Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | carboxylesterase 5A | 0.0537 | 1 | 1 |
Plasmodium falciparum | hexose transporter | 0.0122 | 0.169 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0537 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0091 | 0.1058 | 0.6265 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0038 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0038 | 0 | 0.5 |
Onchocerca volvulus | 0.0091 | 0.1058 | 0.5 | |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0122 | 0.169 | 0.0706 |
Echinococcus granulosus | acetylcholinesterase | 0.0537 | 1 | 1 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0122 | 0.169 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0122 | 0.169 | 0.0706 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0091 | 0.1058 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0038 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0537 | 1 | 1 |
Leishmania major | glucose transporter, lmgt2 | 0.0038 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0038 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter 2A | 0.0038 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0537 | 1 | 1 |
Trypanosoma brucei | glucose transporter 1E | 0.0038 | 0 | 0.5 |
Onchocerca volvulus | 0.0091 | 0.1058 | 0.5 | |
Trypanosoma brucei | glucose transporter, putative | 0.0038 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0122 | 0.169 | 0.0706 |
Trypanosoma brucei | glucose transporter, putative | 0.0038 | 0 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0091 | 0.1058 | 0.6265 |
Echinococcus multilocularis | General substrate transporter | 0.0105 | 0.1345 | 0.0321 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0122 | 0.169 | 0.0706 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0091 | 0.1058 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0122 | 0.169 | 0.0706 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0038 | 0 | 0.5 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0038 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0122 | 0.169 | 0.0706 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0091 | 0.1058 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0038 | 0 | 0.5 |
Plasmodium vivax | hexose transporter | 0.0122 | 0.169 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0091 | 0.1058 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0038 | 0 | 0.5 |
Leishmania major | glucose transporter, lmgt3 | 0.0038 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0122 | 0.169 | 1 |
Trypanosoma cruzi | hexose transporter, putative | 0.0038 | 0 | 0.5 |
Brugia malayi | Sugar transporter family protein | 0.0122 | 0.169 | 0.0706 |
Trypanosoma brucei | glucose transporter, putative | 0.0038 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0537 | 1 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0038 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0038 | 0 | 0.5 |
Echinococcus granulosus | General substrate transporter | 0.0105 | 0.1345 | 0.0321 |
Loa Loa (eye worm) | hypothetical protein | 0.0537 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0537 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0537 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0537 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0537 | 1 | 1 |
Leishmania major | glucose transporter, lmgt1 | 0.0038 | 0 | 0.5 |
Loa Loa (eye worm) | sugar transporter | 0.0122 | 0.169 | 0.0706 |
Onchocerca volvulus | 0.0091 | 0.1058 | 0.5 | |
Schistosoma mansoni | glucose transport protein | 0.0122 | 0.169 | 0.0706 |
Schistosoma mansoni | glucose transport protein | 0.0122 | 0.169 | 0.0706 |
Brugia malayi | Carboxylesterase family protein | 0.0537 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0122 | 0.169 | 0.0706 |
Onchocerca volvulus | 0.0091 | 0.1058 | 0.5 | |
Trypanosoma brucei | glucose transporter, putative | 0.0038 | 0 | 0.5 |
Onchocerca volvulus | 0.0091 | 0.1058 | 0.5 | |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0122 | 0.169 | 0.0706 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0122 | 0.169 | 0.0706 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0122 | 0.169 | 0.0706 |
Trypanosoma cruzi | hexose transporter | 0.0038 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.