Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0068 | 0.0151 | 0.0232 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0068 | 0.0151 | 0.0232 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0068 | 0.0151 | 0.0232 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0068 | 0.0151 | 0.0164 |
Brugia malayi | Carboxylesterase family protein | 0.0404 | 0.6494 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0068 | 0.0151 | 0.0232 |
Echinococcus multilocularis | neuroligin | 0.0068 | 0.0151 | 0.0232 |
Onchocerca volvulus | 0.0068 | 0.0151 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0068 | 0.0151 | 0.0164 |
Onchocerca volvulus | 0.0068 | 0.0151 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0068 | 0.0151 | 0.0232 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0068 | 0.0151 | 0.0232 |
Onchocerca volvulus | 0.0068 | 0.0151 | 0.5 | |
Onchocerca volvulus | 0.0068 | 0.0151 | 0.5 | |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0068 | 0.0151 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0068 | 0.0151 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0068 | 0.0151 | 0.0232 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0068 | 0.0151 | 0.0151 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0404 | 0.6494 | 1 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.059 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0404 | 0.6494 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0404 | 0.6494 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0068 | 0.0151 | 0.0232 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0068 | 0.0151 | 0.0232 |
Schistosoma mansoni | gliotactin | 0.0068 | 0.0151 | 0.0232 |
Echinococcus multilocularis | acetylcholinesterase | 0.0404 | 0.6494 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0 | 0.5 |
Schistosoma mansoni | acetylcholinesterase | 0.0068 | 0.0151 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.0404 | 0.6494 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0404 | 0.6494 | 1 |
Echinococcus granulosus | neuroligin | 0.0068 | 0.0151 | 0.0232 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0068 | 0.0151 | 0.0232 |
Onchocerca volvulus | 0.0068 | 0.0151 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0068 | 0.0151 | 0.0164 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0404 | 0.6494 | 1 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0548 | 0.9216 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0404 | 0.6494 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0068 | 0.0151 | 0.0232 |
Echinococcus multilocularis | acetylcholinesterase | 0.0404 | 0.6494 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0404 | 0.6494 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0404 | 0.6494 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0404 | 0.6494 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.