Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.178 | 0.178 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.178 | 0.178 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.178 | 0.178 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0011 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0065 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.178 | 0.178 |
Echinococcus multilocularis | acetylcholinesterase | 0.0065 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0065 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0.178 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.178 | 0.178 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.178 | 0.178 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.178 | 0.178 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.178 | 0.178 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.178 | 0.178 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.178 | 0.178 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.178 | 0.178 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.178 | 0.178 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0.178 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.178 | 0.178 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.178 | 0.178 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.178 | 0.178 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.178 | 0.178 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.178 | 0.178 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.178 | 0.178 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.178 | 0.178 |
Echinococcus granulosus | carboxylesterase 5A | 0.0065 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.178 | 0.178 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.178 | 0.178 |
Echinococcus granulosus | acetylcholinesterase | 0.0065 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0065 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.178 | 0.178 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.178 | 0.178 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.178 | 0.178 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.178 | 0.178 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.178 | 0.178 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.178 | 0.178 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.178 | 0.178 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.178 | 0.178 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0011 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.178 | 0.178 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0065 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.178 | 0.178 |
Echinococcus granulosus | acetylcholinesterase | 0.0065 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.178 | 0.178 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.178 | 0.178 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0011 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.178 | 0.178 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0.178 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.178 | 0.178 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.178 | 0.178 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0011 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.178 | 0.178 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.178 | 0.178 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.178 | 0.178 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.178 | 0.178 |
Onchocerca volvulus | 0.0021 | 0.178 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0011 | 0 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.178 | 0.178 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.178 | 0.178 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.178 | 0.178 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.178 | 0.178 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.178 | 0.178 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.178 | 0.178 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.178 | 0.178 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.178 | 0.178 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0011 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0065 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.178 | 0.178 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.178 | 0.178 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.178 | 0.178 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.178 | 0.178 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.