Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0757 | 0.0757 |
Wolbachia endosymbiont of Brugia malayi | NADH dehydrogenase subunit H | 0.0146 | 0.2619 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0268 | 0.5787 | 0.5787 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0128 | 0.2146 | 0.5 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0128 | 0.2146 | 0.2146 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0075 | 0.0757 | 0.0757 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0075 | 0.0757 | 0.0757 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0075 | 0.0757 | 0.0757 |
Toxoplasma gondii | hypothetical protein | 0.0075 | 0.0757 | 0.5 |
Onchocerca volvulus | 0.0075 | 0.0757 | 0.3526 | |
Echinococcus granulosus | serotonin transporter | 0.0128 | 0.2146 | 0.2146 |
Echinococcus granulosus | acetylcholinesterase | 0.0268 | 0.5787 | 0.5787 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0075 | 0.0757 | 0.1308 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.2146 | 0.2146 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0075 | 0.0757 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0757 | 0.0757 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0075 | 0.0757 | 0.0757 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0075 | 0.0757 | 0.0757 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0075 | 0.0757 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0268 | 0.5787 | 0.5787 |
Onchocerca volvulus | 0.0128 | 0.2146 | 1 | |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0075 | 0.0757 | 0.0757 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0075 | 0.0757 | 0.5 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0128 | 0.2146 | 0.2146 |
Toxoplasma gondii | hypothetical protein | 0.0075 | 0.0757 | 0.5 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0075 | 0.0757 | 0.0757 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0128 | 0.2146 | 0.3708 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0075 | 0.0757 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.2146 | 0.2146 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0431 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0268 | 0.5787 | 0.5787 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0075 | 0.0757 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.5787 | 0.5787 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.2146 | 0.2146 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0268 | 0.5787 | 0.5787 |
Brugia malayi | Carboxylesterase family protein | 0.0268 | 0.5787 | 1 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0075 | 0.0757 | 0.0757 |
Plasmodium falciparum | transporter, putative | 0.0075 | 0.0757 | 0.5 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0075 | 0.0757 | 0.0757 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0075 | 0.0757 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0757 | 0.0757 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0431 | 1 | 1 |
Plasmodium vivax | amine transporter, putative | 0.0075 | 0.0757 | 0.5 |
Onchocerca volvulus | 0.0075 | 0.0757 | 0.3526 | |
Onchocerca volvulus | 0.0075 | 0.0757 | 0.3526 | |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0075 | 0.0757 | 0.5 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0431 | 1 | 1 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0075 | 0.0757 | 0.0757 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0045 | 0 | 0.5 |
Mycobacterium ulcerans | NADH dehydrogenase subunit H | 0.0146 | 0.2619 | 1 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0128 | 0.2146 | 0.2146 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0075 | 0.0757 | 0.0757 |
Echinococcus multilocularis | serotonin transporter | 0.0128 | 0.2146 | 0.2146 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.2619 | 0.2619 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0757 | 0.0757 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0075 | 0.0757 | 0.0757 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0431 | 1 | 1 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0075 | 0.0757 | 0.0757 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0268 | 0.5787 | 0.5787 |
Brugia malayi | hypothetical protein | 0.0075 | 0.0757 | 0.1308 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0075 | 0.0757 | 0.1308 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H) | 0.0146 | 0.2619 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0268 | 0.5787 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0075 | 0.0757 | 0.1308 |
Plasmodium falciparum | amino acid transporter, putative | 0.0075 | 0.0757 | 0.5 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0075 | 0.0757 | 0.1308 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0757 | 0.0757 |
Echinococcus multilocularis | acetylcholinesterase | 0.0268 | 0.5787 | 0.5787 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0075 | 0.0757 | 0.0757 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0075 | 0.0757 | 0.0757 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0045 | 0 | 0.5 |
Loa Loa (eye worm) | serotonin transporter b | 0.0128 | 0.2146 | 0.2146 |
Plasmodium vivax | hypothetical protein, conserved | 0.0075 | 0.0757 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0268 | 0.5787 | 0.5787 |
Loa Loa (eye worm) | carboxylesterase | 0.0268 | 0.5787 | 0.5787 |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.5787 | 0.5787 |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 1 | 1 |
Echinococcus granulosus | NADH dehydrogenase subunit 1 | 0.0146 | 0.2619 | 0.2619 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0128 | 0.2146 | 0.2146 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0075 | 0.0757 | 0.0757 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.