Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0068 | 0.5895 | 0.5895 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0102 | 1 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0068 | 0.5895 | 0.5895 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0045 | 0.3064 | 1 |
Brugia malayi | Melibiase family protein | 0.0068 | 0.5895 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0045 | 0.3064 | 0.5198 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | DNA polymerase eta | 0.0045 | 0.3064 | 0.3064 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0102 | 1 | 1 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0068 | 0.5895 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0102 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.3064 | 0.5198 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.0102 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.5895 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0102 | 1 | 1 |
Toxoplasma gondii | melibiase subfamily protein | 0.0102 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0031 | 0.1463 | 0.4775 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0 | 0.5 |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.0102 | 1 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0045 | 0.3064 | 0.3064 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0031 | 0.1463 | 0.4775 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0045 | 0.3064 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0045 | 0.3064 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0045 | 0.3064 | 0.3064 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.