Detailed information for compound 889583

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 428.333 | Formula: C18H19Cl2N3O3S
  • H donors: 1 H acceptors: 3 LogP: 3.27 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC(=O)C1CCN(CC1)C(=O)c1csc(n1)COc1ccc(cc1Cl)Cl
  • InChi: 1S/C18H19Cl2N3O3S/c1-21-17(24)11-4-6-23(7-5-11)18(25)14-10-27-16(22-14)9-26-15-3-2-12(19)8-13(15)20/h2-3,8,10-11H,4-7,9H2,1H3,(H,21,24)
  • InChiKey: BTWOJJAFVBYQTE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0266 0.0735
Mycobacterium tuberculosis Probable transcriptional regulatory protein (LuxR-family) 0.0531 0.6046 1
Echinococcus multilocularis JmjC domain containing protein 4 0.0021 0.0048 0.0002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0066 0.0101
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0266 0.0735
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0021 0.0048 0.0025
Onchocerca volvulus 0.0077 0.0701 0.1809
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0135 0.1393 0.2245
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.0701 0.1091
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0021 0.0048 0.0025
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0489 0.555 0.9173
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0047 0.5
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.0701 0.1091
Onchocerca volvulus 0.0077 0.0701 0.1809
Toxoplasma gondii aldehyde dehydrogenase 0.0135 0.1393 1
Schistosoma mansoni phd/f-box containing protein 0.0021 0.0048 0.0008
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0209 0.0718
Trichomonas vaginalis chromobox protein, putative 0.0045 0.033 0.095
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0266 0.0366
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0701 1
Onchocerca volvulus Alhambra homolog 0.0065 0.0566 0.1333
Schistosoma mansoni jumonji domain containing protein 0.0021 0.0048 0.0008
Loa Loa (eye worm) hypothetical protein 0.0111 0.1112 0.3667
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1979 0.6475
Loa Loa (eye worm) hypothetical protein 0.0035 0.0209 0.0558
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Echinococcus multilocularis geminin 0.0188 0.2009 0.1972
Trichomonas vaginalis chromobox protein, putative 0.0045 0.033 0.095
Echinococcus granulosus phd:f box containing protein 0.0021 0.0048 0.0007
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0048 0.0006
Leishmania major hypothetical protein, conserved 0.0026 0.0109 0.0463
Echinococcus granulosus chromobox protein 1 0.0075 0.0678 0.2796
Echinococcus multilocularis peregrin 0.0065 0.0566 0.0522
Brugia malayi Pre-SET motif family protein 0.0035 0.0209 0.0707
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Brugia malayi chromobox protein homolog 3 0.0042 0.0293 0.0992
Brugia malayi MH2 domain containing protein 0.0128 0.1303 0.4415
Brugia malayi jmjC domain containing protein 0.0079 0.0727 0.2462
Loa Loa (eye worm) hypothetical protein 0.0026 0.0109 0.0215
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0048 0.0007
Toxoplasma gondii ABC1 family protein 0.0077 0.0701 0.4862
Schistosoma mansoni jumonji/arid domain-containing protein 0.0079 0.0727 0.3465
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0701 1
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0701 1
Onchocerca volvulus 0.0077 0.0701 0.1809
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0945 0.4576
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0701 0.2193
Echinococcus granulosus geminin 0.0188 0.2009 0.8692
Loa Loa (eye worm) hypothetical protein 0.0042 0.0293 0.0848
Schistosoma mansoni chromobox protein 0.0075 0.0678 0.3216
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0209 0.0826
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.1393 0.6862
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0945 0.0902
Schistosoma mansoni hypothetical protein 0.0021 0.0051 0.0024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0006
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0047 0.0158
Mycobacterium tuberculosis Possible nitrate/nitrite response transcriptional regulatory protein NarL 0.0531 0.6046 1
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Echinococcus granulosus jumonji domain containing protein 0.009 0.0865 0.3625
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0209 0.0826
Echinococcus multilocularis phd:f box containing protein 0.0021 0.0048 0.0002
Giardia lamblia PHD finger protein 15 0.0065 0.0566 1
Brugia malayi jmjC domain containing protein 0.0021 0.0048 0.0163
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0266 0.0735
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0048 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.0134 0.1379 0.4589
Brugia malayi hypothetical protein 0.0026 0.0109 0.0369
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0021 0.0048 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0051 0.0073
Plasmodium vivax SET domain protein, putative 0.0035 0.0209 0.2475
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Plasmodium vivax hypothetical protein, conserved 0.0065 0.0566 0.793
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.0701 0.1091
Mycobacterium tuberculosis Possible transcriptional regulatory protein 0.0531 0.6046 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0109 0.1202
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0109 0.0953
Brugia malayi jmjC domain containing protein 0.0213 0.2304 0.7809
Brugia malayi follicle stimulating hormone receptor 0.0248 0.2714 0.9198
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0109 0.0953
Brugia malayi beta-lactamase 0.0077 0.0701 0.2376
Brugia malayi beta-lactamase family protein 0.0077 0.0701 0.2376
Mycobacterium ulcerans two component transcriptional regulator 0.0531 0.6046 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0945 0.3092
Echinococcus granulosus lysine specific demethylase 6a 0.0021 0.0048 0.0007
Loa Loa (eye worm) beta-lactamase 0.0077 0.0701 0.2254
Brugia malayi Bromodomain containing protein 0.0065 0.0566 0.1917
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0266 0.3353
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0268 0.2951 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0268 0.2951 1
Echinococcus multilocularis chromobox protein 1 0.0075 0.0678 0.0634
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0021 0.0048 0.0012
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0048 0.0006
Mycobacterium ulcerans lipase LipD 0.0077 0.0701 0.1091
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0021 0.0051 0.0035
Plasmodium falciparum phd finger protein, putative 0.0065 0.0566 1
Brugia malayi Inositol-1 0.004 0.0266 0.0902
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0701 0.2193
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0021 0.0048 0.0025
Loa Loa (eye worm) inositol-1 0.004 0.0266 0.0756
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0006
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.0701 0.1091
Mycobacterium ulcerans hypothetical protein 0.0531 0.6046 1
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0266 0.0972
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0048 0.0006
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0678 0.2115
Toxoplasma gondii PHD-finger domain-containing protein 0.0065 0.0566 0.3855
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0135 0.1393 0.1353
Mycobacterium tuberculosis Conserved protein 0.0077 0.0701 0.1091
Mycobacterium ulcerans two component transcriptional regulatory protein DevR 0.0531 0.6046 1
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0701 0.2193
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0109 0.0953
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Mycobacterium ulcerans hypothetical protein 0.0077 0.0701 0.1091
Mycobacterium tuberculosis Possible two component transcriptional regulatory protein (probably LuxR-family) 0.0531 0.6046 1
Onchocerca volvulus 0.0275 0.3032 1
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0678 0.2173
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0149 0.0344
Loa Loa (eye worm) hypothetical protein 0.0021 0.0051 0.0016
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.0701 0.29
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0293 0.0825
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0945 0.4576
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0066 0.0225
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0109 0.0463
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0678 0.2115
Echinococcus granulosus peregrin 0.0065 0.0566 0.2299
Plasmodium vivax JmjC domain containing protein 0.0021 0.0048 0.0025
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.1303 0.4326
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0701 0.3336
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Echinococcus granulosus chromobox protein 1 0.0075 0.0678 0.2796
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.1393 0.6862
Brugia malayi jmjC domain containing protein 0.0021 0.0048 0.0163
Brugia malayi beta-lactamase family protein 0.0077 0.0701 0.2376
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0945 0.3201
Mycobacterium tuberculosis Conserved protein 0.0077 0.0701 0.1091
Onchocerca volvulus 0.0047 0.0352 0.0581
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0701 0.3336
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0213 0.2304 0.2268
Mycobacterium ulcerans beta-lactamase 0.0077 0.0701 0.1091
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0701 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0209 0.0163
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0248 0.2714 0.9185
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0945 0.3978
Leishmania major hypothetical protein, conserved 0.0077 0.0701 0.4862
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0135 0.1393 0.5964
Schistosoma mansoni inositol monophosphatase 0.004 0.0266 0.1118
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0065 0.0566 0.2645
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.1393 0.2245
Mycobacterium leprae Probable lipase LipE 0.0077 0.0701 0.083
Echinococcus multilocularis lysine specific demethylase 6a 0.0021 0.0048 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0109 0.1202
Loa Loa (eye worm) hypothetical protein 0.0065 0.0566 0.1788
Trichomonas vaginalis set domain proteins, putative 0.0275 0.3032 1
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0021 0.0051 0.0073
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0293 0.0373
Loa Loa (eye worm) jmjC domain-containing protein 0.0079 0.0727 0.2341
Echinococcus multilocularis lysine specific demethylase 5A 0.0079 0.0727 0.0683
Mycobacterium ulcerans putative regulatory protein 0.0531 0.6046 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.033 0.0504
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0194 0.0651
Brugia malayi jmjC domain containing protein 0.0021 0.0048 0.0163
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0047 0.0352 0.1556
Mycobacterium tuberculosis Probable transcriptional regulatory protein (probably LuxR/UhpA-family) 0.0531 0.6046 1
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0217 0.0285
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0209 0.1203
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0209 0.0826
Schistosoma mansoni jumonji/arid domain-containing protein 0.0079 0.0727 0.3465
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.0701 0.1091
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Schistosoma mansoni hypothetical protein 0.0188 0.2009 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0266 1
Echinococcus granulosus lysine specific demethylase 5A 0.0079 0.0727 0.3012
Mycobacterium leprae PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN 0.0531 0.6046 1
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0149 0.0344
Echinococcus multilocularis PHD finger protein rhinoceros 0.0065 0.0566 0.0522
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1979 0.6475
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0266 0.3353
Echinococcus multilocularis chromobox protein 1 0.0075 0.0678 0.0634
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.0701 0.2254
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.1303 0.4326
Leishmania major hypothetical protein, conserved 0.0021 0.0048 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0945 0.4576
Schistosoma mansoni hypothetical protein 0.0065 0.0566 0.2645
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.1393 0.2245
Brugia malayi AF-10 protein 0.0021 0.0051 0.0174
Schistosoma mansoni jumonji domain containing protein 0.0169 0.179 0.8884
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0266 0.163
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0945 0.0902
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0109 0.0953
Brugia malayi PHD-finger family protein 0.0021 0.0051 0.0174
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.0701 0.1091
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Echinococcus granulosus jumonji domain containing 1A 0.0021 0.0048 0.0007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.1393 0.2245
Schistosoma mansoni inositol monophosphatase 0.004 0.0266 0.1118
Loa Loa (eye worm) PHD-finger family protein 0.0065 0.0566 0.1788
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0266 0.163
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.0701 0.1091
Loa Loa (eye worm) hypothetical protein 0.0033 0.0187 0.0482
Echinococcus granulosus PHD finger protein rhinoceros 0.0065 0.0566 0.2299
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0266 0.0221
Schistosoma mansoni hypothetical protein 0.0188 0.2009 1
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Trichomonas vaginalis esterase, putative 0.0077 0.0701 0.2193
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0241 0.264 0.8927
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.0701 0.0658
Plasmodium falciparum JmjC domain-containing protein, putative 0.0021 0.0048 0.0032
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0266 1
Echinococcus multilocularis jumonji domain containing protein 0.009 0.0865 0.0822
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0213 0.2304 1
Brugia malayi jmjC domain containing protein 0.0021 0.0048 0.0163
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.0531 0.6046 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.0701 0.1091
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Brugia malayi Heterochromatin protein 1 0.0075 0.0678 0.2297
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0135 0.1393 1
Brugia malayi Pre-SET motif family protein 0.0241 0.264 0.8944
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0701 0.2193
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0945 0.3978
Mycobacterium ulcerans nitrate/nitrite response regulator protein NarL 0.0531 0.6046 1
Echinococcus multilocularis jumonji domain containing 1A 0.0021 0.0048 0.0002
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0021 0.0048 0.0008
Toxoplasma gondii PHD-finger domain-containing protein 0.0065 0.0566 0.3855
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0051 0.0035
Echinococcus granulosus JmjC domain containing protein 4 0.0021 0.0048 0.0007
Mycobacterium tuberculosis Conserved protein 0.0077 0.0701 0.1091
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0293 0.0825
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.0701 0.1091
Brugia malayi PHD-finger family protein 0.0065 0.0566 0.1917
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0701 0.2193
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.0701 0.2376
Schistosoma mansoni chromobox protein 0.0075 0.0678 0.3216
Onchocerca volvulus Glucosylceramidase homolog 0.0176 0.1868 0.591
Mycobacterium leprae conserved hypothetical protein 0.0077 0.0701 0.083
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0021 0.0051 0.0073
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0266 0.3353
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0209 0.0163
Schistosoma mansoni phosphatidylserine receptor 0.0021 0.0048 0.0008
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0021 0.0051 0.0092
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Schistosoma mansoni protein phosphatase 2C 0.0021 0.0048 0.0008

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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