Detailed information for compound 887015

Basic information

Technical information
  • TDR Targets ID: 887015
  • Name: ethyl 3-[(2,4-difluorophenyl)sulfonyl-(phenyl methyl)amino]propanoate
  • MW: 383.41 | Formula: C18H19F2NO4S
  • H donors: 0 H acceptors: 3 LogP: 2.96 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)CCN(S(=O)(=O)c1ccc(cc1F)F)Cc1ccccc1
  • InChi: 1S/C18H19F2NO4S/c1-2-25-18(22)10-11-21(13-14-6-4-3-5-7-14)26(23,24)17-9-8-15(19)12-16(17)20/h3-9,12H,2,10-11,13H2,1H3
  • InChiKey: WAAMROXJXNKULU-UHFFFAOYSA-N  

Network

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Synonyms

  • 3-[(2,4-difluorophenyl)sulfonyl-(phenylmethyl)amino]propanoic acid ethyl ester
  • 3-[benzyl-(2,4-difluorophenyl)sulfonyl-amino]propionic acid ethyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Trichomonas vaginalis tubulin alpha chain, putative 0.0048 0.0033 0.0058
Loa Loa (eye worm) WD40 repeat protein 0.0071 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus granulosus Tubulin beta 2C chain 0.0048 0.0033 0.0033
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Toxoplasma gondii SPRY domain-containing protein 0.004 0.0019 0.0423
Trypanosoma cruzi hypothetical protein, conserved 0.0061 0.0058 0.1395
Toxoplasma gondii subtilisin SUB2 0.0247 0.0413 0.9293
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0015 0.002
Echinococcus granulosus membrane bound transcription factor site 1 0.0247 0.0413 0.0413
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1468 0.2735 0.4814
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Onchocerca volvulus 0.0038 0.0015 0.0375
Schistosoma mansoni site-1 peptidase (S08 family) 0.0247 0.0413 0.0413
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.3016 0.568 1
Onchocerca volvulus 0.0038 0.0015 0.0375
Echinococcus multilocularis somatostatin receptor 0.0038 0.0015 0.002
Schistosoma mansoni retinoblastoma binding protein 0.0075 0.0086 0.0086
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Echinococcus multilocularis tissue type plasminogen activator 0.0061 0.0058 0.0073
Brugia malayi G protein-coupled receptor 0.0038 0.0015 0.0015
Plasmodium falciparum subtilisin-like protease 2 0.0247 0.0413 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0048 0.0033 0.0042
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0038 0.0015 0.002
Mycobacterium leprae Possible secreted protease 0.0247 0.0413 1
Onchocerca volvulus 0.0038 0.0015 0.0375
Loa Loa (eye worm) beta-tubulin 0.0048 0.0033 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0015 0.002
Trichomonas vaginalis conserved hypothetical protein 0.112 0.2073 0.365
Toxoplasma gondii subtilisin SUB7 0.0247 0.0413 0.9293
Brugia malayi hypothetical protein 0.0103 0.0138 0.0138
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0247 0.0413 0.0525
Toxoplasma gondii subtilisin SUB1 0.0247 0.0413 0.9293
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0015 0.0015
Toxoplasma gondii kringle domain-containing protein 0.0061 0.0058 0.1296
Schistosoma mansoni opsin-like receptor 0.0038 0.0015 0.0015
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0015 0.0015
Plasmodium falciparum cysteine repeat modular protein 1 0.0061 0.0058 0.0831
Echinococcus multilocularis neuropeptide receptor A26 0.0038 0.0015 0.002
Brugia malayi follicle stimulating hormone receptor 0.0038 0.0015 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0015 0.002
Echinococcus granulosus peptide allatostatin:somatostatin 0.0038 0.0015 0.0015
Trichomonas vaginalis WD repeat domain, putative 0.0071 0.0077 0.0135
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0015 0.0015
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0247 0.0413 0.0413
Brugia malayi Dopamine receptor protein 1 0.0038 0.0015 0.0015
Brugia malayi neuroendocrine convertase 1 precursor 0.4198 0.7928 0.7928
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0025 0.0045
Schistosoma mansoni amine GPCR 0.0038 0.0015 0.0015
Brugia malayi hypothetical protein 0.0038 0.0015 0.0015
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Schistosoma mansoni neuropeptide receptor 0.0038 0.0015 0.0015
Onchocerca volvulus Huntingtin homolog 0.0103 0.0138 0.3341
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.3016 0.568 1
Echinococcus granulosus allatostatin A receptor 0.0038 0.0015 0.0015
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0015 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0015 0.0015
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0247 0.0413 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1468 0.2735 0.4814
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0247 0.0413 0.0413
Onchocerca volvulus Neuropeptide F receptor homolog 0.0038 0.0015 0.0375
Brugia malayi Protein kinase domain containing protein 0.0061 0.0058 0.0058
Echinococcus multilocularis Furin 1 0.1468 0.2735 0.3475
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0015 0.0015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Schistosoma mansoni opsin-like receptor 0.0038 0.0015 0.0015
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0247 0.0413 0.0413
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0015 0.002
Brugia malayi GnHR receptor homolog 0.0038 0.0015 0.0015
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0015 0.0015
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0038 0.0015 0.002
Onchocerca volvulus 0.0038 0.0015 0.0375
Brugia malayi celfurPC protein 0.4167 0.787 0.787
Schistosoma mansoni tubulin subunit beta 0.0048 0.0033 0.0033
Loa Loa (eye worm) endoprotease bli-4 0.5287 1 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Onchocerca volvulus 0.0199 0.0321 0.7757
Toxoplasma gondii subtilisin SUB6 0.0247 0.0413 0.9293
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0015 0.002
Echinococcus multilocularis orexin receptor type 2 0.0038 0.0015 0.002
Schistosoma mansoni amine GPCR 0.0038 0.0015 0.0015
Brugia malayi AKH receptor 0.0038 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.112 0.2073 0.365
Schistosoma mansoni histamine h1 receptor 0.0038 0.0015 0.0015
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Brugia malayi hypothetical protein 0.0038 0.0015 0.0015
Echinococcus granulosus set1:ash2 histone methyltransferase complex 0.0044 0.0025 0.0025
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.122 0.2264 0.3986
Echinococcus multilocularis epidermal growth factor receptor 0.0458 0.0813 0.1034
Schistosoma mansoni neuropeptide f receptor 76f 0.0038 0.0015 0.0015
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0015 0.0015
Brugia malayi hypothetical protein 0.0038 0.0015 0.0015
Plasmodium vivax subtilisin-like serine protease, putative 0.0247 0.0413 1
Brugia malayi Tubulin beta-1 chain 0.0048 0.0033 0.0033
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0038 0.0015 0.0015
Brugia malayi Will die slowly protein 0.0071 0.0077 0.0077
Trichomonas vaginalis tubulin epsilon chain, putative 0.0048 0.0033 0.0058
Echinococcus granulosus 7TM GPCR rhodopsin 0.0038 0.0015 0.0015
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0038 0.0015 0.002
Schistosoma mansoni tubulin subunit beta 0.0048 0.0033 0.0033
Onchocerca volvulus 0.0101 0.0134 0.3236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0015 0.0015
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0015 0.0015
Brugia malayi beta-tubulin, identical 0.0048 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.2371 0.4453 0.4453
Trichomonas vaginalis retinoblastoma binding protein, putative 0.0075 0.0086 0.0151
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0015 0.0015
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0038 0.0015 0.0015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1468 0.2735 0.4814
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0038 0.0015 0.0015
Onchocerca volvulus 0.0038 0.0015 0.0375
Loa Loa (eye worm) hypothetical protein 0.0559 0.1007 0.1007
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0025 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0015 0.0015
Schistosoma mansoni furin-1 (S08 family) 0.2518 0.4733 0.4733
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0015 0.0015
Loa Loa (eye worm) SPRY domain-containing protein 0.004 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0247 0.0413 1
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.1468 0.2735 0.2735
Onchocerca volvulus 0.0038 0.0015 0.0375
Schistosoma mansoni amine GPCR 0.0038 0.0015 0.0015
Echinococcus multilocularis sex peptide receptor 0.0038 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0247 0.0413 1
Onchocerca volvulus 0.0247 0.0413 1
Schistosoma mansoni biogenic amine receptor 0.0038 0.0015 0.0015
Echinococcus granulosus epidermal growth factor receptor 0.0458 0.0813 0.0813
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.5287 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0247 0.0413 0.0728
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0038 0.0015 0.0015
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0038 0.0015 0.0015
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0015 0.002
Brugia malayi SPRY domain containing protein 0.0044 0.0025 0.0025
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0015 0.002
Echinococcus multilocularis Mastin 0.0054 0.0045 0.0058
Echinococcus multilocularis Tubulin beta 2C chain 0.0048 0.0033 0.0042
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.3016 0.568 0.568
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0038 0.0015 0.0015
Echinococcus multilocularis allatostatin A receptor 0.0038 0.0015 0.002
Brugia malayi hypothetical protein 0.0038 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.112 0.2073 0.365
Brugia malayi G-protein coupled receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.112 0.2073 0.365
Toxoplasma gondii beta tubulin 0.0048 0.0033 0.0742
Echinococcus granulosus g protein coupled receptor 0.0038 0.0015 0.0015
Echinococcus granulosus neuropeptide s receptor 0.0038 0.0015 0.0015
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0247 0.0413 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Trichomonas vaginalis conserved hypothetical protein 0.0247 0.0413 0.0728
Trichomonas vaginalis conserved hypothetical protein 0.0247 0.0413 0.0728
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0247 0.0413 1
Schistosoma mansoni amine GPCR 0.0038 0.0015 0.0015
Echinococcus granulosus fmrfamide receptor 0.0038 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0038 0.0015 0.0015
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0015 0.0015
Schistosoma mansoni tubulin subunit beta 0.0048 0.0033 0.0033
Echinococcus granulosus g protein coupled receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) BEN-1 protein 0.0048 0.0033 0.0033
Echinococcus granulosus serotonin receptor 0.0038 0.0015 0.0015
Onchocerca volvulus 0.0038 0.0015 0.0375
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0015 0.002
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0038 0.0015 0.002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0015 0.0015
Schistosoma mansoni neuropeptide receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus granulosus tubulin subunit beta 0.0048 0.0033 0.0033
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) tubulin beta-1 chain 0.0048 0.0033 0.0033
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0038 0.0015 0.0015
Trichomonas vaginalis set domain proteins, putative 0.0199 0.0321 0.0564
Echinococcus granulosus tubulin beta 1 chain 0.0048 0.0033 0.0033
Giardia lamblia Furin precursor putative serine protease 0.122 0.2264 0.7324
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0015 0.002
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0015 0.0015
Echinococcus granulosus neuroendocrine convertase 2 0.3739 0.7055 0.7055
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0048 0.0033 0.0042
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0015 0.002
Brugia malayi Furin-like cysteine rich region family protein 0.0458 0.0813 0.0813
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0038 0.0015 0.0015
Echinococcus granulosus furin 0.5287 1 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus multilocularis membrane bound transcription factor site 1 0.0247 0.0413 0.0525
Echinococcus granulosus Tubulin beta 2C chain 0.0048 0.0033 0.0033
Brugia malayi hypothetical protein 0.0038 0.0015 0.0015
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.01 0.0133 0.0235
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0015 0.0015
Toxoplasma gondii beta-tubulin, putative 0.0048 0.0033 0.0742
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Plasmodium falciparum subtilisin-like protease 3 0.0247 0.0413 1
Onchocerca volvulus 0.0038 0.0015 0.0375
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Echinococcus granulosus somatostatin receptor 0.0038 0.0015 0.0015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1468 0.2735 0.4814
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Loa Loa (eye worm) TK/ROR protein kinase 0.0061 0.0058 0.0058
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) subtilase 0.0247 0.0413 0.0413
Brugia malayi proprotein convertase 2 0.3739 0.7055 0.7055
Giardia lamblia High cysteine membrane protein Group 2 0.1649 0.3079 1
Plasmodium vivax subtilisin-like protease 1 0.0247 0.0413 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Trichomonas vaginalis conserved hypothetical protein 0.112 0.2073 0.365
Loa Loa (eye worm) hypothetical protein 0.0106 0.0144 0.0144
Schistosoma mansoni growth hormone secretagogue receptor 0.0038 0.0015 0.0015
Echinococcus multilocularis G-protein coupled receptor, putative 0.0038 0.0015 0.002
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Echinococcus granulosus beta tubulin 0.0048 0.0033 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.112 0.2073 0.365
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0038 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus granulosus Tubulin beta 2C chain 0.0048 0.0033 0.0033
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0054 0.0045 0.0045
Echinococcus granulosus tissue type plasminogen activator 0.0061 0.0058 0.0058
Trypanosoma brucei beta tubulin 0.0048 0.0033 0.0799
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0075 0.0086 0.0086
Toxoplasma gondii subtilisin SUB5 0.0247 0.0413 0.9293
Schistosoma mansoni tubulin subunit beta 0.0048 0.0033 0.0033
Trypanosoma cruzi beta tubulin, putative 0.0048 0.0033 0.0799
Trichomonas vaginalis conserved hypothetical protein 0.112 0.2073 0.365
Schistosoma mansoni site-1 peptidase (S08 family) 0.0247 0.0413 0.0413
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0015 0.0015
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0015 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0015 0.0015
Echinococcus granulosus protein will die slowly 0.0071 0.0077 0.0077
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Brugia malayi putative neuropeptide receptor NPR1 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus granulosus beta tubulin 0.0048 0.0033 0.0033
Echinococcus multilocularis tubulin subunit beta 0.0048 0.0033 0.0042
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0038 0.0015 0.0015
Onchocerca volvulus 0.0038 0.0015 0.0375
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Brugia malayi larval opioid receptor 0.0038 0.0015 0.0015
Brugia malayi Serotonin receptor 0.0038 0.0015 0.0015
Schistosoma mansoni neuropeptide receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) SPRY domain-containing protein 0.0044 0.0025 0.0025
Brugia malayi hypothetical protein 0.0038 0.0015 0.0015
Plasmodium falciparum subtilisin-like protease 1 0.0247 0.0413 1
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.112 0.2073 0.365
Trypanosoma cruzi subtilisin peptidase 0.0247 0.0413 1
Plasmodium vivax tubulin beta chain, putative 0.0048 0.0033 0.0799
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0348 0.0604 0.0604
Trichomonas vaginalis conserved hypothetical protein 0.112 0.2073 0.365
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0247 0.0413 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0038 0.0015 0.0015
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Echinococcus granulosus neuropeptide receptor 0.0038 0.0015 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0015 0.002
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0348 0.0604 0.1064
Schistosoma mansoni hypothetical protein 0.0038 0.0015 0.0015
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0038 0.0015 0.0015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0015 0.0015
Trypanosoma brucei beta tubulin 0.0048 0.0033 0.0799
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0038 0.0015 0.0015
Leishmania major subtilisin-like serine peptidase 0.0247 0.0413 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0015 0.0015
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0015 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0015 0.0015
Schistosoma mansoni neuropeptide receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0015 0.0015
Echinococcus granulosus wd40 repeat 0.0075 0.0086 0.0086
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0015 0.002
Brugia malayi Dopamine receptor protein 2 0.0038 0.0015 0.0015
Brugia malayi Kringle domain containing protein 0.0061 0.0058 0.0058
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.122 0.2264 0.3986
Trypanosoma brucei subtilisin peptidase 0.0247 0.0413 1
Entamoeba histolytica tubulin family protein 0.0048 0.0033 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0247 0.0413 0.0728
Brugia malayi RE15519p 0.0038 0.0015 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0015 0.002
Brugia malayi hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) tubulin beta-4 chain 0.0048 0.0033 0.0033
Loa Loa (eye worm) TYRA-2 protein 0.0038 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0019 0.0033
Brugia malayi Subtilase family protein 0.0247 0.0413 0.0413
Echinococcus multilocularis glycoprotein Antigen 5 0.0054 0.0045 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0015 0.002
Trichomonas vaginalis conserved hypothetical protein 0.112 0.2073 0.365
Brugia malayi G-protein coupled receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.0058
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0061 0.0058 0.1395
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus multilocularis tubulin beta 1 chain 0.0048 0.0033 0.0042
Brugia malayi ORL1-like opioid receptor 0.0038 0.0015 0.0015
Trypanosoma brucei beta tubulin 0.0048 0.0033 0.0799
Echinococcus granulosus tachykinin peptides receptor 99D 0.0038 0.0015 0.0015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Echinococcus multilocularis Tubulin beta 2C chain 0.0048 0.0033 0.0042
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0015 0.0015
Toxoplasma gondii beta-1 tubulin, putative 0.0048 0.0033 0.0742
Onchocerca volvulus Huntingtin homolog 0.0103 0.0138 0.3341
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Echinococcus granulosus Furin 1 0.1468 0.2735 0.2735
Onchocerca volvulus 0.0038 0.0015 0.0375
Schistosoma mansoni hypothetical protein 0.112 0.2073 0.2073
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0015 0.002
Onchocerca volvulus 0.0071 0.0077 0.1861
Echinococcus granulosus enteropeptidase 0.0054 0.0045 0.0045
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0025 0.0615
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0038 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Schistosoma mansoni biogenic amine receptor 0.0038 0.0015 0.0015
Onchocerca volvulus 0.0038 0.0015 0.0375
Schistosoma mansoni tubulin subunit beta 0.0048 0.0033 0.0033
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0038 0.0015 0.0015
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0015 0.002
Brugia malayi hypothetical protein 0.0038 0.0015 0.0015
Echinococcus granulosus orexin receptor type 2 0.0038 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0015 0.0015
Brugia malayi Tachykinin-like peptides receptor 99D 0.0038 0.0015 0.0015
Echinococcus multilocularis neuroendocrine convertase 2 0.3739 0.7055 0.8964
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0015 0.002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0106 0.0144 0.0144
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0038 0.0015 0.0375
Echinococcus granulosus alpha 1A adrenergic receptor 0.0038 0.0015 0.0015
Onchocerca volvulus 0.0038 0.0015 0.0375
Echinococcus multilocularis wd40 repeat 0.0075 0.0086 0.0109
Echinococcus granulosus hypothetical protein 0.0038 0.0015 0.0015
Schistosoma mansoni biogenic amine receptor 0.0038 0.0015 0.0015
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.068 0.1237 0.1571
Echinococcus granulosus neuropeptide receptor A26 0.0038 0.0015 0.0015
Echinococcus multilocularis G protein coupled receptor 139 0.0038 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0103 0.0138 0.0138
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0038 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0086 0.0151
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Onchocerca volvulus 0.0089 0.0111 0.2698
Brugia malayi neuropeptide F receptor 0.0038 0.0015 0.0015
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0015 0.002
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0247 0.0413 1
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0015 0.002
Echinococcus multilocularis set1:ash2 histone methyltransferase complex 0.0044 0.0025 0.0032
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Schistosoma mansoni amine GPCR 0.0038 0.0015 0.0015
Echinococcus multilocularis protein will die slowly 0.0071 0.0077 0.0098
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0247 0.0413 0.0413
Echinococcus granulosus G protein coupled receptor 139 0.0038 0.0015 0.0015
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0247 0.0413 1
Onchocerca volvulus 0.0106 0.0144 0.3481
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0038 0.0015 0.002
Loa Loa (eye worm) proprotein convertase 2 0.1468 0.2735 0.2735
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0247 0.0413 1
Echinococcus granulosus sex peptide receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Brugia malayi Trypsin family protein 0.0106 0.0144 0.0144
Schistosoma mansoni myosin xvIII 0.0038 0.0015 0.0015
Loa Loa (eye worm) tubulin beta chain 0.0048 0.0033 0.0033
Toxoplasma gondii subtilisin SUB12 0.0264 0.0445 1
Toxoplasma gondii subtilisin SUB10 0.0247 0.0413 0.9293
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Echinococcus granulosus g-protein coupled receptor 0.0038 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0061 0.0058 0.0058
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0247 0.0413 1
Brugia malayi Melatonin receptor type 1A 0.0038 0.0015 0.0015
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0175 0.0275 0.0275
Trichomonas vaginalis tubulin gamma chain, putative 0.0048 0.0033 0.0058
Trichomonas vaginalis tubulin, putative 0.0048 0.0033 0.0058
Toxoplasma gondii subtilisin SUB11 0.0247 0.0413 0.9293
Echinococcus multilocularis serotonin receptor 0.0038 0.0015 0.002
Schistosoma mansoni adenoreceptor 0.0038 0.0015 0.0015
Leishmania major hypothetical protein, conserved 0.0061 0.0058 0.1395
Onchocerca volvulus 0.0038 0.0015 0.0375
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Brugia malayi neuropeptide F receptor 0.0038 0.0015 0.0015
Echinococcus multilocularis 0.4167 0.787 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0038 0.0015 0.002
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.3016 0.568 0.7218
Echinococcus multilocularis neuropeptide s receptor 0.0038 0.0015 0.002
Brugia malayi hypothetical protein 0.0038 0.0015 0.0015
Toxoplasma gondii subtilisin SUB8 0.0247 0.0413 0.9293
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0015 0.0015
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0015 0.0015
Brugia malayi Hypothetical WD-repeat protein F21H12.1 in chromosome II 0.0075 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0015 0.002
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0038 0.0015 0.0015
Echinococcus granulosus g protein coupled receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus granulosus Tubulin beta 2C chain 0.0048 0.0033 0.0033
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0015 0.0015
Brugia malayi sulfakinin receptor protein 0.0038 0.0015 0.0015
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0247 0.0413 1
Onchocerca volvulus 0.0038 0.0015 0.0375
Echinococcus multilocularis beta tubulin 0.0048 0.0033 0.0042
Echinococcus multilocularis g-protein coupled receptor 0.0038 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0247 0.0413 0.0413
Brugia malayi Serotonin receptor 0.0038 0.0015 0.0015
Toxoplasma gondii subtilisin SUB9 0.0247 0.0413 0.9293
Onchocerca volvulus 0.0038 0.0015 0.0375
Trichomonas vaginalis conserved hypothetical protein 0.112 0.2073 0.365
Echinococcus multilocularis beta tubulin 0.0048 0.0033 0.0042
Loa Loa (eye worm) hypothetical protein 0.5287 1 1
Schistosoma mansoni tubulin subunit beta 0.0048 0.0033 0.0033
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0015 0.002
Echinococcus multilocularis dro:myosuppressin receptor 0.0038 0.0015 0.002
Loa Loa (eye worm) TK/EGFR protein kinase 0.0458 0.0813 0.0813
Trichomonas vaginalis hypothetical protein 0.112 0.2073 0.365
Onchocerca volvulus 0.0038 0.0015 0.0375
Entamoeba histolytica tubulin family protein 0.0048 0.0033 0.5
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0038 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0015 0.0015
Echinococcus granulosus neuropeptide FF receptor 2 0.0038 0.0015 0.0015
Onchocerca volvulus 0.0038 0.0015 0.0375
Loa Loa (eye worm) hypothetical protein 0.0106 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.112 0.2073 0.365
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0015 0.002
Plasmodium vivax subtilisin-like protease 2, putative 0.0247 0.0413 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0038 0.0015 0.0015
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Schistosoma mansoni tyrosine kinase 0.0458 0.0813 0.0813
Echinococcus multilocularis Tubulin beta 2C chain 0.0048 0.0033 0.0042
Schistosoma mansoni hypothetical protein 0.0071 0.0077 0.0077
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0015 0.0015
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0247 0.0413 1
Echinococcus granulosus Tubulin beta 2C chain 0.0048 0.0033 0.0033
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0193 0.031 0.7493
Trypanosoma brucei beta tubulin 0.0048 0.0033 0.0799
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0106 0.0144 0.0144
Echinococcus granulosus 7tm_1 domain containing protein 0.0038 0.0015 0.0015
Plasmodium falciparum tubulin beta chain 0.0048 0.0033 0.0196
Loa Loa (eye worm) BEN-1 protein 0.0048 0.0033 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0247 0.0413 0.0728
Echinococcus granulosus dro:myosuppressin receptor 0.0038 0.0015 0.0015
Schistosoma mansoni trithorax protein ash2 0.0044 0.0025 0.0025
Brugia malayi Pre-SET motif family protein 0.0175 0.0275 0.0275
Schistosoma mansoni opsin-like receptor 0.0038 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0015 0.0015
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) tubulin beta-2A chain 0.0048 0.0033 0.0033
Brugia malayi hypothetical protein 0.0038 0.0015 0.0015
Echinococcus granulosus Mastin 0.0054 0.0045 0.0045
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0247 0.0413 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0015 0.0015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1468 0.2735 0.4814
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0015 0.0015
Schistosoma mansoni alpha-1 adrenergic receptor 0.0038 0.0015 0.0015
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0038 0.0015 0.0015
Brugia malayi putative neuropeptide receptor 0.0038 0.0015 0.0015
Echinococcus multilocularis enteropeptidase 0.0054 0.0045 0.0058
Trichomonas vaginalis tubulin beta chain, putative 0.0048 0.0033 0.0058
Echinococcus multilocularis serotonin receptor 0.0038 0.0015 0.002
Brugia malayi G protein-coupled receptor F59B2.13 0.0038 0.0015 0.0015
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Loa Loa (eye worm) melatonin receptor type 1A 0.0038 0.0015 0.0015
Echinococcus granulosus neuropeptide receptor 0.0038 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0038 0.0015 0.0015
Echinococcus granulosus glycoprotein Antigen 5 0.0054 0.0045 0.0045
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Echinococcus granulosus tubulin beta 4A class IVa 0.0048 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Leishmania major beta tubulin 0.0048 0.0033 0.0799
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0247 0.0413 0.0728
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Onchocerca volvulus 0.0061 0.0058 0.1395
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1468 0.2735 0.4814
Echinococcus multilocularis neuropeptide FF receptor 2 0.0038 0.0015 0.002
Brugia malayi Dopamine receptor 0.0038 0.0015 0.0015
Trichomonas vaginalis tubulin epsilon chain, putative 0.0048 0.0033 0.0058
Loa Loa (eye worm) hypothetical protein 0.0038 0.0015 0.0015
Toxoplasma gondii subtilisin SUB4 0.0247 0.0413 0.9293
Loa Loa (eye worm) hypothetical protein 0.0103 0.0138 0.0138
Echinococcus multilocularis Tubulin beta 2C chain 0.0048 0.0033 0.0042

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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