Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1135 | 0.2624 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1135 | 0.2624 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0045 | 0.0601 | 0.6177 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.1508 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0694 | 0.0614 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.0601 | 0.3419 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.1508 | 0.1697 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.1135 | 0.1278 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0046 | 0.0638 | 0.1184 |
Echinococcus multilocularis | lamin | 0.0052 | 0.0833 | 0.0937 |
Onchocerca volvulus | 0.0052 | 0.0833 | 1 | |
Loa Loa (eye worm) | intermediate filament protein | 0.0052 | 0.0833 | 0.0833 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.1135 | 0.1135 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0349 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0504 | 0.0504 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0028 | 0.0085 | 0.0085 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.1135 | 0.1059 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0694 | 0.0694 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0049 | 0.0728 | 0.5 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.1508 | 0.1697 |
Schistosoma mansoni | lamin | 0.0052 | 0.0833 | 0.1749 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0504 | 0.4571 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0229 | 0.0144 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0074 | 0.1508 | 0.1508 |
Echinococcus multilocularis | lamin dm0 | 0.0052 | 0.0833 | 0.0937 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0504 | 0.2714 |
Leishmania major | hypothetical protein, conserved | 0.0049 | 0.0728 | 0.5 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0134 | 0.3353 | 0.3772 |
Schistosoma mansoni | thyroid hormone receptor | 0.0144 | 0.3684 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0144 | 0.3684 | 0.4145 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0134 | 0.3353 | 0.3772 |
Echinococcus multilocularis | tumor protein p63 | 0.0313 | 0.8887 | 1 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.1508 | 0.3704 |
Brugia malayi | intermediate filament protein | 0.0052 | 0.0833 | 0.0754 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1135 | 0.2624 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0803 | 0.0803 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0052 | 0.0833 | 0.0833 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0504 | 0.2714 |
Schistosoma mansoni | intermediate filament proteins | 0.0052 | 0.0833 | 0.1749 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.1135 | 0.1135 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.0601 | 0.3419 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.1135 | 0.1135 |
Echinococcus granulosus | lamin dm0 | 0.0052 | 0.0833 | 0.0937 |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.0504 | 0.0422 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.1508 | 0.1697 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0049 | 0.0728 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0227 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0728 | 0.0728 |
Echinococcus multilocularis | musashi | 0.0052 | 0.0833 | 0.0937 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0049 | 0.0728 | 0.5 |
Brugia malayi | RNA binding protein | 0.0062 | 0.1135 | 0.1059 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0049 | 0.0728 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0052 | 0.0833 | 0.0937 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1135 | 0.2624 |
Brugia malayi | Heterochromatin protein 1 | 0.0074 | 0.1508 | 0.1435 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0694 | 0.0614 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0229 | 0.0229 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.1135 | 0.1278 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.1508 | 0.3704 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.1508 | 0.1697 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.1508 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0638 | 0.0638 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0194 | 0.011 |
Onchocerca volvulus | 0.0052 | 0.0833 | 1 | |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0049 | 0.0728 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1135 | 0.2624 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0052 | 0.0833 | 0.0754 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.1135 | 0.1059 |
Echinococcus granulosus | tumor protein p63 | 0.0313 | 0.8887 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0134 | 0.3353 | 0.9041 |
Schistosoma mansoni | lamin | 0.0052 | 0.0833 | 0.1749 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0728 | 0.0648 |
Schistosoma mansoni | thyroid hormone receptor | 0.0144 | 0.3684 | 1 |
Onchocerca volvulus | 0.0046 | 0.0638 | 0.6776 | |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0049 | 0.0728 | 0.5 |
Echinococcus granulosus | lamin | 0.0052 | 0.0833 | 0.0937 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0694 | 0.0694 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0349 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0049 | 0.0728 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0833 | 0.0833 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.