Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glutaminase, putative | 0.0265 | 0.8664 | 1 |
Loa Loa (eye worm) | glutaminase | 0.0265 | 0.8664 | 0.8664 |
Onchocerca volvulus | 0.005 | 0 | 0.5 | |
Onchocerca volvulus | 0.005 | 0 | 0.5 | |
Mycobacterium ulcerans | glutaminase | 0.0265 | 0.8664 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0298 | 1 | 1 |
Onchocerca volvulus | 0.005 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0298 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.005 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0298 | 1 | 1 |
Onchocerca volvulus | 0.005 | 0 | 0.5 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.0298 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0164 | 0.4598 | 0.4598 |
Echinococcus granulosus | geminin | 0.0164 | 0.4598 | 0.4598 |
Schistosoma mansoni | glutaminase | 0.0265 | 0.8664 | 0.8664 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.005 | 0 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0298 | 1 | 1 |
Brugia malayi | glutaminase DH11.1 | 0.0265 | 0.8664 | 0.8664 |
Onchocerca volvulus | 0.005 | 0 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.4598 | 0.4598 |
Loa Loa (eye worm) | carboxylesterase | 0.0298 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.0265 | 0.8664 | 0.8664 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.005 | 0 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0298 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.4598 | 0.4598 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.