TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 428.438 | Formula: C21H24N4O6
H donors: 1 H acceptors: 5 LogP: 2.05 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: CC(COC(=C1C(=Nc2c(C1c1ccc(cc1)[N+](=O)[O-])c(=O)n(c(=O)n2C)C)C)O)C
InChi: 1S/C21H24N4O6/c1-11(2)10-31-20(27)15-12(3)22-18-17(19(26)24(5)21(28)23(18)4)16(15)13-6-8-14(9-7-13)25(29)30/h6-9,11,16,27H,10H2,1-5H3
InChiKey: QTIJLPRKOZRQJJ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	g protein coupled receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0084	0.9421	0.5
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Brugia malayi	putative neuropeptide receptor NPR1	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	tm gpcr rhodopsin	0.0084	0.9421	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0084	0.9421	0.5
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	sex peptide receptor	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Schistosoma mansoni	amine GPCR	0.0084	0.9421	0.5
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0084	0.9421	0.5
Echinococcus granulosus	tm gpcr rhodopsin	0.0084	0.9421	0.5
Echinococcus multilocularis	g protein coupled receptor	0.0084	0.9421	0.5
Schistosoma mansoni	amine GPCR	0.0084	0.9421	0.5
Echinococcus multilocularis	g protein coupled receptor	0.0084	0.9421	0.5
Schistosoma mansoni	neuropeptide receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Echinococcus multilocularis	serotonin receptor	0.0084	0.9421	0.5
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0084	0.9421	0.5
Brugia malayi	hypothetical protein	0.0084	0.9421	0.5
Brugia malayi	follicle stimulating hormone receptor	0.0084	0.9421	0.5
Echinococcus granulosus	orexin receptor type 2	0.0084	0.9421	0.5
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0084	0.9421	0.5
Schistosoma mansoni	neuropeptide f receptor 76f	0.0084	0.9421	0.5
Echinococcus granulosus	neuropeptide receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Schistosoma mansoni	amine GPCR	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Schistosoma mansoni	biogenic amine receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0084	0.9421	0.5
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Echinococcus granulosus	somatostatin receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Schistosoma mansoni	neuropeptide F-like receptor	0.0084	0.9421	0.5
Brugia malayi	hypothetical protein	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0084	0.9421	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0084	0.9421	0.5
Brugia malayi	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0084	0.9421	0.5
Brugia malayi	hypothetical protein	0.0084	0.9421	0.5
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Schistosoma mansoni	neuropeptide receptor	0.0084	0.9421	0.5
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0084	0.9421	0.5
Brugia malayi	hypothetical protein	0.0084	0.9421	0.5
Brugia malayi	Dopamine receptor protein 2	0.0084	0.9421	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Echinococcus granulosus	neuropeptide s receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Schistosoma mansoni	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0084	0.9421	0.5
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	neuropeptide Y receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	G protein coupled receptor 139	0.0084	0.9421	0.5
Echinococcus granulosus	sex peptide receptor	0.0084	0.9421	0.5
Echinococcus granulosus	hypothetical protein	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Loa Loa (eye worm)	G-protein coupled receptor	0.0084	0.9421	0.5
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	g-protein coupled receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	neuropeptide Y receptor	0.0084	0.9421	0.5
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0084	0.9421	0.5
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0084	0.9421	0.5
Schistosoma mansoni	neuropeptide receptor	0.0084	0.9421	0.5
Schistosoma mansoni	histamine h1 receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	neuropeptides capa receptor	0.0084	0.9421	0.5
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0084	0.9421	0.5
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0084	0.9421	0.5
Schistosoma mansoni	adenoreceptor	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Brugia malayi	ORL1-like opioid receptor	0.0084	0.9421	0.5
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0084	0.9421	0.5
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0084	0.9421	0.5
Schistosoma mansoni	growth hormone secretagogue receptor	0.0084	0.9421	0.5
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0084	0.9421	0.5
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Brugia malayi	Serotonin receptor	0.0084	0.9421	0.5
Brugia malayi	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	neuropeptide receptor	0.0084	0.9421	0.5
Echinococcus granulosus	7tm_1 domain containing protein	0.0084	0.9421	0.5
Brugia malayi	G protein-coupled receptor F59B2.13	0.0084	0.9421	0.5
Echinococcus granulosus	allatostatin A receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Schistosoma mansoni	neuropeptide receptor	0.0084	0.9421	0.5
Brugia malayi	Melatonin receptor type 1A	0.0084	0.9421	0.5
Brugia malayi	G protein-coupled receptor	0.0084	0.9421	0.5
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.0085	1	1
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Schistosoma mansoni	opsin-like receptor	0.0084	0.9421	0.5
Brugia malayi	Serotonin receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	serotonin receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	allatostatin A receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0084	0.9421	0.5
Echinococcus granulosus	g-protein coupled receptor	0.0084	0.9421	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	neuropeptides capa receptor	0.0084	0.9421	0.5
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	melatonin receptor type 1A	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Brugia malayi	Dopamine receptor protein 1	0.0084	0.9421	0.5
Echinococcus granulosus	7TM GPCR rhodopsin	0.0084	0.9421	0.5
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0084	0.9421	0.5
Brugia malayi	neuropeptide F receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	g protein coupled receptor	0.0084	0.9421	0.5
Brugia malayi	GnHR receptor homolog	0.0084	0.9421	0.5
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.0085	1	1
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Brugia malayi	Dopamine receptor	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Brugia malayi	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Schistosoma mansoni	hypothetical protein	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Loa Loa (eye worm)	G-protein coupled receptor	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Schistosoma mansoni	hypothetical protein	0.0084	0.9421	0.5
Schistosoma mansoni	amine GPCR	0.0084	0.9421	0.5
Echinococcus granulosus	G protein coupled receptor 139	0.0084	0.9421	0.5
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0084	0.9421	0.5
Brugia malayi	hypothetical protein	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	orexin receptor type 2	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	g protein coupled receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	neuropeptide F receptor	0.0084	0.9421	0.5
Schistosoma mansoni	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0084	0.9421	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0084	0.9421	0.5
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0084	0.9421	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0084	0.9421	0.5
Loa Loa (eye worm)	TYRA-2 protein	0.0084	0.9421	0.5
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0084	0.9421	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0084	0.9421	0.5
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.0085	1	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	serotonin receptor	0.0084	0.9421	0.5
Schistosoma mansoni	neuropeptide F-like receptor	0.0084	0.9421	0.5
Schistosoma mansoni	amine GPCR	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0084	0.9421	0.5
Echinococcus multilocularis	neuropeptide s receptor	0.0084	0.9421	0.5
Brugia malayi	sulfakinin receptor protein	0.0084	0.9421	0.5
Giardia lamblia	NADPH oxidoreductase, putative	0.0085	1	0.5
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0084	0.9421	0.5
Schistosoma mansoni	opsin-like receptor	0.0084	0.9421	0.5
Schistosoma mansoni	myosin xvIII	0.0084	0.9421	0.5
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0084	0.9421	0.5
Echinococcus multilocularis	neuropeptide receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Onchocerca volvulus		0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0084	0.9421	0.5
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0084	0.9421	0.5
Echinococcus granulosus	neuropeptides capa receptor	0.0084	0.9421	0.5
Brugia malayi	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	biogenic amine 5HT receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Schistosoma mansoni	opsin-like receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0084	0.9421	0.5
Schistosoma mansoni	biogenic amine receptor	0.0084	0.9421	0.5
Echinococcus granulosus	g protein coupled receptor	0.0084	0.9421	0.5
Echinococcus granulosus	dro:myosuppressin receptor	0.0084	0.9421	0.5
Echinococcus granulosus	neuropeptide Y receptor	0.0084	0.9421	0.5
Brugia malayi	G-protein coupled receptor	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Echinococcus granulosus	fmrfamide receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	fmrfamide receptor	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Loa Loa (eye worm)	neuropeptide F receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0084	0.9421	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0084	0.9421	0.5
Echinococcus multilocularis	somatostatin receptor	0.0084	0.9421	0.5
Brugia malayi	G-protein coupled receptor	0.0084	0.9421	0.5
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0084	0.9421	0.5
Echinococcus granulosus	biogenic amine 5HT receptor	0.0084	0.9421	0.5
Brugia malayi	larval opioid receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Echinococcus granulosus	neuropeptides capa receptor	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Echinococcus multilocularis	neuropeptide receptor A26	0.0084	0.9421	0.5
Onchocerca volvulus		0.0084	0.9421	0.5
Echinococcus multilocularis	neuropeptide receptor	0.0084	0.9421	0.5
Giardia lamblia	NADPH oxidoreductase, putative	0.0085	1	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0085	1	1
Echinococcus multilocularis	dro:myosuppressin receptor	0.0084	0.9421	0.5
Echinococcus multilocularis	fmrfamide receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0084	0.9421	0.5
Brugia malayi	putative neuropeptide receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Brugia malayi	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	tm gpcr rhodopsin	0.0084	0.9421	0.5
Echinococcus granulosus	neuropeptide receptor A26	0.0084	0.9421	0.5
Echinococcus granulosus	neuropeptide FF receptor 2	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	neuropeptide Y receptor	0.0084	0.9421	0.5
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Brugia malayi	AKH receptor	0.0084	0.9421	0.5
Brugia malayi	neuropeptide F receptor	0.0084	0.9421	0.5
Schistosoma mansoni	biogenic amine receptor	0.0084	0.9421	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.9421	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0084	0.9421	0.5
Brugia malayi	RE15519p	0.0084	0.9421	0.5

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 891731