Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | ecdysone induced protein 78C | 0.0242 | 0.0411 | 0.0963 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0242 | 0.0411 | 0.0427 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0242 | 0.0411 | 0.0815 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0411 | 0.0427 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0242 | 0.0411 | 0.0411 |
Schistosoma mansoni | coup transcription factor | 0.0242 | 0.0411 | 0.0815 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.3106 | 0.9633 | 0.9633 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0242 | 0.0411 | 0.0815 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.0044 | 0.0046 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0242 | 0.0411 | 0.0815 |
Brugia malayi | ecdysteroid receptor | 0.0242 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0411 | 0.0427 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0242 | 0.0411 | 0.0427 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0242 | 0.0411 | 0.0815 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0242 | 0.0411 | 0.0427 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0242 | 0.0411 | 0.0815 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0128 | 0.0044 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.0044 | 0.0046 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0242 | 0.0411 | 0.0963 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0242 | 0.0411 | 0.0963 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0411 | 0.0427 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.144 | 0.427 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.1682 | 0.5049 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.1682 | 0.5049 | 1 |
Schistosoma mansoni | hypothetical protein | 0.144 | 0.427 | 0.8458 |
Loa Loa (eye worm) | hypothetical protein | 0.3092 | 0.9589 | 0.9954 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0242 | 0.0411 | 0.0411 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0242 | 0.0411 | 0.0815 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.0044 | 0.0046 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0242 | 0.0411 | 0.0815 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0242 | 0.0411 | 0.0815 |
Brugia malayi | nuclear receptor RXR | 0.0128 | 0.0044 | 0.0044 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0242 | 0.0411 | 0.0411 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0242 | 0.0411 | 0.0411 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0242 | 0.0411 | 0.0963 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0242 | 0.0411 | 0.0411 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0242 | 0.0411 | 0.0815 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0242 | 0.0411 | 0.0411 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0128 | 0.0044 | 0.0103 |
Brugia malayi | nuclear receptor NHR-88 | 0.0242 | 0.0411 | 0.0411 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0242 | 0.0411 | 0.0963 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0242 | 0.0411 | 0.0815 |
Brugia malayi | nuclear hormone receptor | 0.0242 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0242 | 0.0411 | 0.0427 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0242 | 0.0411 | 0.0963 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0128 | 0.0044 | 0.0087 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0242 | 0.0411 | 0.0411 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0242 | 0.0411 | 0.0963 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0411 | 0.0427 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0242 | 0.0411 | 0.0815 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0242 | 0.0411 | 0.0411 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0242 | 0.0411 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0411 | 0.0427 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0128 | 0.0044 | 0.0087 |
Brugia malayi | steroid hormone receptor | 0.0242 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0242 | 0.0411 | 0.0427 |
Schistosoma mansoni | nuclear hormone receptor | 0.0242 | 0.0411 | 0.0815 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0242 | 0.0411 | 0.0427 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0242 | 0.0411 | 0.0815 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0242 | 0.0411 | 0.0815 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0242 | 0.0411 | 0.0411 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0242 | 0.0411 | 0.0963 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0242 | 0.0411 | 0.0815 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.0044 | 0.0046 |
Schistosoma mansoni | thyroid hormone receptor | 0.1682 | 0.5049 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0411 | 0.0427 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0242 | 0.0411 | 0.0411 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0242 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0411 | 0.0427 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0242 | 0.0411 | 0.0411 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0242 | 0.0411 | 0.0411 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0242 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.3106 | 0.9633 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0411 | 0.0427 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0242 | 0.0411 | 0.0815 |
Brugia malayi | hypothetical protein | 0.0128 | 0.0044 | 0.0044 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0242 | 0.0411 | 0.0815 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0242 | 0.0411 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0242 | 0.0411 | 0.0427 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0242 | 0.0411 | 0.0427 |
Brugia malayi | hypothetical protein | 0.0128 | 0.0044 | 0.0044 |
Onchocerca volvulus | 0.0242 | 0.0411 | 1 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.3106 | 0.9633 | 0.9633 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.144 | 0.427 | 0.8458 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0242 | 0.0411 | 0.0411 |
Echinococcus granulosus | FTZ F1 alpha | 0.0242 | 0.0411 | 0.0963 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0242 | 0.0411 | 0.0815 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.0044 | 0.0046 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0242 | 0.0411 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.