0.2087
Brugia malayi	putative neuropeptide receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	p2X purinoceptor 4	0.0266	0.6461	0.6461
Echinococcus multilocularis	neuropeptide receptor A26	0.0116	0.2087	0.2087
Echinococcus granulosus	neuropeptide receptor A26	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0116	0.2087	0.2087
Echinococcus multilocularis	neuropeptide receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0116	0.2087	0.2087
Echinococcus granulosus	g protein coupled receptor	0.0116	0.2087	0.2087
Leishmania major	adenine aminohydrolase	0.0388	1	1
Echinococcus granulosus	sex peptide receptor	0.0116	0.2087	0.2087
Onchocerca volvulus	AMP deaminase 2 homolog	0.0126	0.239	0.0382
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	neuropeptide receptor	0.0116	0.2087	0.2087
Brugia malayi	Dopamine receptor protein 2	0.0116	0.2087	0.2087
Brugia malayi	ORL1-like opioid receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0116	0.2087	0.2087
Trypanosoma cruzi	AMP deaminase, putative	0.0126	0.239	0.5
Brugia malayi	neuropeptide F receptor	0.0116	0.2087	0.2087
Mycobacterium leprae	Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE)	0.0388	1	0.5
Trichomonas vaginalis	adenosine deaminase, putative	0.0388	1	0.5
Onchocerca volvulus	Adenosine deaminase homolog	0.0388	1	1
Echinococcus granulosus	g-protein coupled receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	amine GPCR	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0116	0.2087	0.2087
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus multilocularis	sex peptide receptor	0.0116	0.2087	0.2087
Plasmodium vivax	adenosine deaminase, putative	0.0388	1	1
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Trypanosoma cruzi	AMP deaminase, putative	0.0126	0.239	0.5
Toxoplasma gondii	Adenosine/AMP deaminase domain-containing protein	0.0388	1	1
Schistosoma mansoni	adenoreceptor	0.0116	0.2087	0.2087
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0116	0.2087	0.2087
Echinococcus granulosus	tm gpcr rhodopsin	0.0116	0.2087	0.2087
Echinococcus granulosus	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	neuropeptide receptor	0.0116	0.2087	0.2087
Trypanosoma cruzi	adenosine monophosphate deaminase, putative	0.0126	0.239	0.5
Loa Loa (eye worm)	neuropeptide F receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Brugia malayi	putative neuropeptide receptor NPR1	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Trypanosoma brucei	AMP deaminase, putative	0.0126	0.239	0.5
Schistosoma mansoni	amine GPCR	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	neuropeptide receptor	0.0116	0.2087	0.2087
Echinococcus granulosus	7tm_1 domain containing protein	0.0116	0.2087	0.2087
Echinococcus granulosus	neuropeptides capa receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Brugia malayi	larval opioid receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	neuropeptides capa receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Echinococcus multilocularis	neuropeptides capa receptor	0.0116	0.2087	0.2087
Brugia malayi	GnHR receptor homolog	0.0116	0.2087	0.2087
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Trichomonas vaginalis	adenosine deaminase, putative	0.0388	1	0.5
Echinococcus granulosus	g protein coupled receptor	0.0116	0.2087	0.2087
Brugia malayi	G-protein coupled receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	neuropeptide f receptor 76f	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Trypanosoma cruzi	AMP deaminase, putative	0.0126	0.239	0.5
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Schistosoma mansoni	adenosine deaminase	0.0388	1	1
Brugia malayi	hypothetical protein	0.0116	0.2087	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0116	0.2087	0.2087
Onchocerca volvulus		0.0126	0.239	0.0382
Echinococcus multilocularis	orexin receptor type 2	0.0116	0.2087	0.2087
Brugia malayi	hypothetical protein	0.0116	0.2087	0.2087
Treponema pallidum	adenosine deaminase	0.0388	1	0.5
Echinococcus multilocularis	g-protein coupled receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0116	0.2087	0.2087
Echinococcus multilocularis	p2X purinoceptor 4	0.0266	0.6461	0.6461
Brugia malayi	Dopamine receptor protein 1	0.0116	0.2087	0.2087
Echinococcus granulosus	orexin receptor type 2	0.0116	0.2087	0.2087
Echinococcus granulosus	biogenic amine 5HT receptor	0.0116	0.2087	0.2087
Loa Loa (eye worm)	neuropeptide F receptor	0.0116	0.2087	0.2087
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0116	0.2087	0.2087
Echinococcus multilocularis	p2X purinoceptor 4	0.0266	0.6461	0.6461
Echinococcus granulosus	rhodopsin orphan GPCR	0.0116	0.2087	0.2087

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 884158