Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cathepsin b | 0.0726 | 0.7971 | 0.7971 |
Brugia malayi | Cathepsin L-like precursor | 0.0804 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0804 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0804 | 1 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0804 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0804 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0804 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0726 | 0.7971 | 0.7971 |
Echinococcus granulosus | cathepsin l1 | 0.0544 | 0.3182 | 0.3182 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0726 | 0.7971 | 0.7971 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0804 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0544 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0804 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0804 | 1 | 1 |
Onchocerca volvulus | 0.0804 | 1 | 1 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0804 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0804 | 1 | 0.5 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0726 | 0.7971 | 0.7971 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0804 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0804 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0804 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0804 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0804 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0804 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0804 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0804 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0804 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0726 | 0.7971 | 0.7971 |
Onchocerca volvulus | 0.0804 | 1 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0804 | 1 | 1 |
Onchocerca volvulus | 0.0804 | 1 | 1 | |
Brugia malayi | cathepsin L-like precursor | 0.0544 | 0.3182 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0804 | 1 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0804 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0544 | 0.3182 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0804 | 1 | 1 |
Onchocerca volvulus | 0.0804 | 1 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0726 | 0.7971 | 0.7971 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0544 | 0.3182 | 0.3182 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0804 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0804 | 1 | 0.5 |
Loa Loa (eye worm) | cysteine protease | 0.0804 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0804 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0804 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0726 | 0.7971 | 0.7971 |
Brugia malayi | Cathepsin L-like precursor | 0.0804 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0804 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0804 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0804 | 1 | 1 |
Onchocerca volvulus | 0.0804 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0804 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0726 | 0.7971 | 0.7971 |
Leishmania major | cathepsin L-like protease | 0.0804 | 1 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.0726 | 0.7971 | 0.7971 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0804 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0804 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0804 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0804 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0804 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Onchocerca volvulus | 0.0804 | 1 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0804 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0544 | 0.3182 | 0.3182 |
Entamoeba histolytica | cysteine protease, putative | 0.0804 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0544 | 0.3182 | 0.3182 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0804 | 1 | 1 |
Onchocerca volvulus | 0.0804 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0544 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0544 | 0.3182 | 0.3182 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0804 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0804 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0804 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0726 | 0.7971 | 0.7971 |
Toxoplasma gondii | cathepsin CPL | 0.0804 | 1 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0804 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0726 | 0.7971 | 0.7025 |
Brugia malayi | Cathepsin L-like precursor | 0.0544 | 0.3182 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.0804 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0804 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0804 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0804 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0804 | 1 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0804 | 1 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0804 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.