Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3998 | 0.3998 |
Brugia malayi | Cytochrome P450 family protein | 0.0053 | 0.1681 | 0.1321 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0072 | 0.3278 | 0.277 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0072 | 0.3278 | 0.3278 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0152 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0072 | 0.3278 | 0.2988 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.008 | 0.3998 | 0.3739 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0072 | 0.3278 | 0.3278 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0035 | 0.0208 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0152 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.008 | 0.3998 | 0.3544 |
Onchocerca volvulus | 0.0152 | 1 | 1 | |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0072 | 0.3278 | 0.3278 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0152 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0152 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.008 | 0.3998 | 0.3739 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.008 | 0.3998 | 0.3739 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0072 | 0.3278 | 0.2988 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0072 | 0.3278 | 0.2988 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0152 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0152 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0152 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0152 | 1 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0072 | 0.3278 | 0.2988 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0152 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0152 | 1 | 1 |
Brugia malayi | ecdysone receptor | 0.0072 | 0.3278 | 0.2988 |
Brugia malayi | nuclear receptor NHR-88 | 0.0152 | 1 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0072 | 0.3278 | 0.2988 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0152 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0072 | 0.3278 | 0.277 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0072 | 0.3278 | 0.2988 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3998 | 0.3998 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3998 | 0.3998 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0152 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0152 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0152 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0152 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0072 | 0.3278 | 0.2988 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0152 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0152 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0152 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0072 | 0.3278 | 0.2988 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0035 | 0.0208 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0152 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0152 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.008 | 0.3998 | 0.3739 |
Loa Loa (eye worm) | DR-78 | 0.0072 | 0.3278 | 0.3278 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0152 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0152 | 1 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0072 | 0.3278 | 0.2988 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 1 | 1 |
Brugia malayi | tailless protein | 0.0072 | 0.3278 | 0.2988 |
Brugia malayi | nuclear receptor NHR-88 | 0.0072 | 0.3278 | 0.2988 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0072 | 0.3278 | 0.2988 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0053 | 0.1681 | 0.1681 |
Brugia malayi | nuclear receptor NHR-67 | 0.0072 | 0.3278 | 0.2988 |
Schistosoma mansoni | zinc finger protein | 0.0072 | 0.3278 | 0.277 |
Brugia malayi | hypothetical protein | 0.0072 | 0.3278 | 0.2988 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0152 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0152 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0152 | 1 | 1 |
Brugia malayi | conserved hypotetical protein | 0.0072 | 0.3278 | 0.2988 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0152 | 1 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0072 | 0.3278 | 0.277 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0072 | 0.3278 | 0.2988 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3998 | 0.3998 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0152 | 1 | 1 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0072 | 0.3278 | 0.2988 |
Brugia malayi | nuclear receptor RXR | 0.0072 | 0.3278 | 0.2988 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0072 | 0.3278 | 0.2988 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.008 | 0.3998 | 0.3998 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0152 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0152 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0072 | 0.3278 | 0.277 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0072 | 0.3278 | 0.2988 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0072 | 0.3278 | 0.2988 |
Brugia malayi | nuclear receptor RXR | 0.008 | 0.3998 | 0.3739 |
Brugia malayi | hypothetical protein | 0.0072 | 0.3278 | 0.2988 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0152 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0152 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0152 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Schistosoma mansoni | nuclear receptor | 0.0072 | 0.3278 | 0.277 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0072 | 0.3278 | 0.2988 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0152 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.008 | 0.3998 | 0.3544 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.008 | 0.3998 | 0.3739 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0152 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0152 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0072 | 0.3278 | 0.2988 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0152 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0152 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Schistosoma mansoni | nuclear receptor | 0.0072 | 0.3278 | 0.277 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0152 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.008 | 0.3998 | 0.3739 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0072 | 0.3278 | 0.277 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0152 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0038 | 0.0414 | 0.0414 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3998 | 0.3998 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0152 | 1 | 1 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0072 | 0.3278 | 0.2988 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3278 | 0.3278 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0072 | 0.3278 | 0.2988 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0152 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.