Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | protein jagged 2 | 0.0017 | 0.0083 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.027 | 0.027 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Echinococcus granulosus | lamin | 0.0027 | 0.027 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0009 | 0.0009 |
Schistosoma mansoni | peroxidasin | 0.0547 | 1 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.027 | 0.0261 |
Brugia malayi | EGF-like domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Onchocerca volvulus | 0.0027 | 0.027 | 0.0188 | |
Brugia malayi | EGF-like domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.027 | 0.0261 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0017 | 0.0083 | 0.0074 |
Echinococcus multilocularis | musashi | 0.0027 | 0.027 | 0.0261 |
Brugia malayi | Muscle positioning protein 4 | 0.0017 | 0.0083 | 0.0048 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0017 | 0.0083 | 0.0074 |
Brugia malayi | Animal haem peroxidase family protein | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.027 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0017 | 0.0083 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Echinococcus granulosus | protein jagged 2 | 0.0017 | 0.0083 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0547 | 1 | 1 |
Echinococcus granulosus | peroxidasin | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0017 | 0.0083 | 0.0074 |
Echinococcus multilocularis | slit 2 protein | 0.0017 | 0.0083 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0547 | 1 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.027 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0017 | 0.0083 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0547 | 1 | 1 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0017 | 0.0083 | 0.0074 |
Schistosoma mansoni | lamin | 0.0027 | 0.027 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0017 | 0.0083 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.0017 | 0.0083 | 0.0074 |
Brugia malayi | EGF-like domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Onchocerca volvulus | 0.0027 | 0.027 | 0.0188 | |
Brugia malayi | Blistered cuticle protein 3 | 0.0547 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0017 | 0.0083 | 0.0074 |
Echinococcus multilocularis | protein jagged 1 | 0.0017 | 0.0083 | 0.0074 |
Loa Loa (eye worm) | notch protein | 0.0017 | 0.0083 | 0.0083 |
Onchocerca volvulus | Peroxidasin homolog | 0.0547 | 1 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.0547 | 1 | 1 |
Echinococcus multilocularis | lamin | 0.0027 | 0.027 | 0.0261 |
Brugia malayi | EGF-like domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Brugia malayi | Animal haem peroxidase family protein | 0.0547 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Echinococcus multilocularis | notch | 0.0017 | 0.0083 | 0.0074 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.027 | 0.0188 |
Schistosoma mansoni | lamin | 0.0027 | 0.027 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0261 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Onchocerca volvulus | Peroxidase homolog | 0.0547 | 1 | 1 |
Echinococcus granulosus | fibropellin Ia | 0.0017 | 0.0083 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Echinococcus multilocularis | neural cadherin | 0.0017 | 0.0083 | 0.0074 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.027 | 0.0235 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0547 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.027 | 0.0261 |
Echinococcus granulosus | notch | 0.0017 | 0.0083 | 0.0074 |
Echinococcus granulosus | slit 2 protein | 0.0017 | 0.0083 | 0.0074 |
Echinococcus granulosus | neural cadherin | 0.0017 | 0.0083 | 0.0074 |
Echinococcus multilocularis | protein jagged 2 | 0.0017 | 0.0083 | 0.0074 |
Echinococcus multilocularis | fibropellin Ia | 0.0017 | 0.0083 | 0.0074 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0017 | 0.0083 | 0.0074 |
Brugia malayi | EGF-like domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Brugia malayi | Animal haem peroxidase family protein | 0.0547 | 1 | 1 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0017 | 0.0083 | 0.0048 |
Brugia malayi | Delta serrate ligand family protein | 0.0017 | 0.0083 | 0.0048 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0017 | 0.0083 | 0.5 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Brugia malayi | Animal haem peroxidase family protein | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0547 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.027 | 0.027 |
Brugia malayi | Peroxidasin | 0.0547 | 1 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Echinococcus multilocularis | protein jagged 1 | 0.0017 | 0.0083 | 0.0074 |
Onchocerca volvulus | Peroxidase homolog | 0.0547 | 1 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Brugia malayi | EGF-like domain containing protein | 0.0017 | 0.0083 | 0.0048 |
Onchocerca volvulus | 0.0547 | 1 | 1 | |
Loa Loa (eye worm) | Notch2 | 0.0017 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Onchocerca volvulus | 0.0547 | 1 | 1 | |
Onchocerca volvulus | 0.0547 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0017 | 0.0083 | 0.0074 |
Brugia malayi | notch-like transmembrane receptor | 0.0017 | 0.0083 | 0.0048 |
Giardia lamblia | High cysteine protein | 0.0017 | 0.0083 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Echinococcus granulosus | protein jagged 1 | 0.0017 | 0.0083 | 0.0074 |
Echinococcus granulosus | delta-like protein 1 | 0.0017 | 0.0083 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Schistosoma mansoni | peroxidasin | 0.0547 | 1 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0547 | 1 | 1 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0017 | 0.0083 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0083 | 0.0083 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.