Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.0096 | 0.5759 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0746 | 0.1269 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0528 | 0.0888 | 0.1645 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0057 | 0.0066 | 0.0034 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0086 | 0.0115 | 1 |
Mycobacterium ulcerans | beta-ketoacyl synthase-like protein | 0.5742 | 1 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.014 | 0.021 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0062 | 0.0074 | 0.0138 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0086 | 0.0116 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0069 | 0.0086 | 0.0159 |
Echinococcus multilocularis | geminin | 0.0198 | 0.0312 | 0.0578 |
Loa Loa (eye worm) | TAR-binding protein | 0.0218 | 0.0346 | 0.0641 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.007 | 0.6054 |
Schistosoma mansoni | survival motor neuron protein | 0.0111 | 0.016 | 0.0296 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.0066 | 0.0122 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0086 | 0.0115 | 0.0214 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0022 | 0.0005 | 0.0009 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0069 | 0.0086 | 0.0159 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.006 | 0.007 | 0.6054 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.0111 | 0.0205 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.015 | 0.0278 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0092 | 0.0171 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0086 | 0.0115 | 0.0214 |
Brugia malayi | MAP kinase sur-1 | 0.006 | 0.007 | 0.013 |
Brugia malayi | intermediate filament protein | 0.0062 | 0.0074 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0092 | 0.0171 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0061 | 0.0072 | 0.004 |
Onchocerca volvulus | 0.0062 | 0.0074 | 0.3565 | |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0033 | 0.0023 | 0.0023 |
Echinococcus granulosus | tumor protein p63 | 0.0395 | 0.0656 | 0.1216 |
Loa Loa (eye worm) | acyl carrier protein | 0.0026 | 0.0012 | 0.0022 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0022 | 0.0005 | 0.0005 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0109 | 0.0156 | 0.0288 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0056 | 0.0063 | 0.0063 |
Schistosoma mansoni | lamin | 0.0062 | 0.0074 | 0.0138 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.006 | 0.007 | 0.013 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0005 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0016 | 0.003 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0135 | 0.0202 | 0.0375 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0086 | 0.0115 | 1 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0782 | 0.1333 | 0.2469 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0023 | 0.0006 | 0.0006 |
Schistosoma mansoni | tar DNA-binding protein | 0.0218 | 0.0346 | 0.0641 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0062 | 0.0074 | 0.0138 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0086 | 0.0115 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0135 | 0.0202 | 0.0375 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0086 | 0.0115 | 0.0214 |
Brugia malayi | hypothetical protein | 0.0083 | 0.0111 | 0.0205 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0061 | 0.0072 | 0.481 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0057 | 0.0066 | 0.0066 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0029 | 0.0053 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.167 | 0.2885 | 0.5344 |
Schistosoma mansoni | lamin | 0.0062 | 0.0074 | 0.0138 |
Onchocerca volvulus | 0.0111 | 0.016 | 0.7669 | |
Schistosoma mansoni | intermediate filament proteins | 0.0062 | 0.0074 | 0.0138 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0993 | 0.1702 | 0.3152 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0058 | 0.0067 | 0.0124 |
Schistosoma mansoni | high-affinity choline transporter | 0.0407 | 0.0676 | 0.1252 |
Echinococcus granulosus | tar DNA binding protein | 0.0218 | 0.0346 | 0.0641 |
Schistosoma mansoni | rab6-interacting | 0.0022 | 0.0005 | 0.0009 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0993 | 0.1702 | 0.3152 |
Schistosoma mansoni | loxhd1 | 0.0022 | 0.0005 | 0.0009 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.0096 | 0.5759 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.006 | 0.007 | 0.6054 |
Leishmania major | cathepsin L-like protease | 0.0075 | 0.0096 | 0.4575 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0067 | 0.0124 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0746 | 0.1269 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.006 | 0.007 | 0.6054 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0058 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 0.0676 | 0.1252 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0072 | 0.0092 | 0.0171 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0105 | 0.015 | 0.0278 |
Schistosoma mansoni | tar DNA-binding protein | 0.0218 | 0.0346 | 0.0641 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0111 | 0.016 | 0.0296 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0059 | 0.0068 | 0.591 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0069 | 0.0086 | 0.0159 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0061 | 0.0072 | 0.004 |
Echinococcus granulosus | solute carrier family 5 | 0.0045 | 0.0044 | 0.0082 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0068 | 0.0085 | 0.7347 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0022 | 0.0005 | 0.0009 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0528 | 0.0888 | 0.1645 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0105 | 0.015 | 0.0278 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0016 | 0.003 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0086 | 0.0115 | 1 |
Brugia malayi | Doublecortin family protein | 0.0022 | 0.0005 | 0.0009 |
Brugia malayi | Protein kinase domain containing protein | 0.0993 | 0.1702 | 0.3152 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0029 | 0.0053 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0047 | 0.0048 | 0.0047 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.007 | 0.6054 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0061 | 0.0072 | 0.0072 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0045 | 0.0044 | 0.0082 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0086 | 0.0116 | 0.0115 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0086 | 0.0116 | 0.0115 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0054 | 0.0059 | 0.0059 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0086 | 0.0115 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0218 | 0.0346 | 0.0641 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 0.0096 | 0.8326 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0046 | 0.0046 | 0.0014 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0083 | 0.0111 | 0.0205 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0045 | 0.0044 | 0.21 |
Schistosoma mansoni | tyrosine kinase | 0.0993 | 0.1702 | 0.3152 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0061 | 0.0072 | 0.481 |
Echinococcus multilocularis | musashi | 0.0062 | 0.0074 | 0.0138 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0061 | 0.0072 | 0.0072 |
Schistosoma mansoni | rab6-interacting | 0.0022 | 0.0005 | 0.0009 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.006 | 0.007 | 0.3327 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0061 | 0.0072 | 0.481 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0092 | 0.0171 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.006 | 0.007 | 0.013 |
Plasmodium falciparum | beta-ketoacyl-ACP synthase III | 0.5742 | 1 | 1 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.5742 | 1 | 1 |
Echinococcus granulosus | lamin | 0.0062 | 0.0074 | 0.0138 |
Onchocerca volvulus | 0.01 | 0.014 | 0.6723 | |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0086 | 0.0115 | 0.0214 |
Onchocerca volvulus | 0.0045 | 0.0044 | 0.2117 | |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0046 | 0.0046 | 0.172 |
Schistosoma mansoni | hypothetical protein | 0.0111 | 0.016 | 0.0296 |
Loa Loa (eye worm) | doublecortin family protein | 0.0022 | 0.0005 | 0.0009 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0218 | 0.0346 | 0.0641 |
Brugia malayi | AMP-binding enzyme family protein | 0.0054 | 0.0059 | 0.011 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.006 | 0.007 | 0.3327 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 0.0312 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0018 | 0.0034 |
Mycobacterium ulcerans | polyketide synthase | 0.0057 | 0.0066 | 0.0034 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0045 | 0.0044 | 0.0082 |
Brugia malayi | jmjC domain containing protein | 0.0069 | 0.0086 | 0.0159 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.0096 | 0.5759 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0993 | 0.1702 | 0.3152 |
Onchocerca volvulus | 0.0072 | 0.0092 | 0.4416 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.0096 | 0.5759 |
Onchocerca volvulus | 0.0058 | 0.0067 | 0.3206 | |
Schistosoma mansoni | jumonji domain containing protein | 0.0069 | 0.0086 | 0.0159 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 0.0312 | 0.0578 |
Brugia malayi | jmjC domain containing protein | 0.0069 | 0.0086 | 0.0159 |
Schistosoma mansoni | tar DNA-binding protein | 0.0218 | 0.0346 | 0.0641 |
Schistosoma mansoni | tyrosine kinase | 0.1653 | 0.2854 | 0.5287 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.014 | 0.021 | 1 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0407 | 0.0676 | 0.1252 |
Brugia malayi | Cell death protein 3 precursor | 0.0072 | 0.0092 | 0.0171 |
Loa Loa (eye worm) | intermediate filament protein | 0.0062 | 0.0074 | 0.0138 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.006 | 0.007 | 0.013 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0048 | 0.0049 | 0.2064 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.006 | 0.007 | 0.3327 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 0.0096 | 0.8326 |
Schistosoma mansoni | lipoxygenase | 0.0134 | 0.0199 | 0.0369 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.0096 | 0.5759 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0115 | 0.0214 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.0096 | 0.5759 |
Brugia malayi | GH02984p | 0.0407 | 0.0676 | 0.1252 |
Echinococcus multilocularis | RUN | 0.0022 | 0.0005 | 0.0009 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0048 | 0.0049 | 0.0049 |
Echinococcus multilocularis | tumor protein p63 | 0.0395 | 0.0656 | 0.1216 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0746 | 0.1269 | 1 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0045 | 0.0044 | 0.0082 |
Brugia malayi | Sodium:solute symporter family protein | 0.0045 | 0.0044 | 0.0082 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0045 | 0.0044 | 0.0082 |
Schistosoma mansoni | tar DNA-binding protein | 0.0218 | 0.0346 | 0.0641 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0782 | 0.1333 | 0.2469 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.0096 | 0.5759 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0086 | 0.0115 | 0.0214 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0086 | 0.0115 | 0.5495 |
Loa Loa (eye worm) | fatty acid synthase | 0.0057 | 0.0065 | 0.012 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.0096 | 0.5759 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.006 | 0.007 | 0.013 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0046 | 0.0046 | 0.0014 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.014 | 0.021 | 0.021 |
Echinococcus granulosus | epidermal growth factor receptor | 0.167 | 0.2885 | 0.5344 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0045 | 0.0044 | 0.0082 |
Echinococcus granulosus | caspase 2 | 0.0072 | 0.0092 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0044 | 0.0082 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.167 | 0.2885 | 0.5344 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0054 | 0.0059 | 0.011 |
Brugia malayi | MH2 domain containing protein | 0.0135 | 0.0202 | 0.0375 |
Schistosoma mansoni | lipoxygenase | 0.0093 | 0.0129 | 0.0239 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0134 | 0.0199 | 0.0369 |
Schistosoma mansoni | sodium/solute symporter | 0.0045 | 0.0044 | 0.0082 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.003 | 0.0018 | 0.0034 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0105 | 0.015 | 0.0278 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.015 | 0.0278 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0029 | 0.0016 | 0.0781 |
Leishmania major | cathepsin L-like protease | 0.0075 | 0.0096 | 0.4575 |
Brugia malayi | TAR-binding protein | 0.0218 | 0.0346 | 0.0641 |
Echinococcus multilocularis | solute carrier family 5 | 0.0045 | 0.0044 | 0.0082 |
Echinococcus multilocularis | caspase 2 | 0.0072 | 0.0092 | 0.0171 |
Echinococcus granulosus | epidermal growth factor receptor | 0.3109 | 0.5399 | 1 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0086 | 0.0115 | 0.0214 |
Onchocerca volvulus | 0.0022 | 0.0005 | 0.0232 | |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0062 | 0.0074 | 0.0138 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0075 | 0.0096 | 0.8326 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0746 | 0.1269 | 1 |
Schistosoma mansoni | inositol transporter | 0.0045 | 0.0044 | 0.0082 |
Mycobacterium ulcerans | polyketide synthase | 0.0061 | 0.0072 | 0.004 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0033 | 0.0024 | 0.0044 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0083 | 0.0111 | 0.0205 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0057 | 0.0066 | 0.4065 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.007 | 0.6054 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0041 | 0.0038 | 0.0038 |
Brugia malayi | follicle stimulating hormone receptor | 0.0518 | 0.0871 | 0.1613 |
Onchocerca volvulus | Huntingtin homolog | 0.0139 | 0.0208 | 1 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0057 | 0.0066 | 0.4065 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0111 | 0.0871 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0072 | 0.0092 | 0.0171 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0105 | 0.015 | 0.0278 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0111 | 0.0871 |
Schistosoma mansoni | inositol transporter | 0.0045 | 0.0044 | 0.0082 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0111 | 0.0871 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0022 | 0.0005 | 0.0009 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.0096 | 0.5759 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0058 | 0.0107 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0086 | 0.0115 | 1 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0746 | 0.1269 | 1 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0086 | 0.0116 | 0.0084 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.0096 | 0.5759 |
Onchocerca volvulus | 0.0022 | 0.0005 | 0.0232 | |
Echinococcus granulosus | lamin dm0 | 0.0062 | 0.0074 | 0.0138 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0111 | 0.0871 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0005 | 0.0009 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0782 | 0.1333 | 0.2469 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0022 | 0.0005 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0022 | 0.0041 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0086 | 0.0115 | 0.0214 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.006 | 0.007 | 0.6054 |
Echinococcus granulosus | neuropeptide s receptor | 0.0528 | 0.0888 | 0.1645 |
Onchocerca volvulus | 0.0062 | 0.0074 | 0.3565 | |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.5742 | 1 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0069 | 0.0086 | 0.0159 |
Echinococcus granulosus | RUN | 0.0022 | 0.0005 | 0.0009 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0072 | 0.0092 | 0.4416 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0105 | 0.015 | 0.0278 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0041 | 0.0037 | 0.1765 |
Onchocerca volvulus | Huntingtin homolog | 0.0139 | 0.0208 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0218 | 0.0346 | 0.0641 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0528 | 0.0888 | 0.1645 |
Echinococcus granulosus | sodium:glucose cotransporter | 0.0045 | 0.0044 | 0.0082 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.015 | 0.0278 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.014 | 0.021 | 0.0179 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0022 | 0.0005 | 0.0009 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0069 | 0.0086 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0005 | 0.0009 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.014 | 0.021 | 0.0389 |
Schistosoma mansoni | tyrosine kinase | 0.1653 | 0.2854 | 0.5287 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0545 | 0.0918 | 0.17 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0045 | 0.0044 | 0.0082 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0056 | 0.0063 | 0.0063 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0057 | 0.0066 | 0.0034 |
Leishmania major | cathepsin L-like protease | 0.0075 | 0.0096 | 0.4575 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0058 | 0.0107 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0103 | 0.0146 | 0.7021 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.014 | 0.021 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0072 | 0.0134 |
Schistosoma mansoni | tyrosine kinase | 0.0993 | 0.1702 | 0.3152 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0092 | 0.0171 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0083 | 0.0111 | 0.0205 |
Echinococcus multilocularis | 0.0962 | 0.1647 | 0.3051 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0218 | 0.0346 | 0.0641 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.007 | 0.6054 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0074 | 0.0138 |
Echinococcus granulosus | intermediate filament protein | 0.0062 | 0.0074 | 0.0138 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.3109 | 0.5399 | 1 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) | 0.5742 | 1 | 1 |
Onchocerca volvulus | 0.0054 | 0.0059 | 0.2849 | |
Schistosoma mansoni | tyrosine kinase | 0.1653 | 0.2854 | 0.5287 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0069 | 0.0086 | 0.0159 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0086 | 0.0115 | 1 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0057 | 0.0066 | 0.0034 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.014 | 0.021 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0134 | 0.0248 |
Mycobacterium ulcerans | thioesterase | 0.0048 | 0.0049 | 0.0017 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0005 | 0.0009 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 0.0096 | 0.8326 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0069 | 0.0086 | 0.0159 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.3109 | 0.5399 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.014 | 0.021 | 0.0389 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0058 | 0.0107 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0105 | 0.015 | 0.0278 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.014 | 0.021 | 0.0389 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0134 | 0.0199 | 0.0369 |
Mycobacterium ulcerans | thioesterase TesA | 0.0048 | 0.0049 | 0.0017 |
Brugia malayi | hypothetical protein | 0.0545 | 0.0918 | 0.17 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0057 | 0.0066 | 0.0066 |
Schistosoma mansoni | polycystin 1-related | 0.0022 | 0.0005 | 0.0009 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0022 | 0.0005 | 0.0009 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0029 | 0.0053 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0218 | 0.0346 | 0.0641 |
Echinococcus multilocularis | lamin | 0.0062 | 0.0074 | 0.0138 |
Echinococcus granulosus | geminin | 0.0198 | 0.0312 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0208 | 0.0386 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0518 | 0.0871 | 0.1613 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0057 | 0.0066 | 0.0034 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0086 | 0.0115 | 0.0214 |
Echinococcus granulosus | insulin receptor | 0.0993 | 0.1702 | 0.3152 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0005 | 0.0009 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0033 | 0.0024 | 0.0044 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0061 | 0.0072 | 0.3435 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0022 | 0.0005 | 0.0005 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.2787 | 0.4836 | 0.8958 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0061 | 0.0072 | 0.0072 |
Schistosoma mansoni | serine/threonine protein kinase | 0.006 | 0.007 | 0.013 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0057 | 0.0066 | 0.0066 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0072 | 0.0092 | 0.0171 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0545 | 0.0918 | 0.17 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.0096 | 0.5759 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.014 | 0.021 | 0.0179 |
Echinococcus granulosus | mitogen activated protein kinase | 0.006 | 0.007 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0545 | 0.0918 | 0.17 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0407 | 0.0676 | 0.1252 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0086 | 0.0115 | 0.091 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.5742 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0208 | 0.0386 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0057 | 0.0066 | 0.0122 |
Echinococcus multilocularis | insulin receptor | 0.0993 | 0.1702 | 0.3152 |
Brugia malayi | hypothetical protein | 0.0139 | 0.0208 | 0.0386 |
Plasmodium vivax | beta-ketoacyl-acyl carrier protein synthase III precursor, putative | 0.5742 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.3109 | 0.5399 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.167 | 0.2885 | 0.5344 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0037 | 0.0031 | 0.1465 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.003 | 0.0018 | 0.0034 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.3109 | 0.5399 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.167 | 0.2885 | 0.5344 |
Brugia malayi | RNA binding protein | 0.0218 | 0.0346 | 0.0641 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0086 | 0.0115 | 0.0214 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.