Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 0.5 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 1 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0082 | 0.0696 | 0.0271 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.0082 | 0.0696 | 0.5 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0082 | 0.0696 | 0.0271 |
Echinococcus granulosus | GPCR family 2 | 0.0265 | 0.295 | 0.9291 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.1925 | 0.1633 |
Echinococcus granulosus | alkaline phosphatase | 0.0196 | 0.2106 | 0.6275 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0265 | 0.295 | 0.9291 |
Schistosoma mansoni | tar DNA-binding protein | 0.0281 | 0.3149 | 0.4221 |
Echinococcus granulosus | alkaline phosphatase intestinal gene 2 | 0.0196 | 0.2106 | 0.6275 |
Schistosoma mansoni | hypothetical protein | 0.0572 | 0.6737 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0281 | 0.3149 | 0.4221 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0082 | 0.0696 | 0.0271 |
Schistosoma mansoni | hypothetical protein | 0.0265 | 0.295 | 0.3901 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0265 | 0.295 | 0.9291 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 1 |
Schistosoma mansoni | alkaline phosphatase | 0.0196 | 0.2106 | 0.2541 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 1 |
Brugia malayi | Isocitrate dehydrogenase | 0.0068 | 0.0528 | 0.0528 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0082 | 0.0696 | 1 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0054 | 0.0348 | 0.4996 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.0082 | 0.0696 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0281 | 0.3149 | 0.2902 |
Loa Loa (eye worm) | hypothetical protein | 0.0837 | 1 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0082 | 0.0696 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 1 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH2 | 0.0082 | 0.0696 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0265 | 0.295 | 0.9291 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0054 | 0.0348 | 0.4996 |
Echinococcus multilocularis | alkaline phosphatase, intestinal, gene 2 | 0.0196 | 0.2106 | 0.6275 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0281 | 0.3149 | 0.3149 |
Schistosoma mansoni | tar DNA-binding protein | 0.0281 | 0.3149 | 0.4221 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0837 | 1 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0281 | 0.3149 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0082 | 0.0696 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0068 | 0.0528 | 0.0642 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.0082 | 0.0696 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0572 | 0.6737 | 0.6737 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0068 | 0.0528 | 0.0642 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 1 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0082 | 0.0696 | 0.1242 |
Schistosoma mansoni | hypothetical protein | 0.0265 | 0.295 | 0.3901 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0265 | 0.295 | 0.295 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 1 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0082 | 0.0696 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0281 | 0.3149 | 0.2902 |
Schistosoma mansoni | hypothetical protein | 0.0265 | 0.295 | 0.3901 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0054 | 0.0348 | 0.4737 |
Brugia malayi | TAR-binding protein | 0.0281 | 0.3149 | 0.3149 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0265 | 0.295 | 0.295 |
Schistosoma mansoni | tar DNA-binding protein | 0.0281 | 0.3149 | 0.4221 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0068 | 0.0528 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.295 | 0.2696 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0082 | 0.0696 | 0.1242 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0068 | 0.0528 | 1 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.0082 | 0.0696 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.0944 | 0.067 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0068 | 0.0528 | 0.7585 |
Echinococcus granulosus | tar DNA binding protein | 0.0281 | 0.3149 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0068 | 0.0528 | 0.0642 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.0082 | 0.0696 | 0.5 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0068 | 0.0528 | 0.5174 |
Mycobacterium leprae | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0028 | 0.0036 | 0.5 |
Echinococcus multilocularis | intestinal type alkaline phosphatase 1 | 0.0196 | 0.2106 | 0.6275 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0054 | 0.0348 | 0.4737 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0265 | 0.295 | 0.2696 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0057 | 0.0384 | 0.0037 |
Schistosoma mansoni | hypothetical protein | 0.0265 | 0.295 | 0.3901 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0082 | 0.0696 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0837 | 1 | 1 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH1 | 0.0082 | 0.0696 | 1 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0057 | 0.0384 | 0.0037 |
Schistosoma mansoni | tar DNA-binding protein | 0.0281 | 0.3149 | 0.4221 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 0.5 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 1 |
Echinococcus multilocularis | intestinal type alkaline phosphatase | 0.0196 | 0.2106 | 0.6275 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0082 | 0.0696 | 0.1242 |
Echinococcus granulosus | intestinal type alkaline phosphatase 1 | 0.0196 | 0.2106 | 0.6275 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0028 | 0.0035 | 0.0035 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0082 | 0.0696 | 0.1242 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0068 | 0.0528 | 0.0642 |
Echinococcus granulosus | intestinal type alkaline phosphatase | 0.0196 | 0.2106 | 0.6275 |
Loa Loa (eye worm) | hypothetical protein | 0.0572 | 0.6737 | 0.6619 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0182 | 0.1925 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0281 | 0.3149 | 0.2902 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0068 | 0.0528 | 0.5174 |
Schistosoma mansoni | alkaline phosphatase | 0.0196 | 0.2106 | 0.2541 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0082 | 0.0696 | 0.0696 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0082 | 0.0696 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0068 | 0.0528 | 0.7585 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0068 | 0.0528 | 0.5174 |
Plasmodium falciparum | glyceraldehyde-3-phosphate dehydrogenase | 0.0082 | 0.0696 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0182 | 0.1925 | 0.1925 |
Brugia malayi | isocitrate dehydrogenase | 0.0068 | 0.0528 | 0.0528 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0068 | 0.0528 | 0.0186 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0082 | 0.0696 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0265 | 0.295 | 0.9291 |
Echinococcus multilocularis | alkaline phosphatase | 0.0196 | 0.2106 | 0.6275 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0082 | 0.0696 | 0.0271 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 1 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.0082 | 0.0696 | 1 |
Brugia malayi | RNA binding protein | 0.0281 | 0.3149 | 0.3149 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0068 | 0.0528 | 0.0642 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0265 | 0.295 | 0.9291 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0082 | 0.0696 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.