Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | serotonin receptor | 0.0147 | 0 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.0147 | 0 | 0.5 |
Mycobacterium tuberculosis | 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) | 1.2333 | 1 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0147 | 0 | 0.5 |
Mycobacterium ulcerans | 3-dehydroquinate dehydratase | 1.2333 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0147 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.