Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Peroxidase homolog | 0.0089 | 1 | 0.5 |
Onchocerca volvulus | Peroxidase homolog | 0.0089 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0089 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0089 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0089 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0089 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0045 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0089 | 1 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0 | 0.5 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0089 | 1 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0089 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0 | 0.5 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0045 | 0 | 0.5 |
Onchocerca volvulus | 0.0089 | 1 | 0.5 | |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0045 | 0 | 0.5 |
Echinococcus granulosus | peroxidasin | 0.0089 | 1 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0045 | 0 | 0.5 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Onchocerca volvulus | 0.0089 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Brugia malayi | Peroxidasin | 0.0089 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0045 | 0 | 0.5 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0089 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Onchocerca volvulus | 0.0089 | 1 | 0.5 | |
Onchocerca volvulus | Dual oxidase homolog | 0.0089 | 1 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0089 | 1 | 0.5 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0045 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0089 | 1 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0089 | 1 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0045 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.