Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | dna polymerase eta | 0.0022 | 1 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 1 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 1 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0022 | 1 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0022 | 1 | 0.5 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0022 | 1 | 0.5 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0022 | 1 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 1 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.0022 | 1 | 0.5 |
Schistosoma mansoni | DNA polymerase eta | 0.0022 | 1 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0022 | 1 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0022 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 1 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0022 | 1 | 1 |
Trypanosoma brucei | unspecified product | 0.0022 | 1 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0022 | 1 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0022 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 1 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0022 | 1 | 0.5 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0022 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 1 | 0.5 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0022 | 1 | 0.5 |
Echinococcus granulosus | dna polymerase kappa | 0.0022 | 1 | 0.5 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0022 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 1 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0022 | 1 | 0.5 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0022 | 1 | 0.5 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0022 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 1 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0022 | 1 | 0.5 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0022 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.