TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 468.456 | Formula: C20H22F6N2O2S
H donors: 2 H acceptors: 3 LogP: 5.51 Rotable bonds: 11
Rule of 5 violations (Lipinski): 1
SMILES: OCC(CCCNC(=O)c1csc(n1)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)(C)C
InChi: 1S/C20H22F6N2O2S/c1-18(2,11-29)4-3-5-27-17(30)15-10-31-16(28-15)8-12-6-13(19(21,22)23)9-14(7-12)20(24,25)26/h6-7,9-10,29H,3-5,8,11H2,1-2H3,(H,27,30)
InChiKey: GBLSFGHIYLYSNB-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0023	0.0069	0.0069
Schistosoma mansoni	cathepsin F (C01 family)	0.0759	0.6614	0.6614
Schistosoma mansoni	neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule	0.0018	0.0023	0.0023
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0041	0.0231	0.0231
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0022	0.0056	0.0056
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0038	0.0198	0.0198
Schistosoma mansoni	cathepsin s	0.038	0.3248	0.3248
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Leishmania major	cathepsin L-like protease	0.1139	1	1
Echinococcus multilocularis	Immunoglobulin	0.0031	0.0139	0.0139
Plasmodium falciparum	dipeptidyl aminopeptidase 2	0.0417	0.3568	0.3553
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0018	0.0023	0.0023
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Trypanosoma cruzi	hexose transporter, putative	0.0038	0.0199	0.0058
Plasmodium vivax	unspecified product	0.038	0.3248	0.3231
Schistosoma mansoni	cell adhesion molecule	0.0018	0.0023	0.0023
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Toxoplasma gondii	facilitative glucose transporter GT1	0.0223	0.1848	0.1802
Schistosoma mansoni	roundabout	0.0018	0.0023	0.0023
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.1139	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1139	1	1
Onchocerca volvulus		0.1139	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.1139	1	1
Plasmodium falciparum	hexose transporter	0.0223	0.1848	0.1829
Leishmania major	glucose transporter, lmgt3	0.0069	0.0478	0.0424
Schistosoma mansoni	glucose transport protein	0.0223	0.1848	0.1848
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0212	0.1752	0.1705
Brugia malayi	Major Facilitator Superfamily protein	0.0031	0.0141	0.0141
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0759	0.6614	0.6595
Leishmania major	4-coumarate:coa ligase-like protein	0.0024	0.0079	0.0022
Trypanosoma brucei	glucose transporter, putative	0.0069	0.0478	0.0424
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Trichomonas vaginalis	CMGC family protein kinase	0.0104	0.0788	0.0736
Trypanosoma cruzi	cysteine peptidase, putative	0.1139	1	1
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.029	0.2441	0.2423
Onchocerca volvulus		0.0031	0.0141	0.0118
Mycobacterium tuberculosis	Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter)	0.0031	0.0141	1
Loa Loa (eye worm)	hypothetical protein	0.038	0.3248	0.3248
Echinococcus granulosus	cathepsin b	0.0212	0.1752	0.1752
Echinococcus granulosus	roundabout 2	0.0049	0.03	0.03
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Brugia malayi	Sugar transporter family protein	0.0031	0.0141	0.0141
Onchocerca volvulus		0.1139	1	1
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0212	0.1752	0.1752
Onchocerca volvulus	Cathepsin L homolog	0.1139	1	1
Schistosoma mansoni	cathepsin F (C01 family)	0.1139	1	1
Trypanosoma cruzi	cysteine proteinase, putative	0.0593	0.5137	0.5068
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0024
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0593	0.5137	0.5137
Echinococcus multilocularis	neuroglian	0.0039	0.021	0.021
Schistosoma mansoni	serine/threonine protein kinase	0.0022	0.0056	0.0056
Entamoeba histolytica	cysteine proteinase, putative	0.0593	0.5137	0.511
Trypanosoma cruzi	hexose transporter, putative	0.0069	0.0478	0.0342
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1139	1	1
Entamoeba histolytica	cell division protein kinase 2, putative	0.0094	0.0697	0.0644
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0212	0.1752	0.1752
Giardia lamblia	Cysteine protease	0.0212	0.1752	0.47
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Onchocerca volvulus		0.0031	0.0141	0.0118
Entamoeba histolytica	cysteine protease, putative	0.0212	0.1752	0.1705
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Trypanosoma brucei	glucose transporter, putative	0.0069	0.0478	0.0424
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0223	0.1848	0.1848
Brugia malayi	Calcium/calmodulin-dependent protein kinase type II alpha chain	0.0022	0.0056	0.0056
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1139	1	1
Onchocerca volvulus		0.0031	0.0141	0.0118
Giardia lamblia	Encystation-specific protease	0.029	0.2441	0.6711
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0212	0.1752	0.1752
Echinococcus multilocularis	hemicentin 1	0.0018	0.0023	0.0023
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0212	0.1752	0.1705
Trichomonas vaginalis	conserved hypothetical protein	0.0223	0.1848	0.1802
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0212	0.1752	0.1752
Plasmodium vivax	unspecified product	0.0212	0.1752	0.1732
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0018	0.0023	0.0023
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0593	0.5137	0.511
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0069	0.0478	0.0424
Giardia lamblia	Cathepsin L-like protease	0.0212	0.1752	0.47
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0104	0.0788	0.0788
Schistosoma mansoni	sugar transporter	0.0031	0.0141	0.0141
Entamoeba histolytica	hypothetical protein	0.0212	0.1752	0.1705
Plasmodium vivax	unspecified product	0.0593	0.5137	0.5126
Leishmania major	cathepsin L-like protease	0.1139	1	1
Plasmodium vivax	serine-repeat antigen 3 (SERA)	0.0212	0.1752	0.1732
Giardia lamblia	Cathepsin L-like protease	0.0212	0.1752	0.47
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Brugia malayi	Papain family cysteine protease containing protein	0.1139	1	1
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0041	0.0231	0.0231
Onchocerca volvulus		0.0031	0.0141	0.0118
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Brugia malayi	Papain family cysteine protease containing protein	0.0593	0.5137	0.5137
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0024	0.0079	0.0022
Schistosoma mansoni	protein kinase	0.0022	0.0056	0.0056
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.0212	0.1752	0.1752
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0212	0.1752	0.1705
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0024	0.0079	0.5039
Trypanosoma brucei	protein kinase, putative	0.0104	0.0788	0.0736
Onchocerca volvulus		0.0031	0.0141	0.0118
Trichomonas vaginalis	CMGC family protein kinase	0.0094	0.0697	0.0644
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0024	0.0079	0.5039
Brugia malayi	AMP-binding enzyme family protein	0.0024	0.0079	0.0079
Entamoeba histolytica	cysteine proteinase 1, putative	0.0593	0.5137	0.511
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0034	0.0163	0.0163
Echinococcus granulosus	cathepsin l1	0.0759	0.6614	0.6614
Schistosoma mansoni	cathepsin F (C01 family)	0.1139	1	1
Loa Loa (eye worm)	hypothetical protein	0.0212	0.1752	0.1752
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0049	0.0298	0.0298
Loa Loa (eye worm)	ctsf protein	0.1139	1	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0041	0.0231	0.0231
Plasmodium falciparum	serine repeat antigen 4	0.0212	0.1752	0.1732
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0024	0.0079	0.0022
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0079	0.0079
Brugia malayi	cathepsin L-like cysteine proteinase	0.0212	0.1752	0.1752
Schistosoma mansoni	cell adhesion molecule	0.0041	0.0229	0.0229
Trypanosoma cruzi	cysteine peptidase, putative	0.1139	1	1
Loa Loa (eye worm)	hypothetical protein	0.0212	0.1752	0.1752
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0022	0.0056	0.0056
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.038	0.3248	0.3248
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0212	0.1752	0.1752
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1139	1	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0507	0.4373	0.4373
Echinococcus multilocularis	protein kinase shaggy	0.0104	0.0788	0.0788
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0079	0.0079
Plasmodium falciparum	cysteine proteinase falcipain 3	0.1139	1	1
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Plasmodium falciparum	dipeptidyl aminopeptidase 1	0.0417	0.3568	0.3553
Loa Loa (eye worm)	hypothetical protein	0.0212	0.1752	0.1752
Trypanosoma brucei	glucose transporter, putative	0.0069	0.0478	0.0424
Brugia malayi	hypothetical protein	0.0031	0.0141	0.0141
Onchocerca volvulus		0.1139	1	1
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0223	0.1848	0.1848
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0018	0.0023	0.0023
Onchocerca volvulus		0.0104	0.0788	0.0766
Plasmodium falciparum	calcium-dependent protein kinase 2	0.0022	0.0056	0.0033
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0023	0.0023
Entamoeba histolytica	cysteine proteinase, putative	0.1139	1	1
Echinococcus granulosus	cathepsin L	0.0212	0.1752	0.1752
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0212	0.1752	0.1752
Loa Loa (eye worm)	hypothetical protein	0.0034	0.016	0.016
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0212	0.1752	0.1705
Echinococcus granulosus	cysteine protease	0.0593	0.5137	0.5137
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1139	1	1
Entamoeba histolytica	acyl-coA synthetase, putative	0.0024	0.0079	0.0022
Echinococcus granulosus	Sugar transporter ERD6 protein	0.0031	0.0141	0.0141
Entamoeba histolytica	cysteine proteinase, putative	0.0593	0.5137	0.511
Entamoeba histolytica	protein kinase domain containing protein	0.0104	0.0788	0.0736
Loa Loa (eye worm)	CMGC/CDK/CDK5 protein kinase	0.0094	0.0697	0.0697
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0212	0.1752	0.1752
Leishmania major	glucose transporter/membrane transporter D2, putative	0.0069	0.0478	0.0424
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0041	0.0231	0.0231
Trichomonas vaginalis	sugar transport protein, putative	0.0031	0.0141	0.0085
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0212	0.1752	0.1705
Onchocerca volvulus		0.0031	0.0141	0.0118
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0018	0.0023	0.0023
Giardia lamblia	Cathepsin B precursor	0.0212	0.1752	0.47
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1139	1	1
Schistosoma mansoni	serine/threonine protein kinase	0.0094	0.0697	0.0697
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1139	1	1
Onchocerca volvulus		0.1139	1	1
Brugia malayi	Cathepsin L-like precursor	0.0759	0.6614	0.6614
Giardia lamblia	Cathepsin L precursor	0.0212	0.1752	0.47
Echinococcus multilocularis	roundabout 2	0.0049	0.03	0.03
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0229	0.0229
Trichomonas vaginalis	conserved hypothetical protein	0.0212	0.1752	0.1705
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0024	0.0079	0.5
Onchocerca volvulus	Cathepsin F homolog	0.1139	1	1
Plasmodium vivax	serine-repeat antigen (SERA)	0.0212	0.1752	0.1732
Entamoeba histolytica	cysteine protease, putative	0.0212	0.1752	0.1705
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0024	0.0079	0.5
Onchocerca volvulus		0.0031	0.0141	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0212	0.1752	0.1752
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0049	0.0298	0.0298
Brugia malayi	Papain family cysteine protease containing protein	0.0212	0.1752	0.1752
Leishmania major	myo-inositol/proton symporter (MIT)	0.0031	0.0141	0.0085
Brugia malayi	cathepsin L-like precursor	0.0759	0.6614	0.6614
Echinococcus multilocularis	cathepsin L cysteine protease	0.1139	1	1
Onchocerca volvulus		0.0462	0.3971	0.3957
Trichomonas vaginalis	Clan CA, family C1, cathepsin H-like cysteine peptidase	0.0212	0.1752	0.1705
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.1139	1	1
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Trypanosoma brucei	glucose transporter, putative	0.0069	0.0478	0.0424
Echinococcus granulosus	neuroglian	0.0018	0.0023	0.0023
Plasmodium falciparum	serine repeat antigen 7	0.0212	0.1752	0.1732
Trypanosoma brucei	myo-inositol/proton symporter (MIT)	0.0031	0.0141	0.0085
Plasmodium vivax	glycogen synthase kinase 3, putative	0.0104	0.0788	0.0766
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1139	1	1
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0018	0.0024	0.07
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0212	0.1752	0.1705
Giardia lamblia	Cathepsin B precursor	0.0212	0.1752	0.47
Toxoplasma gondii	sugar transporter ST3	0.0031	0.0141	0.0085
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0139	0.0139
Schistosoma mansoni	sugar transporter	0.0031	0.0141	0.0141
Echinococcus granulosus	cyclin dependent kinase	0.0094	0.0697	0.0697
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0018	0.0023	0.0023
Giardia lamblia	Cathepsin B precursor	0.0212	0.1752	0.47
Leishmania major	glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270	0.0104	0.0788	0.0736
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0212	0.1752	0.1634
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0023	0.0023
Echinococcus multilocularis	cyclin dependent kinase 5	0.0094	0.0697	0.0697
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1139	1	1
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0022	0.0056	0.0056
Trypanosoma cruzi	hexose transporter	0.0069	0.0478	0.0342
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0212	0.1752	0.1705
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0024	0.0079	0.4666
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1139	1	1
Schistosoma mansoni	vesicular amine transporter	0.0031	0.0139	0.0139
Trichomonas vaginalis	conserved hypothetical protein	0.0069	0.0478	0.0424
Leishmania major	cysteine peptidase A (CPA)	0.1139	1	1
Schistosoma mansoni	cell adhesion molecule	0.0018	0.0023	0.0023
Brugia malayi	cathepsin F-like cysteine proteinase	0.038	0.3248	0.3248
Schistosoma mansoni	protein kinase	0.0022	0.0056	0.0056
Loa Loa (eye worm)	hypothetical protein	0.0759	0.6614	0.6614
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0041	0.0231	0.0231
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0031	0.0139	0.0139
Echinococcus multilocularis	solute carrier family 22	0.0031	0.0141	0.0141
Loa Loa (eye worm)	calcium/calmodulin-dependent protein kinase ID	0.0022	0.0056	0.0056
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1139	1	1
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.0417	0.3568	1
Brugia malayi	AMP-binding enzyme family protein	0.0024	0.0079	0.0079
Giardia lamblia	Cathepsin B precursor	0.0212	0.1752	0.47
Entamoeba histolytica	papain family cysteine protease domain containing protein	0.0212	0.1752	0.1705
Leishmania major	cathepsin L-like protease	0.1139	1	1
Trichomonas vaginalis	myo-inositol transporter, putative	0.0031	0.0141	0.0085
Entamoeba histolytica	cysteine proteinase, putative	0.1139	1	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0041	0.0231	0.0231
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0094	0.0697	0.0697
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0023	0.0023
Plasmodium falciparum	calcium-dependent protein kinase 1	0.0022	0.0056	0.0033
Brugia malayi	Papain family cysteine protease containing protein	0.0593	0.5137	0.5137
Echinococcus granulosus	neuroglian	0.0039	0.021	0.021
Onchocerca volvulus		0.0031	0.0141	0.0118
Plasmodium vivax	vivapain-3	0.0593	0.5137	0.5126
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0593	0.5137	0.511
Brugia malayi	Sugar transporter family protein	0.0223	0.1848	0.1848
Schistosoma mansoni	hypothetical protein	0.0034	0.016	0.016
Trypanosoma brucei	cdc2-related kinase 1	0.0094	0.0697	0.0644
Giardia lamblia	Cathepsin L precursor	0.0212	0.1752	0.47
Schistosoma mansoni	sugar transporter	0.0031	0.0141	0.0141
Onchocerca volvulus		0.1139	1	1
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Loa Loa (eye worm)	hypothetical protein	0.0212	0.1752	0.1752
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0056	0.0056
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1139	1	1
Onchocerca volvulus		0.0031	0.0141	0.0118
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.1139	1	1
Echinococcus multilocularis	glycogen synthase kinase 3 beta	0.0104	0.0788	0.0788
Onchocerca volvulus		0.0031	0.0141	0.0118
Echinococcus multilocularis	hemicentin 1	0.0018	0.0023	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0139	0.0139
Trypanosoma cruzi	cdc2-related kinase 1	0.0094	0.0697	0.0564
Brugia malayi	Papain family cysteine protease containing protein	0.0212	0.1752	0.1752
Echinococcus granulosus	cathepsin L cysteine protease	0.0593	0.5137	0.5137
Toxoplasma gondii	transporter, major facilitator family protein	0.0031	0.0141	0.0085
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.0018	0.0023	0.0023
Trichomonas vaginalis	sugar transporter, putative	0.0069	0.0478	0.0424
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0104	0.0788	0.0788
Plasmodium vivax	serine-repeat antigen 5 (SERA)	0.0212	0.1752	0.1732
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1139	1	1
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0094	0.0697	0.0697
Echinococcus multilocularis	cyclin dependent kinase 1	0.0094	0.0697	0.0697
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Plasmodium vivax	hexose transporter	0.0223	0.1848	0.1829
Giardia lamblia	Cysteine protease	0.0212	0.1752	0.47
Trypanosoma brucei	sugar transporter, putative	0.0031	0.0141	0.0085
Brugia malayi	Papain family cysteine protease containing protein	0.0212	0.1752	0.1752
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Mycobacterium ulcerans	acyl-CoA synthetase	0.0024	0.0079	0.4666
Echinococcus multilocularis	solute carrier family 22	0.0031	0.0141	0.0141
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.1139	1	1
Trypanosoma cruzi	cdc2-related kinase 1	0.0094	0.0697	0.0564
Onchocerca volvulus		0.1139	1	1
Echinococcus granulosus	solute carrier family 22	0.0031	0.0141	0.0141
Plasmodium falciparum	calcium-dependent protein kinase 4	0.0022	0.0056	0.0033
Leishmania major	cathepsin L-like protease	0.1139	1	1
Echinococcus multilocularis	cyclin dependent kinase 1	0.0094	0.0697	0.0697
Brugia malayi	cell division control protein 2 homolog	0.0094	0.0697	0.0697
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0022	0.0056	0.0056
Loa Loa (eye worm)	fibroinase	0.1139	1	1
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Leishmania major	glucose transporter, lmgt1	0.0069	0.0478	0.0424
Brugia malayi	major facilitator superfamily protein	0.0031	0.0141	0.0141
Brugia malayi	latrophilin 2 splice variant baaae	0.0034	0.016	0.016
Echinococcus multilocularis	cyclin dependent kinase	0.0094	0.0697	0.0697
Brugia malayi	Sugar transporter family protein	0.0031	0.0141	0.0141
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0041	0.0231	0.0231
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0023	0.0023
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0041	0.0231	0.0231
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1139	1	1
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0212	0.1752	0.1752
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Echinococcus multilocularis	Sugar transporter ERD6 protein	0.0031	0.0141	0.0141
Loa Loa (eye worm)	hypothetical protein	0.1139	1	1
Echinococcus granulosus	roundabout 2	0.0018	0.0023	0.0023
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0018	0.0023	0.0023
Trypanosoma cruzi	cysteine protease, putative	0.0593	0.5137	0.5068
Echinococcus multilocularis	cathepsin b	0.0212	0.1752	0.1752
Echinococcus multilocularis	cathepsin L cysteine protease	0.1139	1	1
Trypanosoma cruzi	major cysteine proteinase, putative	0.0212	0.1752	0.1634
Loa Loa (eye worm)	hypothetical protein	0.0049	0.03	0.03
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Trichomonas vaginalis	sugar transporter, putative	0.0069	0.0478	0.0424
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0141	0.0085
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0139	0.0139
Toxoplasma gondii	cell-cycle-associated protein kinase CDK, putative	0.0094	0.0697	0.0644
Schistosoma mansoni	septate junction protein	0.0018	0.0023	0.0023
Echinococcus multilocularis	roundabout 2	0.0018	0.0023	0.0023
Brugia malayi	hypothetical protein	0.0031	0.0141	0.0141
Schistosoma mansoni	neuroglian	0.0018	0.0023	0.0023
Trichomonas vaginalis	conserved hypothetical protein	0.0069	0.0478	0.0424
Trypanosoma cruzi	hexose transporter, putative	0.0069	0.0478	0.0342
Giardia lamblia	Cathepsin B precursor	0.0212	0.1752	0.47
Plasmodium vivax	serine-repeat antigen 2 (SERA)	0.0212	0.1752	0.1732
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Plasmodium falciparum	calcium-dependent protein kinase 5	0.0022	0.0056	0.0033
Loa Loa (eye worm)	TK protein kinase	0.0038	0.0198	0.0198
Giardia lamblia	Hypothetical protein	0.0212	0.1752	0.47
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0212	0.1752	0.1752
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0018	0.0023	0.0023
Plasmodium vivax	calcium-dependent protein kinase 3, putative	0.0022	0.0056	0.0033
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0041	0.0231	0.0231
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0018	0.0023	0.0023
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0223	0.1848	0.1848
Brugia malayi	cathepsin B-like cysteine proteinase	0.0212	0.1752	0.1752
Echinococcus multilocularis	cysteine protease	0.1139	1	1
Echinococcus granulosus	cyclin dependent kinase 1	0.0094	0.0697	0.0697
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Trypanosoma brucei	glucose transporter, putative	0.0069	0.0478	0.0424
Trypanosoma cruzi	hexose transporter, putative	0.0069	0.0478	0.0342
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Leishmania major	cathepsin L-like protease	0.1139	1	1
Plasmodium falciparum	serine repeat antigen 9	0.0212	0.1752	0.1732
Onchocerca volvulus		0.0031	0.0141	0.0118
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0041	0.0231	0.0231
Plasmodium falciparum	major facilitator superfamily domain-containing protein, putative	0.0031	0.0141	0.0118
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0593	0.5137	0.5068
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.029	0.2441	0.6711
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0022	0.0056	0.0056
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Entamoeba histolytica	papain family cysteine protease domain containing protein	0.0212	0.1752	0.1705
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0759	0.6614	0.6595
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Mycobacterium ulcerans	hypothetical protein	0.0024	0.0079	0.4666
Entamoeba histolytica	cysteine protease, putative	0.0212	0.1752	0.1705
Echinococcus granulosus	synaptic vesicle 2 protein	0.0031	0.0141	0.0141
Brugia malayi	Prion-like-	0.0018	0.0023	0.0023
Entamoeba histolytica	cysteine proteinase, putative	0.0593	0.5137	0.511
Leishmania major	cathepsin L-like protease	0.1139	1	1
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0024
Brugia malayi	fibroinase precursor	0.0212	0.1752	0.1752
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0041	0.0231	0.0231
Echinococcus granulosus	General substrate transporter	0.0192	0.1569	0.1569
Plasmodium vivax	vivapain-1	0.0593	0.5137	0.5126
Echinococcus granulosus	cathepsin l cysteine peptidase	0.1139	1	1
Schistosoma mansoni	tyrosine kinase	0.0041	0.0231	0.0231
Schistosoma mansoni	cathepsin S (C01 family)	0.0212	0.1752	0.1752
Entamoeba histolytica	protein kinase, putative	0.0034	0.0163	0.0108
Brugia malayi	major facilitator superfamily protein	0.0031	0.0141	0.0141
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0507	0.4373	0.4373
Giardia lamblia	Cathepsin L precursor	0.0212	0.1752	0.47
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0023	0.0023
Trichomonas vaginalis	sugar transporter, putative	0.0069	0.0478	0.0424
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0212	0.1752	0.1705
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0041	0.0231	0.0231
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1139	1	1
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0024	0.0079	0.4666
Echinococcus granulosus	solute carrier family 22	0.0031	0.0141	0.0141
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0223	0.1848	0.1848
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0212	0.1752	0.1752
Trypanosoma brucei	glucose transporter, putative	0.0069	0.0478	0.0424
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Trypanosoma cruzi	major cysteine proteinase, putative	0.0212	0.1752	0.1634
Trichomonas vaginalis	Clan CA, family C1, cathepsin F-like cysteine peptidase	0.0212	0.1752	0.1705
Echinococcus multilocularis	cathepsin L	0.0212	0.1752	0.1752
Entamoeba histolytica	cysteine proteinase, putative	0.0593	0.5137	0.511
Echinococcus multilocularis	solute carrier family 2, facilitated glucose	0.0223	0.1848	0.1848
Toxoplasma gondii	cathepsin CPC2	0.029	0.2441	0.2398
Loa Loa (eye worm)	hypothetical protein	0.038	0.3248	0.3248
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0041	0.0231	0.0231
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0034	0.0163	0.0163
Echinococcus granulosus	contactin	0.0018	0.0023	0.0023
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Echinococcus multilocularis	peroxidasin	0.0018	0.0023	0.0023
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1139	1	1
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.029	0.2441	0.6711
Trichomonas vaginalis	CMGC family protein kinase	0.0094	0.0697	0.0644
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0212	0.1752	0.1705
Toxoplasma gondii	cathepsin CPL	0.1139	1	1
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0212	0.1752	0.1752
Echinococcus granulosus	cyclin dependent kinase 5	0.0094	0.0697	0.0697
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.1139	1	1
Giardia lamblia	Kinase, CMGC GSK	0.0104	0.0788	0.1887
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0212	0.1752	0.1752
Entamoeba histolytica	cysteine proteinase 2	0.0593	0.5137	0.511
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0141	0.0085
Trypanosoma cruzi	cysteine peptidase, putative	0.0593	0.5137	0.5068
Loa Loa (eye worm)	CAMK/CAMK2 protein kinase	0.0022	0.0056	0.0056
Echinococcus granulosus	protein kinase shaggy	0.0104	0.0788	0.0788
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0212	0.1752	0.1732
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0212	0.1752	0.1705
Schistosoma mansoni	nephrin	0.0039	0.021	0.021
Brugia malayi	Cathepsin L-like precursor	0.038	0.3248	0.3248
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0212	0.1752	0.1732
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0038	0.0198	0.0198
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0139	0.0139
Schistosoma mansoni	nephrin	0.0018	0.0023	0.0023
Schistosoma mansoni	glucose transporter	0.0031	0.0141	0.0141
Echinococcus granulosus	hemicentin 1	0.0018	0.0023	0.0023
Schistosoma mansoni	cathepsin C	0.0212	0.1752	0.1752
Echinococcus multilocularis	cysteine protease	0.1139	1	1
Mycobacterium ulcerans	sugar transporter	0.0031	0.0141	1
Toxoplasma gondii	cathepsin B	0.0212	0.1752	0.1705
Schistosoma mansoni	glucose transport protein	0.0223	0.1848	0.1848
Echinococcus granulosus	tyrosine protein kinase Blk	0.0038	0.0198	0.0198
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0034	0.0163	0.0163
Echinococcus multilocularis	cathepsin L	0.0593	0.5137	0.5137
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0593	0.5137	0.5126
Brugia malayi	protein-tyrosine kinase	0.0038	0.0198	0.0198
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0139	0.0139
Leishmania major	cell division protein kinase 2,cdc2-related kinase	0.0094	0.0697	0.0644
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0212	0.1752	0.1705
Leishmania major	4-coumarate:coa ligase-like protein	0.0024	0.0079	0.0022
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0024
Leishmania major	cathepsin L-like protease	0.1139	1	1
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Echinococcus granulosus	calcium dependent protein kinase	0.0017	0.001	0.001
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0141	0.0085
Echinococcus multilocularis	lachesin	0.0018	0.0023	0.0023
Echinococcus multilocularis	Immunoglobulin	0.0031	0.0139	0.0139
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0024
Leishmania major	4-coumarate:coa ligase-like protein	0.0024	0.0079	0.0022
Leishmania major	cathepsin L-like protease	0.1139	1	1
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0223	0.1848	0.1848
Echinococcus granulosus	tyrosine kinase	0.0038	0.0198	0.0198
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0298	0.0298
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0031	0.0139	0.0139
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0069	0.0478	0.0424
Echinococcus multilocularis	cathepsin b	0.0212	0.1752	0.1752
Echinococcus multilocularis	calcium dependent protein kinase	0.0017	0.001	0.001
Plasmodium falciparum	serine repeat antigen 2	0.0212	0.1752	0.1732
Schistosoma mansoni	serine/threonine protein kinase	0.0094	0.0697	0.0697
Plasmodium falciparum	serine repeat antigen 8	0.0212	0.1752	0.1732
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Brugia malayi	Peroxidasin	0.0018	0.0023	0.0023
Plasmodium vivax	calcium-dependent protein kinase, putative	0.0022	0.0056	0.0033
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0079	0.0079
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Loa Loa (eye worm)	sugar transporter	0.0223	0.1848	0.1848
Trichomonas vaginalis	glucose transporter, putative	0.0069	0.0478	0.0424
Loa Loa (eye worm)	hypothetical protein	0.038	0.3248	0.3248
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0031	0.0139	0.0139
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Onchocerca volvulus	Putative transporter	0.0031	0.0141	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.1139	1	1
Toxoplasma gondii	sugar transporter ST1	0.0031	0.0141	0.0085
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Loa Loa (eye worm)	sugar transporter	0.0031	0.0141	0.0141
Trypanosoma brucei	glucose transporter, putative	0.0069	0.0478	0.0424
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Echinococcus granulosus	cathepsin L cysteine proteinase	0.1139	1	1
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Schistosoma mansoni	glycogen synthase kinase 3-related (gsk3) (cmgc group III)	0.0104	0.0788	0.0788
Giardia lamblia	Cathepsin B precursor	0.0212	0.1752	0.47
Schistosoma mansoni	titin	0.0018	0.0023	0.0023
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0031	0.0139	0.0139
Leishmania major	glucose transporter, lmgt2	0.0069	0.0478	0.0424
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0047	0.0277	0.0277
Echinococcus granulosus	cathepsin l1	0.1139	1	1
Brugia malayi	Cathepsin L-like precursor	0.1139	1	1
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0023	0.0023
Echinococcus multilocularis	solute carrier family 22	0.0031	0.0141	0.0141
Echinococcus multilocularis	solute carrier family 22	0.0031	0.0141	0.0141
Trypanosoma cruzi	cysteine peptidase, putative	0.038	0.3248	0.3151
Echinococcus granulosus	roundabout 2	0.0018	0.0023	0.0023
Schistosoma mansoni	cathepsin B (C01 family)	0.0212	0.1752	0.1752
Giardia lamblia	Kinase, CMGC CDK	0.0094	0.0697	0.1622
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Schistosoma mansoni	cell adhesion molecule	0.0018	0.0023	0.0023
Giardia lamblia	Kinase, CMGC CDK	0.0094	0.0697	0.1622
Plasmodium vivax	vivapain-2	0.1139	1	1
Echinococcus multilocularis	tyrosine protein kinase otk	0.0018	0.0023	0.0023
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Echinococcus granulosus	glycogen synthase kinase 3 beta	0.0104	0.0788	0.0788
Trypanosoma brucei	glucose transporter, putative	0.0069	0.0478	0.0424
Brugia malayi	Cathepsin L-like precursor	0.1139	1	1
Echinococcus granulosus	tyrosine protein kinase HCK	0.0034	0.0163	0.0163
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0018	0.0023	0.0023
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0024
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0212	0.1752	0.1634
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0024	0.0079	0.4666
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0018	0.0023	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Echinococcus granulosus	defective proboscis extension response	0.0031	0.0139	0.0139
Onchocerca volvulus		0.0031	0.0141	0.0118
Brugia malayi	AMP-binding enzyme family protein	0.0024	0.0079	0.0079
Echinococcus multilocularis	roundabout 2	0.0018	0.0023	0.0023
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Trichomonas vaginalis	CMGC family protein kinase	0.0094	0.0697	0.0644
Trypanosoma cruzi	cysteine peptidase, putative	0.1139	1	1
Trypanosoma cruzi	cdc2-related kinase 3	0.0094	0.0697	0.0564
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0212	0.1752	0.1705
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Plasmodium vivax	vivapain-2	0.1139	1	1
Toxoplasma gondii	cell-cycle-associated protein kinase GSK, putative	0.0104	0.0788	0.0735
Mycobacterium ulcerans	sugar-transport integral membrane protein SugI	0.0031	0.0141	1
Echinococcus granulosus	peroxidasin	0.0018	0.0023	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0759	0.6614	0.6614
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0049	0.0298	0.0298
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0041	0.0229	0.0229
Trichomonas vaginalis	conserved hypothetical protein	0.0212	0.1752	0.1705
Plasmodium falciparum	dipeptidyl aminopeptidase 3	0.029	0.2441	0.2423
Mycobacterium ulcerans	fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT	0.0031	0.0141	1
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0023	0.0023
Schistosoma mansoni	tyrosine kinase	0.0022	0.0058	0.0058
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Entamoeba histolytica	cysteine protease, putative	0.0212	0.1752	0.1705
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0023	0.0023
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0069	0.0478	0.0424
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0018	0.0023	0.0023
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0031	0.0141	0.0141
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.038	0.3248	0.3248
Schistosoma mansoni	septate junction protein	0.0018	0.0023	0.0023
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0038	0.0198	0.0198
Onchocerca volvulus		0.0031	0.0141	0.0118
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0339	0.2879	0.2839
Trypanosoma cruzi	glycogen synthase kinase 3, putative	0.0104	0.0788	0.0656
Giardia lamblia	Cathepsin L precursor	0.0212	0.1752	0.47
Trypanosoma cruzi	cruzipain precursor, putative	0.038	0.3248	0.3151
Loa Loa (eye worm)	TK protein kinase	0.0034	0.0163	0.0163
Schistosoma mansoni	glucose transport protein	0.0223	0.1848	0.1848
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0223	0.1848	0.1848
Mycobacterium ulcerans	acyl-CoA synthetase	0.0024	0.0079	0.4666
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1139	1	1
Brugia malayi	hypothetical protein	0.0031	0.0141	0.0141
Loa Loa (eye worm)	cysteine protease	0.1139	1	1
Echinococcus granulosus	cathepsin b	0.0212	0.1752	0.1752
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0041	0.0231	0.0231
Trypanosoma brucei	cdc2-related kinase 3	0.0094	0.0697	0.0644
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Loa Loa (eye worm)	hypothetical protein	0.0759	0.6614	0.6614
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0022	0.0056	0.0056
Onchocerca volvulus	Tyrosine kinase homolog	0.0474	0.4076	0.4063
Toxoplasma gondii	sugar transporter ST2	0.0031	0.0141	0.0085
Loa Loa (eye worm)	hypothetical protein	0.0212	0.1752	0.1752
Echinococcus granulosus	solute carrier family 22	0.0031	0.0141	0.0141
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0018	0.0023	0.0023
Plasmodium vivax	protein kinase Crk2	0.0094	0.0697	0.0675
Echinococcus granulosus	lachesin	0.0018	0.0023	0.0023
Brugia malayi	Major Facilitator Superfamily protein	0.0031	0.0141	0.0141
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Plasmodium falciparum	serine repeat antigen 5	0.0212	0.1752	0.1732
Schistosoma mansoni	sugar transporter	0.0031	0.0141	0.0141
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Plasmodium falciparum	serine repeat antigen 6	0.0212	0.1752	0.1732
Trichomonas vaginalis	glucose transporter, putative	0.0031	0.0141	0.0085
Echinococcus granulosus	5'partial\|cyclin dependent kinase 1	0.0094	0.0697	0.0697
Onchocerca volvulus	Cathepsin L homolog	0.1139	1	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0018	0.0023	0.0023
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0018	0.0023	0.0023
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0022	0.0056	0.0056
Plasmodium falciparum	serine repeat antigen 1	0.0212	0.1752	0.1732
Onchocerca volvulus		0.0031	0.0141	0.0118
Trypanosoma cruzi	cruzipain precursor, putative	0.1139	1	1
Plasmodium vivax	dipeptidyl aminopeptidase 2, putative	0.0417	0.3568	0.3553
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.1139	1	1
Mycobacterium ulcerans	acyl-CoA synthetase	0.0024	0.0079	0.4666
Trichomonas vaginalis	Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase	0.0212	0.1752	0.1705
Trypanosoma brucei	glucose transporter 2A	0.0069	0.0478	0.0424
Loa Loa (eye worm)	hypothetical protein	0.0212	0.1752	0.1752
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0212	0.1752	0.1752
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0141	0.0085
Echinococcus multilocularis	contactin neuroglian septate junction protein	0.0018	0.0023	0.0023
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1139	1	1
Giardia lamblia	Cathepsin B precursor	0.0212	0.1752	0.47
Trypanosoma cruzi	cysteine proteinase, putative	0.0593	0.5137	0.5068
Echinococcus multilocularis	synaptic vesicle 2 protein	0.0031	0.0141	0.0141
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Leishmania major	cell division related protein kinase 2,cdc2-related kinase	0.0094	0.0697	0.0644
Loa Loa (eye worm)	hypothetical protein	0.0089	0.0651	0.0651
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0212	0.1752	0.1705
Brugia malayi	cathepsin L precursor	0.0212	0.1752	0.1752
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Brugia malayi	Cam kinase protein 1	0.0022	0.0056	0.0056
Onchocerca volvulus		0.0024	0.0079	0.0056
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0593	0.5137	0.5137
Echinococcus granulosus	cathepsin L	0.0593	0.5137	0.5137
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0041	0.0231	0.0231
Plasmodium vivax	serine-repeat antigen (SERA)	0.0212	0.1752	0.1732
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0212	0.1752	0.1752
Echinococcus multilocularis	neurotracting:lsamp:neurotrimin:obcam	0.0018	0.0023	0.0023
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type 1	0.0022	0.0056	0.0056
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0759	0.6614	0.6614
Giardia lamblia	Cathepsin B precursor	0.0212	0.1752	0.47
Trichomonas vaginalis	CMGC family protein kinase	0.0104	0.0788	0.0736
Echinococcus granulosus	Immunoglobulin	0.0031	0.0139	0.0139
Brugia malayi	Cathepsin L-like precursor	0.1139	1	1
Giardia lamblia	Cathepsin L precursor	0.0212	0.1752	0.47
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Loa Loa (eye worm)	hypothetical protein	0.0049	0.03	0.03
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0593	0.5137	0.5137
Giardia lamblia	Cysteine protease	0.0212	0.1752	0.47
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0417	0.3568	0.3568
Brugia malayi	Major Facilitator Superfamily protein	0.0031	0.0141	0.0141
Echinococcus multilocularis	neuroglian	0.0018	0.0023	0.0023
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0018	0.0023	0.0023
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0212	0.1752	0.1752
Brugia malayi	hypothetical protein	0.0031	0.0139	0.0139
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Entamoeba histolytica	cysteine protease, putative	0.0212	0.1752	0.1705
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Schistosoma mansoni	hypothetical protein	0.0223	0.1848	0.1848
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Echinococcus granulosus	tyrosine protein kinase otk	0.0018	0.0023	0.0023
Onchocerca volvulus		0.0212	0.1752	0.1733
Mycobacterium tuberculosis	Probable conserved integral membrane transport protein	0.0031	0.0141	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0593	0.5137	0.511
Trichomonas vaginalis	glucose transporter, putative	0.0069	0.0478	0.0424
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0212	0.1752	0.1705
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0212	0.1752	0.1752
Brugia malayi	Protein kinase domain containing protein	0.0094	0.0697	0.0697
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0031	0.0141	0.0141
Loa Loa (eye worm)	cathepsin B	0.0212	0.1752	0.1752
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1139	1	1
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Onchocerca volvulus		0.0759	0.6614	0.6607
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0038	0.0198	0.0198
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0212	0.1752	0.1752
Echinococcus granulosus	solute carrier family 22	0.0031	0.0141	0.0141
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0141	0.0085
Plasmodium vivax	calcium-dependent protein kinase 1, putative	0.0022	0.0056	0.0033
Entamoeba histolytica	cysteine protease, putative	0.1139	1	1
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Echinococcus granulosus	twitchin	0.0044	0.0256	0.0256
Plasmodium vivax	calcium-dependent protein kinase 4, putative	0.0022	0.0056	0.0033
Brugia malayi	intracellular kinase	0.0104	0.0788	0.0788
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0141	0.0141
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0018	0.0023	0.0023
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Wolbachia endosymbiont of Brugia malayi	major facilitator superfamily permease	0.0031	0.0141	0.5
Plasmodium vivax	serine-repeat antigen 4 (SERA)	0.0212	0.1752	0.1732
Entamoeba histolytica	protein kinase domain containing protein	0.0104	0.0788	0.0736
Trypanosoma brucei	glucose transporter 1E	0.0069	0.0478	0.0424
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.1139	1	1
Mycobacterium ulcerans	integral membrane transport protein	0.0031	0.0141	1
Giardia lamblia	Cathepsin L precursor	0.0212	0.1752	0.47
Plasmodium falciparum	serine repeat antigen 3	0.0212	0.1752	0.1732
Toxoplasma gondii	preprocathepsin c precursor, putative	0.0417	0.3568	0.3532
Entamoeba histolytica	cysteine protease, putative	0.0212	0.1752	0.1705
Entamoeba histolytica	protein kinase, putative	0.0104	0.0788	0.0736
Onchocerca volvulus	Cathepsin L homolog	0.0212	0.1752	0.1733
Toxoplasma gondii	cathepsin CPC1	0.0417	0.3568	0.3532
Plasmodium vivax	dipeptidyl aminopeptidase 1, putative	0.0417	0.3568	0.3553
Giardia lamblia	Kinase, CMGC GSK	0.0104	0.0788	0.1887
Schistosoma mansoni	protein kinase	0.0022	0.0056	0.0056
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0759	0.6614	0.6566
Plasmodium falciparum	glycogen synthase kinase 3	0.0104	0.0788	0.0766
Schistosoma mansoni	nuclear transcription factor X-box binding 1 (nfx1)	0.0031	0.0141	0.0141
Brugia malayi	Cathepsin L-like precursor	0.1139	1	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0212	0.1752	0.1752
Onchocerca volvulus		0.0031	0.0141	0.0118
Onchocerca volvulus		0.0031	0.0141	0.0118
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0223	0.1848	0.1848
Plasmodium vivax	serine-repeat antigen 4 (SERA), putative	0.0212	0.1752	0.1732
Brugia malayi	SRC-1	0.0041	0.0231	0.0231
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0593	0.5137	0.511
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or H-like cysteine peptidase	0.0212	0.1752	0.1705
Brugia malayi	Cathepsin L-like precursor	0.1139	1	1
Plasmodium falciparum	protein kinase 5	0.0094	0.0697	0.0675
Brugia malayi	Cathepsin L-like precursor	0.0759	0.6614	0.6614
Onchocerca volvulus		0.1139	1	1
Giardia lamblia	Cathepsin B-like cysteine proteinase 3 precursor	0.0212	0.1752	0.47
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0212	0.1752	0.1705
Brugia malayi	cathepsin F-like cysteine proteinase	0.0212	0.1752	0.1752
Giardia lamblia	Hypothetical protein	0.0212	0.1752	0.47
Plasmodium falciparum	calcium-dependent protein kinase 3	0.0022	0.0056	0.0033
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1139	1	1
Loa Loa (eye worm)	SRC-1	0.0041	0.0231	0.0231
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0018	0.0024	0.5
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0139	0.0139
Leishmania major	hypothetical protein, conserved	0.0031	0.0141	0.0085
Plasmodium vivax	sugar transporter, putative	0.0031	0.0141	0.0118
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1139	1	1
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0041	0.0231	0.0231
Brugia malayi	Fibronectin type III domain containing protein	0.0031	0.0139	0.0139
Entamoeba histolytica	cell division protein kinase 2, putative	0.0094	0.0697	0.0644
Echinococcus multilocularis	General substrate transporter	0.0192	0.1569	0.1569
Entamoeba histolytica	cysteine proteinase, putative	0.0759	0.6614	0.6595
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0024	0.0079	0.4666
Entamoeba histolytica	cysteine protease, putative	0.0593	0.5137	0.511
Giardia lamblia	Cysteine protease	0.0212	0.1752	0.47
Schistosoma mansoni	tyrosine kinase	0.0041	0.0231	0.0231
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0141	0.0085
Trypanosoma cruzi	cdc2-related kinase 3	0.0094	0.0697	0.0564

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 885137